Incidental Mutation 'IGL03095:Lyg1'
ID418554
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lyg1
Ensembl Gene ENSMUSG00000026085
Gene Namelysozyme G-like 1
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL03095
Quality Score
Status
Chromosome1
Chromosomal Location37946736-37957759 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 37950768 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000110544 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000027254] [ENSMUST00000114894]
Predicted Effect probably benign
Transcript: ENSMUST00000027254
SMART Domains Protein: ENSMUSP00000027254
Gene: ENSMUSG00000026085

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
SCOP:d153l__ 23 197 1e-47 SMART
PDB:154L|A 24 197 2e-48 PDB
Predicted Effect probably benign
Transcript: ENSMUST00000114894
SMART Domains Protein: ENSMUSP00000110544
Gene: ENSMUSG00000026085

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
SCOP:d153l__ 23 197 8e-48 SMART
PDB:154L|A 24 197 1e-48 PDB
Predicted Effect noncoding transcript
Transcript: ENSMUST00000129513
Predicted Effect noncoding transcript
Transcript: ENSMUST00000144184
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Bche A G 3: 73,701,883 L70P probably damaging Het
Cacna1h C A 17: 25,383,778 probably benign Het
Ccdc60 A T 5: 116,146,215 probably benign Het
Cep152 T C 2: 125,618,451 N194D probably benign Het
Chodl T A 16: 78,941,433 D96E probably damaging Het
Clca3b C A 3: 144,846,910 G122* probably null Het
Crybg1 T C 10: 43,989,249 I1411V probably damaging Het
Dock9 A C 14: 121,639,528 V477G probably damaging Het
Fam149a T A 8: 45,341,228 E632D probably damaging Het
Gabra4 A G 5: 71,624,015 V351A probably damaging Het
Gen1 T A 12: 11,248,264 I319L probably benign Het
Gne C A 4: 44,055,211 D255Y probably damaging Het
Gpr146 A G 5: 139,392,950 H169R probably benign Het
Htatip2 A G 7: 49,759,774 E92G probably benign Het
Ipcef1 A G 10: 6,919,732 S223P probably damaging Het
Kcnmb2 T A 3: 32,198,127 *37R probably null Het
Lin54 A T 5: 100,454,478 V400E probably damaging Het
Ltbp1 C A 17: 75,282,418 Q511K possibly damaging Het
Nampt T A 12: 32,842,686 V324D possibly damaging Het
Nat8b-ps T G 6: 85,932,968 probably benign Het
Neb G A 2: 52,169,088 H213Y probably damaging Het
Nfkb1 T C 3: 135,618,830 E179G possibly damaging Het
Nlrc5 T A 8: 94,521,908 probably benign Het
Olfr102 T A 17: 37,313,773 I204F probably benign Het
Olfr1085 A T 2: 86,658,431 L9Q possibly damaging Het
Pcdh15 G A 10: 74,355,874 V601M probably damaging Het
Pigc G A 1: 161,970,776 R109Q possibly damaging Het
Plxna2 A G 1: 194,801,127 N1582S probably damaging Het
Pros1 C T 16: 62,907,769 Q279* probably null Het
Psmb5 A G 14: 54,616,557 S155P probably damaging Het
Rock2 T A 12: 16,953,340 D393E probably benign Het
Slc25a21 T C 12: 56,738,625 T156A probably benign Het
Slc44a1 T A 4: 53,536,374 Y183* probably null Het
Sytl2 C T 7: 90,392,434 P580L probably damaging Het
Tktl2 G T 8: 66,512,284 V165F probably damaging Het
Trim55 A G 3: 19,674,465 E480G probably benign Het
Vmn2r92 T A 17: 18,166,710 S104T possibly damaging Het
Vps51 C T 19: 6,070,048 R490H probably damaging Het
Wdr43 G A 17: 71,641,287 V391I probably benign Het
Zranb1 T G 7: 132,949,906 Y121* probably null Het
Other mutations in Lyg1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01389:Lyg1 APN 1 37949930 missense probably damaging 1.00
R0411:Lyg1 UTSW 1 37949896 missense possibly damaging 0.92
R1171:Lyg1 UTSW 1 37947224 missense probably damaging 1.00
R2126:Lyg1 UTSW 1 37950674 missense probably damaging 0.96
R3715:Lyg1 UTSW 1 37950678 missense probably damaging 0.96
R3744:Lyg1 UTSW 1 37949842 missense probably benign 0.37
R4660:Lyg1 UTSW 1 37946861 utr 3 prime probably benign
R5040:Lyg1 UTSW 1 37950811 intron probably benign
R5769:Lyg1 UTSW 1 37950750 missense unknown
R5792:Lyg1 UTSW 1 37947267 missense probably benign 0.00
R5800:Lyg1 UTSW 1 37946953 missense probably damaging 1.00
R7318:Lyg1 UTSW 1 37949855 missense probably benign 0.44
Z1176:Lyg1 UTSW 1 37947177 missense probably null 1.00
Posted On2016-08-02