Incidental Mutation 'R0480:Ascc3'
| ID |
41950 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ascc3
|
| Ensembl Gene |
ENSMUSG00000038774 |
| Gene Name |
activating signal cointegrator 1 complex subunit 3 |
| Synonyms |
Helic1, B630009I04Rik, ASC1p200 |
| MMRRC Submission |
038680-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.961)
|
| Stock # |
R0480 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
50468756-50727300 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 50611348 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1563
(V1563A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036726
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035606]
|
| AlphaFold |
E9PZJ8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000035606
AA Change: V1563A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036726
Gene: ENSMUSG00000038774
AA Change: V1563A
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
55 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
124 |
135 |
N/A |
INTRINSIC |
|
coiled coil region
|
329 |
356 |
N/A |
INTRINSIC |
|
DEXDc
|
474 |
686 |
1.71e-29 |
SMART |
|
AAA
|
492 |
674 |
8.15e-2 |
SMART |
|
Blast:DEXDc
|
718 |
763 |
4e-18 |
BLAST |
|
HELICc
|
770 |
858 |
6.01e-16 |
SMART |
|
Sec63
|
979 |
1288 |
3.53e-111 |
SMART |
|
DEXDc
|
1324 |
1528 |
8.88e-28 |
SMART |
|
AAA
|
1342 |
1492 |
4.27e-1 |
SMART |
|
HELICc
|
1605 |
1695 |
2.28e-16 |
SMART |
|
Sec63
|
1813 |
2178 |
6.37e-118 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219085
|
| Meta Mutation Damage Score |
0.8047 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.3%
- 20x: 92.6%
|
| Validation Efficiency |
99% (117/118) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
|
| Allele List at MGI |
All alleles(16) : Targeted(2) Gene trapped(14)
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
C |
T |
11: 58,771,012 (GRCm39) |
L165F |
probably damaging |
Het |
| Adamts18 |
A |
G |
8: 114,465,450 (GRCm39) |
V714A |
possibly damaging |
Het |
| Adamtsl1 |
G |
T |
4: 86,171,055 (GRCm39) |
A518S |
probably benign |
Het |
| Adcy2 |
C |
T |
13: 68,880,231 (GRCm39) |
V363M |
probably damaging |
Het |
| Ago4 |
G |
T |
4: 126,419,870 (GRCm39) |
Q36K |
probably benign |
Het |
| Akr1a1 |
A |
G |
4: 116,497,044 (GRCm39) |
V172A |
possibly damaging |
Het |
| Alkbh2 |
T |
A |
5: 114,263,596 (GRCm39) |
N137I |
probably damaging |
Het |
| Ank3 |
T |
A |
10: 69,715,756 (GRCm39) |
S470T |
probably damaging |
Het |
| Ankrd12 |
T |
C |
17: 66,356,823 (GRCm39) |
T65A |
possibly damaging |
Het |
| Aox1 |
A |
T |
1: 58,082,810 (GRCm39) |
|
probably benign |
Het |
| Arhgap11a |
A |
T |
2: 113,670,163 (GRCm39) |
I320N |
probably benign |
Het |
| Arhgap17 |
G |
A |
7: 122,893,867 (GRCm39) |
H518Y |
probably damaging |
Het |
| Atf2 |
G |
A |
2: 73,649,500 (GRCm39) |
|
probably benign |
Het |
| Bmpr2 |
C |
T |
1: 59,884,818 (GRCm39) |
T268I |
probably damaging |
Het |
| Bpifb9a |
A |
G |
2: 154,106,608 (GRCm39) |
I380V |
probably benign |
Het |
| C2cd2 |
G |
A |
16: 97,678,348 (GRCm39) |
T363I |
probably benign |
Het |
| Catsperg2 |
T |
G |
7: 29,420,723 (GRCm39) |
N190H |
probably damaging |
Het |
| Ccdc138 |
T |
C |
10: 58,397,789 (GRCm39) |
L543S |
probably damaging |
Het |
| Ccdc170 |
A |
T |
10: 4,468,939 (GRCm39) |
