Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03343:Vmn2r105'

417319

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r105

Ensembl Gene

ENSMUSG00000091670

Gene Name

vomeronasal 2, receptor 105

Synonyms

EG627743

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL03343

Quality Score

Status

Chromosome

Chromosomal Location

20208230-20234872 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 20226369 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Stop codon at position 456 (W456*)

Ref Sequence

ENSEMBL: ENSMUSP00000129762 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000167382]

AlphaFold

E9Q3A5

Predicted Effect

probably null
Transcript: ENSMUST00000167382
AA Change: W456*

SMART Domains

Protein: ENSMUSP00000129762
Gene: ENSMUSG00000091670
AA Change: W456*

Domain	Start	End	E-Value	Type
Pfam:ANF_receptor	85	469	6.5e-42	PFAM
Pfam:NCD3G	512	565	3.2e-21	PFAM
Pfam:7tm_3	598	833	2.5e-51	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
5430419D17Rik	T	A	7: 131,246,691	I858N	probably damaging	Het
Adamts17	A	G	7: 67,075,316	H795R	probably damaging	Het
Adgrl2	A	T	3: 148,859,380	I188K	probably damaging	Het
Adgrv1	A	G	13: 81,283,388	Y5974H	probably damaging	Het
Angpt4	A	G	2: 151,936,703	T336A	probably damaging	Het
Arhgap30	C	A	1: 171,409,094	T1012N	probably damaging	Het
Asl	A	T	5: 130,012,067	Y178N	probably damaging	Het
Brd1	C	A	15: 88,707,251	L714F	possibly damaging	Het
Ccdc129	T	G	6: 55,968,584	D763E	probably damaging	Het
Ccdc47	A	G	11: 106,204,962	S303P	probably damaging	Het
Cdk16	A	G	X: 20,695,759	K264E	probably damaging	Het
Cenpc1	A	T	5: 86,016,322	F813L	probably damaging	Het
Cfp	A	C	X: 20,928,009	F291C	possibly damaging	Het
Chordc1	T	G	9: 18,312,466	F276V	probably damaging	Het
Clic4	C	T	4: 135,218,578	R176H	possibly damaging	Het
Dusp27	T	C	1: 166,099,448	D865G	probably benign	Het
Fcer1a	T	G	1: 173,225,473	N52T	possibly damaging	Het
Fndc7	A	T	3: 108,867,308	C545S	probably damaging	Het
Frem2	T	C	3: 53,652,253	D1611G	probably damaging	Het
Fryl	G	A	5: 73,076,695	P1496S	probably benign	Het
Gga3	A	T	11: 115,592,486	N82K	probably damaging	Het
Gm43638	G	A	5: 87,460,625	P452S	possibly damaging	Het
Gpn1	T	C	5: 31,504,965	S244P	probably damaging	Het
Hspa12a	T	C	19: 58,799,396	S665G	probably benign	Het
Htt	A	G	5: 34,826,041	I995V	probably benign	Het
Iars	A	T	13: 49,724,747	I916L	probably benign	Het
Ice1	C	A	13: 70,602,929	L1679F	probably damaging	Het
Inpp1	A	T	1: 52,799,327	D54E	probably damaging	Het
Irf2bpl	T	C	12: 86,882,939	E320G	possibly damaging	Het
Kcnn2	T	C	18: 45,676,959	V421A	probably damaging	Het
Micu2	A	G	14: 57,917,311	V419A	probably benign	Het
Nek9	C	T	12: 85,303,609	C897Y	probably damaging	Het
Ofcc1	A	C	13: 40,072,664	H797Q	probably benign	Het
Olfr1024	T	C	2: 85,904,941	T38A	probably benign	Het
Olfr109	G	A	17: 37,466,409	D68N	probably damaging	Het
Olfr1388	C	A	11: 49,444,243	H131N	probably damaging	Het
Olfr822	T	G	10: 130,075,256	L282R	probably damaging	Het
Pakap	C	T	4: 57,688,502	T115M	probably damaging	Het
Papss1	G	A	3: 131,583,189	G151S	probably benign	Het
Plxnb1	A	G	9: 109,114,712	T1956A	probably damaging	Het
Pomt1	A	G	2: 32,253,712		probably benign	Het
Ppfibp2	T	A	7: 107,737,919	Y570*	probably null	Het
Ppp1r9a	A	G	6: 5,046,015	E493G	probably damaging	Het
Ptk2b	A	G	14: 66,169,421	F621L	probably benign	Het
Ptpn13	G	T	5: 103,554,950	D1261Y	possibly damaging	Het
Ptprd	C	T	4: 76,059,729	G181D	probably damaging	Het
Rabgap1l	T	C	1: 160,443,283	T645A	probably benign	Het
Slc2a7	T	C	4: 150,168,340	I479T	probably damaging	Het
Smc3	A	G	19: 53,613,842	N40S	probably damaging	Het
Spata31	A	T	13: 64,919,773	D83V	probably benign	Het
Sptb	C	T	12: 76,583,556		probably benign	Het
Ssc4d	A	T	5: 135,961,174	C493*	probably null	Het
Ubr2	C	A	17: 46,951,918	V1256L	probably benign	Het
Ubr3	T	C	2: 69,973,146		probably benign	Het
Vmn2r24	T	A	6: 123,816,111	I799N	probably damaging	Het
Vps13b	G	A	15: 35,917,170	G3720D	possibly damaging	Het

