Incidental Mutation 'IGL03092:Clec3b'
ID418435
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec3b
Ensembl Gene ENSMUSG00000025784
Gene NameC-type lectin domain family 3, member b
SynonymsTna
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL03092
Quality Score
Status
Chromosome9
Chromosomal Location123150946-123157432 bp(+) (GRCm38)
Type of Mutationstart gained
DNA Base Change (assembly) A to T at 123151035 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000026890 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000026890]
Predicted Effect probably benign
Transcript: ENSMUST00000026890
SMART Domains Protein: ENSMUSP00000026890
Gene: ENSMUSG00000025784

DomainStartEndE-ValueType
low complexity region 27 36 N/A INTRINSIC
CLECT 71 198 1.02e-25 SMART
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a null allele develop pronounced cervical lordosis and thoracic kyphosis associated with wedge-shaped deformities of the vertebrae, growth plate irregularities, and an asymmetric development of the intervertebral disks. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700006A11Rik A G 3: 124,406,470 L491P probably damaging Het
5430419D17Rik G T 7: 131,201,798 probably null Het
Abcc6 T A 7: 45,986,470 D1051V probably damaging Het
Aqr T A 2: 114,158,943 E133V probably benign Het
Bag6 A G 17: 35,145,627 N911D probably damaging Het
BC024978 T C 7: 27,201,136 M180T probably damaging Het
Ces4a C T 8: 105,148,204 probably benign Het
Cnot1 T C 8: 95,769,615 probably benign Het
Ctsg T A 14: 56,099,960 *262L probably null Het
Cyp17a1 T A 19: 46,672,611 H78L possibly damaging Het
Dcaf13 C A 15: 39,127,976 probably benign Het
Dcun1d1 G T 3: 35,920,992 Q52K possibly damaging Het
Ddb1 C T 19: 10,612,945 R279W probably damaging Het
Dock1 A G 7: 134,765,216 probably benign Het
Dsel A G 1: 111,860,063 L914P probably damaging Het
Fbxo31 A G 8: 121,560,018 F174L probably benign Het
Gm9116 A G 3: 93,910,206 noncoding transcript Het
Gspt1 C T 16: 11,238,899 V211I probably benign Het
Hmgb1 A T 5: 149,050,698 S14T probably benign Het
Igsf8 A G 1: 172,312,529 probably benign Het
Klf13 A G 7: 63,891,669 F237L probably damaging Het
Mon2 A T 10: 123,018,100 I962N probably damaging Het
Nfx1 A G 4: 41,024,851 D1108G probably damaging Het
Nr2e1 T C 10: 42,571,482 Y178C probably damaging Het
Olfr1426 C A 19: 12,087,866 E309* probably null Het
Olfr646 A T 7: 104,106,647 I123F probably damaging Het
Pde3b A T 7: 114,523,348 H717L probably damaging Het
Polr1b T C 2: 129,123,129 Y712H probably damaging Het
Pramef25 C A 4: 143,950,197 K112N probably damaging Het
Rnf157 T A 11: 116,347,969 probably null Het
Ros1 T C 10: 52,098,806 E1561G probably damaging Het
Serpina6 A G 12: 103,653,895 probably null Het
St18 A G 1: 6,768,894 probably benign Het
Ugp2 A G 11: 21,329,722 probably benign Het
Vmn1r70 T C 7: 10,634,259 S225P probably benign Het
Zfp641 T C 15: 98,290,516 D161G probably damaging Het
Other mutations in Clec3b
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02441:Clec3b APN 9 123151113 missense possibly damaging 0.61
IGL02884:Clec3b APN 9 123156762 missense probably benign 0.00
R0025:Clec3b UTSW 9 123157025 missense probably benign
R6761:Clec3b UTSW 9 123156939 missense probably damaging 1.00
Posted On2016-08-02