K162N |
probably benign |
Het |
| Cdca5 |
G |
T |
19: 6,140,328 (GRCm39) |
R163L |
probably damaging |
Het |
| Cdh24 |
A |
G |
14: 54,870,054 (GRCm39) |
F239S |
probably benign |
Het |
| Cdkl3 |
T |
C |
11: 51,895,882 (GRCm39) |
V43A |
probably damaging |
Het |
| Cep152 |
G |
T |
2: 125,423,639 (GRCm39) |
Q921K |
possibly damaging |
Het |
| Cftr |
G |
A |
6: 18,274,517 (GRCm39) |
|
probably benign |
Het |
| Chmp5 |
T |
C |
4: 40,948,690 (GRCm39) |
|
probably benign |
Het |
| Cit |
T |
A |
5: 116,071,452 (GRCm39) |
|
probably benign |
Het |
| Cngb3 |
T |
A |
4: 19,309,517 (GRCm39) |
|
probably benign |
Het |
| Cnr2 |
A |
G |
4: 135,644,912 (GRCm39) |
E330G |
probably benign |
Het |
| Cyp21a1 |
A |
T |
17: 35,020,800 (GRCm39) |
L473Q |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,420,696 (GRCm39) |
T575A |
probably benign |
Het |
| Dedd2 |
A |
G |
7: 24,903,050 (GRCm39) |
V303A |
probably damaging |
Het |
| Dmd |
G |
T |
X: 83,469,344 (GRCm39) |
A2370S |
probably benign |
Het |
| Dnah10 |
T |
A |
5: 124,885,915 (GRCm39) |
N3009K |
probably damaging |
Het |
| Dnajc13 |
G |
T |
9: 104,077,708 (GRCm39) |
N934K |
probably damaging |
Het |
| Dock1 |
C |
T |
7: 134,339,447 (GRCm39) |
L106F |
probably damaging |
Het |
| Fat3 |
A |
G |
9: 15,909,025 (GRCm39) |
Y2326H |
probably benign |
Het |
| Fhl5 |
A |
T |
4: 25,207,101 (GRCm39) |
C222* |
probably null |
Het |
| Gnmt |
T |
C |
17: 47,036,854 (GRCm39) |
T252A |
probably benign |
Het |
| Gpi-ps |
A |
G |
8: 5,689,888 (GRCm39) |
|
noncoding transcript |
Het |
| Gsta5 |
C |
T |
9: 78,210,099 (GRCm39) |
A135V |
probably benign |
Het |
| Gtf2f1 |
A |
G |
17: 57,311,307 (GRCm39) |
|
probably null |
Het |
| Gtf3a |
T |
C |
5: 146,890,039 (GRCm39) |
Y187H |
probably damaging |
Het |
| Hdac2 |
A |
G |
10: 36,850,788 (GRCm39) |
Y14C |
probably damaging |
Het |
| Hnrnph1 |
T |
G |
11: 50,276,589 (GRCm39) |
|
probably benign |
Het |
| Homer2 |
T |
C |
7: 81,268,351 (GRCm39) |
D92G |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,277,335 (GRCm39) |
S2885P |
probably damaging |
Het |
| Insr |
A |
G |
8: 3,211,770 (GRCm39) |
S1084P |
probably damaging |
Het |
| Ints11 |
T |
A |
4: 155,972,081 (GRCm39) |
V362E |
probably damaging |
Het |
| Kank2 |
T |
C |
9: 21,691,195 (GRCm39) |
N513S |
probably damaging |
Het |
| Kl |
T |
G |
5: 150,876,753 (GRCm39) |
V191G |
probably damaging |
Het |
| Krt23 |
A |
G |
11: 99,377,524 (GRCm39) |
|
probably null |
Het |
| Lama3 |
A |
C |
18: 12,583,481 (GRCm39) |
T690P |
possibly damaging |
Het |
| Lamb1 |
G |
A |
12: 31,332,720 (GRCm39) |
A281T |
possibly damaging |
Het |
| Lck |
T |
C |
4: 129,449,433 (GRCm39) |
E299G |
probably damaging |
Het |
| Lonrf1 |
A |
G |
8: 36,689,864 (GRCm39) |
V703A |
probably damaging |
Het |
| Ly6f |
T |
C |
15: 75,143,526 (GRCm39) |
C78R |
probably damaging |
Het |
| Mapkap1 |
C |
T |
2: 34,423,793 (GRCm39) |
|
probably benign |
Het |
| Mast1 |
T |
A |
8: 85,639,718 (GRCm39) |
I1204F |
probably damaging |
Het |
| Mbd6 |
C |
T |
10: 127,121,742 (GRCm39) |
|
probably benign |
Het |
| Mef2c |
A |
T |
13: 83,741,020 (GRCm39) |
T60S |
probably damaging |
Het |
| Mgat4c |
C |
T |
10: 102,224,980 (GRCm39) |
T398I |
probably damaging |
Het |
| Mmp12 |
C |
A |
9: 7,350,016 (GRCm39) |
H102Q |
