Incidental Mutation 'IGL03082:Slc35f1'
ID417898
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc35f1
Ensembl Gene ENSMUSG00000038602
Gene Namesolute carrier family 35, member F1
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL03082
Quality Score
Status
Chromosome10
Chromosomal Location52690533-53111622 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 52933138 bp
ZygosityHeterozygous
Amino Acid Change Valine to Isoleucine at position 74 (V74I)
Ref Sequence ENSEMBL: ENSMUSP00000101113 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105473]
Predicted Effect probably benign
Transcript: ENSMUST00000105473
AA Change: V74I

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000101113
Gene: ENSMUSG00000038602
AA Change: V74I

DomainStartEndE-ValueType
low complexity region 3 20 N/A INTRINSIC
Pfam:SLC35F 56 355 1.4e-151 PFAM
Pfam:CRT-like 66 315 2.3e-13 PFAM
Pfam:EamA 217 355 1.7e-9 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a knock-out allele exhibit no detectable phenotypic abnormalities. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Asic1 T A 15: 99,696,547 N324K probably benign Het
Atpaf2 T C 11: 60,403,844 E251G probably damaging Het
Cacna1d T C 14: 30,099,233 K1109E probably damaging Het
Ces1d C A 8: 93,169,718 probably null Het
Chst1 C T 2: 92,613,933 T250I possibly damaging Het
Cpne6 T C 14: 55,516,303 L406P probably damaging Het
Cryz A G 3: 154,604,926 M8V probably damaging Het
Dpysl2 T C 14: 66,808,010 E438G probably damaging Het
Elovl1 T C 4: 118,430,880 I71T probably benign Het
Eml2 T A 7: 19,201,877 Y679N probably damaging Het
Fam185a G A 5: 21,455,838 V284I possibly damaging Het
Fpgs C T 2: 32,685,757 W391* probably null Het
Hdac11 C T 6: 91,173,103 P295S probably damaging Het
Herc2 A T 7: 56,185,923 I3260F probably benign Het
Hltf G A 3: 20,064,559 probably benign Het
Immp2l T G 12: 41,110,901 V66G possibly damaging Het
Lrrc4c T C 2: 97,630,586 I519T probably benign Het
Megf8 A G 7: 25,330,236 T402A probably benign Het
Mttp T G 3: 138,123,795 I111L probably benign Het
Mycbp2 T A 14: 103,204,369 I1987F probably benign Het
Ncr1 T A 7: 4,341,242 probably benign Het
Nedd4 G A 9: 72,677,394 probably null Het
Nnt A G 13: 119,396,868 F87S probably damaging Het
Nol6 A G 4: 41,115,878 probably benign Het
Pdzd3 A T 9: 44,250,786 S39T possibly damaging Het
Pkhd1 A T 1: 20,565,633 I491N probably damaging Het
Plcxd2 T C 16: 45,965,110 I311V probably damaging Het
Pou2f3 C A 9: 43,146,915 probably null Het
Rgsl1 G A 1: 153,799,947 T836I possibly damaging Het
Rttn G A 18: 88,983,948 G328D probably damaging Het
Serpina11 T C 12: 103,986,301 E77G probably benign Het
Slc7a6 A G 8: 106,193,222 probably null Het
Smco2 A G 6: 146,860,044 T154A possibly damaging Het
Tcerg1 A G 18: 42,573,357 Y1033C probably damaging Het
Tmem87a A G 2: 120,397,366 F100S possibly damaging Het
Tssk4 T C 14: 55,651,061 F129S probably damaging Het
Wdr43 C T 17: 71,638,341 T315I probably damaging Het
Other mutations in Slc35f1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00434:Slc35f1 APN 10 53062452 missense probably damaging 1.00
IGL01073:Slc35f1 APN 10 53021960 missense probably benign 0.16
IGL01433:Slc35f1 APN 10 53073446 splice site probably benign
IGL01566:Slc35f1 APN 10 53089455 missense probably damaging 1.00
IGL02693:Slc35f1 APN 10 52933128 missense probably damaging 1.00
IGL02870:Slc35f1 APN 10 52933207 missense possibly damaging 0.82
R0884:Slc35f1 UTSW 10 53089347 missense probably damaging 1.00
R1340:Slc35f1 UTSW 10 53089454 missense probably damaging 1.00
R1781:Slc35f1 UTSW 10 53062436 splice site probably null
R1813:Slc35f1 UTSW 10 52933195 missense probably damaging 1.00
R1908:Slc35f1 UTSW 10 53021904 missense possibly damaging 0.84
R2044:Slc35f1 UTSW 10 53089347 missense probably damaging 1.00
R2518:Slc35f1 UTSW 10 53073534 missense probably benign 0.07
R3872:Slc35f1 UTSW 10 53021910 missense possibly damaging 0.87
R3934:Slc35f1 UTSW 10 53108218 missense probably damaging 1.00
R3935:Slc35f1 UTSW 10 53108218 missense probably damaging 1.00
R3936:Slc35f1 UTSW 10 53108218 missense probably damaging 1.00
R4118:Slc35f1 UTSW 10 53089368 missense probably damaging 0.98
R4921:Slc35f1 UTSW 10 53062602 missense probably damaging 0.99
R5116:Slc35f1 UTSW 10 53021895 missense probably benign 0.39
R5378:Slc35f1 UTSW 10 52691061 missense possibly damaging 0.86
R5387:Slc35f1 UTSW 10 53108164 missense probably damaging 1.00
R5500:Slc35f1 UTSW 10 52933222 missense probably damaging 0.99
R5590:Slc35f1 UTSW 10 53108178 missense possibly damaging 0.63
R5743:Slc35f1 UTSW 10 53089450 missense probably benign 0.06
R5916:Slc35f1 UTSW 10 52933221 nonsense probably null
R6985:Slc35f1 UTSW 10 53021911 missense probably benign 0.02
R7068:Slc35f1 UTSW 10 53062500 missense probably damaging 1.00
R7295:Slc35f1 UTSW 10 53062541 missense probably benign 0.00
R7427:Slc35f1 UTSW 10 53089414 missense probably damaging 1.00
R7428:Slc35f1 UTSW 10 53089414 missense probably damaging 1.00
R8334:Slc35f1 UTSW 10 53108148 missense possibly damaging 0.84
Posted On2016-08-02