Incidental Mutation 'IGL03302:Scgb2b7'
ID416241
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Scgb2b7
Ensembl Gene ENSMUSG00000094053
Gene Namesecretoglobin, family 2B, member 7
SynonymsAbpbg7, Gm4684
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL03302
Quality Score
Status
Chromosome7
Chromosomal Location31703779-31705757 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 31705081 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Serine at position 65 (C65S)
Ref Sequence ENSEMBL: ENSMUSP00000136731 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000178258]
Predicted Effect probably damaging
Transcript: ENSMUST00000178258
AA Change: C65S

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000136731
Gene: ENSMUSG00000094053
AA Change: C65S

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
Pfam:Feld-I_B 24 90 7.8e-33 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188968
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca8b T A 11: 109,967,750 Y542F possibly damaging Het
Ankrd34b A T 13: 92,439,643 N461I possibly damaging Het
Ccl24 T C 5: 135,570,878 K93E probably benign Het
Ccr9 T A 9: 123,779,536 D94E probably damaging Het
Cd79a G A 7: 24,899,334 V103M probably damaging Het
Ces1e A G 8: 93,223,893 probably null Het
Cul9 T C 17: 46,526,640 E993G probably damaging Het
Cyp4a14 T C 4: 115,491,378 I330V probably benign Het
Cyp7a1 T C 4: 6,273,801 D35G probably benign Het
Dmpk C A 7: 19,086,486 probably benign Het
Gcnt1 G T 19: 17,329,183 R393S probably benign Het
Lctl C T 9: 64,134,848 probably benign Het
Mttp A T 3: 138,104,707 I664N possibly damaging Het
Myh1 C T 11: 67,211,502 A873V probably benign Het
Nedd9 A G 13: 41,338,854 V54A probably damaging Het
Olfr1306 A T 2: 111,912,822 V36E possibly damaging Het
Olfr401 T G 11: 74,121,633 C115G possibly damaging Het
Olfr449 G T 6: 42,838,003 E41* probably null Het
Pak6 A T 2: 118,693,303 E313V probably benign Het
Pla2g4a A G 1: 149,864,947 S402P probably benign Het
Polq T C 16: 37,071,772 M2012T probably damaging Het
Ppp1r12b A T 1: 134,838,050 probably benign Het
Rbp3 A G 14: 33,954,659 H188R probably damaging Het
Rps6ka2 C A 17: 7,299,388 Q682K possibly damaging Het
Spag4 A G 2: 156,068,420 Q322R probably damaging Het
Spef2 T C 15: 9,676,380 T702A probably benign Het
Taf3 G T 2: 9,952,131 F408L probably damaging Het
Tead2 T G 7: 45,232,899 Y121D possibly damaging Het
Thegl T G 5: 77,054,576 S281R probably benign Het
Tmco5 A T 2: 116,892,279 T294S probably damaging Het
Trim37 A G 11: 87,147,001 E187G possibly damaging Het
Ubb T A 11: 62,552,417 L91Q probably damaging Het
Ugt2a3 G A 5: 87,336,580 P195L probably damaging Het
Zan T C 5: 137,468,390 S402G possibly damaging Het
Zc3h7a T A 16: 11,141,710 H793L probably damaging Het
Zfhx4 C T 3: 5,403,713 T2977I possibly damaging Het
Other mutations in Scgb2b7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01994:Scgb2b7 APN 7 31703984 missense probably benign 0.26
IGL03242:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03252:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03261:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03271:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03277:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03280:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03308:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03388:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03401:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03402:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
IGL03411:Scgb2b7 APN 7 31705081 missense probably damaging 1.00
R0457:Scgb2b7 UTSW 7 31704012 missense possibly damaging 0.85
R7741:Scgb2b7 UTSW 7 31705029 critical splice donor site probably null
Posted On2016-08-02