probably damaging |
Het |
| Mmp20 |
G |
A |
9: 7,645,374 (GRCm39) |
G308E |
probably damaging |
Het |
| Mms19 |
A |
T |
19: 41,943,285 (GRCm39) |
L395Q |
probably damaging |
Het |
| Mus81 |
A |
G |
19: 5,537,959 (GRCm39) |
|
probably benign |
Het |
| Mypn |
C |
T |
10: 63,028,982 (GRCm39) |
R27H |
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,689,161 (GRCm39) |
E372G |
probably damaging |
Het |
| Ncoa1 |
T |
A |
12: 4,389,105 (GRCm39) |
I57F |
probably damaging |
Het |
| Ncstn |
T |
C |
1: 171,910,159 (GRCm39) |
|
probably benign |
Het |
| Nefm |
C |
T |
14: 68,361,608 (GRCm39) |
D219N |
probably damaging |
Het |
| Notch2 |
C |
T |
3: 98,053,853 (GRCm39) |
T2172I |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 59,024,772 (GRCm39) |
K423* |
probably null |
Het |
| Or51l14 |
A |
G |
7: 103,100,835 (GRCm39) |
N97S |
probably benign |
Het |
| Or5d37 |
A |
C |
2: 87,923,972 (GRCm39) |
S103A |
probably benign |
Het |
| Or5k1 |
T |
C |
16: 58,617,684 (GRCm39) |
N175S |
probably benign |
Het |
| Or9a2 |
A |
T |
6: 41,749,198 (GRCm39) |
C12S |
probably benign |
Het |
| Ostm1 |
T |
A |
10: 42,572,343 (GRCm39) |
M242K |
probably damaging |
Het |
| Oxnad1 |
T |
A |
14: 31,821,437 (GRCm39) |
I154N |
probably damaging |
Het |
| Pcdhb10 |
T |
A |
18: 37,546,152 (GRCm39) |
D409E |
probably damaging |
Het |
| Pdcd11 |
T |
C |
19: 47,113,476 (GRCm39) |
|
probably benign |
Het |
| Peak1 |
C |
A |
9: 56,165,916 (GRCm39) |
V671L |
probably benign |
Het |
| Pex1 |
G |
A |
5: 3,656,444 (GRCm39) |
|
probably null |
Het |
| Plk4 |
T |
A |
3: 40,760,075 (GRCm39) |
F324I |
probably benign |
Het |
| Poglut2 |
C |
T |
1: 44,149,917 (GRCm39) |
W424* |
probably null |
Het |
| Ppfibp1 |
C |
A |
6: 146,920,529 (GRCm39) |
|
probably null |
Het |
| Prcp |
T |
A |
7: 92,568,290 (GRCm39) |
W276R |
probably damaging |
Het |
| Prr14l |
T |
C |
5: 32,987,224 (GRCm39) |
E757G |
probably benign |
Het |
| Prss52 |
T |
A |
14: 64,351,093 (GRCm39) |
Y293N |
probably damaging |
Het |
| Prune2 |
A |
G |
19: 16,984,156 (GRCm39) |
|
probably benign |
Het |
| Ptprk |
G |
C |
10: 28,461,943 (GRCm39) |
A84P |
probably damaging |
Het |
| Ptprk |
C |
T |
10: 28,461,944 (GRCm39) |
A84V |
probably damaging |
Het |
| Rock1 |
A |
G |
18: 10,079,120 (GRCm39) |
L1116P |
possibly damaging |
Het |
| Sdha |
A |
T |
13: 74,475,452 (GRCm39) |
F526Y |
probably benign |
Het |
| Sema4b |
T |
C |
7: 79,869,954 (GRCm39) |
F414S |
probably damaging |
Het |
| Serpina12 |
T |
C |
12: 104,001,960 (GRCm39) |
D252G |
probably damaging |
Het |
| Siglecg |
C |
T |
7: 43,060,550 (GRCm39) |
A310V |
probably benign |
Het |
| Slc30a8 |
A |
G |
15: 52,188,966 (GRCm39) |
I194V |
probably benign |
Het |
| Spred3 |
A |
G |
7: 28,862,400 (GRCm39) |
S148P |
probably damaging |
Het |
| Taf9b |
A |
G |
X: 105,262,014 (GRCm39) |
S58P |
probably damaging |
Het |
| Tgm4 |
A |
T |
9: 122,891,484 (GRCm39) |
Y109F |
probably benign |
Het |
| Tmprss11c |
T |
G |
5: 86,385,468 (GRCm39) |
|
probably benign |
Het |
| Tmtc3 |
A |
T |
10: 100,307,266 (GRCm39) |
V246D |
probably damaging |
Het |
| Tnip1 |
C |
T |
11: 54,828,820 (GRCm39) |
G116R |
probably damaging |
Het |
| Tpr |
A |
G |
1: 150,303,992 (GRCm39) |
E1455G |
possibly damaging |
Het |
| Ttc3 |
T |
A |
16: 94,232,863 (GRCm39) |
L986* |
