Incidental Mutation 'IGL03375:Krtap6-2'
ID420465
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Krtap6-2
Ensembl Gene ENSMUSG00000062433
Gene Namekeratin associated protein 6-2
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.080) question?
Stock #IGL03375
Quality Score
Status
Chromosome16
Chromosomal Location89419326-89420111 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 89419756 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Histidine at position 108 (Y108H)
Ref Sequence ENSEMBL: ENSMUSP00000139661 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000082065]
Predicted Effect unknown
Transcript: ENSMUST00000082065
AA Change: Y108H
SMART Domains Protein: ENSMUSP00000139661
Gene: ENSMUSG00000062433
AA Change: Y108H

DomainStartEndE-ValueType
low complexity region 2 152 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arhgap31 A G 16: 38,602,828 S959P probably damaging Het
Arrb2 G A 11: 70,436,179 G24D probably damaging Het
Catsper4 A G 4: 134,218,208 I180T probably damaging Het
Chst15 G A 7: 132,270,457 Q32* probably null Het
Cntnap5c A T 17: 58,162,205 Y594F possibly damaging Het
Cse1l T A 2: 166,943,057 probably benign Het
Dab1 A T 4: 104,681,601 I201F possibly damaging Het
Eif2ak4 T C 2: 118,422,318 V457A probably benign Het
Fkbp1b T C 12: 4,838,220 probably benign Het
Fryl C A 5: 73,088,449 V1122F possibly damaging Het
Gas2l2 A G 11: 83,426,210 probably benign Het
Gm960 T C 19: 4,698,178 E164G probably benign Het
Gstt2 A T 10: 75,832,821 probably null Het
Hcst T G 7: 30,418,611 probably benign Het
Hectd4 A G 5: 121,328,382 E2420G possibly damaging Het
Hist2h4 T C 3: 96,263,142 T55A possibly damaging Het
Ifi206 A T 1: 173,480,778 S551T probably benign Het
Itgb3bp A G 4: 99,769,487 probably benign Het
Krtap6-5 T G 16: 89,047,852 probably benign Het
Muc5b A G 7: 141,861,962 T2882A possibly damaging Het
Nup214 C T 2: 32,010,221 T854M probably damaging Het
Olfml2b A G 1: 170,649,832 K179E probably benign Het
Olfr1281 A T 2: 111,328,884 H155L probably damaging Het
Olfr149 A G 9: 39,702,575 S65P probably damaging Het
Per2 A T 1: 91,424,228 I852K possibly damaging Het
Pkhd1 A T 1: 20,117,023 I3687N probably damaging Het
Slc7a2 A T 8: 40,916,373 S622C probably damaging Het
Smarcc2 G A 10: 128,482,912 V719I probably damaging Het
Syne2 T C 12: 75,925,435 I1033T possibly damaging Het
Tmod1 T C 4: 46,096,999 I264T probably damaging Het
Tmtc3 G A 10: 100,447,719 A658V possibly damaging Het
Tpm3 A G 3: 90,073,772 E56G possibly damaging Het
Tra2b T C 16: 22,247,243 probably benign Het
Trmu T A 15: 85,894,937 Y262N possibly damaging Het
Uox C T 3: 146,625,835 T213I probably damaging Het
Vps13d A G 4: 145,091,947 W2R probably damaging Het
Other mutations in Krtap6-2
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1566:Krtap6-2 UTSW 16 89419738 missense unknown
R4896:Krtap6-2 UTSW 16 89419918 missense unknown
R5857:Krtap6-2 UTSW 16 89419642 missense unknown
R6390:Krtap6-2 UTSW 16 89419946 nonsense probably null
R6958:Krtap6-2 UTSW 16 89419810 missense unknown
R7432:Krtap6-2 UTSW 16 89419873 missense unknown
R7454:Krtap6-2 UTSW 16 89419912 missense unknown
R7780:Krtap6-2 UTSW 16 89419622 nonsense probably null
Posted On2016-08-02