Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03333:Gm6619'

416935

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm6619

Ensembl Gene

ENSMUSG00000095577

Gene Name

predicted gene 6619

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.090) question?

Stock #

IGL03333

Quality Score

Status

Chromosome

Chromosomal Location

131463369-131468456 bp(+) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

G to A at 131467471 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000074539 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000075020] [ENSMUST00000159229]

AlphaFold

F6URP1

Predicted Effect

probably benign
Transcript: ENSMUST00000075020

SMART Domains

Protein: ENSMUSP00000074539
Gene: ENSMUSG00000094113

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	100	116	N/A	INTRINSIC
low complexity region	118	166	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000159229
AA Change: R112H

SMART Domains

Protein: ENSMUSP00000123949
Gene: ENSMUSG00000095577
AA Change: R112H

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	99	166	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arhgap39	T	C	15: 76,610,932 (GRCm39)	M893V	probably benign	Het
Ccdc185	C	A	1: 182,576,398 (GRCm39)	G97V	probably damaging	Het
Cep170	T	C	1: 176,597,092 (GRCm39)	T422A	possibly damaging	Het
Ckap2l	A	C	2: 129,138,228 (GRCm39)		probably null	Het
Cpa3	A	G	3: 20,269,992 (GRCm39)	Y411H	possibly damaging	Het
Dnah2	C	A	11: 69,385,949 (GRCm39)	R1011L	probably damaging	Het
Efnb2	T	A	8: 8,689,275 (GRCm39)	K30*	probably null	Het
Ep400	C	T	5: 110,851,432 (GRCm39)	R1350H	unknown	Het
Epha6	T	C	16: 59,503,051 (GRCm39)	D952G	probably damaging	Het
Exoc7	C	A	11: 116,191,987 (GRCm39)	V195L	probably benign	Het
Fbxw8	T	C	5: 118,233,660 (GRCm39)	M324V	possibly damaging	Het
Fchsd2	T	C	7: 100,847,703 (GRCm39)	S198P	probably damaging	Het
Gcdh	T	C	8: 85,617,700 (GRCm39)	T202A	probably benign	Het
Itpr1	A	T	6: 108,357,871 (GRCm39)		probably benign	Het
Kif2c	A	C	4: 117,037,833 (GRCm39)	V31G	possibly damaging	Het
Kpna7	T	C	5: 144,942,765 (GRCm39)	I74V	possibly damaging	Het
Lvrn	G	A	18: 46,997,731 (GRCm39)		probably benign	Het
Man2b2	T	A	5: 36,973,483 (GRCm39)	I499F	probably damaging	Het
Mmd2	G	T	5: 142,553,693 (GRCm39)		probably benign	Het
Or11h7	C	T	14: 50,890,855 (GRCm39)	Q54*	probably null	Het
Or2r11	T	C	6: 42,437,773 (GRCm39)	Y60C	probably damaging	Het
Or6b1	T	A	6: 42,815,637 (GRCm39)	I274N	possibly damaging	Het
Or8g2b	T	A	9: 39,751,308 (GRCm39)	Y193N	probably damaging	Het
Parp14	A	G	16: 35,661,800 (GRCm39)	S1412P	probably benign	Het
Prr30	A	T	14: 101,435,827 (GRCm39)	V245E	possibly damaging	Het
Ros1	T	A	10: 52,031,267 (GRCm39)	D458V	probably damaging	Het
Sec22c	A	G	9: 121,517,284 (GRCm39)	L138P	probably damaging	Het
Sema6d	C	A	2: 124,506,290 (GRCm39)	H699Q	possibly damaging	Het
Spata17	A	T	1: 186,872,667 (GRCm39)	M1K	probably null	Het
Tpr	T	A	1: 150,302,718 (GRCm39)	D1331E	probably benign	Het
Ttc4	A	G	4: 106,533,828 (GRCm39)	Y120H	probably benign	Het
Tubgcp4	A	G	2: 121,026,654 (GRCm39)		probably null	Het
Usp19	T	A	9: 108,371,348 (GRCm39)	M285K	probably benign	Het
Vmn1r222	A	T	13: 23,417,177 (GRCm39)	F12Y	probably benign	Het
Vmn2r72	T	C	7: 85,400,075 (GRCm39)	K325E	probably benign	Het
Vps33b	T	C	7: 79,923,973 (GRCm39)		probably benign	Het
Zfp784	C	T	7: 5,039,351 (GRCm39)		probably benign	Het

Other mutations in Gm6619

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01099:Gm6619	APN	6	131,467,393 (GRCm39)	missense	possibly damaging	0.66
IGL02438:Gm6619	APN	6	131,467,398 (GRCm39)	missense	possibly damaging	0.83
IGL02511:Gm6619	APN	6	131,467,330 (GRCm39)	missense	possibly damaging	0.49
R0744:Gm6619	UTSW	6	131,467,297 (GRCm39)	missense	probably damaging	0.97
R2150:Gm6619	UTSW	6	131,466,021 (GRCm39)	missense	probably benign	0.03
R5817:Gm6619	UTSW	6	131,463,400 (GRCm39)	missense	unknown
R6869:Gm6619	UTSW	6	131,463,401 (GRCm39)	missense	unknown
R7439:Gm6619	UTSW	6	131,467,354 (GRCm39)	missense	possibly damaging	0.66
R7441:Gm6619	UTSW	6	131,467,354 (GRCm39)	missense	possibly damaging	0.66
R9413:Gm6619	UTSW	6	131,468,370 (GRCm39)	missense	unknown

Posted On

2016-08-02