Incidental Mutation 'IGL03350:Hydin'
ID 419683
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Hydin
Ensembl Gene ENSMUSG00000059854
Gene Name HYDIN, axonemal central pair apparatus protein
Synonyms hy-3, hyrh, hy3, 1700034M11Rik, 4930545D19Rik
Accession Numbers
Essential gene? Probably essential (E-score: 0.757) question?
Stock # IGL03350
Quality Score
Status
Chromosome 8
Chromosomal Location 110266977-110610253 bp(+) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) A to G at 110312224 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Histidine to Arginine at position 198 (H198R)
Ref Sequence ENSEMBL: ENSMUSP00000046204 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000043141]
AlphaFold no structure available at present
Predicted Effect possibly damaging
Transcript: ENSMUST00000043141
AA Change: H198R

PolyPhen 2 Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000046204
Gene: ENSMUSG00000059854
AA Change: H198R

DomainStartEndE-ValueType
Pfam:Motile_Sperm 246 325 5.6e-8 PFAM
Pfam:ASH 559 659 9.4e-17 PFAM
low complexity region 788 798 N/A INTRINSIC
Pfam:PapD-like 848 906 1.2e-6 PFAM
low complexity region 998 1024 N/A INTRINSIC
low complexity region 1279 1292 N/A INTRINSIC
internal_repeat_6 1317 1549 5.96e-5 PROSPERO
internal_repeat_5 1355 1502 3.23e-5 PROSPERO
low complexity region 1574 1590 N/A INTRINSIC
internal_repeat_4 1712 1940 5.14e-6 PROSPERO
coiled coil region 1947 1977 N/A INTRINSIC
low complexity region 2009 2020 N/A INTRINSIC
low complexity region 2034 2049 N/A INTRINSIC
SCOP:d1eq1a_ 2305 2403 3e-4 SMART
low complexity region 2404 2419 N/A INTRINSIC
coiled coil region 2543 2588 N/A INTRINSIC
low complexity region 2636 2656 N/A INTRINSIC
internal_repeat_7 2772 3008 8.1e-5 PROSPERO
low complexity region 3660 3670 N/A INTRINSIC
low complexity region 3919 3934 N/A INTRINSIC
internal_repeat_5 4046 4190 3.23e-5 PROSPERO
internal_repeat_2 4106 4251 6.03e-7 PROSPERO
internal_repeat_4 4317 4532 5.14e-6 PROSPERO
internal_repeat_3 4403 4689 2.05e-6 PROSPERO
internal_repeat_2 4549 4697 6.03e-7 PROSPERO
low complexity region 4951 4964 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000212218
Coding Region Coverage
Validation Efficiency
MGI Phenotype Strain: 1856913; 3801608
Lethality: D28-D42
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that may be involved in cilia motility. Mutations in this gene cause of autosomal recessive primary ciliary dyskinesia-5, a disorder characterized by the accumulation of cerebrospinal fluid within the ventricles of the brain. A duplicate copy of this gene has been found in humans on chromosome 1. [provided by RefSeq, Jan 2013]
PHENOTYPE: Mice homozygous for a mutation in this gene develop hydrocephaly after birth. Symptoms develop after 3-5 days. Affected animals usually die before 2 months of age. [provided by MGI curators]
Allele List at MGI

All alleles(7) : Targeted(1) Gene trapped(3) Transgenic(1) Spontaneous(2)

Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam26a A T 8: 43,569,552 (GRCm38) Y300* probably null Het
Adgre1 T A 17: 57,401,908 (GRCm38) V33E probably benign Het
AI987944 A G 7: 41,393,237 (GRCm38) probably benign Het
Atp4a T C 7: 30,720,867 (GRCm38) L813P probably damaging Het
