Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03344:Tmem202'

417368

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tmem202

Ensembl Gene

ENSMUSG00000049526

Gene Name

transmembrane protein 202

Synonyms

4930425N13Rik

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.050) question?

Stock #

IGL03344

Quality Score

Status

Chromosome

Chromosomal Location

59518685-59539847 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 59519068 bp

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 272 (T272A)

Ref Sequence

ENSEMBL: ENSMUSP00000053782 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000055345]

Predicted Effect

possibly damaging
Transcript: ENSMUST00000055345
AA Change: T272A

PolyPhen 2 Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000053782
Gene: ENSMUSG00000049526
AA Change: T272A

Domain	Start	End	E-Value	Type
Pfam:PMP22_Claudin	50	206	2.2e-9	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214580

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700011L22Rik	A	T	8: 79,248,376	I26N	probably damaging	Het
2410089E03Rik	C	A	15: 8,187,458	P720Q	possibly damaging	Het
AI314180	A	C	4: 58,828,538	V965G	probably damaging	Het
Armc4	C	A	18: 7,129,434	G915*	probably null	Het
Atxn7l1	A	G	12: 33,326,066	N47D	probably damaging	Het
BC003331	T	C	1: 150,363,544	E386G	probably damaging	Het
Cer1	A	T	4: 82,884,825	W87R	probably damaging	Het
Chrna2	A	G	14: 66,150,966	K477E	probably damaging	Het
Chtf8	G	A	8: 106,886,272	P12S	probably damaging	Het
Deaf1	A	T	7: 141,297,548	H555Q	probably benign	Het
Dopey1	T	G	9: 86,536,144	I1975M	probably damaging	Het
Fsd2	C	A	7: 81,559,909	V62L	probably benign	Het
Fxyd6	T	G	9: 45,392,250	L81R	probably benign	Het
Htt	T	A	5: 34,879,828	S2086T	probably benign	Het
Htt	T	A	5: 34,907,466	S3008T	probably benign	Het
Mybbp1a	G	T	11: 72,445,202	R447L	probably damaging	Het
Nup210	A	G	6: 91,021,429	V792A	possibly damaging	Het
Olfr342	T	C	2: 36,528,128	S239P	probably damaging	Het
Olfr392	T	A	11: 73,814,177	I302L	probably benign	Het
Prokr1	T	C	6: 87,588,500	D121G	possibly damaging	Het
Puf60	A	G	15: 76,070,380	V548A	possibly damaging	Het
Serpina3c	T	C	12: 104,147,264	I408V	probably benign	Het
Ska2	A	G	11: 87,109,313		probably benign	Het
Slc4a9	T	A	18: 36,535,601	Y745N	probably damaging	Het
Speer4f1	A	G	5: 17,480,334	E209G	possibly damaging	Het
Spg20	T	C	3: 55,121,685	M299T	probably benign	Het
Vegfc	T	A	8: 54,157,151	I114N	possibly damaging	Het
Vmn1r61	T	A	7: 5,610,494	T274S	possibly damaging	Het
Zfpm2	A	G	15: 41,102,774	N753S	probably benign	Het
Zmym6	A	G	4: 127,120,521	T624A	probably damaging	Het

Other mutations in Tmem202

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0011:Tmem202	UTSW	9	59524801	missense	probably benign	0.00
R0011:Tmem202	UTSW	9	59524801	missense	probably benign	0.00
R0711:Tmem202	UTSW	9	59525372	missense	probably damaging	0.99
R1690:Tmem202	UTSW	9	59519108	missense	possibly damaging	0.93
R2127:Tmem202	UTSW	9	59520200	missense	probably benign	0.41
R4747:Tmem202	UTSW	9	59519194	missense	possibly damaging	0.47
R4998:Tmem202	UTSW	9	59524846	missense	probably damaging	0.99
R6916:Tmem202	UTSW	9	59525474	start gained	probably benign
R6929:Tmem202	UTSW	9	59519221	missense	probably benign	0.20
R8326:Tmem202	UTSW	9	59519217	missense	probably benign
R8537:Tmem202	UTSW	9	59519646	missense	probably benign	0.00

Posted On

2016-08-02