Incidental Mutation 'IGL03344:Vmn1r61'
ID417374
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r61
Ensembl Gene ENSMUSG00000094313
Gene Namevomeronasal 1 receptor 61
SynonymsGm7186
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL03344
Quality Score
Status
Chromosome7
Chromosomal Location5610251-5612068 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 5610494 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Serine at position 274 (T274S)
Ref Sequence ENSEMBL: ENSMUSP00000128012 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164880]
Predicted Effect possibly damaging
Transcript: ENSMUST00000164880
AA Change: T274S

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)
SMART Domains Protein: ENSMUSP00000128012
Gene: ENSMUSG00000094313
AA Change: T274S

DomainStartEndE-ValueType
Pfam:TAS2R 1 294 5.3e-12 PFAM
Pfam:7tm_1 20 279 5e-9 PFAM
Pfam:V1R 31 299 9.5e-21 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700011L22Rik A T 8: 79,248,376 I26N probably damaging Het
2410089E03Rik C A 15: 8,187,458 P720Q possibly damaging Het
AI314180 A C 4: 58,828,538 V965G probably damaging Het
Armc4 C A 18: 7,129,434 G915* probably null Het
Atxn7l1 A G 12: 33,326,066 N47D probably damaging Het
BC003331 T C 1: 150,363,544 E386G probably damaging Het
Cer1 A T 4: 82,884,825 W87R probably damaging Het
Chrna2 A G 14: 66,150,966 K477E probably damaging Het
Chtf8 G A 8: 106,886,272 P12S probably damaging Het
Deaf1 A T 7: 141,297,548 H555Q probably benign Het
Dopey1 T G 9: 86,536,144 I1975M probably damaging Het
Fsd2 C A 7: 81,559,909 V62L probably benign Het
Fxyd6 T G 9: 45,392,250 L81R probably benign Het
Htt T A 5: 34,907,466 S3008T probably benign Het
Htt T A 5: 34,879,828 S2086T probably benign Het
Mybbp1a G T 11: 72,445,202 R447L probably damaging Het
Nup210 A G 6: 91,021,429 V792A possibly damaging Het
Olfr342 T C 2: 36,528,128 S239P probably damaging Het
Olfr392 T A 11: 73,814,177 I302L probably benign Het
Prokr1 T C 6: 87,588,500 D121G possibly damaging Het
Puf60 A G 15: 76,070,380 V548A possibly damaging Het
Serpina3c T C 12: 104,147,264 I408V probably benign Het
Ska2 A G 11: 87,109,313 probably benign Het
Slc4a9 T A 18: 36,535,601 Y745N probably damaging Het
Speer4f1 A G 5: 17,480,334 E209G possibly damaging Het
Spg20 T C 3: 55,121,685 M299T probably benign Het
Tmem202 T C 9: 59,519,068 T272A possibly damaging Het
Vegfc T A 8: 54,157,151 I114N possibly damaging Het
Zfpm2 A G 15: 41,102,774 N753S probably benign Het
Zmym6 A G 4: 127,120,521 T624A probably damaging Het
Other mutations in Vmn1r61
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01700:Vmn1r61 APN 7 5611203 missense possibly damaging 0.82
IGL02859:Vmn1r61 APN 7 5611289 missense probably benign 0.37
R0189:Vmn1r61 UTSW 7 5610700 missense probably benign 0.03
R0336:Vmn1r61 UTSW 7 5611067 missense probably benign
R0616:Vmn1r61 UTSW 7 5610999 missense possibly damaging 0.65
R1490:Vmn1r61 UTSW 7 5611243 missense probably benign 0.00
R1737:Vmn1r61 UTSW 7 5611061 missense probably benign 0.01
R1755:Vmn1r61 UTSW 7 5611303 nonsense probably null
R1795:Vmn1r61 UTSW 7 5611325 utr 5 prime probably benign
R3929:Vmn1r61 UTSW 7 5611177 missense probably benign 0.01
R4487:Vmn1r61 UTSW 7 5610925 missense possibly damaging 0.76
R4629:Vmn1r61 UTSW 7 5611250 missense probably benign 0.08
R4785:Vmn1r61 UTSW 7 5611125 nonsense probably null
R4785:Vmn1r61 UTSW 7 5611127 missense probably benign
R5108:Vmn1r61 UTSW 7 5610520 missense probably benign
R5305:Vmn1r61 UTSW 7 5610815 missense probably damaging 1.00
R5914:Vmn1r61 UTSW 7 5610530 missense probably damaging 1.00
R6150:Vmn1r61 UTSW 7 5610679 missense probably benign 0.00
R6232:Vmn1r61 UTSW 7 5610851 missense probably damaging 1.00
R6722:Vmn1r61 UTSW 7 5610688 missense possibly damaging 0.55
R7488:Vmn1r61 UTSW 7 5610768 missense possibly damaging 0.56
R7496:Vmn1r61 UTSW 7 5610431 missense probably benign 0.19
R8353:Vmn1r61 UTSW 7 5610887 missense probably benign 0.11
R8453:Vmn1r61 UTSW 7 5610887 missense probably benign 0.11
Posted On2016-08-02