Incidental Mutation 'IGL03079:Ceacam11'
ID417790
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ceacam11
Ensembl Gene ENSMUSG00000030368
Gene Namecarcinoembryonic antigen-related cell adhesion molecule 11
SynonymsCeacam11-C1, Ceacam11-C3, Ceacam11-C4, 1600015D01Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.034) question?
Stock #IGL03079
Quality Score
Status
Chromosome7
Chromosomal Location17972124-17978556 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 17978436 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 270 (N270S)
Ref Sequence ENSEMBL: ENSMUSP00000092393 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094799]
Predicted Effect probably benign
Transcript: ENSMUST00000094799
AA Change: N270S

PolyPhen 2 Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
SMART Domains Protein: ENSMUSP00000092393
Gene: ENSMUSG00000030368
AA Change: N270S

DomainStartEndE-ValueType
IG_like 40 141 8.06e0 SMART
IG_like 160 261 8.5e0 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alx1 T A 10: 103,009,348 H274L probably damaging Het
Arl6ip4 A T 5: 124,116,927 H59L possibly damaging Het
C1ra A G 6: 124,519,835 Y410C probably damaging Het
Cmtr1 T A 17: 29,663,293 N39K possibly damaging Het
Cmya5 T C 13: 93,097,701 D293G possibly damaging Het
Cyp2d11 T C 15: 82,390,966 E260G probably damaging Het
Dnajc13 C T 9: 104,212,869 W700* probably null Het
Efemp2 G T 19: 5,475,127 L20F probably damaging Het
Grasp T C 15: 101,230,567 V162A probably damaging Het
Hars G A 18: 36,770,503 L289F probably damaging Het
Hdlbp A G 1: 93,413,940 probably benign Het
Iqgap3 A T 3: 88,113,170 M374L probably benign Het
Lrig2 A T 3: 104,490,971 W281R probably damaging Het
Lyg2 C T 1: 37,907,646 E185K possibly damaging Het
Maml2 A G 9: 13,621,616 probably benign Het
March11 T C 15: 26,311,058 S207P probably damaging Het
Nipa2 A T 7: 55,933,457 V180E probably damaging Het
Olfr731 A T 14: 50,238,124 C254S possibly damaging Het
P2rx5 A G 11: 73,164,888 D57G possibly damaging Het
Pxdn T C 12: 30,002,998 I1058T probably damaging Het
Rxfp3 C A 15: 11,036,823 M154I possibly damaging Het
Slc3a1 T A 17: 85,059,823 Y479* probably null Het
Tecrl G A 5: 83,294,600 H209Y probably damaging Het
Ttll5 T C 12: 85,876,558 Y270H probably damaging Het
Usp34 A G 11: 23,432,247 E1986G possibly damaging Het
Zfp719 A G 7: 43,591,166 Y726C probably damaging Het
Zfp810 T C 9: 22,284,127 E7G probably damaging Het
Other mutations in Ceacam11
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00844:Ceacam11 APN 7 17973670 missense possibly damaging 0.82
IGL01161:Ceacam11 APN 7 17978510 missense possibly damaging 0.95
IGL01744:Ceacam11 APN 7 17973398 missense possibly damaging 0.95
IGL02052:Ceacam11 APN 7 17973623 missense probably benign 0.09
IGL02337:Ceacam11 APN 7 17973625 missense probably benign 0.09
R1902:Ceacam11 UTSW 7 17975327 missense probably benign 0.05
R2204:Ceacam11 UTSW 7 17975348 missense possibly damaging 0.92
R2851:Ceacam11 UTSW 7 17978526 missense probably benign 0.01
R3237:Ceacam11 UTSW 7 17973454 missense probably benign 0.02
R4786:Ceacam11 UTSW 7 17972314 critical splice donor site probably null
Posted On2016-08-02