Other mutations in Vmn2r105

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01433:Vmn2r105	APN	17	20228555	missense	probably benign	0.01
IGL01909:Vmn2r105	APN	17	20224656	missense	probably damaging	1.00
IGL01925:Vmn2r105	APN	17	20208711	missense	possibly damaging	0.94
IGL02021:Vmn2r105	APN	17	20227895	missense	possibly damaging	0.49
IGL02828:Vmn2r105	APN	17	20209083	missense	possibly damaging	0.80
IGL02838:Vmn2r105	APN	17	20227585	missense	probably damaging	1.00
R0096:Vmn2r105	UTSW	17	20227479	missense	possibly damaging	0.49
R0096:Vmn2r105	UTSW	17	20227479	missense	possibly damaging	0.49
R0212:Vmn2r105	UTSW	17	20208565	missense	possibly damaging	0.90
R0268:Vmn2r105	UTSW	17	20208676	missense	probably benign	0.18
R0271:Vmn2r105	UTSW	17	20234703	missense	probably damaging	0.96
R0613:Vmn2r105	UTSW	17	20208316	missense	probably damaging	1.00
R0765:Vmn2r105	UTSW	17	20227711	missense	probably benign	0.20
R0765:Vmn2r105	UTSW	17	20227857	missense	probably damaging	0.98
R1162:Vmn2r105	UTSW	17	20227711	missense	probably benign	0.20
R1263:Vmn2r105	UTSW	17	20208322	missense	probably damaging	1.00
R1363:Vmn2r105	UTSW	17	20208670	missense	probably benign	0.00
R1464:Vmn2r105	UTSW	17	20228742	splice site	probably benign
R2029:Vmn2r105	UTSW	17	20224578	missense	probably damaging	0.99
R2420:Vmn2r105	UTSW	17	20227835	missense	probably benign	0.15
R2421:Vmn2r105	UTSW	17	20227835	missense	probably benign	0.15
R2422:Vmn2r105	UTSW	17	20227835	missense	probably benign	0.15
R2570:Vmn2r105	UTSW	17	20227323	missense	probably damaging	1.00
R3847:Vmn2r105	UTSW	17	20208690	missense	possibly damaging	0.85
R3848:Vmn2r105	UTSW	17	20208690	missense	possibly damaging	0.85
R4030:Vmn2r105	UTSW	17	20208754	missense	probably damaging	0.99
R4275:Vmn2r105	UTSW	17	20228640	missense	probably damaging	1.00
R4551:Vmn2r105	UTSW	17	20226351	missense	probably benign
R4801:Vmn2r105	UTSW	17	20227294	missense	probably benign	0.00
R4802:Vmn2r105	UTSW	17	20227294	missense	probably benign	0.00
R4816:Vmn2r105	UTSW	17	20208691	missense	probably benign	0.27
R4929:Vmn2r105	UTSW	17	20228018	missense	probably benign	0.44
R5022:Vmn2r105	UTSW	17	20208414	missense	probably damaging	0.99
R5475:Vmn2r105	UTSW	17	20234782	missense	probably benign
R5576:Vmn2r105	UTSW	17	20224574	critical splice donor site	probably null
R5795:Vmn2r105	UTSW	17	20228736	missense	probably benign	0.00
R5895:Vmn2r105	UTSW	17	20228667	missense	probably benign	0.10
R6017:Vmn2r105	UTSW	17	20208627	missense	probably damaging	0.97
R6210:Vmn2r105	UTSW	17	20228496	missense	probably damaging	1.00
R6491:Vmn2r105	UTSW	17	20227730	nonsense	probably null
R6542:Vmn2r105	UTSW	17	20228541	missense	probably benign	0.03
R6729:Vmn2r105	UTSW	17	20208343	missense	probably damaging	0.99
R7020:Vmn2r105	UTSW	17	20209074	missense	probably damaging	1.00
R7033:Vmn2r105	UTSW	17	20208612	missense	probably damaging	0.97
R7488:Vmn2r105	UTSW	17	20208783	missense	probably damaging	1.00
R7491:Vmn2r105	UTSW	17	20228565	missense	probably benign	0.02
R7555:Vmn2r105	UTSW	17	20227675	missense	probably damaging	0.98
R7863:Vmn2r105	UTSW	17	20208675	missense	probably benign	0.18
R8137:Vmn2r105	UTSW	17	20234704	missense	probably benign	0.02
R8166:Vmn2r105	UTSW	17	20208642	missense	probably benign	0.07
R8186:Vmn2r105	UTSW	17	20224618	nonsense	probably null
R8214:Vmn2r105	UTSW	17	20228513	missense	probably benign	0.02
R8497:Vmn2r105	UTSW	17	20234872	start codon destroyed	probably null	0.75
R8850:Vmn2r105	UTSW	17	20208610	missense	probably damaging	1.00
R8880:Vmn2r105	UTSW	17	20208967	missense	probably damaging	0.99
R9272:Vmn2r105	UTSW	17	20227423	missense	probably damaging	1.00
R9506:Vmn2r105	UTSW	17	20209142	missense	probably benign	0.00
R9549:Vmn2r105	UTSW	17	20227761	missense	probably benign	0.12

Posted On

2016-08-02