Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03105:Tcerg1l'

418941

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tcerg1l

Ensembl Gene

ENSMUSG00000091002

Gene Name

transcription elongation regulator 1-like

Synonyms

5730476P14Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL03105

Quality Score

Status

Chromosome

Chromosomal Location

137810703-137999459 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to T at 137850173 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000124476 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160436]

AlphaFold

Q3B807

Predicted Effect

probably benign
Transcript: ENSMUST00000160436

SMART Domains

Protein: ENSMUSP00000124476
Gene: ENSMUSG00000091002

Domain	Start	End	E-Value	Type
low complexity region	6	44	N/A	INTRINSIC
low complexity region	52	97	N/A	INTRINSIC
WW	146	178	2.11e1	SMART
low complexity region	235	249	N/A	INTRINSIC
WW	344	376	3.29e-4	SMART
low complexity region	402	415	N/A	INTRINSIC
FF	454	507	4.57e-12	SMART
FF	520	574	1.53e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161213

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 48 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adss1	A	G	12: 112,599,155 (GRCm39)	I129V	probably benign	Het
Ankrd35	A	G	3: 96,591,373 (GRCm39)	H553R	probably benign	Het
Brca2	A	G	5: 150,483,950 (GRCm39)	K2923R	probably benign	Het
Cadm3	A	T	1: 173,172,583 (GRCm39)	L174M	probably damaging	Het
Car10	T	C	11: 92,991,101 (GRCm39)	V17A	probably benign	Het
Cep290	A	G	10: 100,387,686 (GRCm39)	K1956E	possibly damaging	Het
Cfhr1	T	A	1: 139,475,565 (GRCm39)		probably benign	Het
Crim1	A	T	17: 78,623,179 (GRCm39)		probably benign	Het
Dedd	G	A	1: 171,168,486 (GRCm39)	R224H	probably damaging	Het
F7	A	T	8: 13,084,001 (GRCm39)	I229L	probably null	Het
Igkv17-121	A	T	6: 68,014,284 (GRCm39)	Q112L	probably damaging	Het
Kcnk13	G	A	12: 100,027,369 (GRCm39)	R148Q	probably damaging	Het
Klk13	T	C	7: 43,370,904 (GRCm39)	L51P	probably benign	Het
Ldb2	A	G	5: 44,956,715 (GRCm39)	S41P	possibly damaging	Het
Magi2	A	G	5: 20,748,616 (GRCm39)	D767G	probably damaging	Het
Mical3	T	C	6: 121,019,199 (GRCm39)	T8A	probably benign	Het
Mkln1	G	T	6: 31,435,994 (GRCm39)	E318*	probably null	Het
Mx1	C	T	16: 97,257,554 (GRCm39)	V68I	possibly damaging	Het
Mylk2	T	C	2: 152,759,279 (GRCm39)	V350A	possibly damaging	Het
Nav2	T	A	7: 49,114,627 (GRCm39)	S870R	probably damaging	Het
Onecut2	A	T	18: 64,474,579 (GRCm39)	K358*	probably null	Het
Or51b4	A	G	7: 103,531,339 (GRCm39)	I37T	possibly damaging	Het
Or52n2c	A	T	7: 104,574,971 (GRCm39)		probably benign	Het
Or7a40	T	C	16: 16,491,390 (GRCm39)	T152A	probably benign	Het
Or7g16	T	C	9: 18,726,685 (GRCm39)	R302G	probably benign	Het
Orai3	A	G	7: 127,372,725 (GRCm39)		probably benign	Het
Rad54b	A	G	4: 11,615,569 (GRCm39)	N859S	probably benign	Het
Saxo4	A	G	19: 10,454,384 (GRCm39)		probably benign	Het
Sec23b	C	T	2: 144,423,940 (GRCm39)	R530W	probably damaging	Het
Slc25a35	T	C	11: 68,859,496 (GRCm39)	F3S	probably damaging	Het
Slc7a11	A	T	3: 50,326,788 (GRCm39)	I491K	possibly damaging	Het
Srrt	A	T	5: 137,298,106 (GRCm39)	N317K	possibly damaging	Het
Sspo	T	C	6: 48,450,592 (GRCm39)		probably benign	Het
Taf2	A	C	15: 54,909,195 (GRCm39)	D683E	probably benign	Het
Tasor	T	A	14: 27,164,509 (GRCm39)	C272S	probably damaging	Het
Tg	G	T	15: 66,586,955 (GRCm39)	V1578F	probably benign	Het
Tmem43	G	A	6: 91,457,682 (GRCm39)	G188D	probably damaging	Het
Tnfrsf8	T	C	4: 145,025,354 (GRCm39)	Y73C	probably damaging	Het
Ttc21a	A	G	9: 119,771,642 (GRCm39)	Y147C	probably benign	Het
Ttn	T	C	2: 76,608,394 (GRCm39)	D17843G	probably damaging	Het
Ttn	T	A	2: 76,642,521 (GRCm39)	D11592V	probably damaging	Het
Tubgcp5	T	A	7: 55,475,329 (GRCm39)	I842N	probably damaging	Het
Unc80	A	T	1: 66,511,258 (GRCm39)	T89S	probably damaging	Het
Usp28	T	C	9: 48,950,355 (GRCm39)	M928T	probably damaging	Het
Usp43	A	G	11: 67,770,802 (GRCm39)	S611P	possibly damaging	Het
Utp20	A	G	10: 88,626,958 (GRCm39)	V1000A	probably benign	Het
Zfp263	T	C	16: 3,566,824 (GRCm39)	C380R	probably damaging	Het
Zfyve1	A	C	12: 83,605,413 (GRCm39)	C14G	probably damaging	Het