Blmh A G 11: 76,971,948 (GRCm38) N396D probably damaging Het
Brat1 T C 5: 140,705,995 (GRCm38) L9P probably damaging Het
Ccdc171 T C 4: 83,681,378 (GRCm38) I810T possibly damaging Het
Clec2m C A 6: 129,331,023 (GRCm38) V28L probably benign Het
Cyp2a22 T C 7: 26,934,854 (GRCm38) T292A possibly damaging Het
Ecm2 C T 13: 49,520,944 (GRCm38) T280I probably benign Het
Fa2h C T 8: 111,349,296 (GRCm38) V232I probably benign Het
Fbxw24 T C 9: 109,607,013 (GRCm38) D317G probably damaging Het
Flt4 C A 11: 49,634,793 (GRCm38) S722* probably null Het
Fryl T C 5: 73,133,306 (GRCm38) Q85R probably damaging Het
Gm3239 A G 14: 4,667,115 (GRCm38) R188G possibly damaging Het
Hspa13 A T 16: 75,757,829 (GRCm38) S456R probably damaging Het
Htr1b T C 9: 81,632,122 (GRCm38) Y144C probably damaging Het
Krt78 A T 15: 101,946,517 (GRCm38) M953K probably benign Het
Lgr5 G T 10: 115,471,988 (GRCm38) T255K probably damaging Het
Lrp2 T A 2: 69,438,453 (GRCm38) D4162V probably damaging Het
Map3k2 A G 18: 32,212,148 (GRCm38) D342G probably damaging Het
Miip A G 4: 147,862,522 (GRCm38) V258A probably benign Het
Muc6 T C 7: 141,652,059 (GRCm38) H52R probably damaging Het
Nfs1 T C 2: 156,127,740 (GRCm38) E329G probably benign Het
Npsr1 T C 9: 24,098,309 (GRCm38) V37A probably benign Het
Or1ak2 T C 2: 36,937,583 (GRCm38) Y155H probably damaging Het
Or1e17 A T 11: 73,940,838 (GRCm38) L197F probably damaging Het
Or5aq1b A C 2: 87,071,560 (GRCm38) D191E probably damaging Het
Pex16 T A 2: 92,377,497 (GRCm38) M98K probably damaging Het
Pla2r1 C T 2: 60,455,173 (GRCm38) C699Y probably damaging Het
Plcd4 A T 1: 74,549,301 (GRCm38) D103V probably damaging Het
Pnpla1 A G 17: 28,876,992 (GRCm38) D129G probably damaging Het
Rad23a T C 8: 84,837,479 (GRCm38) E265G possibly damaging Het
Rbm11 C T 16: 75,600,808 (GRCm38) P209S probably benign Het
Ribc2 T A 15: 85,135,502 (GRCm38) W162R probably damaging Het
Rnf4 A G 5: 34,346,860 (GRCm38) E32G possibly damaging Het
Rpe65 A T 3: 159,614,517 (GRCm38) S269C possibly damaging Het
Slc7a14 T A 3: 31,237,409 (GRCm38) Y240F probably benign Het
Sorbs2 C T 8: 45,805,807 (GRCm38) P1047L probably damaging Het
Ttn T C 2: 76,749,822 (GRCm38) I23576V probably damaging Het
Usp24 T G 4: 106,371,079 (GRCm38) Y780* probably null Het
Wee2 T C 6: 40,449,731 (GRCm38) S145P probably damaging Het
Zcchc7 A G 4: 44,931,188 (GRCm38) T126A probably benign Het
Zpld1 A G 16: 55,241,329 (GRCm38) probably benign Het
Zup1 G A 10: 33,928,111 (GRCm38) R456C probably benign Het
Other mutations in Hydin
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00338:Hydin APN 8 110,569,802 (GRCm38) missense possibly damaging 0.69
IGL00432:Hydin APN 8 110,601,252 (GRCm38) missense probably damaging 0.98
IGL01025:Hydin APN 8 110,326,401 (GRCm38) missense probably benign 0.38
IGL01140:Hydin APN 8 110,398,062 (GRCm38) missense probably benign 0.14
IGL01317:Hydin APN 8 110,326,446 (GRCm38) missense probably damaging 0.98
IGL01473:Hydin APN 8 110,312,160 (GRCm38) missense probably benign 0.08
IGL01473:Hydin APN 8 110,354,953 (GRCm38) missense probably damaging 1.00
IGL01610:Hydin APN 8 110,557,713 (GRCm38) missense probably benign 0.00
IGL01685:Hydin APN 8 110,355,033 (GRCm38) nonsense probably null
IGL01734:Hydin APN 8 110,490,789 (GRCm38) nonsense probably null
