Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03390:Sntn'

421041

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sntn

Ensembl Gene

ENSMUSG00000044772

Gene Name

sentan, cilia apical structure protein

Synonyms

A430083B19Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.028) question?

Stock #

IGL03390

Quality Score

Status

Chromosome

Chromosomal Location

8786615-8798887 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to A at 13682205 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000062092 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000061045]

AlphaFold

Q8C9X1

Predicted Effect

probably benign
Transcript: ENSMUST00000061045

SMART Domains

Protein: ENSMUSP00000062092
Gene: ENSMUSG00000044772

Domain	Start	End	E-Value	Type
low complexity region	19	32	N/A	INTRINSIC
SCOP:d1psra_	53	133	2e-15	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810004N23Rik	A	G	8: 125,566,564 (GRCm39)		probably benign	Het
Ccdc18	A	G	5: 108,359,997 (GRCm39)	Y1127C	probably damaging	Het
Cdnf	T	A	2: 3,524,863 (GRCm39)	L134*	probably null	Het
Col11a1	A	G	3: 113,883,902 (GRCm39)	D257G	unknown	Het
Cthrc1	T	A	15: 38,940,529 (GRCm39)	I44N	probably benign	Het
Dlec1	T	C	9: 118,952,288 (GRCm39)	Y545H	probably benign	Het
Drosha	T	G	15: 12,885,069 (GRCm39)		probably null	Het
Ebf2	A	G	14: 67,661,558 (GRCm39)	N562S	probably benign	Het
Fem1b	G	A	9: 62,704,246 (GRCm39)	A338V	probably benign	Het
Gga3	A	T	11: 115,477,820 (GRCm39)		probably null	Het
Gm7247	A	T	14: 51,760,914 (GRCm39)	H161L	probably benign	Het
Gm7367	A	G	7: 59,805,517 (GRCm39)		noncoding transcript	Het
Inpp5a	T	G	7: 139,105,664 (GRCm39)	V213G	probably benign	Het
Kcns3	T	C	12: 11,141,233 (GRCm39)	T489A	probably benign	Het
Kifc3	G	A	8: 95,835,241 (GRCm39)	A211V	probably damaging	Het
Krt71	T	C	15: 101,642,987 (GRCm39)	D507G	possibly damaging	Het
Lama5	T	C	2: 179,849,011 (GRCm39)	Y224C	probably damaging	Het
Lrrc37a	A	G	11: 103,386,857 (GRCm39)	L2421P	unknown	Het
Mtch2	C	T	2: 90,689,894 (GRCm39)	T205I	probably benign	Het
Or1o11	T	C	17: 37,757,255 (GRCm39)	V281A	probably benign	Het
Prkdc	T	A	16: 15,488,490 (GRCm39)	C537*	probably null	Het
Prl2a1	T	C	13: 27,985,699 (GRCm39)	V5A	probably benign	Het
Prob1	T	C	18: 35,787,192 (GRCm39)	Y354C	probably benign	Het
Rimklb	C	T	6: 122,433,280 (GRCm39)	S347N	possibly damaging	Het
Rnase2a	T	C	14: 51,492,945 (GRCm39)	D140G	probably damaging	Het
Ryr2	G	A	13: 11,787,302 (GRCm39)	P1017S	probably benign	Het
Slc3a1	A	G	17: 85,340,205 (GRCm39)	D209G	probably damaging	Het
Tal2	G	T	4: 53,785,994 (GRCm39)	L58F	probably damaging	Het
Trim39	T	C	17: 36,571,463 (GRCm39)	K432E	probably damaging	Het
Trmt5	A	T	12: 73,329,501 (GRCm39)	M219K	probably benign	Het
Vmn2r3	T	A	3: 64,182,767 (GRCm39)	I311L	possibly damaging	Het
Wfdc17	A	T	11: 83,595,611 (GRCm39)		probably benign	Het
Zbtb6	T	G	2: 37,319,584 (GRCm39)	I115L	probably damaging	Het
Zfp750	A	T	11: 121,402,770 (GRCm39)	C659*	probably null	Het

Other mutations in Sntn

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00331:Sntn	APN	14	13,679,086 (GRCm38)	nonsense	probably null
IGL03338:Sntn	APN	14	13,678,991 (GRCm38)	missense	probably damaging	1.00
R3902:Sntn	UTSW	14	13,679,084 (GRCm38)	missense	probably damaging	1.00
R4865:Sntn	UTSW	14	13,679,103 (GRCm38)	missense	probably benign
R5494:Sntn	UTSW	14	13,682,214 (GRCm38)	missense	probably benign
R7000:Sntn	UTSW	14	13,679,108 (GRCm38)	missense	probably damaging	0.98
R8185:Sntn	UTSW	14	13,679,014 (GRCm38)	missense	probably benign	0.01
R9443:Sntn	UTSW	14	13,682,364 (GRCm38)	missense

Posted On

2016-08-02