Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03334:Vmn2r35'

List [record 1 of 1]

416947

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r35

Ensembl Gene

ENSMUSG00000096399

Gene Name

vomeronasal 2, receptor 35

Synonyms

EG625353

Accession Numbers

Is this an essential gene?

Not available question?

Stock #

IGL03334

Quality Score

Status

Chromosome

Chromosomal Location

7786151-7819867 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 7786494 bp

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 748 (Y748F)

Ref Sequence

ENSEMBL: ENSMUSP00000133007 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169683]

Predicted Effect

probably damaging
Transcript: ENSMUST00000169683
AA Change: Y748F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000133007
Gene: ENSMUSG00000096399
AA Change: Y748F

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	1.8e-32	PFAM
Pfam:NCD3G	512	565	1.2e-18	PFAM
Pfam:7tm_3	595	833	2.4e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9930111J21Rik1	A	G	11: 48,947,475	F762L	probably benign	Het
A430078G23Rik	A	T	8: 3,388,023	I286F	probably benign	Het
Angpt1	T	A	15: 42,496,412	E208V	possibly damaging	Het
Arhgef5	T	C	6: 43,274,000	S562P	possibly damaging	Het
Asb6	T	C	2: 30,824,484	T205A	probably benign	Het
B4galnt4	G	A	7: 141,067,441		probably null	Het
Clca4a	A	T	3: 144,953,866	M743K	probably benign	Het
Col14a1	T	C	15: 55,448,821		probably benign	Het
Col27a1	A	T	4: 63,314,722	Y359F	probably damaging	Het
Dhcr7	T	A	7: 143,840,497	V125D	possibly damaging	Het
Ercc3	T	C	18: 32,240,837		probably null	Het
Fnbp1l	A	G	3: 122,557,949	V315A	probably benign	Het
Gm17174	T	A	14: 51,591,963	R48*	probably null	Het
Golga4	C	T	9: 118,537,233		probably benign	Het
Grin1	C	T	2: 25,298,393		probably null	Het
Ifi203	T	A	1: 173,937,835	K58*	probably null	Het
Ighv2-9-1	A	G	12: 113,769,923	S93P	probably benign	Het
Il27ra	A	G	8: 84,031,122	V594A	probably benign	Het
Krr1	T	G	10: 111,980,054	S275R	probably benign	Het
Lars	T	C	18: 42,221,506	D792G	probably benign	Het
Myo1f	G	A	17: 33,598,194	R737H	probably damaging	Het
Nebl	T	A	2: 17,413,711	H292L	probably damaging	Het
Nell1	C	A	7: 50,062,611		probably null	Het
Nktr	T	C	9: 121,748,176	F412L	probably benign	Het
Nlrp3	T	A	11: 59,549,016	I473N	probably damaging	Het
Olfr338	T	C	2: 36,377,051	Y92H	possibly damaging	Het
Phf3	A	G	1: 30,805,729	V1383A	probably damaging	Het
Prss48	T	C	3: 85,997,318	E191G	probably damaging	Het
Psg25	T	A	7: 18,529,774	L41F	probably benign	Het
Sema3b	A	G	9: 107,604,077	L78P	probably damaging	Het
Spen	G	T	4: 141,469,969	N3496K	probably damaging	Het
Tbk1	A	T	10: 121,584,199	H28Q	possibly damaging	Het
Trpv3	T	A	11: 73,281,665		probably benign	Het
Vmn1r218	T	C	13: 23,136,618	L45P	probably damaging	Het
Vps18	C	T	2: 119,297,482	R929W	probably damaging	Het
Xpnpep1	T	C	19: 53,010,146	K224E	probably damaging	Het
Zbed5	T	A	5: 129,902,355	F382I	possibly damaging	Het

Other mutations in Vmn2r35

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01875:Vmn2r35	APN	7	7816773	splice site	probably benign
R1858:Vmn2r35	UTSW	7	7816806	missense	possibly damaging	0.46
R5505:Vmn2r35	UTSW	7	7786480	missense	probably damaging	1.00
R6150:Vmn2r35	UTSW	7	7786556	missense	probably damaging	1.00
R6211:Vmn2r35	UTSW	7	7786528	missense	probably damaging	0.99
R7439:Vmn2r35	UTSW	7	7817014	missense	probably damaging	1.00
R8399:Vmn2r35	UTSW	7	7816898	missense	probably benign	0.00

Posted On

2016-08-02