Incidental Mutation 'IGL03340:Sun3'
ID 417208
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sun3
Ensembl Gene ENSMUSG00000040985
Gene Name Sad1 and UNC84 domain containing 3
Synonyms Sunc1, D630047F21Rik
Accession Numbers
Essential gene? Probably non essential (E-score: 0.052) question?
Stock # IGL03340
Quality Score
Status
Chromosome 11
Chromosomal Location 8966054-8998991 bp(-) (GRCm39)
Type of Mutation splice site
DNA Base Change (assembly) A to C at 8973285 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000099973 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000043377] [ENSMUST00000102909]
AlphaFold Q5SS91
Predicted Effect probably benign
Transcript: ENSMUST00000043377
SMART Domains Protein: ENSMUSP00000045199
Gene: ENSMUSG00000040985

DomainStartEndE-ValueType
transmembrane domain 7 29 N/A INTRINSIC
Pfam:Sad1_UNC 182 316 3.4e-48 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000102909
SMART Domains Protein: ENSMUSP00000099973
Gene: ENSMUSG00000040985

DomainStartEndE-ValueType
Pfam:Sad1_UNC 122 256 3.2e-48 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700097O09Rik A G 12: 55,126,786 (GRCm39) L26P probably benign Het
Aff1 A T 5: 103,931,670 (GRCm39) H104L possibly damaging Het
Apon T C 10: 128,090,847 (GRCm39) I175T probably benign Het
C2cd6 A C 1: 59,115,830 (GRCm39) F168V probably benign Het
Cgn C T 3: 94,685,405 (GRCm39) probably benign Het
Cramp1 G A 17: 25,192,516 (GRCm39) P956L probably damaging Het
Cyp2e1 G A 7: 140,344,767 (GRCm39) V78M probably damaging Het
Cyp4b1 G A 4: 115,499,076 (GRCm39) P97S probably damaging Het
Fads2 G T 19: 10,069,136 (GRCm39) P96Q possibly damaging Het
Fcer2a T C 8: 3,738,310 (GRCm39) D120G possibly damaging Het
Fhip1b A G 7: 105,038,517 (GRCm39) S241P probably damaging Het
Gm21972 G T 1: 86,061,450 (GRCm39) A887S probably damaging Het
Grk6 A G 13: 55,601,003 (GRCm39) D295G probably damaging Het
Herc2 T A 7: 55,740,668 (GRCm39) V270D possibly damaging Het
Kcnk2 T A 1: 189,027,878 (GRCm39) I126F possibly damaging Het
Kifap3 T G 1: 163,656,718 (GRCm39) V346G possibly damaging Het
Kpna1 T A 16: 35,820,616 (GRCm39) N20K probably damaging Het
Krt33b A G 11: 99,916,298 (GRCm39) probably benign Het
Krtap9-5 T C 11: 99,839,427 (GRCm39) C43R possibly damaging Het
Lars1 G A 18: 42,361,715 (GRCm39) probably benign Het
Lifr T C 15: 7,207,417 (GRCm39) W540R probably benign Het
Lrp1b A G 2: 41,358,981 (GRCm39) S631P probably damaging Het
Mbd1 G T 18: 74,407,553 (GRCm39) R111L probably benign Het
Meltf C T 16: 31,711,602 (GRCm39) T576M probably damaging Het
Mmp20 G A 9: 7,643,995 (GRCm39) G228S probably damaging Het
Mob4 A G 1: 55,175,867 (GRCm39) D37G possibly damaging Het
Msr1 T C 8: 40,073,048 (GRCm39) K234E possibly damaging Het
Myof A G 19: 37,899,607 (GRCm39) V1764A probably damaging Het
Naaladl1 A G 19: 6,156,229 (GRCm39) Y105C possibly damaging Het
Nisch A G 14: 30,895,101 (GRCm39) V1065A probably damaging Het
Npas4 A T 19: 5,035,094 (GRCm39) probably benign Het
Or4c124 T C 2: 89,156,039 (GRCm39) T162A possibly damaging Het
Pdss2 A G 10: 43,269,997 (GRCm39) D280G probably benign Het
Plk3 A G 4: 116,990,125 (GRCm39) I182T probably damaging Het
Ppm1k A G 6: 57,487,711 (GRCm39) W371R probably damaging Het
Samm50 T C 15: 84,082,864 (GRCm39) probably null Het
Scaper G T 9: 55,510,116 (GRCm39) T640K possibly damaging Het
Svep1 T A 4: 58,111,451 (GRCm39) K1056M possibly damaging Het
Tgs1 C A 4: 3,604,813 (GRCm39) P745Q probably benign Het
Tomm20l A T 12: 71,164,388 (GRCm39) probably benign Het
Usp38 A C 8: 81,738,905 (GRCm39) L237V probably damaging Het
Vmn1r210 T C 13: 23,011,644 (GRCm39) Y214C probably benign Het
Zan G A 5: 137,426,136 (GRCm39) P2547S unknown Het
Other mutations in Sun3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01290:Sun3 APN 11 8,973,341 (GRCm39) missense possibly damaging 0.91
IGL01473:Sun3 APN 11 8,979,394 (GRCm39) missense probably benign 0.00
IGL01578:Sun3 APN 11 8,979,436 (GRCm39) missense probably damaging 0.98
R1944:Sun3 UTSW 11 8,988,296 (GRCm39) missense probably benign 0.00
R1945:Sun3 UTSW 11 8,988,296 (GRCm39) missense probably benign 0.00
R2233:Sun3 UTSW 11 8,973,371 (GRCm39) nonsense probably null
R4356:Sun3 UTSW 11 8,966,328 (GRCm39) missense probably damaging 1.00
R4784:Sun3 UTSW 11 8,988,266 (GRCm39) missense probably benign 0.00
R4785:Sun3 UTSW 11 8,988,266 (GRCm39) missense probably benign 0.00
R4975:Sun3 UTSW 11 8,988,311 (GRCm39) nonsense probably null
R5022:Sun3 UTSW 11 8,988,314 (GRCm39) missense probably damaging 0.96
R5134:Sun3 UTSW 11 8,988,287 (GRCm39) missense probably benign 0.04
R5163:Sun3 UTSW 11 8,973,295 (GRCm39) missense possibly damaging 0.89
R5358:Sun3 UTSW 11 8,981,496 (GRCm39) missense possibly damaging 0.90
R5668:Sun3 UTSW 11 8,981,433 (GRCm39) critical splice donor site probably null
R6621:Sun3 UTSW 11 8,966,242 (GRCm39) missense probably damaging 1.00
R7442:Sun3 UTSW 11 8,981,445 (GRCm39) missense possibly damaging 0.75
R8022:Sun3 UTSW 11 8,973,376 (GRCm39) missense probably damaging 1.00
R8134:Sun3 UTSW 11 8,979,346 (GRCm39) missense probably benign 0.00
R9130:Sun3 UTSW 11 8,968,170 (GRCm39) missense probably benign 0.13
R9454:Sun3 UTSW 11 8,988,281 (GRCm39) missense probably benign
Posted On 2016-08-02