Incidental Mutation 'IGL03072:Nat8f4'
ID417565
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Nat8f4
Ensembl Gene ENSMUSG00000068299
Gene NameN-acetyltransferase 8 (GCN5-related) family member 4
Synonyms1700019G17Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.065) question?
Stock #IGL03072
Quality Score
Status
Chromosome6
Chromosomal Location85899051-85904884 bp(-) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) A to G at 85900854 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000124071 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000095757] [ENSMUST00000159755]
Predicted Effect probably benign
Transcript: ENSMUST00000095757
SMART Domains Protein: ENSMUSP00000093430
Gene: ENSMUSG00000068299

DomainStartEndE-ValueType
transmembrane domain 33 55 N/A INTRINSIC
Pfam:Acetyltransf_10 75 192 2.5e-11 PFAM
Pfam:Acetyltransf_8 83 200 2.1e-11 PFAM
Pfam:Acetyltransf_7 104 194 3.3e-14 PFAM
Pfam:Acetyltransf_1 111 193 6.3e-17 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000159755
SMART Domains Protein: ENSMUSP00000124071
Gene: ENSMUSG00000068299

DomainStartEndE-ValueType
transmembrane domain 33 55 N/A INTRINSIC
transmembrane domain 60 82 N/A INTRINSIC
low complexity region 117 130 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2210408I21Rik G A 13: 77,259,997 V148I probably benign Het
Ahcyl2 T C 6: 29,906,501 probably benign Het
Ahnak T C 19: 9,006,508 S1719P probably benign Het
C2cd5 A G 6: 143,079,883 I196T possibly damaging Het
Cdhr2 A G 13: 54,726,661 I849V probably benign Het
Cpsf3 A G 12: 21,295,088 K134E possibly damaging Het
Dnaic1 A G 4: 41,602,979 T161A probably benign Het
Gm17093 G T 14: 44,520,672 probably benign Het
Igf2bp2 A G 16: 22,068,141 probably null Het
Lcor T C 19: 41,558,814 V279A possibly damaging Het
Myo9a C A 9: 59,809,442 T475K possibly damaging Het
Neto1 A G 18: 86,498,589 T344A probably benign Het
Olfr1048 A T 2: 86,236,460 M118K probably damaging Het
Olfr371 A G 8: 85,230,510 N5S probably benign Het
Olfr772 A T 10: 129,174,489 D177E probably damaging Het
Pde8a A T 7: 81,308,809 I312F probably damaging Het
Ppp3cb A G 14: 20,531,725 I74T probably damaging Het
Prom1 T C 5: 44,058,662 probably benign Het
Psg29 T C 7: 17,208,794 V240A probably benign Het
Reep4 T C 14: 70,548,235 S238P probably damaging Het
Stxbp2 A T 8: 3,641,971 I538F probably benign Het
Tmprss5 T A 9: 49,109,018 N99K possibly damaging Het
Tph1 G A 7: 46,652,859 T313M probably damaging Het
Tprn T C 2: 25,264,518 S611P probably damaging Het
Upp2 G T 2: 58,755,423 probably null Het
Vezt C A 10: 93,974,033 A549S probably damaging Het
Zfp786 A G 6: 47,821,243 Y254H probably benign Het
Other mutations in Nat8f4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00158:Nat8f4 APN 6 85900987 missense probably benign 0.05
R1341:Nat8f4 UTSW 6 85901424 missense probably damaging 0.96
R1725:Nat8f4 UTSW 6 85901098 nonsense probably null
R1923:Nat8f4 UTSW 6 85901515 missense probably damaging 1.00
R2258:Nat8f4 UTSW 6 85901225 missense possibly damaging 0.84
R3975:Nat8f4 UTSW 6 85901070 missense possibly damaging 0.62
R4697:Nat8f4 UTSW 6 85901386 missense probably benign 0.01
R4784:Nat8f4 UTSW 6 85901499 missense probably benign 0.03
R4924:Nat8f4 UTSW 6 85901419 missense probably benign 0.03
R4991:Nat8f4 UTSW 6 85901140 missense probably benign 0.30
R6074:Nat8f4 UTSW 6 85901187 missense probably damaging 0.98
R7058:Nat8f4 UTSW 6 85901289 missense possibly damaging 0.73
R7790:Nat8f4 UTSW 6 85900891 missense probably benign 0.00
Posted On2016-08-02