Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03373:Vmn2r40'

420377

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r40

Ensembl Gene

ENSMUSG00000090864

Gene Name

vomeronasal 2, receptor 40

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL03373

Quality Score

Status

Chromosome

Chromosomal Location

8910733-8934401 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 8923092 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 423 (D423G)

Ref Sequence

ENSEMBL: ENSMUSP00000132332 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171942]

AlphaFold

F6W043

Predicted Effect

probably benign
Transcript: ENSMUST00000171942
AA Change: D423G

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000132332
Gene: ENSMUSG00000090864
AA Change: D423G

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
low complexity region	59	71	N/A	INTRINSIC
Pfam:ANF_receptor	73	468	2.2e-32	PFAM
Pfam:NCD3G	512	565	6.1e-17	PFAM
Pfam:7tm_3	547	784	1.6e-78	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam6a	A	T	12: 113,509,172 (GRCm39)	Y515F	possibly damaging	Het
Adgrv1	A	G	13: 81,711,751 (GRCm39)	V1075A	probably damaging	Het
Alox8	T	C	11: 69,077,443 (GRCm39)	T436A	probably benign	Het
Cdc7	T	A	5: 107,120,785 (GRCm39)		probably benign	Het
Cdhr1	T	A	14: 36,818,257 (GRCm39)	D65V	possibly damaging	Het
Dnase1	A	G	16: 3,857,707 (GRCm39)	E278G	probably damaging	Het
Eif3g	A	T	9: 20,805,722 (GRCm39)		probably benign	Het
Flnb	G	A	14: 7,890,867 (GRCm38)		probably null	Het
Hars2	G	T	18: 36,918,998 (GRCm39)	R86L	probably damaging	Het
Lmod1	C	T	1: 135,292,264 (GRCm39)	A373V	possibly damaging	Het
Mdga2	A	G	12: 66,763,496 (GRCm39)	I200T	probably damaging	Het
Mup1	T	G	4: 60,457,849 (GRCm39)		probably benign	Het
Nat8f5	A	C	6: 85,794,529 (GRCm39)	S144A	probably benign	Het
Ndnf	A	C	6: 65,681,272 (GRCm39)	Y517S	possibly damaging	Het
Nedd4l	G	A	18: 65,314,391 (GRCm39)		probably benign	Het
Nlrp4g	A	T	9: 124,349,853 (GRCm38)		noncoding transcript	Het
Nob1	C	T	8: 108,144,678 (GRCm39)		probably benign	Het
Nploc4	G	A	11: 120,300,455 (GRCm39)	R326*	probably null	Het
Obox3	A	T	7: 15,359,715 (GRCm39)	V318D	probably benign	Het
Or10a3m	G	A	7: 108,313,339 (GRCm39)	V248I	probably damaging	Het
Or10ag57	T	C	2: 87,218,577 (GRCm39)	F176S	probably damaging	Het
Pgm1	T	C	4: 99,818,741 (GRCm39)	I130T	probably damaging	Het
Ptprk	A	T	10: 28,442,533 (GRCm39)	D845V	probably damaging	Het
Ptx4	T	A	17: 25,339,873 (GRCm39)	S17T	probably benign	Het
Rasgrf1	T	C	9: 89,899,084 (GRCm39)		probably benign	Het
Rfx6	A	G	10: 51,596,096 (GRCm39)	T426A	probably damaging	Het
Sfpq	C	A	4: 126,920,578 (GRCm39)	R564S	possibly damaging	Het
Spint2	A	G	7: 28,957,634 (GRCm39)		probably benign	Het
Vmn1r27	A	G	6: 58,192,689 (GRCm39)	I105T	probably damaging	Het
Vmn1r78	T	C	7: 11,887,270 (GRCm39)	S294P	possibly damaging	Het

Other mutations in Vmn2r40

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01018:Vmn2r40	APN	7	8,911,175 (GRCm39)	missense	probably damaging	0.97
IGL01678:Vmn2r40	APN	7	8,923,105 (GRCm39)	missense	probably damaging	0.99
R4996:Vmn2r40	UTSW	7	8,911,166 (GRCm39)	missense	probably damaging	1.00
R5522:Vmn2r40	UTSW	7	8,911,203 (GRCm39)	missense	probably benign	0.30
R6767:Vmn2r40	UTSW	7	8,923,139 (GRCm39)	missense	unknown
R6785:Vmn2r40	UTSW	7	8,911,203 (GRCm39)	missense	probably benign	0.30
R7631:Vmn2r40	UTSW	7	8,911,119 (GRCm39)	missense
R7714:Vmn2r40	UTSW	7	8,911,116 (GRCm39)	missense
R8053:Vmn2r40	UTSW	7	8,911,245 (GRCm39)	missense
R8298:Vmn2r40	UTSW	7	8,911,148 (GRCm39)	missense
R8544:Vmn2r40	UTSW	7	8,911,191 (GRCm39)	missense
R8894:Vmn2r40	UTSW	7	8,923,197 (GRCm39)	missense
R9093:Vmn2r40	UTSW	7	8,911,172 (GRCm39)	missense

Posted On

2016-08-02