Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03339:Taar7d'

417137

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Taar7d

Ensembl Gene

ENSMUSG00000095569

Gene Name

trace amine-associated receptor 7D

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.143) question?

Stock #

IGL03339

Quality Score

Status

Chromosome

Chromosomal Location

24027222-24028298 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 24027306 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Arginine at position 29 (C29R)

Ref Sequence

ENSEMBL: ENSMUSP00000090327 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092657]

AlphaFold

Q5QD10

Predicted Effect

possibly damaging
Transcript: ENSMUST00000092657
AA Change: C29R

PolyPhen 2 Score 0.919 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000090327
Gene: ENSMUSG00000095569
AA Change: C29R

Domain	Start	End	E-Value	Type
Pfam:7TM_GPCR_Srx	56	261	6.5e-9	PFAM
Pfam:7TM_GPCR_Srsx	58	341	2e-10	PFAM
Pfam:7tm_1	64	326	1.5e-57	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
6820408C15Rik	A	G	2: 152,442,456	E323G	probably damaging	Het
A4gnt	T	C	9: 99,620,548	S254P	probably damaging	Het
Actn4	A	G	7: 28,901,982	L447P	probably damaging	Het
Agbl2	C	A	2: 90,797,563	S237R	probably damaging	Het
Apc	G	A	18: 34,298,474	D309N	probably damaging	Het
Arhgef3	A	G	14: 27,401,857	M492V	probably damaging	Het
Atp10b	T	A	11: 43,230,615	M1035K	probably null	Het
Cfap69	T	A	5: 5,586,436		probably benign	Het
Ctf1	A	G	7: 127,713,994	N24S	probably benign	Het
Cx3cr1	T	A	9: 120,051,437	K300*	probably null	Het
Ddx25	A	T	9: 35,542,003	Y484N	probably damaging	Het
Eif4g1	A	G	16: 20,680,984	E506G	possibly damaging	Het
Ficd	G	T	5: 113,738,739	R325L	probably benign	Het
G6pc2	A	G	2: 69,220,895		probably benign	Het
Gm11168	C	A	9: 3,004,767	P103T	probably benign	Het
Hbb-y	A	T	7: 103,852,769	H98Q	probably damaging	Het
Hmcn1	A	G	1: 150,701,969	S2014P	probably benign	Het
Hoxc5	T	C	15: 103,014,136	Y19H	probably damaging	Het
Igfbpl1	A	G	4: 45,813,555		probably benign	Het
Ighg2c	A	C	12: 113,287,994	V171G	unknown	Het
Kctd13	A	G	7: 126,945,018	D296G	probably benign	Het
Mfsd2b	A	C	12: 4,874,335	M1R	probably null	Het
Nipbl	A	G	15: 8,350,876	S811P	probably benign	Het
Olfr118	G	A	17: 37,672,557	C178Y	possibly damaging	Het
Olfr119	G	T	17: 37,700,791	M40I	probably damaging	Het
Olfr1484	T	G	19: 13,586,075	M257R	probably damaging	Het
Olfr569	G	A	7: 102,887,782	R124C	probably benign	Het
Pcolce2	T	C	9: 95,678,340		probably benign	Het
Pik3c2a	G	T	7: 116,418,021	T167K	possibly damaging	Het
Ppp1r18	A	G	17: 35,868,046	D271G	probably benign	Het
Rnf213	T	C	11: 119,443,004	I3013T	probably damaging	Het
Rock1	A	T	18: 10,097,493	M765K	probably benign	Het
Sec16a	T	C	2: 26,435,933	Y1244C	probably benign	Het
Tmem56	C	T	3: 121,228,840		probably benign	Het
Ttn	A	C	2: 76,741,920	F26210V	probably damaging	Het
Ube2b	A	T	11: 51,986,707	V145D	probably damaging	Het
Vmn1r219	T	G	13: 23,163,410	S256R	possibly damaging	Het

Other mutations in Taar7d

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01719:Taar7d	APN	10	24027967	missense	probably benign	0.00
IGL02070:Taar7d	APN	10	24028254	missense	probably benign	0.00
IGL02280:Taar7d	APN	10	24028108	missense	probably damaging	1.00
IGL02525:Taar7d	APN	10	24028096	missense	possibly damaging	0.80
IGL03115:Taar7d	APN	10	24027641	missense	probably benign	0.10
R1509:Taar7d	UTSW	10	24028204	missense	probably damaging	0.99
R1826:Taar7d	UTSW	10	24027576	missense	probably damaging	0.99
R2016:Taar7d	UTSW	10	24027744	missense	probably benign	0.11
R2051:Taar7d	UTSW	10	24028006	missense	probably benign	0.00
R6075:Taar7d	UTSW	10	24027660	missense	probably benign	0.21
R6541:Taar7d	UTSW	10	24028231	missense	probably benign	0.01
R8165:Taar7d	UTSW	10	24027597	missense	probably benign	0.07
R9222:Taar7d	UTSW	10	24028226	missense	probably benign	0.08
R9456:Taar7d	UTSW	10	24027389	missense	probably benign
R9481:Taar7d	UTSW	10	24027841	missense	probably benign	0.00
X0067:Taar7d	UTSW	10	24028008	missense	probably damaging	1.00

Posted On

2016-08-02