probably null |
Het |
| Txndc15 |
A |
G |
13: 55,872,436 (GRCm39) |
I275V |
possibly damaging |
Het |
| Ugt2b1 |
T |
A |
5: 87,074,315 (GRCm39) |
I15L |
probably benign |
Het |
| Upf2 |
T |
C |
2: 5,962,445 (GRCm39) |
V49A |
possibly damaging |
Het |
| Vmn1r117 |
G |
A |
7: 20,617,371 (GRCm39) |
P226S |
probably benign |
Het |
| Vmn2r28 |
A |
T |
7: 5,493,456 (GRCm39) |
H163Q |
probably benign |
Het |
| Vstm2a |
T |
A |
11: 16,213,240 (GRCm39) |
S208R |
probably damaging |
Het |
| Zfp346 |
T |
A |
13: 55,260,910 (GRCm39) |
C79* |
probably null |
Het |
| Zfp628 |
A |
T |
7: 4,924,615 (GRCm39) |
T946S |
probably benign |
Het |
|
| Other mutations in Ascc3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00264:Ascc3
|
APN |
10 |
50,590,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00690:Ascc3
|
APN |
10 |
50,576,039 (GRCm39) |
nonsense |
probably null |
|
|
IGL00897:Ascc3
|
APN |
10 |
50,604,187 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01077:Ascc3
|
APN |
10 |
50,525,413 (GRCm39) |
splice site |
probably benign |
|
|
IGL01124:Ascc3
|
APN |
10 |
50,608,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01555:Ascc3
|
APN |
10 |
50,626,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02019:Ascc3
|
APN |
10 |
50,566,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02161:Ascc3
|
APN |
10 |
50,726,623 (GRCm39) |
nonsense |
probably null |
|
|
IGL02247:Ascc3
|
APN |
10 |
50,526,686 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02318:Ascc3
|
APN |
10 |
50,604,250 (GRCm39) |
nonsense |
probably null |
|
|
IGL02428:Ascc3
|
APN |
10 |
50,721,791 (GRCm39) |
nonsense |
probably null |
|
|
IGL02432:Ascc3
|
APN |
10 |
50,576,589 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02449:Ascc3
|
APN |
10 |
50,576,695 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02640:Ascc3
|
APN |
10 |
50,643,470 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02673:Ascc3
|
APN |
10 |
50,536,769 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03144:Ascc3
|
APN |
10 |
50,643,539 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03161:Ascc3
|
APN |
10 |
50,494,168 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03218:Ascc3
|
APN |
10 |
50,699,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
algorithm
|
UTSW |
10 |
50,594,472 (GRCm39) |
missense |
probably damaging |
0.97 |
|
heuristic
|
UTSW |
10 |
50,718,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
network
|
UTSW |
10 |
50,630,175 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0045:Ascc3
|
UTSW |
10 |
50,594,498 (GRCm39) |
nonsense |
probably null |
|
|
R0045:Ascc3
|
UTSW |
10 |
50,594,498 (GRCm39) |
nonsense |
probably null |
|
|
R0131:Ascc3
|
UTSW |
10 |
50,611,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0131:Ascc3
|
UTSW |
10 |
50,611,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0132:Ascc3
|
UTSW |
10 |
50,611,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0149:Ascc3
|
UTSW |
10 |
50,484,089 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0165:Ascc3
|
UTSW |
10 |
50,718,223 (GRCm39) |
splice site |
probably null |
|
|
R0255:Ascc3
|
UTSW |
10 |
50,521,154 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0310:Ascc3
|
UTSW |
10 |
50,625,022 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0314:Ascc3