IGL01743:Hydin APN 8 110,592,776 (GRCm38) missense possibly damaging 0.94
IGL01829:Hydin APN 8 110,589,522 (GRCm38) missense possibly damaging 0.68
IGL01919:Hydin APN 8 110,519,174 (GRCm38) missense possibly damaging 0.89
IGL01946:Hydin APN 8 110,490,718 (GRCm38) missense possibly damaging 0.91
IGL01983:Hydin APN 8 110,514,895 (GRCm38) missense probably benign 0.02
IGL02122:Hydin APN 8 110,494,415 (GRCm38) missense possibly damaging 0.86
IGL02140:Hydin APN 8 110,566,938 (GRCm38) missense probably benign
IGL02158:Hydin APN 8 110,609,966 (GRCm38) missense possibly damaging 0.89
IGL02167:Hydin APN 8 110,418,423 (GRCm38) missense possibly damaging 0.96
IGL02171:Hydin APN 8 110,451,958 (GRCm38) nonsense probably null
IGL02185:Hydin APN 8 110,506,476 (GRCm38) missense possibly damaging 0.86
IGL02517:Hydin APN 8 110,566,972 (GRCm38) missense probably benign 0.01
IGL02639:Hydin APN 8 110,538,449 (GRCm38) missense probably benign 0.01
IGL02644:Hydin APN 8 110,538,468 (GRCm38) missense probably damaging 1.00
IGL02652:Hydin APN 8 110,589,522 (GRCm38) missense possibly damaging 0.68
IGL02658:Hydin APN 8 110,413,276 (GRCm38) missense possibly damaging 0.86
IGL02706:Hydin APN 8 110,410,566 (GRCm38) missense probably damaging 0.99
IGL02892:Hydin APN 8 110,598,959 (GRCm38) missense possibly damaging 0.89
IGL02947:Hydin APN 8 110,418,462 (GRCm38) missense probably damaging 0.96
IGL03136:Hydin APN 8 110,418,524 (GRCm38) missense probably benign 0.22
IGL03248:Hydin APN 8 110,595,289 (GRCm38) missense probably damaging 0.97
IGL03251:Hydin APN 8 110,490,596 (GRCm38) missense probably damaging 1.00
IGL03366:Hydin APN 8 110,267,363 (GRCm38) missense unknown
IGL03404:Hydin APN 8 110,569,777 (GRCm38) missense probably benign 0.06
Franz_joseph UTSW 8 110,601,318 (GRCm38) missense probably damaging 1.00
jahreszeiten UTSW 8 110,569,359 (GRCm38) missense probably damaging 1.00
maria UTSW 8 110,509,127 (GRCm38) splice site probably benign
schoepfung UTSW 8 110,600,245 (GRCm38) missense possibly damaging 0.68
surprise UTSW 8 110,528,016 (GRCm38) missense probably benign
teresa UTSW 8 110,609,671 (GRCm38) missense possibly damaging 0.79
BB001:Hydin UTSW 8 110,418,471 (GRCm38) missense possibly damaging 0.93
BB004:Hydin UTSW 8 110,580,844 (GRCm38) missense possibly damaging 0.89
BB011:Hydin UTSW 8 110,418,471 (GRCm38) missense possibly damaging 0.93
BB014:Hydin UTSW 8 110,580,844 (GRCm38) missense possibly damaging 0.89
P0005:Hydin UTSW 8 110,494,289 (GRCm38) critical splice acceptor site probably null
R0099:Hydin UTSW 8 110,589,561 (GRCm38) missense probably damaging 1.00
R0125:Hydin UTSW 8 110,462,531 (GRCm38) missense probably benign 0.12
R0157:Hydin UTSW 8 110,300,010 (GRCm38) missense possibly damaging 0.86
R0241:Hydin UTSW 8 110,398,023 (GRCm38) missense probably benign 0.04
R0241:Hydin UTSW 8 110,398,023 (GRCm38) missense probably benign 0.04
R0255:Hydin UTSW 8 110,565,018 (GRCm38) missense probably benign 0.00
R0352:Hydin UTSW 8 110,569,901 (GRCm38) critical splice donor site probably null
R0379:Hydin UTSW 8 110,509,127 (GRCm38) splice site probably benign
R0468:Hydin UTSW 8 110,413,223 (GRCm38) missense possibly damaging 0.96
R0477:Hydin UTSW 8 110,418,498 (GRCm38) missense probably damaging 1.00
