Incidental Mutation 'IGL03331:Dppa2'
ID416886
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Dppa2
Ensembl Gene ENSMUSG00000072419
Gene Namedevelopmental pluripotency associated 2
Synonyms2410088E07Rik, ECAT15-2
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.100) question?
Stock #IGL03331
Quality Score
Status
Chromosome16
Chromosomal Location48303908-48319723 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 48313879 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000156143 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000097175] [ENSMUST00000232448]
Predicted Effect probably benign
Transcript: ENSMUST00000097175
SMART Domains Protein: ENSMUSP00000110183
Gene: ENSMUSG00000072419

DomainStartEndE-ValueType
SAP 85 119 2.86e-1 SMART
Pfam:Dppa2_A 124 206 2.3e-34 PFAM
Pfam:DCR 211 277 4.7e-40 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000232448
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akap11 C A 14: 78,513,865 D361Y probably damaging Het
Arhgap10 T C 8: 77,420,082 N231S probably damaging Het
Asb15 A T 6: 24,556,524 D6V possibly damaging Het
C1qb G A 4: 136,880,293 A253V probably damaging Het
Ccdc178 G T 18: 21,811,583 probably null Het
Chst15 A G 7: 132,262,713 L387P probably damaging Het
Clca3b T A 3: 144,827,963 E550D probably benign Het
Dnah5 A G 15: 28,419,940 K3795E probably damaging Het
Epb41l5 T C 1: 119,617,419 Y220C probably damaging Het
Fkbpl C T 17: 34,645,687 T143I probably damaging Het
Gbe1 T G 16: 70,433,578 Y155D probably damaging Het
Gm1979 T C 5: 26,002,010 K69R probably damaging Het
Gna14 G A 19: 16,609,468 V336M probably damaging Het
Gpr37 A G 6: 25,669,729 V372A probably benign Het
Herc2 C A 7: 56,135,267 probably benign Het
Hist1h2bk T C 13: 22,036,273 probably benign Het
Krt20 T C 11: 99,435,430 probably null Het
Lman1 T C 18: 65,993,204 T284A probably benign Het
Matn2 A T 15: 34,345,357 D170V probably damaging Het
Morc1 C A 16: 48,612,368 probably benign Het
Necap1 T A 6: 122,880,417 S34T probably benign Het
Nt5c3b T C 11: 100,436,215 Y85C probably damaging Het
Olfr1454 T A 19: 13,063,867 L152H probably damaging Het
Olfr720 C A 14: 14,176,017 A22S probably benign Het
Papln A G 12: 83,783,661 M1016V probably benign Het
Pld1 T C 3: 28,085,845 F605L probably damaging Het
Rbms2 T A 10: 128,133,635 probably benign Het
Rps6kb1 A T 11: 86,532,830 V108E probably damaging Het
Scap T C 9: 110,380,236 probably null Het
Serpina1f T C 12: 103,690,891 I307M probably benign Het
Tchh A G 3: 93,443,418 D55G probably damaging Het
Tnfaip3 G T 10: 19,011,601 Q59K possibly damaging Het
Vcan A G 13: 89,661,932 C2287R probably damaging Het
Vmn2r6 T C 3: 64,538,007 N766D probably damaging Het
Other mutations in Dppa2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00980:Dppa2 APN 16 48311686 missense possibly damaging 0.93
IGL01365:Dppa2 APN 16 48313913 missense possibly damaging 0.83
IGL03279:Dppa2 APN 16 48311665 missense possibly damaging 0.91
R0048:Dppa2 UTSW 16 48317398 missense probably benign 0.02
R0549:Dppa2 UTSW 16 48318671 missense probably benign 0.20
R1321:Dppa2 UTSW 16 48311636 missense possibly damaging 0.72
R1826:Dppa2 UTSW 16 48317348 missense probably damaging 0.98
R4553:Dppa2 UTSW 16 48310514 missense possibly damaging 0.59
R5124:Dppa2 UTSW 16 48311623 missense probably damaging 0.98
R5144:Dppa2 UTSW 16 48317303 missense probably damaging 0.98
R5983:Dppa2 UTSW 16 48315841 missense probably benign 0.03
R6638:Dppa2 UTSW 16 48314160 missense possibly damaging 0.86
R7060:Dppa2 UTSW 16 48315713 missense probably benign 0.02
Posted On2016-08-02