Incidental Mutation 'IGL03367:Ceacam15'
ID420142
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ceacam15
Ensembl Gene ENSMUSG00000078795
Gene Namecarcinoembryonic antigen-related cell adhesion molecule 15
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.076) question?
Stock #IGL03367
Quality Score
Status
Chromosome7
Chromosomal Location16671331-16675705 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 16675587 bp
ZygosityHeterozygous
Amino Acid Change Serine to Alanine at position 8 (S8A)
Ref Sequence ENSEMBL: ENSMUSP00000104138 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000108498]
Predicted Effect possibly damaging
Transcript: ENSMUST00000108498
AA Change: S8A

PolyPhen 2 Score 0.475 (Sensitivity: 0.89; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000104138
Gene: ENSMUSG00000078795
AA Change: S8A

DomainStartEndE-ValueType
IG 39 140 1.28e-1 SMART
IGc2 156 220 2.68e-4 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
6030419C18Rik A G 9: 58,499,098 H97R probably damaging Het
Abcc5 A T 16: 20,392,811 probably benign Het
Adra1a G A 14: 66,637,989 V138I possibly damaging Het
Alpk3 A G 7: 81,094,990 I1278V probably benign Het
Asb6 A T 2: 30,824,679 I185N possibly damaging Het
Atg9a A G 1: 75,187,957 V121A probably benign Het
Cdc42bpb A G 12: 111,336,159 Y155H probably damaging Het
Cep170b T A 12: 112,737,238 D615E probably benign Het
Cntn6 G T 6: 104,804,338 G462C probably damaging Het
Col8a2 A G 4: 126,312,198 D667G probably damaging Het
Cyp2c29 A G 19: 39,329,215 K382E probably damaging Het
Dgkd T C 1: 87,940,308 probably null Het
Dkk2 C T 3: 132,178,077 T246I probably damaging Het
Dnah5 T C 15: 28,234,327 L294P possibly damaging Het
Erbb2 G T 11: 98,422,875 probably null Het
Fn1 A G 1: 71,597,553 F2147L probably benign Het
Gm11149 G A 9: 49,546,346 probably benign Het
Gm13088 C T 4: 143,655,623 V168I possibly damaging Het
Gnrhr C T 5: 86,182,331 V277I probably benign Het
H2-T10 T A 17: 36,120,393 E129V possibly damaging Het
Hmgcr T C 13: 96,665,853 T108A probably damaging Het
Hnrnph3 A T 10: 63,017,229 I196N probably damaging Het
Kcnq5 T C 1: 21,403,065 K653E probably damaging Het
Lgi2 C A 5: 52,562,160 D100Y probably damaging Het
Mettl15 T A 2: 109,131,571 H231L probably benign Het
Mthfd1l A G 10: 4,106,536 probably benign Het
Pik3cg A G 12: 32,192,121 S997P probably benign Het
Pla2g1b T C 5: 115,472,114 C105R probably damaging Het
Ppil1 A T 17: 29,252,244 probably benign Het
Rbbp8 A G 18: 11,721,719 T334A probably benign Het
Slc15a4 T C 5: 127,601,941 Y445C probably damaging Het
Sox14 A C 9: 99,875,662 I8S probably damaging Het
Spice1 A G 16: 44,356,178 T44A probably damaging Het
Sult3a1 G T 10: 33,877,346 V213L probably benign Het
Vkorc1l1 C A 5: 129,982,307 Y111* probably null Het
Wdr47 G T 3: 108,629,773 probably benign Het
Wdr90 A G 17: 25,847,791 probably benign Het
Other mutations in Ceacam15
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0144:Ceacam15 UTSW 7 16673191 missense probably benign 0.32
R0517:Ceacam15 UTSW 7 16673520 nonsense probably null
R0612:Ceacam15 UTSW 7 16673520 nonsense probably null
R0697:Ceacam15 UTSW 7 16673520 nonsense probably null
R1077:Ceacam15 UTSW 7 16672075 missense probably benign 0.03
R1257:Ceacam15 UTSW 7 16672024 missense possibly damaging 0.73
R1389:Ceacam15 UTSW 7 16672063 missense probably damaging 0.99
R4602:Ceacam15 UTSW 7 16671981 missense probably damaging 1.00
R4623:Ceacam15 UTSW 7 16673466 missense probably damaging 0.97
R4674:Ceacam15 UTSW 7 16673485 missense probably benign 0.09
R4675:Ceacam15 UTSW 7 16673485 missense probably benign 0.09
R4745:Ceacam15 UTSW 7 16673334 missense probably benign
R5296:Ceacam15 UTSW 7 16673196 missense probably benign 0.09
R5510:Ceacam15 UTSW 7 16672099 missense probably damaging 1.00
R6210:Ceacam15 UTSW 7 16673289 missense probably damaging 0.99
R7414:Ceacam15 UTSW 7 16673310 missense probably benign 0.24
X0020:Ceacam15 UTSW 7 16675606 start codon destroyed probably null 0.00
Z1176:Ceacam15 UTSW 7 16675583 missense possibly damaging 0.83
Posted On2016-08-02