Incidental Mutation 'IGL03390:Cdnf'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cdnf
Ensembl Gene ENSMUSG00000039496
Gene Namecerebral dopamine neurotrophic factor
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.039) question?
Stock #IGL03390
Quality Score
Chromosomal Location3513030-3526376 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 3523826 bp
Amino Acid Change Leucine to Stop codon at position 134 (L134*)
Ref Sequence ENSEMBL: ENSMUSP00000046297 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000036350]
Predicted Effect probably null
Transcript: ENSMUST00000036350
AA Change: L134*
SMART Domains Protein: ENSMUSP00000046297
Gene: ENSMUSG00000039496
AA Change: L134*

signal peptide 1 24 N/A INTRINSIC
Pfam:Armet 36 181 2.6e-70 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000132566
Predicted Effect noncoding transcript
Transcript: ENSMUST00000140610
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2810004N23Rik A G 8: 124,839,825 probably benign Het
Ccdc18 A G 5: 108,212,131 Y1127C probably damaging Het
Col11a1 A G 3: 114,090,253 D257G unknown Het
Cthrc1 T A 15: 39,077,134 I44N probably benign Het
Dlec1 T C 9: 119,123,220 Y545H probably benign Het
Drosha T G 15: 12,884,983 probably null Het
Ebf2 A G 14: 67,424,109 N562S probably benign Het
Fem1b G A 9: 62,796,964 A338V probably benign Het
Gga3 A T 11: 115,586,994 probably null Het
Gm7247 A T 14: 51,523,457 H161L probably benign Het
Gm7367 A G 7: 60,155,769 noncoding transcript Het
Inpp5a T G 7: 139,525,748 V213G probably benign Het
Kcns3 T C 12: 11,091,232 T489A probably benign Het
Kifc3 G A 8: 95,108,613 A211V probably damaging Het
Krt71 T C 15: 101,734,552 D507G possibly damaging Het
Lama5 T C 2: 180,207,218 Y224C probably damaging Het
Lrrc37a A G 11: 103,496,031 L2421P unknown Het
Mtch2 C T 2: 90,859,550 T205I probably benign Het
Olfr108 T C 17: 37,446,364 V281A probably benign Het
Prkdc T A 16: 15,670,626 C537* probably null Het
Prl2a1 T C 13: 27,801,716 V5A probably benign Het
Prob1 T C 18: 35,654,139 Y354C probably benign Het
Rimklb C T 6: 122,456,321 S347N possibly damaging Het
Rnase2a T C 14: 51,255,488 D140G probably damaging Het
Ryr2 G A 13: 11,772,416 P1017S probably benign Het
Slc3a1 A G 17: 85,032,777 D209G probably damaging Het
Sntn T A 14: 13,682,205 probably benign Het
Tal2 G T 4: 53,785,994 L58F probably damaging Het
Trim39 T C 17: 36,260,571 K432E probably damaging Het
Trmt5 A T 12: 73,282,727 M219K probably benign Het
Vmn2r3 T A 3: 64,275,346 I311L possibly damaging Het
Wfdc17 A T 11: 83,704,785 probably benign Het
Zbtb6 T G 2: 37,429,572 I115L probably damaging Het
Zfp750 A T 11: 121,511,944 C659* probably null Het
Other mutations in Cdnf
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00773:Cdnf APN 2 3519355 missense possibly damaging 0.73
IGL02552:Cdnf APN 2 3523975 nonsense probably null
R1528:Cdnf UTSW 2 3521041 missense probably damaging 1.00
R2846:Cdnf UTSW 2 3513128 start codon destroyed probably null 0.99
R4077:Cdnf UTSW 2 3521023 missense probably damaging 1.00
Z1177:Cdnf UTSW 2 3521083 missense possibly damaging 0.50
Posted On2016-08-02