R0479:Hydin UTSW 8 110,599,088 (GRCm38) missense probably damaging 1.00
R0539:Hydin UTSW 8 110,523,072 (GRCm38) missense probably benign
R0550:Hydin UTSW 8 110,587,775 (GRCm38) missense probably benign 0.01
R0571:Hydin UTSW 8 110,514,103 (GRCm38) splice site probably null
R0606:Hydin UTSW 8 110,549,798 (GRCm38) splice site probably benign
R0789:Hydin UTSW 8 110,566,971 (GRCm38) missense possibly damaging 0.53
R0849:Hydin UTSW 8 110,598,984 (GRCm38) missense probably damaging 1.00
R0946:Hydin UTSW 8 110,531,053 (GRCm38) missense probably benign 0.25
R1201:Hydin UTSW 8 110,569,855 (GRCm38) missense probably benign 0.01
R1375:Hydin UTSW 8 110,506,222 (GRCm38) critical splice donor site probably null
R1385:Hydin UTSW 8 110,523,204 (GRCm38) missense probably benign 0.40
R1411:Hydin UTSW 8 110,575,031 (GRCm38) missense probably benign 0.04
R1437:Hydin UTSW 8 110,581,985 (GRCm38) nonsense probably null
R1447:Hydin UTSW 8 110,523,166 (GRCm38) missense probably damaging 1.00
R1448:Hydin UTSW 8 110,446,585 (GRCm38) missense probably benign 0.27
R1466:Hydin UTSW 8 110,532,953 (GRCm38) missense possibly damaging 0.47
R1466:Hydin UTSW 8 110,532,953 (GRCm38) missense possibly damaging 0.47
R1523:Hydin UTSW 8 110,533,271 (GRCm38) missense probably benign 0.05
R1544:Hydin UTSW 8 110,574,854 (GRCm38) missense probably benign 0.30
R1581:Hydin UTSW 8 110,410,460 (GRCm38) missense probably benign
R1584:Hydin UTSW 8 110,580,815 (GRCm38) missense probably benign 0.27
R1598:Hydin UTSW 8 110,410,674 (GRCm38) missense possibly damaging 0.96
R1633:Hydin UTSW 8 110,506,982 (GRCm38) missense probably benign 0.10
R1777:Hydin UTSW 8 110,589,571 (GRCm38) missense probably benign 0.14
R1817:Hydin UTSW 8 110,532,827 (GRCm38) missense probably benign 0.00
R1828:Hydin UTSW 8 110,510,894 (GRCm38) missense probably benign 0.03
R1837:Hydin UTSW 8 110,569,625 (GRCm38) missense probably benign 0.20
R1848:Hydin UTSW 8 110,569,808 (GRCm38) missense probably benign 0.19
R1869:Hydin UTSW 8 110,500,705 (GRCm38) missense possibly damaging 0.94
R1909:Hydin UTSW 8 110,587,772 (GRCm38) missense probably damaging 1.00
R1928:Hydin UTSW 8 110,502,947 (GRCm38) missense possibly damaging 0.93
R1950:Hydin UTSW 8 110,609,987 (GRCm38) missense possibly damaging 0.64
R2095:Hydin UTSW 8 110,462,657 (GRCm38) missense probably damaging 0.96
R2172:Hydin UTSW 8 110,582,049 (GRCm38) missense probably benign 0.42
R2217:Hydin UTSW 8 110,418,506 (GRCm38) missense probably benign
R2248:Hydin UTSW 8 110,578,203 (GRCm38) missense probably benign 0.09
R2272:Hydin UTSW 8 110,309,132 (GRCm38) missense probably benign 0.01
R2294:Hydin UTSW 8 110,299,959 (GRCm38) missense probably damaging 0.99
R2315:Hydin UTSW 8 110,398,044 (GRCm38) missense probably benign 0.01
R2330:Hydin UTSW 8 110,565,009 (GRCm38) missense probably benign 0.01
R2374:Hydin UTSW 8 110,565,148 (GRCm38) missense probably damaging 1.00
R2446:Hydin UTSW 8 110,587,715 (GRCm38) missense possibly damaging 0.82
R2484:Hydin UTSW 8 110,513,115 (GRCm38) missense possibly damaging 0.76
R2698:Hydin UTSW 8 110,609,929 (GRCm38) missense possibly damaging 0.70
R2843:Hydin UTSW 8 110,519,114 (GRCm38) missense probably benign
R2844:Hydin UTSW 8 110,519,114 (GRCm38) missense probably benign
R2846:Hydin UTSW 8 110,519,114 (GRCm38) missense probably benign
