Incidental Mutation 'IGL03351:Vmn1r237'
ID 419717
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r237
Ensembl Gene ENSMUSG00000058030
Gene Name vomeronasal 1 receptor 237
Synonyms V1rf3
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.053) question?
Stock # IGL03351
Quality Score
Status
Chromosome 17
Chromosomal Location 21313963-21314912 bp(+) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to C at 21314837 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Valine to Alanine at position 274 (V274A)
Ref Sequence ENSEMBL: ENSMUSP00000076531 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000077301]
AlphaFold Q8R296
Predicted Effect probably benign
Transcript: ENSMUST00000077301
AA Change: V274A

PolyPhen 2 Score 0.056 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000076531
Gene: ENSMUSG00000058030
AA Change: V274A

DomainStartEndE-ValueType
Pfam:TAS2R 1 289 7.1e-17 PFAM
Pfam:V1R 34 289 1.9e-34 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930550L24Rik G A X: 58,918,937 V19I probably benign Het
4932414N04Rik T A 2: 68,731,083 D251E probably benign Het
4932415D10Rik T C 10: 82,283,567 probably benign Het
5730460C07Rik C T 3: 153,789,958 noncoding transcript Het
Coch G A 12: 51,603,206 R326Q probably benign Het
Cpa3 A G 3: 20,215,962 V366A probably benign Het
Csf1r C T 18: 61,117,108 Q382* probably null Het
Csta1 C A 16: 36,131,041 G4* probably null Het
Cts7 T C 13: 61,356,603 R49G probably damaging Het
Dlg5 A G 14: 24,170,454 V575A probably benign Het
Ero1l G T 14: 45,294,533 N227K probably benign Het
Faap24 G T 7: 35,395,309 C58* probably null Het
Gm13089 G A 4: 143,697,088 T377I possibly damaging Het
Hfm1 G A 5: 106,911,575 Q194* probably null Het
Hs3st5 T A 10: 36,833,323 Y285N probably damaging Het
Hyal6 G A 6: 24,743,429 G375R probably damaging Het
Itgb5 T C 16: 33,910,552 S93P probably benign Het
Kcnj6 A T 16: 94,832,583 M205K probably damaging Het
Kdm6a C T X: 18,247,104 Q92* probably null Het
Klhl38 A G 15: 58,323,330 M1T probably null Het
Krtap7-1 T C 16: 89,507,996 probably benign Het
L1cam T C X: 73,863,028 T270A probably damaging Het
Lmod2 A G 6: 24,598,016 N45S probably benign Het
Mmp2 A G 8: 92,839,342 I424V probably benign Het
Myh8 A G 11: 67,303,913 Q1650R possibly damaging Het
Naalad2 T A 9: 18,364,187 E313V possibly damaging Het
Nipsnap3a A G 4: 52,994,134 T74A probably benign Het
Npr2 G T 4: 43,640,652 M368I probably benign Het
Nupl1 T C 14: 60,228,775 T445A probably benign Het
Olfr294 A G 7: 86,615,677 Y323H possibly damaging Het
Olfr582 A G 7: 103,042,130 D212G probably damaging Het
Pkp3 A G 7: 141,082,693 T73A probably benign Het
Pole A G 5: 110,301,998 probably benign Het
Ppp2r3a C T 9: 101,211,192 G644D probably benign Het
Ptprb T C 10: 116,339,582 Y1161H probably benign Het
Ptprs T A 17: 56,437,943 K264N probably damaging Het
Rasal2 T C 1: 157,192,741 probably benign Het
Serpina6 A T 12: 103,646,913 I376N probably damaging Het
Setx T G 2: 29,161,799 I2062M probably benign Het
Slc9c1 A G 16: 45,543,168 D99G probably benign Het
Taok1 A G 11: 77,560,328 Y309H probably damaging Het
Trappc10 T C 10: 78,188,761 D1178G probably damaging Het
Trav5-1 G A 14: 52,622,845 E36K probably damaging Het
Vmn1r29 A T 6: 58,307,750 S152C probably damaging Het
Washc5 C A 15: 59,363,350 probably benign Het
Zfp369 T G 13: 65,296,153 L370R possibly damaging Het
Zfp750 T C 11: 121,513,347 Y234C probably damaging Het
Other mutations in Vmn1r237
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01300:Vmn1r237 APN 17 21314075 missense probably damaging 0.97
IGL02746:Vmn1r237 APN 17 21314218 missense possibly damaging 0.96
IGL03112:Vmn1r237 APN 17 21314106 nonsense probably null
BB009:Vmn1r237 UTSW 17 21314463 missense probably benign 0.01
BB019:Vmn1r237 UTSW 17 21314463 missense probably benign 0.01
R0478:Vmn1r237 UTSW 17 21314819 missense probably damaging 1.00
R0514:Vmn1r237 UTSW 17 21314670 missense possibly damaging 0.63
R0616:Vmn1r237 UTSW 17 21314623 missense probably damaging 1.00
R0865:Vmn1r237 UTSW 17 21314714 missense probably damaging 0.99
R1590:Vmn1r237 UTSW 17 21314039 missense probably damaging 0.99
R3022:Vmn1r237 UTSW 17 21314447 missense probably damaging 0.99
R4241:Vmn1r237 UTSW 17 21314663 missense possibly damaging 0.63
R4242:Vmn1r237 UTSW 17 21314663 missense possibly damaging 0.63
R4646:Vmn1r237 UTSW 17 21314138 missense probably benign 0.02
R5144:Vmn1r237 UTSW 17 21314426 missense possibly damaging 0.96
R5229:Vmn1r237 UTSW 17 21314371 missense probably benign 0.00
R5334:Vmn1r237 UTSW 17 21314680 missense probably benign 0.00
R5800:Vmn1r237 UTSW 17 21314807 missense probably benign 0.05
R5898:Vmn1r237 UTSW 17 21314551 missense probably damaging 0.99
R6190:Vmn1r237 UTSW 17 21314294 missense probably damaging 1.00
R6472:Vmn1r237 UTSW 17 21314354 missense probably benign 0.16
R6811:Vmn1r237 UTSW 17 21314386 missense probably benign 0.02
R7932:Vmn1r237 UTSW 17 21314463 missense probably benign 0.01
R8008:Vmn1r237 UTSW 17 21314194 missense probably damaging 1.00
R8086:Vmn1r237 UTSW 17 21314247 missense possibly damaging 0.61
X0011:Vmn1r237 UTSW 17 21314055 missense possibly damaging 0.62
Posted On 2016-08-02