Incidental Mutation 'IGL03078:Olfr920'
ID417748
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr920
Ensembl Gene ENSMUSG00000061039
Gene Nameolfactory receptor 920
SynonymsMOR165-6, GA_x6K02T2PVTD-32458442-32459374
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL03078
Quality Score
Status
Chromosome9
Chromosomal Location38752299-38760117 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to T at 38756245 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Stop codon at position 186 (Q186*)
Ref Sequence ENSEMBL: ENSMUSP00000074300 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000074740]
Predicted Effect probably null
Transcript: ENSMUST00000074740
AA Change: Q186*
SMART Domains Protein: ENSMUSP00000074300
Gene: ENSMUSG00000061039
AA Change: Q186*

DomainStartEndE-ValueType
Pfam:7tm_4 31 308 3.2e-47 PFAM
Pfam:7tm_1 41 290 3.6e-22 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 T A 11: 110,276,545 K1482* probably null Het
Adam15 A G 3: 89,345,937 probably benign Het
Adamdec1 C T 14: 68,568,850 R392H possibly damaging Het
Anxa7 T C 14: 20,456,556 K439E probably damaging Het
Arap2 T A 5: 62,733,065 probably benign Het
Asic5 A G 3: 82,014,428 E367G possibly damaging Het
Btbd11 C T 10: 85,632,163 A774V probably damaging Het
Cubn T C 2: 13,287,094 T3307A possibly damaging Het
Dnd1 T C 18: 36,766,144 E8G probably damaging Het
Eif2ak1 T C 5: 143,873,769 I99T probably benign Het
Fras1 C T 5: 96,636,135 R833C probably damaging Het
Hectd1 A G 12: 51,802,236 S362P probably damaging Het
Hs3st4 A G 7: 124,397,446 E445G probably damaging Het
Kcnh1 A G 1: 192,434,800 T21A probably damaging Het
Kif26b G A 1: 178,870,726 R594H probably damaging Het
Lsm14b T C 2: 180,026,728 I74T probably damaging Het
Myh2 T A 11: 67,190,430 S1291T probably benign Het
Myo3b T A 2: 70,286,991 F923I probably damaging Het
Obscn T C 11: 59,078,798 probably null Het
Olfr583 T C 7: 103,051,829 F177S probably damaging Het
Piezo2 A C 18: 63,070,075 M1484R probably damaging Het
Rhoh T A 5: 65,892,888 V167D probably damaging Het
Rspo3 T C 10: 29,504,661 Y119C probably damaging Het
Scpep1 T A 11: 88,935,831 I260F possibly damaging Het
Slc15a3 T A 19: 10,857,245 F497I probably damaging Het
Stom T C 2: 35,315,929 K263E probably damaging Het
Taf4b C A 18: 14,813,554 A478E possibly damaging Het
Ttn C T 2: 76,770,250 probably benign Het
Wdr95 C T 5: 149,611,597 A598V possibly damaging Het
Other mutations in Olfr920
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01686:Olfr920 APN 9 38756254 missense probably damaging 1.00
IGL01728:Olfr920 APN 9 38756095 missense possibly damaging 0.63
IGL01867:Olfr920 APN 9 38755898 missense probably damaging 1.00
IGL02271:Olfr920 APN 9 38756488 missense probably benign
R0166:Olfr920 UTSW 9 38756188 missense probably benign
R0446:Olfr920 UTSW 9 38755818 missense probably damaging 1.00
R0453:Olfr920 UTSW 9 38756129 missense probably damaging 0.99
R0556:Olfr920 UTSW 9 38755745 missense possibly damaging 0.88
R1585:Olfr920 UTSW 9 38756420 missense probably damaging 1.00
R2847:Olfr920 UTSW 9 38756036 missense possibly damaging 0.89
R4676:Olfr920 UTSW 9 38755659 start gained probably benign
R4825:Olfr920 UTSW 9 38756407 missense probably damaging 1.00
R5026:Olfr920 UTSW 9 38755745 missense probably benign 0.01
R5144:Olfr920 UTSW 9 38756393 missense possibly damaging 0.90
R5573:Olfr920 UTSW 9 38755704 missense probably damaging 1.00
R5872:Olfr920 UTSW 9 38756116 missense probably benign 0.06
R6131:Olfr920 UTSW 9 38756066 missense probably damaging 1.00
R6729:Olfr920 UTSW 9 38755828 missense probably benign 0.00
R7731:Olfr920 UTSW 9 38756246 missense possibly damaging 0.90
R7800:Olfr920 UTSW 9 38756618 missense probably damaging 0.97
Posted On2016-08-02