Incidental Mutation 'IGL03301:Saal1'
| ID |
416235 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Saal1
|
| Ensembl Gene |
ENSMUSG00000006763 |
| Gene Name |
serum amyloid A-like 1 |
| Synonyms |
5031425D22Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.093)
|
| Stock # |
IGL03301
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
46336581-46360085 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 46351944 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000120658
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000143082]
|
| AlphaFold |
Q9D2C2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143082
|
| SMART Domains |
Protein: ENSMUSP00000120658
Gene: ENSMUSG00000006763
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
24 |
N/A |
INTRINSIC |
|
SCOP:d1gw5a_
|
40 |
455 |
2e-5 |
SMART |
|
low complexity region
|
456 |
465 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000209780
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000209797
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210628
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210791
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(6) : Gene trapped(6) |
| Other mutations in this stock |
Total: 30 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts3 |
T |
C |
5: 89,855,263 (GRCm39) |
E418G |
probably damaging |
Het |
| Arl14 |
T |
C |
3: 69,130,276 (GRCm39) |
F141S |
probably damaging |
Het |
| C1s1 |
A |
T |
6: 124,518,283 (GRCm39) |
|
probably benign |
Het |
| Cilp |
T |
C |
9: 65,187,499 (GRCm39) |
V1198A |
probably benign |
Het |
| Cnbd1 |
A |
T |
4: 19,055,039 (GRCm39) |
I129K |
probably benign |
Het |
| Ctdp1 |
G |
A |
18: 80,492,849 (GRCm39) |
Q549* |
probably null |
Het |
| Cyp2ab1 |
T |
A |
16: 20,132,549 (GRCm39) |
I250F |
possibly damaging |
Het |
| Dmd |
G |
A |
X: 82,952,120 (GRCm39) |
R1765Q |
probably damaging |
Het |
| Dnah1 |
C |
T |
14: 31,014,649 (GRCm39) |
G1739R |
probably damaging |
Het |
| Eml6 |
T |
C |
11: 29,714,083 (GRCm39) |
K1350E |
probably benign |
Het |
| Ephx4 |
C |
A |
5: 107,574,730 (GRCm39) |
T256K |
probably benign |
Het |
| Fnd3c2 |
G |
T |
X: 105,295,869 (GRCm39) |
Q49K |
probably benign |
Het |
| Heatr1 |
G |
T |
13: 12,449,086 (GRCm39) |
G1889W |
probably damaging |
Het |
| Igkv19-93 |
A |
T |
6: 68,713,465 (GRCm39) |
W55R |
probably damaging |
Het |
| Jak1 |
T |
C |
4: 101,032,370 (GRCm39) |
Y412C |
probably damaging |
Het |
| Moxd1 |
A |
T |
10: 24,155,382 (GRCm39) |
N261I |
probably damaging |
Het |
| Mrgpra1 |
T |
C |
7: 46,985,164 (GRCm39) |
N172D |
probably benign |
Het |
| Papolg |
T |
C |
11: 23,824,503 (GRCm39) |
N293S |
probably benign |
Het |
| Piezo2 |
A |
G |
18: 63,160,775 (GRCm39) |
S2294P |
probably damaging |
Het |
| Ppp3cb |
A |
T |
14: 20,574,052 (GRCm39) |
V262D |
probably damaging |
Het |
| Rhox7a |
A |
G |
X: 36,928,888 (GRCm39) |
T235A |
probably benign |
Het |
| Scrn1 |
G |
A |
6: 54,525,322 (GRCm39) |
R16* |
probably null |
Het |
| Slc22a2 |
A |
G |
17: 12,824,926 (GRCm39) |
R263G |
probably damaging |
Het |
| Speer3 |
T |
A |
5: 13,845,447 (GRCm39) |
L160H |
probably damaging |
Het |
| Tmcc2 |
T |
C |
1: 132,288,557 (GRCm39) |
M377V |
possibly damaging |
Het |
| Tsen2 |
T |
G |
6: 115,545,732 (GRCm39) |
Y341D |
probably damaging |
Het |
| Vmn2r13 |
A |
T |
5: 109,305,955 (GRCm39) |
V541D |
probably damaging |
Het |
| Vmn2r15 |
A |
G |
5: 109,445,221 (GRCm39) |
|
probably null |
Het |
| Zfp711 |
T |
C |
X: 111,543,098 (GRCm39) |
Y710H |
probably damaging |
Het |
| Zmiz2 |
C |
T |
11: 6,351,170 (GRCm39) |
T566M |
probably damaging |
Het |
|
| Other mutations in Saal1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02727:Saal1
|
APN |
7 |
46,339,223 (GRCm39) |
splice site |
probably null |
|
|
G5030:Saal1
|
UTSW |
7 |
46,342,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0021:Saal1
|
UTSW |
7 |
46,342,316 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0765:Saal1
|
UTSW |
7 |
46,349,071 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R1086:Saal1
|
UTSW |
7 |
46,338,883 (GRCm39) |
splice site |
probably benign |
|
|
R1273:Saal1
|
UTSW |
7 |
46,342,366 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1466:Saal1
|
UTSW |
7 |
46,351,969 (GRCm39) |
splice site |
probably null |
|
|
R1466:Saal1
|
UTSW |
7 |
46,351,969 (GRCm39) |
splice site |
probably null |
|
|
R1661:Saal1
|
UTSW |
7 |
46,342,224 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1695:Saal1
|
UTSW |
7 |
46,342,340 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2018:Saal1
|
UTSW |
7 |
46,348,913 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2058:Saal1
|
UTSW |
7 |
46,348,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2059:Saal1
|
UTSW |
7 |
46,348,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2326:Saal1
|
UTSW |
7 |
46,342,235 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4182:Saal1
|
UTSW |
7 |
46,360,076 (GRCm39) |
unclassified |
probably benign |
|
|
R4704:Saal1
|
UTSW |
7 |
46,349,164 (GRCm39) |
intron |
probably benign |
|
|
R4831:Saal1
|
UTSW |
7 |
46,349,071 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5270:Saal1
|
UTSW |
7 |
46,351,157 (GRCm39) |
intron |
probably benign |
|
|
R5471:Saal1
|
UTSW |
7 |
46,349,072 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5790:Saal1
|
UTSW |
7 |
46,351,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6699:Saal1
|
UTSW |
7 |
46,342,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6804:Saal1
|
UTSW |
7 |
46,349,064 (GRCm39) |
frame shift |
probably null |
|
|
R6934:Saal1
|
UTSW |
7 |
46,352,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7863:Saal1
|
UTSW |
7 |
46,342,327 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8076:Saal1
|
UTSW |
7 |
46,360,031 (GRCm39) |
missense |
probably benign |
|
|
R9340:Saal1
|
UTSW |
7 |
46,351,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2016-08-02 |
Incidental Mutation