Incidental Mutation 'IGL03327:Gm17079'
ID416672
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17079
Ensembl Gene ENSMUSG00000090740
Gene Namepredicted gene 17079
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL03327
Quality Score
Status
Chromosome14
Chromosomal Location51691019-51695468 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 51692963 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 142 (T142A)
Ref Sequence ENSEMBL: ENSMUSP00000125788 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000167231]
Predicted Effect possibly damaging
Transcript: ENSMUST00000167231
AA Change: T142A

PolyPhen 2 Score 0.651 (Sensitivity: 0.87; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000125788
Gene: ENSMUSG00000090740
AA Change: T142A

DomainStartEndE-ValueType
Pfam:Takusan 57 135 1.3e-24 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A430105I19Rik T C 2: 118,761,670 N79S probably damaging Het
Adcy8 T C 15: 64,920,267 Y280C probably damaging Het
Anapc1 T C 2: 128,623,934 T1647A probably benign Het
Ano3 T C 2: 110,697,178 I562V possibly damaging Het
Ash1l C T 3: 89,023,083 P1956S probably benign Het
Cd160 C T 3: 96,805,533 probably null Het
Chd3 G T 11: 69,350,186 A1527E probably damaging Het
Clcn1 C T 6: 42,311,219 T797I probably benign Het
Cntnap3 G A 13: 64,887,768 Q44* probably null Het
Cntnap4 A G 8: 112,773,576 D500G probably benign Het
Col6a6 T C 9: 105,767,234 D1285G possibly damaging Het
Cr2 A T 1: 195,169,759 V94E probably damaging Het
Dcaf1 T C 9: 106,858,624 S924P possibly damaging Het
Eif5b T C 1: 38,041,691 probably benign Het
Fat1 A C 8: 44,950,468 K85N probably damaging Het
Fnip2 T C 3: 79,518,081 E69G probably damaging Het
Fzr1 T C 10: 81,369,184 T300A probably benign Het
Galc A G 12: 98,207,476 probably benign Het
Hibch G A 1: 52,920,380 probably benign Het
Hmmr A G 11: 40,715,415 C243R probably damaging Het
Il25 T C 14: 54,935,360 probably benign Het
Kif5b G A 18: 6,222,767 R355W probably damaging Het
Kifc3 C T 8: 95,108,432 D242N probably damaging Het
Lig1 T G 7: 13,303,855 I677S probably damaging Het
Lrig1 G T 6: 94,606,123 A1004E probably benign Het
Nras A G 3: 103,059,024 T35A probably damaging Het
Nt5c1b C T 12: 10,374,861 Q136* probably null Het
Olfr1046 C T 2: 86,217,274 W145* probably null Het
Olfr1278 A T 2: 111,292,462 N65Y probably damaging Het
Olfr815 T G 10: 129,902,582 I43L possibly damaging Het
Plcb3 A G 19: 6,955,052 F1080L probably benign Het
Plpp2 T C 10: 79,530,984 probably null Het
Ptpre G A 7: 135,672,822 probably null Het
Scn3a G A 2: 65,536,672 A2V probably damaging Het
Sh3bp4 C A 1: 89,144,163 Y244* probably null Het
Trip11 A T 12: 101,883,418 N1462K possibly damaging Het
Ttc21b T C 2: 66,237,848 D278G possibly damaging Het
Virma A G 4: 11,518,984 T694A probably benign Het
Wdr35 T C 12: 8,978,694 probably benign Het
Xdh T C 17: 73,916,792 E535G probably benign Het
Other mutations in Gm17079
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02368:Gm17079 APN 14 51693067 missense possibly damaging 0.95
IGL03039:Gm17079 APN 14 51693061 missense probably damaging 1.00
IGL03346:Gm17079 APN 14 51692963 missense possibly damaging 0.65
R1487:Gm17079 UTSW 14 51693085 splice site probably null
R6612:Gm17079 UTSW 14 51694375 missense probably damaging 1.00
R6612:Gm17079 UTSW 14 51694376 missense possibly damaging 0.85
R7028:Gm17079 UTSW 14 51693037 missense
Posted On2016-08-02