Incidental Mutation 'IGL03309:Glipr1l1'
| ID |
416506 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Glipr1l1
|
| Ensembl Gene |
ENSMUSG00000020213 |
| Gene Name |
GLI pathogenesis-related 1 like 1 |
| Synonyms |
1700011E04Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.048)
|
| Stock # |
IGL03309
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
111896094-111914415 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 111908141 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073302
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073617]
|
| AlphaFold |
Q9DAG6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073617
|
| SMART Domains |
Protein: ENSMUSP00000073302
Gene: ENSMUSG00000020213
| Domain | Start | End | E-Value | Type |
|---|
|
SCP
|
40 |
186 |
6.52e-50 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 33 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
A |
G |
3: 59,947,303 (GRCm39) |
T334A |
possibly damaging |
Het |
| Armc9 |
A |
G |
1: 86,202,155 (GRCm39) |
E771G |
possibly damaging |
Het |
| Cd207 |
G |
T |
6: 83,654,735 (GRCm39) |
T16K |
possibly damaging |
Het |
| Cd44 |
C |
T |
2: 102,644,522 (GRCm39) |
E421K |
probably damaging |
Het |
| Cfap221 |
A |
G |
1: 119,862,331 (GRCm39) |
Y584H |
probably damaging |
Het |
| Clock |
A |
G |
5: 76,379,241 (GRCm39) |
|
probably null |
Het |
| Clpx |
T |
G |
9: 65,229,974 (GRCm39) |
L474R |
probably damaging |
Het |
| Cntd1 |
T |
C |
11: 101,175,590 (GRCm39) |
V143A |
probably damaging |
Het |
| Cttnbp2 |
A |
G |
6: 18,381,035 (GRCm39) |
V877A |
probably damaging |
Het |
| Dlx6 |
G |
T |
6: 6,867,289 (GRCm39) |
M158I |
possibly damaging |
Het |
| Fank1 |
A |
G |
7: 133,463,902 (GRCm39) |
T33A |
probably damaging |
Het |
| Fbf1 |
A |
G |
11: 116,038,637 (GRCm39) |
L828P |
probably damaging |
Het |
| Fh1 |
A |
T |
1: 175,431,609 (GRCm39) |
S426T |
probably benign |
Het |
| Gabrg3 |
G |
T |
7: 56,632,433 (GRCm39) |
Q172K |
probably damaging |
Het |
| Hypk |
T |
A |
2: 121,288,673 (GRCm39) |
L113* |
probably null |
Het |
| Hypk |
G |
T |
2: 121,288,674 (GRCm39) |
L113F |
probably damaging |
Het |
| Ipo5 |
G |
A |
14: 121,157,416 (GRCm39) |
V85I |
probably benign |
Het |
| Kif1a |
A |
T |
1: 92,986,579 (GRCm39) |
Y575* |
probably null |
Het |
| Morf4l1 |
T |
A |
9: 89,985,798 (GRCm39) |
E60V |
probably benign |
Het |
| Or52ac1 |
A |
G |
7: 104,246,248 (GRCm39) |
F47L |
probably benign |
Het |
| Or6c6 |
A |
T |
10: 129,187,178 (GRCm39) |
T249S |
probably benign |
Het |
| Parp4 |
A |
T |
14: 56,825,265 (GRCm39) |
T130S |
probably benign |
Het |
| Prkd1 |
A |
G |
12: 50,435,207 (GRCm39) |
Y507H |
probably damaging |
Het |
| Psme2b |
A |
C |
11: 48,836,626 (GRCm39) |
|
probably null |
Het |
| Rbm44 |
T |
C |
1: 91,096,562 (GRCm39) |
|
probably null |
Het |
| Rngtt |
C |
A |
4: 33,339,091 (GRCm39) |
R299S |
probably damaging |
Het |
| Ros1 |
A |
G |
10: 51,994,357 (GRCm39) |
S1308P |
possibly damaging |
Het |
| Rpl3l |
A |
G |
17: 24,954,998 (GRCm39) |
K398E |
possibly damaging |
Het |
| Scube3 |
C |
T |
17: 28,383,331 (GRCm39) |
R374* |
probably null |
Het |
| Srcap |
A |
G |
7: 127,129,965 (GRCm39) |
T616A |
probably damaging |
Het |
| Stk3 |
G |
A |
15: 35,099,697 (GRCm39) |
|
probably benign |
Het |
| Tas2r124 |
A |
T |
6: 132,731,898 (GRCm39) |
D69V |
probably benign |
Het |
| Zbtb41 |
T |
A |
1: 139,359,816 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Glipr1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00467:Glipr1l1
|
APN |
10 |
111,914,286 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01660:Glipr1l1
|
APN |
10 |
111,908,184 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01893:Glipr1l1
|
APN |
10 |
111,912,074 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02576:Glipr1l1
|
APN |
10 |
111,896,224 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
P0031:Glipr1l1
|
UTSW |
10 |
111,896,292 (GRCm39) |
missense |
probably benign |
|
|
R0987:Glipr1l1
|
UTSW |
10 |
111,914,340 (GRCm39) |
missense |
probably benign |
|
|
R0992:Glipr1l1
|
UTSW |
10 |
111,898,230 (GRCm39) |
missense |
probably benign |
|
|
R2136:Glipr1l1
|
UTSW |
10 |
111,896,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2248:Glipr1l1
|
UTSW |
10 |
111,898,192 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4297:Glipr1l1
|
UTSW |
10 |
111,898,252 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4298:Glipr1l1
|
UTSW |
10 |
111,898,252 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4569:Glipr1l1
|
UTSW |
10 |
111,898,317 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Glipr1l1
|
UTSW |
10 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Glipr1l1
|
UTSW |
10 |
111,898,243 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5629:Glipr1l1
|
UTSW |
10 |
111,914,308 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6061:Glipr1l1
|
UTSW |
10 |
111,912,075 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6237:Glipr1l1
|
UTSW |
10 |
111,896,332 (GRCm39) |
nonsense |
probably null |
|
|
R6519:Glipr1l1
|
UTSW |
10 |
111,898,153 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6913:Glipr1l1
|
UTSW |
10 |
111,898,339 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7621:Glipr1l1
|
UTSW |
10 |
111,896,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8171:Glipr1l1
|
UTSW |
10 |
111,914,289 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9182:Glipr1l1
|
UTSW |
10 |
111,912,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9319:Glipr1l1
|
UTSW |
10 |
111,898,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9508:Glipr1l1
|
UTSW |
10 |
111,912,015 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0023:Glipr1l1
|
UTSW |
10 |
111,914,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Glipr1l1
|
UTSW |
10 |
111,914,295 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2016-08-02 |
Incidental Mutation