Incidental Mutation 'IGL03380:Vmn1r191'
ID420635
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r191
Ensembl Gene ENSMUSG00000095916
Gene Namevomeronasal 1 receptor 191
SynonymsV1rh15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.153) question?
Stock #IGL03380
Quality Score
Status
Chromosome13
Chromosomal Location22178686-22179582 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 22178885 bp
ZygosityHeterozygous
Amino Acid Change Serine to Asparagine at position 233 (S233N)
Ref Sequence ENSEMBL: ENSMUSP00000072206 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072369]
Predicted Effect probably damaging
Transcript: ENSMUST00000072369
AA Change: S233N

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000072206
Gene: ENSMUSG00000095916
AA Change: S233N

DomainStartEndE-ValueType
transmembrane domain 12 34 N/A INTRINSIC
Pfam:V1R 35 291 4.4e-33 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000120067
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca13 A G 11: 9,298,574 N2774D probably benign Het
Aldh1a2 T G 9: 71,255,117 Y149* probably null Het
Ank2 C A 3: 126,955,870 E503D probably damaging Het
Arhgap23 A G 11: 97,452,518 D542G probably damaging Het
Atp8a1 T C 5: 67,732,186 E582G probably benign Het
C4b A T 17: 34,740,286 V438D probably benign Het
Caps2 A G 10: 112,200,696 E345G probably benign Het
Cdk19 C T 10: 40,476,912 P308L probably benign Het
Drc3 A G 11: 60,377,905 E307G probably benign Het
Dst G A 1: 34,257,800 A1041T probably damaging Het
Elp2 T C 18: 24,622,480 V428A probably benign Het
Eml5 G T 12: 98,874,647 probably benign Het
Fam120b G A 17: 15,403,134 probably benign Het
Fpr-rs6 G A 17: 20,182,983 L39F possibly damaging Het
Fsd1 T C 17: 55,995,456 I300T probably benign Het
Hsd17b6 T C 10: 127,994,338 probably null Het
Hspa1a T C 17: 34,970,277 K550R probably benign Het
Krba1 A G 6: 48,403,453 H37R possibly damaging Het
Lama2 T C 10: 27,050,265 D2117G probably damaging Het
Map4k2 T C 19: 6,344,590 F332S possibly damaging Het
Mindy1 T C 3: 95,291,018 probably benign Het
Nhsl1 T G 10: 18,523,879 Y284* probably null Het
Olfr1463 T A 19: 13,235,001 F250L probably benign Het
Pkhd1 T A 1: 20,200,670 T3220S probably damaging Het
Pramel7 A T 2: 87,491,372 D106E probably benign Het
Psme3 T C 11: 101,320,026 probably null Het
Rsph1 T C 17: 31,277,236 E7G unknown Het
Slc13a2 T C 11: 78,399,082 T469A probably benign Het
Slc30a9 C T 5: 67,315,711 T46I probably benign Het
Slc37a4 T G 9: 44,400,023 S204A probably benign Het
Slc8b1 T C 5: 120,519,735 F88L probably damaging Het
Smpd3 C T 8: 106,259,659 V504I probably benign Het
Tbx4 A G 11: 85,914,639 N418S probably benign Het
Tmem132c A G 5: 127,536,442 T470A probably benign Het
Tmem207 A T 16: 26,526,657 C20S probably damaging Het
Usp43 G A 11: 67,875,316 A761V possibly damaging Het
Vmn2r58 T A 7: 41,864,450 E256D probably benign Het
Zc3hav1 T C 6: 38,336,558 Y184C probably damaging Het
Other mutations in Vmn1r191
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00233:Vmn1r191 APN 13 22178720 missense probably damaging 1.00
IGL01645:Vmn1r191 APN 13 22179444 missense probably benign 0.03
IGL02224:Vmn1r191 APN 13 22178898 missense probably damaging 1.00
IGL02321:Vmn1r191 APN 13 22178898 nonsense probably null
IGL02516:Vmn1r191 APN 13 22179540 missense probably benign 0.38
IGL02602:Vmn1r191 APN 13 22179465 missense probably damaging 1.00
IGL02630:Vmn1r191 APN 13 22179261 missense possibly damaging 0.95
IGL03077:Vmn1r191 APN 13 22179146 missense probably benign 0.07
R0571:Vmn1r191 UTSW 13 22179047 missense probably damaging 0.96
R0981:Vmn1r191 UTSW 13 22179219 missense probably benign 0.00
R1672:Vmn1r191 UTSW 13 22179092 missense probably benign 0.01
R1955:Vmn1r191 UTSW 13 22178815 missense possibly damaging 0.79
R1969:Vmn1r191 UTSW 13 22178782 missense possibly damaging 0.71
R5059:Vmn1r191 UTSW 13 22178993 missense probably damaging 1.00
R6484:Vmn1r191 UTSW 13 22178748 missense probably benign 0.00
R6736:Vmn1r191 UTSW 13 22179550 missense probably benign 0.14
R7063:Vmn1r191 UTSW 13 22178694 missense probably benign 0.08
R7475:Vmn1r191 UTSW 13 22178772 missense probably benign 0.00
Posted On2016-08-02