Incidental Mutation 'IGL03372:Krtap19-2'
ID420322
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Krtap19-2
Ensembl Gene ENSMUSG00000057650
Gene Namekeratin associated protein 19-2
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.071) question?
Stock #IGL03372
Quality Score
Status
Chromosome16
Chromosomal Location88873627-88874269 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to G at 88873886 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000132718 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000075284] [ENSMUST00000076186] [ENSMUST00000081334]
Predicted Effect probably benign
Transcript: ENSMUST00000075284
SMART Domains Protein: ENSMUSP00000133176
Gene: ENSMUSG00000060469

DomainStartEndE-ValueType
Pfam:KRTAP 1 56 4.4e-14 PFAM
Pfam:KRTAP 49 81 1.7e-7 PFAM
Predicted Effect unknown
Transcript: ENSMUST00000076186
AA Change: C124R
SMART Domains Protein: ENSMUSP00000075543
Gene: ENSMUSG00000057650
AA Change: C124R

DomainStartEndE-ValueType
Pfam:KRTAP 1 52 3e-11 PFAM
transmembrane domain 83 105 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000081334
SMART Domains Protein: ENSMUSP00000132718
Gene: ENSMUSG00000060691

DomainStartEndE-ValueType
Pfam:KRTAP 1 57 9e-16 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 55 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrb2 C T 4: 130,017,569 A1161V probably benign Het
Alpi A G 1: 87,100,628 probably benign Het
Asxl1 A T 2: 153,400,413 N961I probably damaging Het
Bcl2l10 A G 9: 75,348,047 I49V probably benign Het
Bod1l T C 5: 41,805,235 probably benign Het
Ccl20 A G 1: 83,117,876 M54V probably benign Het
Cep72 A C 13: 74,043,518 L200V possibly damaging Het
Clic4 T C 4: 135,218,614 D164G probably damaging Het
Col5a3 G A 9: 20,775,328 P1334S unknown Het
Dab2 T C 15: 6,429,549 L293P probably damaging Het
Ddx50 A T 10: 62,643,330 S140T probably benign Het
Dnah6 A T 6: 73,075,850 M2897K probably benign Het
Dnmt3a A G 12: 3,902,666 E721G probably damaging Het
Esyt3 A T 9: 99,336,056 probably benign Het
Fat4 G T 3: 38,889,134 K725N possibly damaging Het
Fezf1 T C 6: 23,246,910 I308V probably damaging Het
Fut2 C T 7: 45,650,769 G193E possibly damaging Het
Gapdhs T C 7: 30,733,249 probably benign Het
Gm10109 A T 7: 44,221,702 probably benign Het
Gpd2 G A 2: 57,355,507 V405I probably damaging Het
Gtf2e1 T C 16: 37,535,715 probably benign Het
Iqca A G 1: 90,144,969 I63T possibly damaging Het
Kcmf1 A C 6: 72,849,563 L161R probably damaging Het
Kif19a G T 11: 114,779,218 V80L probably damaging Het
Kif21a A T 15: 90,956,376 M1179K probably benign Het
Ksr2 T A 5: 117,702,718 I575N possibly damaging Het
L3mbtl1 A T 2: 162,971,157 probably benign Het
Larp1b A T 3: 41,024,527 H6L possibly damaging Het
Map4k2 T A 19: 6,342,249 probably benign Het
Mdh1b T C 1: 63,719,995 H146R possibly damaging Het
Morc2a T C 11: 3,681,813 probably benign Het
Mvd A G 8: 122,443,374 probably benign Het
Myo7b C T 18: 31,998,601 S514N probably damaging Het
Nav1 A T 1: 135,450,903 I1610K probably damaging Het
Nbas T C 12: 13,534,472 L2095P probably damaging Het
Nrros T C 16: 32,144,770 N115S probably damaging Het
Olfr472 T C 7: 107,903,370 Y218H probably damaging Het
Otud6b A C 4: 14,812,519 I276R possibly damaging Het
P2rx6 G A 16: 17,567,492 E150K probably damaging Het
Pan2 T A 10: 128,315,127 L771Q probably benign Het
Pbrm1 T A 14: 31,085,019 N1087K probably benign Het
Pcdhb5 G T 18: 37,320,660 R31L probably benign Het
Proser3 A C 7: 30,543,568 S195A probably damaging Het
Rad50 T C 11: 53,695,294 K292E probably benign Het
Rbm27 G A 18: 42,305,716 R394H probably damaging Het
Samd9l A G 6: 3,375,314 I649T probably damaging Het
Skint3 G A 4: 112,255,906 probably benign Het
Slc4a4 T A 5: 89,156,426 L576Q probably damaging Het
Snx2 A G 18: 53,216,391 D408G probably damaging Het
Taar2 T C 10: 23,941,171 V203A probably benign Het
Tdrd6 C T 17: 43,625,568 V1530M probably damaging Het
Tsc2 A C 17: 24,619,470 L515R probably damaging Het
Unc13a A T 8: 71,655,709 M500K probably damaging Het
Vmn1r75 A G 7: 11,880,569 D76G probably benign Het
Whrn T C 4: 63,418,618 D127G probably damaging Het
Other mutations in Krtap19-2
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0520:Krtap19-2 UTSW 16 88873861 unclassified probably benign
R4779:Krtap19-2 UTSW 16 88873874 unclassified probably benign
R5038:Krtap19-2 UTSW 16 88874028 nonsense probably null
R5533:Krtap19-2 UTSW 16 88874108 unclassified probably benign
R5810:Krtap19-2 UTSW 16 88874236 unclassified probably benign
X0028:Krtap19-2 UTSW 16 88874002 unclassified probably benign
Posted On2016-08-02