|
UTSW |
10 |
50,514,095 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0362:Ascc3
|
UTSW |
10 |
50,625,051 (GRCm39) |
splice site |
probably benign |
|
|
R0418:Ascc3
|
UTSW |
10 |
50,625,022 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0419:Ascc3
|
UTSW |
10 |
50,625,022 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0421:Ascc3
|
UTSW |
10 |
50,625,022 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0744:Ascc3
|
UTSW |
10 |
50,721,762 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0833:Ascc3
|
UTSW |
10 |
50,721,762 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1231:Ascc3
|
UTSW |
10 |
50,699,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1264:Ascc3
|
UTSW |
10 |
50,518,615 (GRCm39) |
splice site |
probably benign |
|
|
R1302:Ascc3
|
UTSW |
10 |
50,480,890 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R1751:Ascc3
|
UTSW |
10 |
50,594,472 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1767:Ascc3
|
UTSW |
10 |
50,594,472 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1769:Ascc3
|
UTSW |
10 |
50,576,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1840:Ascc3
|
UTSW |
10 |
50,566,257 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1855:Ascc3
|
UTSW |
10 |
50,494,018 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1953:Ascc3
|
UTSW |
10 |
50,721,726 (GRCm39) |
missense |
probably benign |
|
|
R1976:Ascc3
|
UTSW |
10 |
50,525,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Ascc3
|
UTSW |
10 |
50,493,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2013:Ascc3
|
UTSW |
10 |
50,525,908 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2017:Ascc3
|
UTSW |
10 |
50,566,307 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2040:Ascc3
|
UTSW |
10 |
50,604,227 (GRCm39) |
missense |
probably benign |
|
|
R2043:Ascc3
|
UTSW |
10 |
50,576,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2165:Ascc3
|
UTSW |
10 |
50,597,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2226:Ascc3
|
UTSW |
10 |
50,630,148 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2310:Ascc3
|
UTSW |
10 |
50,624,988 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2405:Ascc3
|
UTSW |
10 |
50,607,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2424:Ascc3
|
UTSW |
10 |
50,494,297 (GRCm39) |
missense |
probably benign |
0.14 |
|
R3410:Ascc3
|
UTSW |
10 |
50,576,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3617:Ascc3
|
UTSW |
10 |
50,494,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3771:Ascc3
|
UTSW |
10 |
50,596,814 (GRCm39) |
splice site |
probably benign |
|
|
R3783:Ascc3
|
UTSW |
10 |
50,604,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3891:Ascc3
|
UTSW |
10 |
50,718,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3892:Ascc3
|
UTSW |
10 |
50,718,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4435:Ascc3
|
UTSW |
10 |
50,597,981 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4509:Ascc3
|
UTSW |
10 |
50,718,339 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4520:Ascc3
|
UTSW |
10 |
50,536,766 (GRCm39) |
missense |
probably benign |
|
|
R4521:Ascc3
|
UTSW |
10 |
50,536,766 (GRCm39) |
missense |
probably benign |
|
|
R4522:Ascc3
|
UTSW |
10 |
50,536,766 (GRCm39) |
missense |