R2882:Hydin UTSW 8 110,566,923 (GRCm38) missense possibly damaging 0.92
R2937:Hydin UTSW 8 110,404,295 (GRCm38) missense possibly damaging 0.88
R3031:Hydin UTSW 8 110,603,216 (GRCm38) missense possibly damaging 0.83
R3038:Hydin UTSW 8 110,582,689 (GRCm38) missense probably damaging 1.00
R3121:Hydin UTSW 8 110,506,506 (GRCm38) missense probably benign
R3157:Hydin UTSW 8 110,267,373 (GRCm38) missense unknown
R3547:Hydin UTSW 8 110,582,067 (GRCm38) missense possibly damaging 0.85
R3696:Hydin UTSW 8 110,603,279 (GRCm38) missense probably damaging 1.00
R3850:Hydin UTSW 8 110,563,929 (GRCm38) missense probably damaging 0.99
R3896:Hydin UTSW 8 110,509,079 (GRCm38) missense possibly damaging 0.93
R3983:Hydin UTSW 8 110,392,325 (GRCm38) missense probably damaging 1.00
R4031:Hydin UTSW 8 110,610,047 (GRCm38) missense probably benign 0.30
R4072:Hydin UTSW 8 110,505,256 (GRCm38) missense possibly damaging 0.68
R4095:Hydin UTSW 8 110,541,547 (GRCm38) missense probably damaging 0.98
R4176:Hydin UTSW 8 110,593,820 (GRCm38) missense probably benign 0.00
R4213:Hydin UTSW 8 110,456,507 (GRCm38) missense possibly damaging 0.91
R4412:Hydin UTSW 8 110,415,736 (GRCm38) missense probably damaging 0.99
R4471:Hydin UTSW 8 110,587,132 (GRCm38) missense probably damaging 1.00
R4474:Hydin UTSW 8 110,563,865 (GRCm38) missense probably benign 0.11
R4495:Hydin UTSW 8 110,595,402 (GRCm38) missense probably damaging 0.99
R4508:Hydin UTSW 8 110,519,254 (GRCm38) missense possibly damaging 0.91
R4578:Hydin UTSW 8 110,267,339 (GRCm38) missense unknown
R4583:Hydin UTSW 8 110,595,225 (GRCm38) missense probably benign 0.36
R4600:Hydin UTSW 8 110,566,950 (GRCm38) missense probably benign 0.04
R4681:Hydin UTSW 8 110,506,471 (GRCm38) missense possibly damaging 0.85
R4685:Hydin UTSW 8 110,462,522 (GRCm38) missense probably damaging 0.99
R4689:Hydin UTSW 8 110,595,414 (GRCm38) missense probably benign 0.18
R4735:Hydin UTSW 8 110,555,632 (GRCm38) critical splice donor site probably null
R4736:Hydin UTSW 8 110,523,208 (GRCm38) missense probably benign 0.02
R4740:Hydin UTSW 8 110,446,439 (GRCm38) missense probably benign 0.06
R4771:Hydin UTSW 8 110,532,883 (GRCm38) missense probably benign
R4777:Hydin UTSW 8 110,410,464 (GRCm38) missense probably damaging 0.98
R4859:Hydin UTSW 8 110,506,494 (GRCm38) missense possibly damaging 0.93
R4911:Hydin UTSW 8 110,595,438 (GRCm38) missense probably benign 0.01
R4964:Hydin UTSW 8 110,490,673 (GRCm38) missense possibly damaging 0.86
R4965:Hydin UTSW 8 110,398,095 (GRCm38) missense probably benign
R4989:Hydin UTSW 8 110,563,922 (GRCm38) missense possibly damaging 0.84
R4995:Hydin UTSW 8 110,569,642 (GRCm38) missense probably damaging 0.97
R5059:Hydin UTSW 8 110,505,769 (GRCm38) missense probably damaging 0.96
R5071:Hydin UTSW 8 110,538,473 (GRCm38) missense probably benign 0.03
R5073:Hydin UTSW 8 110,538,473 (GRCm38) missense probably benign 0.03
R5092:Hydin UTSW 8 110,582,668 (GRCm38) missense probably benign 0.16
R5156:Hydin UTSW 8 110,609,701 (GRCm38) missense probably benign 0.00
R5166:Hydin UTSW 8 110,523,142 (GRCm38) missense possibly damaging 0.89
R5189:Hydin UTSW 8 110,413,211 (GRCm38) critical splice acceptor site probably null
R5243:Hydin UTSW 8 110,505,748 (GRCm38) missense possibly damaging 0.92
