Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03351:Vmn1r29'

419690

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r29

Ensembl Gene

ENSMUSG00000091734

Gene Name

vomeronasal 1 receptor 29

Synonyms

V1rc2

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL03351

Quality Score

Status

Chromosome

Chromosomal Location

58301549-58311685 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 58307750 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Cysteine at position 152 (S152C)

Ref Sequence

ENSEMBL: ENSMUSP00000154278 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000168416] [ENSMUST00000226971] [ENSMUST00000227761] [ENSMUST00000228038] [ENSMUST00000228909]

AlphaFold

Q9EQ41

Predicted Effect

probably damaging
Transcript: ENSMUST00000168416
AA Change: S152C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000129069
Gene: ENSMUSG00000091734
AA Change: S152C

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	1.7e-53	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000226971
AA Change: S152C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Predicted Effect

probably damaging
Transcript: ENSMUST00000227761
AA Change: S152C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Predicted Effect

probably damaging
Transcript: ENSMUST00000228038
AA Change: S152C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Predicted Effect

probably damaging
Transcript: ENSMUST00000228909
AA Change: S152C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930550L24Rik	G	A	X: 58,918,937	V19I	probably benign	Het
4932414N04Rik	T	A	2: 68,731,083	D251E	probably benign	Het
4932415D10Rik	T	C	10: 82,283,567		probably benign	Het
5730460C07Rik	C	T	3: 153,789,958		noncoding transcript	Het
Coch	G	A	12: 51,603,206	R326Q	probably benign	Het
Cpa3	A	G	3: 20,215,962	V366A	probably benign	Het
Csf1r	C	T	18: 61,117,108	Q382*	probably null	Het
Csta1	C	A	16: 36,131,041	G4*	probably null	Het
Cts7	T	C	13: 61,356,603	R49G	probably damaging	Het
Dlg5	A	G	14: 24,170,454	V575A	probably benign	Het
Ero1l	G	T	14: 45,294,533	N227K	probably benign	Het
Faap24	G	T	7: 35,395,309	C58*	probably null	Het
Gm13089	G	A	4: 143,697,088	T377I	possibly damaging	Het
Hfm1	G	A	5: 106,911,575	Q194*	probably null	Het
Hs3st5	T	A	10: 36,833,323	Y285N	probably damaging	Het
Hyal6	G	A	6: 24,743,429	G375R	probably damaging	Het
Itgb5	T	C	16: 33,910,552	S93P	probably benign	Het
Kcnj6	A	T	16: 94,832,583	M205K	probably damaging	Het
Kdm6a	C	T	X: 18,247,104	Q92*	probably null	Het
Klhl38	A	G	15: 58,323,330	M1T	probably null	Het
Krtap7-1	T	C	16: 89,507,996		probably benign	Het
L1cam	T	C	X: 73,863,028	T270A	probably damaging	Het
Lmod2	A	G	6: 24,598,016	N45S	probably benign	Het
Mmp2	A	G	8: 92,839,342	I424V	probably benign	Het
Myh8	A	G	11: 67,303,913	Q1650R	possibly damaging	Het
Naalad2	T	A	9: 18,364,187	E313V	possibly damaging	Het
Nipsnap3a	A	G	4: 52,994,134	T74A	probably benign	Het
Npr2	G	T	4: 43,640,652	M368I	probably benign	Het
Nupl1	T	C	14: 60,228,775	T445A	probably benign	Het
Olfr294	A	G	7: 86,615,677	Y323H	possibly damaging	Het
Olfr582	A	G	7: 103,042,130	D212G	probably damaging	Het
Pkp3	A	G	7: 141,082,693	T73A	probably benign	Het
Pole	A	G	5: 110,301,998		probably benign	Het
Ppp2r3a	C	T	9: 101,211,192	G644D	probably benign	Het
Ptprb	T	C	10: 116,339,582	Y1161H	probably benign	Het
Ptprs	T	A	17: 56,437,943	K264N	probably damaging	Het
Rasal2	T	C	1: 157,192,741		probably benign	Het
Serpina6	A	T	12: 103,646,913	I376N	probably damaging	Het
Setx	T	G	2: 29,161,799	I2062M	probably benign	Het
Slc9c1	A	G	16: 45,543,168	D99G	probably benign	Het
Taok1	A	G	11: 77,560,328	Y309H	probably damaging	Het
Trappc10	T	C	10: 78,188,761	D1178G	probably damaging	Het
Trav5-1	G	A	14: 52,622,845	E36K	probably damaging	Het
Vmn1r237	T	C	17: 21,314,837	V274A	probably benign	Het
Washc5	C	A	15: 59,363,350		probably benign	Het
Zfp369	T	G	13: 65,296,153	L370R	possibly damaging	Het
Zfp750	T	C	11: 121,513,347	Y234C	probably damaging	Het

Other mutations in Vmn1r29

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02504:Vmn1r29	APN	6	58307670	missense	probably benign	0.03
R0457:Vmn1r29	UTSW	6	58308087	missense	probably benign	0.35
R0594:Vmn1r29	UTSW	6	58307772	missense	probably benign	0.35
R0735:Vmn1r29	UTSW	6	58307732	missense	probably damaging	0.96
R1422:Vmn1r29	UTSW	6	58307886	missense	probably damaging	1.00
R1476:Vmn1r29	UTSW	6	58307678	missense	probably benign	0.23
R1679:Vmn1r29	UTSW	6	58308018	missense	probably damaging	1.00
R1831:Vmn1r29	UTSW	6	58307707	nonsense	probably null
R1925:Vmn1r29	UTSW	6	58308102	missense	possibly damaging	0.79
R1933:Vmn1r29	UTSW	6	58307420	missense	probably benign	0.03
R4582:Vmn1r29	UTSW	6	58308032	missense	probably damaging	0.98
R4677:Vmn1r29	UTSW	6	58307300	missense	probably benign	0.02
R4706:Vmn1r29	UTSW	6	58308151	missense	probably benign	0.00
R5023:Vmn1r29	UTSW	6	58308067	nonsense	probably null
R5542:Vmn1r29	UTSW	6	58308123	missense	probably benign	0.14
R5649:Vmn1r29	UTSW	6	58307691	missense	probably benign	0.13
R5656:Vmn1r29	UTSW	6	58308167	missense	possibly damaging	0.94
R5906:Vmn1r29	UTSW	6	58307751	missense	probably benign	0.19
R6078:Vmn1r29	UTSW	6	58308095	missense	probably benign	0.01
R6349:Vmn1r29	UTSW	6	58307427	missense	probably damaging	1.00
R7946:Vmn1r29	UTSW	6	58307849	missense	probably benign	0.18
R8554:Vmn1r29	UTSW	6	58308206	makesense	probably null
R8944:Vmn1r29	UTSW	6	58307289	start gained	probably benign
R8955:Vmn1r29	UTSW	6	58307299	start codon destroyed	probably null	1.00
R9268:Vmn1r29	UTSW	6	58307592	missense	probably damaging	1.00
RF020:Vmn1r29	UTSW	6	58307543	missense	probably benign	0.01
U15987:Vmn1r29	UTSW	6	58308095	missense	probably benign	0.01

Posted On

2016-08-02