probably benign |
|
|
R4524:Ascc3
|
UTSW |
10 |
50,536,766 (GRCm39) |
missense |
probably benign |
|
|
R4581:Ascc3
|
UTSW |
10 |
50,587,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Ascc3
|
UTSW |
10 |
50,596,760 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4704:Ascc3
|
UTSW |
10 |
50,535,110 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4768:Ascc3
|
UTSW |
10 |
50,576,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4823:Ascc3
|
UTSW |
10 |
50,589,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Ascc3
|
UTSW |
10 |
50,625,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Ascc3
|
UTSW |
10 |
50,699,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5001:Ascc3
|
UTSW |
10 |
50,699,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Ascc3
|
UTSW |
10 |
50,514,059 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5263:Ascc3
|
UTSW |
10 |
50,592,757 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5302:Ascc3
|
UTSW |
10 |
50,583,873 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5436:Ascc3
|
UTSW |
10 |
50,535,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5455:Ascc3
|
UTSW |
10 |
50,725,679 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5474:Ascc3
|
UTSW |
10 |
50,725,634 (GRCm39) |
missense |
probably benign |
0.25 |
|
R5744:Ascc3
|
UTSW |
10 |
50,586,977 (GRCm39) |
missense |
probably benign |
|
|
R5781:Ascc3
|
UTSW |
10 |
50,514,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5850:Ascc3
|
UTSW |
10 |
50,587,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5867:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R5868:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R5869:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R6031:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R6031:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R6032:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R6032:Ascc3
|
UTSW |
10 |
50,718,279 (GRCm39) |
nonsense |
probably null |
|
|
R6109:Ascc3
|
UTSW |
10 |
50,525,343 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6122:Ascc3
|
UTSW |
10 |
50,494,021 (GRCm39) |
missense |
probably benign |
|
|
R6128:Ascc3
|
UTSW |
10 |
50,526,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6351:Ascc3
|
UTSW |
10 |
50,596,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6368:Ascc3
|
UTSW |
10 |
50,576,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6369:Ascc3
|
UTSW |
10 |
50,576,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Ascc3
|
UTSW |
10 |
50,721,676 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6472:Ascc3
|
UTSW |
10 |
50,596,783 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6474:Ascc3
|
UTSW |
10 |
50,624,932 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6480:Ascc3
|
UTSW |
10 |
50,587,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6553:Ascc3
|
UTSW |
10 |
50,718,273 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6572:Ascc3
|
UTSW |
10 |
50,566,343 (GRCm39) |
nonsense |
probably null |
|
|
R6585:Ascc3
|
UTSW |
10 |
50,718,273 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6656:Ascc3
|
UTSW |
10 |
50,526,021 (GRCm39) |
nonsense |
probably null |
|
|
R6669:Ascc3
|
UTSW |
10 |
50,716,469 (GRCm39) |
missense |
probably benign |
|
|
R6675:Ascc3
|
