Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03352:Vmn1r180'

419739

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r180

Ensembl Gene

ENSMUSG00000092473

Gene Name

vomeronasal 1 receptor 180

Synonyms

LOC232962, V1rd16

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL03352

Quality Score

Status

Chromosome

Chromosomal Location

23950632-23955691 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to A at 23952652 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Stop codon at position 80 (S80*)

Ref Sequence

ENSEMBL: ENSMUSP00000134362 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173816]

AlphaFold

B9EK86

Predicted Effect

probably null
Transcript: ENSMUST00000173816
AA Change: S80*

SMART Domains

Protein: ENSMUSP00000134362
Gene: ENSMUSG00000092473
AA Change: S80*

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	298	2.9e-15	PFAM
Pfam:7tm_1	31	286	6.7e-9	PFAM
Pfam:V1R	41	297	1.4e-17	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aoah	A	G	13: 21,000,043	S426G	probably benign	Het
Arap3	T	C	18: 37,981,302		probably benign	Het
Arhgap45	T	A	10: 80,030,751	N1029K	probably damaging	Het
Arhgef10l	A	T	4: 140,583,931	M1K	probably null	Het
Bloc1s6	T	C	2: 122,742,718	L71P	probably damaging	Het
Ccer1	G	T	10: 97,693,577	R34M	unknown	Het
Cd44	T	C	2: 102,845,414		probably benign	Het
Col17a1	T	C	19: 47,681,375		probably null	Het
Cspp1	A	G	1: 10,047,437	E38G	possibly damaging	Het
Dock10	A	T	1: 80,606,296		probably benign	Het
Dsg3	A	T	18: 20,527,632	M343L	probably benign	Het
Eif3l	G	A	15: 79,077,051		probably benign	Het
Fcrl1	T	C	3: 87,385,091	L150P	probably benign	Het
Flg2	T	G	3: 93,202,494	S610A	unknown	Het
Grin3b	C	T	10: 79,973,781	R374C	probably damaging	Het
H2-Oa	A	T	17: 34,094,403	I143F	probably damaging	Het
Itgae	C	T	11: 73,131,730	P924S	probably damaging	Het
Itpr2	T	A	6: 146,157,104	D2521V	probably damaging	Het
Laptm4a	G	A	12: 8,931,719	G143D	probably benign	Het
Lrp6	T	C	6: 134,479,763	Y846C	probably damaging	Het
Mcm10	A	T	2: 4,994,596	S749T	probably damaging	Het
Nemf	T	C	12: 69,331,905	N548D	probably damaging	Het
Nlrp4e	T	A	7: 23,320,826	L246Q	probably damaging	Het
Nsun6	A	T	2: 14,996,346	C466*	probably null	Het
Olfm2	T	C	9: 20,668,723	D252G	probably damaging	Het
Olfr112	T	A	17: 37,563,790	I174F	probably damaging	Het
Olfr1499	T	C	19: 13,814,928	I221V	probably damaging	Het
Olfr16	A	C	1: 172,957,283	M163L	probably benign	Het
Olfr91	G	A	17: 37,093,419	L152F	probably benign	Het
Pcdhb14	C	T	18: 37,449,004	R388C	possibly damaging	Het
Piwil1	C	T	5: 128,751,072	T712I	probably benign	Het
Piwil4	G	T	9: 14,725,887	T377K	probably damaging	Het
Prg3	T	C	2: 84,993,026	F182L	probably damaging	Het
Ptgds	T	C	2: 25,469,610	T22A	probably benign	Het
Retsat	T	C	6: 72,598,683	V19A	probably damaging	Het
Rpl21-ps4	A	T	14: 11,227,760		noncoding transcript	Het
Sh3glb2	A	G	2: 30,345,351	V370A	probably damaging	Het
Skint4	G	T	4: 112,165,686	W459C	possibly damaging	Het
Slco1a1	T	A	6: 141,911,885	R573S	probably benign	Het
Smgc	T	C	15: 91,860,678	S694P	probably damaging	Het
Spaca6	A	G	17: 17,838,139	Y7C	probably damaging	Het
Spn	T	C	7: 127,137,006	T110A	probably benign	Het
Ssfa2	T	A	2: 79,645,101	M468K	probably damaging	Het
Tepsin	C	T	11: 120,091,877	V456I	probably benign	Het
Tex261	C	T	6: 83,771,267	R171Q	possibly damaging	Het
Tmem184a	A	T	5: 139,813,000	F65I	probably damaging	Het
Tpm3	G	A	3: 90,087,745		probably null	Het
Tubgcp2	T	A	7: 140,001,027	H671L	probably benign	Het
Unc13b	T	G	4: 43,237,110	D3393E	possibly damaging	Het
Vcan	T	A	13: 89,705,006	M612L	probably benign	Het
Vmn1r64	C	T	7: 5,884,071	V158I	probably benign	Het
Vps13d	C	T	4: 145,167,502	V496I	possibly damaging	Het
Wee2	T	G	6: 40,452,655		probably null	Het
Zfp804b	T	C	5: 6,770,039	N972S	probably benign	Het

Other mutations in Vmn1r180

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00487:Vmn1r180	APN	7	23952523	missense	probably benign	0.36
IGL01309:Vmn1r180	APN	7	23952999	missense	probably damaging	1.00
IGL01793:Vmn1r180	APN	7	23953243	missense	probably benign	0.00
IGL02653:Vmn1r180	APN	7	23953075	missense	probably damaging	1.00
IGL03277:Vmn1r180	APN	7	23953285	missense	probably damaging	0.99
R1298:Vmn1r180	UTSW	7	23953147	missense	possibly damaging	0.84
R1701:Vmn1r180	UTSW	7	23952970	missense	possibly damaging	0.84
R1702:Vmn1r180	UTSW	7	23952969	missense	possibly damaging	0.52
R2122:Vmn1r180	UTSW	7	23953141	missense	probably damaging	1.00
R4241:Vmn1r180	UTSW	7	23952873	missense	probably damaging	1.00
R5683:Vmn1r180	UTSW	7	23953210	missense	possibly damaging	0.58
R7241:Vmn1r180	UTSW	7	23952466	missense	probably damaging	0.96
R7522:Vmn1r180	UTSW	7	23953260	missense	probably damaging	1.00
R8749:Vmn1r180	UTSW	7	23952990	missense	probably damaging	1.00
R8991:Vmn1r180	UTSW	7	23952651	missense	probably benign	0.06
R9442:Vmn1r180	UTSW	7	23952195	start gained	probably benign

Posted On

2016-08-02