R5244:Hydin UTSW 8 110,532,819 (GRCm38) missense possibly damaging 0.77
R5256:Hydin UTSW 8 110,587,223 (GRCm38) missense possibly damaging 0.92
R5266:Hydin UTSW 8 110,334,784 (GRCm38) missense possibly damaging 0.87
R5283:Hydin UTSW 8 110,451,980 (GRCm38) missense possibly damaging 0.96
R5343:Hydin UTSW 8 110,485,419 (GRCm38) missense probably benign 0.40
R5359:Hydin UTSW 8 110,538,372 (GRCm38) missense probably benign 0.00
R5390:Hydin UTSW 8 110,595,467 (GRCm38) missense probably benign
R5394:Hydin UTSW 8 110,539,842 (GRCm38) splice site probably null
R5441:Hydin UTSW 8 110,565,109 (GRCm38) missense possibly damaging 0.72
R5461:Hydin UTSW 8 110,519,231 (GRCm38) missense probably damaging 0.96
R5662:Hydin UTSW 8 110,580,709 (GRCm38) missense probably benign 0.02
R5695:Hydin UTSW 8 110,535,283 (GRCm38) missense probably benign 0.35
R5732:Hydin UTSW 8 110,452,058 (GRCm38) missense probably benign 0.03
R5774:Hydin UTSW 8 110,571,915 (GRCm38) nonsense probably null
R5780:Hydin UTSW 8 110,586,080 (GRCm38) missense probably damaging 1.00
R5787:Hydin UTSW 8 110,326,353 (GRCm38) missense probably damaging 0.99
R5802:Hydin UTSW 8 110,452,060 (GRCm38) missense possibly damaging 0.86
R5841:Hydin UTSW 8 110,533,214 (GRCm38) missense possibly damaging 0.76
R5856:Hydin UTSW 8 110,541,842 (GRCm38) missense probably damaging 0.99
R5893:Hydin UTSW 8 110,490,676 (GRCm38) missense probably benign 0.12
R5963:Hydin UTSW 8 110,494,294 (GRCm38) missense possibly damaging 0.93
R6008:Hydin UTSW 8 110,599,085 (GRCm38) missense probably benign 0.02
R6019:Hydin UTSW 8 110,566,620 (GRCm38) missense probably benign
R6038:Hydin UTSW 8 110,599,031 (GRCm38) missense probably benign 0.16
R6038:Hydin UTSW 8 110,599,031 (GRCm38) missense probably benign 0.16
R6133:Hydin UTSW 8 110,601,276 (GRCm38) missense probably benign 0.00
R6135:Hydin UTSW 8 110,462,660 (GRCm38) missense possibly damaging 0.85
R6157:Hydin UTSW 8 110,528,016 (GRCm38) missense probably benign
R6209:Hydin UTSW 8 110,593,802 (GRCm38) missense probably benign 0.05
R6238:Hydin UTSW 8 110,392,111 (GRCm38) splice site probably null
R6293:Hydin UTSW 8 110,597,911 (GRCm38) missense possibly damaging 0.83
R6340:Hydin UTSW 8 110,354,942 (GRCm38) splice site probably null
R6349:Hydin UTSW 8 110,418,459 (GRCm38) nonsense probably null
R6357:Hydin UTSW 8 110,541,657 (GRCm38) missense possibly damaging 0.86
R6385:Hydin UTSW 8 110,312,224 (GRCm38) missense possibly damaging 0.86
R6396:Hydin UTSW 8 110,506,889 (GRCm38) missense probably damaging 0.96
R6466:Hydin UTSW 8 110,506,968 (GRCm38) missense possibly damaging 0.85
R6648:Hydin UTSW 8 110,525,667 (GRCm38) splice site probably null
R6671:Hydin UTSW 8 110,601,318 (GRCm38) missense probably damaging 1.00
R6695:Hydin UTSW 8 110,326,460 (GRCm38) missense probably benign 0.05
R6800:Hydin UTSW 8 110,597,971 (GRCm38) missense probably benign 0.09
R6841:Hydin UTSW 8 110,538,375 (GRCm38) missense probably benign 0.09
R6867:Hydin UTSW 8 110,539,802 (GRCm38) missense probably benign 0.08
R6889:Hydin UTSW 8 110,532,856 (GRCm38) missense possibly damaging 0.79
R6895:Hydin UTSW 8 110,312,251 (GRCm38) missense probably benign 0.00
R6940:Hydin UTSW 8 110,490,611 (GRCm38) missense probably damaging 1.00
R6951:Hydin UTSW 8 110,398,125 (GRCm38) missense probably benign
R6980:Hydin UTSW 8 110,413,284 (GRCm38) missense possibly damaging 0.91
R6981:Hydin UTSW 8 110,531,072 (GRCm38) missense possibly damaging 0.89
R7061:Hydin UTSW 8 110,603,288 (GRCm38) missense possibly damaging 0.90
R7085:Hydin UTSW 8 110,603,330 (GRCm38) missense probably benign 0.03
R7086:Hydin UTSW 8 110,600,245 (GRCm38) missense possibly damaging 0.68
R7110:Hydin UTSW 8 110,354,951 (GRCm38) critical splice acceptor site probably null
R7158:Hydin UTSW 8 110,609,671 (GRCm38) missense possibly damaging 0.79
R7163:Hydin UTSW 8 110,603,336 (GRCm38) missense probably benign 0.25
R7209:Hydin UTSW 8 110,489,792 (GRCm38) nonsense probably null
R7244:Hydin UTSW 8 110,549,675 (GRCm38) missense probably damaging 0.98
R7347:Hydin UTSW 8 110,600,362 (GRCm38) missense probably benign 0.06
R7349:Hydin UTSW 8 110,398,171 (GRCm38) splice site probably null
R7359:Hydin UTSW 8 110,506,101 (GRCm38) missense probably damaging 0.98
R7365:Hydin UTSW 8 110,601,273 (GRCm38) missense probably damaging 1.00
R7365:Hydin UTSW 8 110,557,662 (GRCm38) missense probably damaging 0.99
R7436:Hydin UTSW 8 110,583,914 (GRCm38) missense probably damaging 0.96
R7528:Hydin UTSW 8 110,380,572 (GRCm38) nonsense probably null
R7544:Hydin UTSW 8 110,589,525 (GRCm38) missense probably benign 0.35
R7625:Hydin UTSW 8 110,541,844 (GRCm38) missense probably benign 0.01
R7713:Hydin UTSW 8 110,593,812 (GRCm38) missense possibly damaging 0.69
R7763:Hydin UTSW 8 110,505,843 (GRCm38) missense possibly damaging 0.92
R7771:Hydin UTSW 8 110,565,085 (GRCm38) missense probably damaging 0.97
R7794:Hydin UTSW 8 110,509,083 (GRCm38) missense probably damaging 1.00
R7833:Hydin UTSW 8 110,589,460 (GRCm38) missense probably damaging 0.99
R7894:Hydin UTSW 8 110,513,010 (GRCm38) missense possibly damaging 0.88
R7899:Hydin UTSW 8 110,587,748 (GRCm38) missense probably benign 0.00
R7908:Hydin UTSW 8 110,510,867 (GRCm38) missense probably benign 0.01
R7912:Hydin UTSW 8 110,555,607 (GRCm38) missense possibly damaging 0.68
R7919:Hydin UTSW 8 110,267,339 (GRCm38) missense unknown
R7924:Hydin UTSW 8 110,418,471 (GRCm38) missense possibly damaging 0.93
R7927:Hydin UTSW 8 110,580,844 (GRCm38) missense possibly damaging 0.89
R7970:Hydin UTSW 8 110,309,091 (GRCm38) missense probably damaging 0.99
R7993:Hydin UTSW 8 110,579,632 (GRCm38) missense probably benign
R8011:Hydin UTSW 8 110,583,909 (GRCm38) missense probably damaging 1.00
R8041:Hydin UTSW 8 110,574,994 (GRCm38) missense probably benign 0.02
R8080:Hydin UTSW 8 110,535,231 (GRCm38) missense probably benign 0.32
R8081:Hydin UTSW 8 110,365,469 (GRCm38) missense possibly damaging 0.93
R8095:Hydin UTSW 8 110,569,359 (GRCm38) missense probably damaging 1.00
R8157:Hydin UTSW 8 110,452,036 (GRCm38) missense probably benign 0.33
R8186:Hydin UTSW 8 110,609,645 (GRCm38) missense probably benign 0.14
R8205:Hydin UTSW 8 110,592,638 (GRCm38) missense possibly damaging 0.57
R8263:Hydin UTSW 8 110,452,073 (GRCm38) missense probably benign 0.00
R8288:Hydin UTSW 8 110,507,029 (GRCm38) missense probably damaging 0.96
R8298:Hydin UTSW 8 110,600,383 (GRCm38) missense probably damaging 1.00
R8309:Hydin UTSW 8 110,607,902 (GRCm38) missense probably benign 0.18
R8348:Hydin UTSW 8 110,603,246 (GRCm38) missense possibly damaging 0.68
R8356:Hydin UTSW 8 110,533,124 (GRCm38) missense possibly damaging 0.67
R8406:Hydin UTSW 8 110,609,911 (GRCm38) missense possibly damaging 0.94
R8415:Hydin UTSW 8 110,451,994 (GRCm38) missense probably damaging 1.00
R8417:Hydin UTSW 8 110,569,392 (GRCm38) missense probably benign 0.28
R8432:Hydin UTSW 8 110,597,951 (GRCm38) missense probably benign 0.02
R8437:Hydin UTSW 8 110,462,735 (GRCm38) missense probably damaging 0.96
R8463:Hydin UTSW 8 110,510,921 (GRCm38) missense probably benign 0.22
R8508:Hydin UTSW 8 110,582,018 (GRCm38) missense probably benign 0.00
R8510:Hydin UTSW 8 110,506,570 (GRCm38) missense probably damaging 1.00
R8560:Hydin UTSW 8 110,538,474 (GRCm38) missense probably benign 0.09
R8682:Hydin UTSW 8 110,309,166 (GRCm38) missense probably damaging 0.96
R8697:Hydin UTSW 8 110,532,883 (GRCm38) missense probably benign
R8857:Hydin UTSW 8 110,571,955 (GRCm38) critical splice donor site probably null
R8866:Hydin UTSW 8 110,582,147 (GRCm38) missense possibly damaging 0.89
R8878:Hydin UTSW 8 110,309,088 (GRCm38) missense probably benign 0.12
R8897:Hydin UTSW 8 110,589,480 (GRCm38) missense probably benign
R8987:Hydin UTSW 8 110,513,134 (GRCm38) nonsense probably null
R9072:Hydin UTSW 8 110,267,451 (GRCm38) critical splice donor site probably null
R9073:Hydin UTSW 8 110,267,451 (GRCm38) critical splice donor site probably null
R9102:Hydin UTSW 8 110,508,914 (GRCm38) missense probably benign 0.33
R9224:Hydin UTSW 8 110,532,884 (GRCm38) missense probably benign
R9255:Hydin UTSW 8 110,535,340 (GRCm38) missense probably benign 0.23
R9257:Hydin UTSW 8 110,575,016 (GRCm38) missense probably damaging 0.99
R9261:Hydin UTSW 8 110,267,415 (GRCm38) missense unknown
R9273:Hydin UTSW 8 110,506,948 (GRCm38) missense probably damaging 0.98
R9376:Hydin UTSW 8 110,398,063 (GRCm38) missense possibly damaging 0.70
R9380:Hydin UTSW 8 110,563,872 (GRCm38) missense probably benign 0.07
R9386:Hydin UTSW 8 110,587,730 (GRCm38) missense probably benign
R9406:Hydin UTSW 8 110,587,780 (GRCm38) missense probably null 0.96
R9492:Hydin UTSW 8 110,600,245 (GRCm38) missense possibly damaging 0.68
R9513:Hydin UTSW 8 110,595,482 (GRCm38) missense probably damaging 0.99
R9562:Hydin UTSW 8 110,586,154 (GRCm38) missense probably benign 0.11
R9664:Hydin UTSW 8 110,494,333 (GRCm38) missense probably benign 0.01
R9733:Hydin UTSW 8 110,535,379 (GRCm38) missense probably benign
R9753:Hydin UTSW 8 110,490,766 (GRCm38) missense possibly damaging 0.85
X0063:Hydin UTSW 8 110,551,319 (GRCm38) missense probably damaging 1.00
Z1088:Hydin UTSW 8 110,592,791 (GRCm38) frame shift probably null
Z1088:Hydin UTSW 8 110,586,048 (GRCm38) missense probably benign 0.00
Z1088:Hydin UTSW 8 110,299,973 (GRCm38) missense probably benign 0.12
Z1176:Hydin UTSW 8 110,541,600 (GRCm38) missense possibly damaging 0.65
Z1177:Hydin UTSW 8 110,587,142 (GRCm38) frame shift probably null
Z1177:Hydin UTSW 8 110,450,232 (GRCm38) missense possibly damaging 0.47
Z1177:Hydin UTSW 8 110,380,610 (GRCm38) missense probably damaging 1.00
Z1177:Hydin UTSW 8 110,609,989 (GRCm38) missense probably benign 0.10
Z1188:Hydin UTSW 8 110,415,787 (GRCm38) missense probably benign 0.40
Posted On 2016-08-02