Other mutations in Tcerg1l

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00504:Tcerg1l	APN	7	137,811,533 (GRCm39)	missense	probably damaging	0.99
IGL01402:Tcerg1l	APN	7	137,861,568 (GRCm39)	missense	probably damaging	0.98
IGL01510:Tcerg1l	APN	7	137,996,034 (GRCm39)	splice site	probably benign
IGL01638:Tcerg1l	APN	7	137,881,805 (GRCm39)	missense	probably damaging	1.00
IGL01710:Tcerg1l	APN	7	137,996,789 (GRCm39)	missense	possibly damaging	0.81
IGL02547:Tcerg1l	APN	7	137,850,100 (GRCm39)	critical splice donor site	probably null
IGL02887:Tcerg1l	APN	7	137,831,619 (GRCm39)	missense	probably damaging	1.00
IGL03348:Tcerg1l	APN	7	137,815,100 (GRCm39)	missense	probably damaging	0.97
R0378:Tcerg1l	UTSW	7	137,878,384 (GRCm39)	missense	probably benign	0.01
R1474:Tcerg1l	UTSW	7	137,881,804 (GRCm39)	missense	probably damaging	0.99
R1589:Tcerg1l	UTSW	7	137,963,496 (GRCm39)	missense	probably damaging	0.99
R1658:Tcerg1l	UTSW	7	137,995,909 (GRCm39)	missense	probably damaging	0.98
R1792:Tcerg1l	UTSW	7	137,963,595 (GRCm39)	missense	probably benign	0.07
R1807:Tcerg1l	UTSW	7	137,996,826 (GRCm39)	missense	probably benign	0.34
R2920:Tcerg1l	UTSW	7	137,850,108 (GRCm39)	missense	probably damaging	0.99
R3148:Tcerg1l	UTSW	7	137,861,596 (GRCm39)	missense	probably benign
R4106:Tcerg1l	UTSW	7	137,861,673 (GRCm39)	missense	probably damaging	0.99
R4180:Tcerg1l	UTSW	7	137,878,405 (GRCm39)	critical splice acceptor site	probably null
R4241:Tcerg1l	UTSW	7	137,999,361 (GRCm39)	missense	unknown
R4898:Tcerg1l	UTSW	7	137,819,786 (GRCm39)	missense	probably damaging	0.99
R5652:Tcerg1l	UTSW	7	137,881,775 (GRCm39)	missense	probably damaging	0.97
R6646:Tcerg1l	UTSW	7	137,996,912 (GRCm39)	splice site	probably null
R6824:Tcerg1l	UTSW	7	137,995,844 (GRCm39)	critical splice donor site	probably null
R7414:Tcerg1l	UTSW	7	137,819,786 (GRCm39)	missense	probably damaging	0.97
R7490:Tcerg1l	UTSW	7	137,861,557 (GRCm39)	missense	probably damaging	1.00
R8810:Tcerg1l	UTSW	7	137,811,526 (GRCm39)	missense	possibly damaging	0.79
R8889:Tcerg1l	UTSW	7	137,999,260 (GRCm39)	nonsense	probably null
R8892:Tcerg1l	UTSW	7	137,999,260 (GRCm39)	nonsense	probably null
R9146:Tcerg1l	UTSW	7	137,831,588 (GRCm39)	missense	probably damaging	1.00
R9374:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9392:Tcerg1l	UTSW	7	137,815,164 (GRCm39)	missense	probably damaging	0.98
R9402:Tcerg1l	UTSW	7	137,811,551 (GRCm39)	missense	probably damaging	0.99
R9428:Tcerg1l	UTSW	7	137,811,490 (GRCm39)	missense	probably damaging	0.99
R9551:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9552:Tcerg1l	UTSW	7	137,995,998 (GRCm39)	missense	possibly damaging	0.95
R9572:Tcerg1l	UTSW	7	137,881,787 (GRCm39)	missense	probably benign	0.07
R9624:Tcerg1l	UTSW	7	137,995,923 (GRCm39)	missense	possibly damaging	0.71

Posted On

2016-08-02