UTSW |
10 |
50,626,659 (GRCm39) |
nonsense |
probably null |
|
|
R6790:Ascc3
|
UTSW |
10 |
50,521,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6856:Ascc3
|
UTSW |
10 |
50,625,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6862:Ascc3
|
UTSW |
10 |
50,725,742 (GRCm39) |
missense |
probably null |
0.51 |
|
R6919:Ascc3
|
UTSW |
10 |
50,521,849 (GRCm39) |
nonsense |
probably null |
|
|
R6936:Ascc3
|
UTSW |
10 |
50,606,057 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6953:Ascc3
|
UTSW |
10 |
50,521,762 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6957:Ascc3
|
UTSW |
10 |
50,604,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7022:Ascc3
|
UTSW |
10 |
50,592,725 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7050:Ascc3
|
UTSW |
10 |
50,716,446 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7358:Ascc3
|
UTSW |
10 |
50,590,448 (GRCm39) |
nonsense |
probably null |
|
|
R7479:Ascc3
|
UTSW |
10 |
50,525,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7538:Ascc3
|
UTSW |
10 |
50,721,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7838:Ascc3
|
UTSW |
10 |
50,604,393 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8021:Ascc3
|
UTSW |
10 |
50,607,744 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8134:Ascc3
|
UTSW |
10 |
50,643,554 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8252:Ascc3
|
UTSW |
10 |
50,518,706 (GRCm39) |
missense |
probably benign |
|
|
R8348:Ascc3
|
UTSW |
10 |
50,494,173 (GRCm39) |
missense |
probably benign |
|
|
R8351:Ascc3
|
UTSW |
10 |
50,725,693 (GRCm39) |
missense |
probably benign |
|
|
R8356:Ascc3
|
UTSW |
10 |
50,526,003 (GRCm39) |
missense |
probably benign |
0.38 |
|
R8362:Ascc3
|
UTSW |
10 |
50,518,692 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8395:Ascc3
|
UTSW |
10 |
50,525,400 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8448:Ascc3
|
UTSW |
10 |
50,494,173 (GRCm39) |
missense |
probably benign |
|
|
R8957:Ascc3
|
UTSW |
10 |
50,576,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9004:Ascc3
|
UTSW |
10 |
50,718,276 (GRCm39) |
missense |
probably benign |
|
|
R9133:Ascc3
|
UTSW |
10 |
50,630,175 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9200:Ascc3
|
UTSW |
10 |
50,521,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9328:Ascc3
|
UTSW |
10 |
50,535,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9377:Ascc3
|
UTSW |
10 |
50,608,858 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9412:Ascc3
|
UTSW |
10 |
50,525,230 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9576:Ascc3
|
UTSW |
10 |
50,494,254 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9796:Ascc3
|
UTSW |
10 |
50,608,801 (GRCm39) |
nonsense |
probably null |
|
|
X0021:Ascc3
|
UTSW |
10 |
50,576,686 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
X0025:Ascc3
|
UTSW |
10 |
50,526,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0026:Ascc3
|
UTSW |
10 |
50,608,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ascc3
|
UTSW |
10 |
50,594,517 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCTTCCCACTTGAAGCCACAGATATG -3'
(R):5'- GTAGCACAATGGACTCCTTGTTCCC -3'
Sequencing Primer
(F):5'- TCTCCTGATGCCAGGAAATG -3'
(R):5'- GACTCCTTGTTCCCTCGTATTTTG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation