Incidental Mutation 'IGL03402:Zfp810'
ID 421458
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp810
Ensembl Gene ENSMUSG00000066829
Gene Name zinc finger protein 810
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.079) question?
Stock # IGL03402
Quality Score
Status
Chromosome 9
Chromosomal Location 22276748-22307648 bp(-) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) A to C at 22279145 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000150816 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000086278] [ENSMUST00000215202]
AlphaFold Q99K45
Predicted Effect probably damaging
Transcript: ENSMUST00000086278
AA Change: C156G

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000083459
Gene: ENSMUSG00000066829
AA Change: C156G

DomainStartEndE-ValueType
KRAB 4 64 1.09e-33 SMART
ZnF_C2H2 126 148 2.44e2 SMART
ZnF_C2H2 182 204 3.07e-1 SMART
ZnF_C2H2 210 232 8.47e-4 SMART
ZnF_C2H2 238 260 6.78e-3 SMART
ZnF_C2H2 266 288 6.13e-1 SMART
ZnF_C2H2 294 316 5.06e-2 SMART
ZnF_C2H2 322 344 4.79e-3 SMART
ZnF_C2H2 350 372 2.99e-4 SMART
ZnF_C2H2 378 400 1.33e-1 SMART
ZnF_C2H2 406 428 2.75e-3 SMART
ZnF_C2H2 434 456 1.58e-3 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214499
Predicted Effect probably null
Transcript: ENSMUST00000215202
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700019A02Rik T C 1: 53,177,813 H81R probably benign Het
Alg10b A T 15: 90,228,329 K459* probably null Het
C8g A T 2: 25,498,812 *203K probably null Het
Cacna1b T C 2: 24,762,809 E80G probably damaging Het
Cdh12 T A 15: 21,583,740 N555K probably benign Het
Cenpf T A 1: 189,655,076 N1669I probably damaging Het
Cpsf1 A G 15: 76,596,003 probably null Het
Ear1 A G 14: 43,819,118 S98P probably benign Het
Elfn2 A T 15: 78,673,470 D292E possibly damaging Het
Fbxw24 T C 9: 109,601,248 S443G probably damaging Het
Fnip2 T C 3: 79,481,276 E716G possibly damaging Het
Gabra1 G T 11: 42,133,518 N443K probably damaging Het
Grik5 A T 7: 25,015,469 V700E probably damaging Het
Ifi27 T A 12: 103,439,513 N162K probably damaging Het
Myom2 A T 8: 15,065,731 T49S probably benign Het
Obsl1 T C 1: 75,486,799 M1750V probably benign Het
Olfr1385 A T 11: 49,495,046 H171L probably benign Het
Olfr168 A T 16: 19,530,917 M1K probably null Het
Olfr980 A T 9: 40,006,506 W148R probably benign Het
Ppp2r5e A G 12: 75,464,893 V352A probably damaging Het
Prkca T A 11: 108,340,663 Q63L probably benign Het
Scgb2b7 A T 7: 31,705,081 C65S probably damaging Het
Slfn14 T C 11: 83,276,313 K792R probably benign Het
Slfn3 C T 11: 83,213,431 T376M probably damaging Het
Snx19 A T 9: 30,440,134 I135F possibly damaging Het
Stab2 A T 10: 86,969,301 V271E probably benign Het
Trpv1 T G 11: 73,239,637 F190V possibly damaging Het
Urb2 T C 8: 124,029,849 V765A possibly damaging Het
Vmn2r61 A G 7: 42,260,255 H68R probably benign Het
Vps8 T C 16: 21,448,398 I177T possibly damaging Het
Other mutations in Zfp810
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00484:Zfp810 APN 9 22278309 nonsense probably null
IGL03079:Zfp810 APN 9 22284127 missense probably damaging 1.00
H8562:Zfp810 UTSW 9 22279091 missense probably benign 0.42
R1116:Zfp810 UTSW 9 22279085 missense probably benign 0.11
R1160:Zfp810 UTSW 9 22278532 missense possibly damaging 0.64
R1171:Zfp810 UTSW 9 22278826 missense possibly damaging 0.95
R1393:Zfp810 UTSW 9 22280514 missense probably benign
R1608:Zfp810 UTSW 9 22278920 missense probably benign 0.00
R1644:Zfp810 UTSW 9 22279028 missense possibly damaging 0.67
R1766:Zfp810 UTSW 9 22278532 missense possibly damaging 0.64
R2568:Zfp810 UTSW 9 22279238 missense probably benign 0.01
R3684:Zfp810 UTSW 9 22278235 missense probably benign 0.01
R4002:Zfp810 UTSW 9 22278892 missense probably damaging 1.00
R4134:Zfp810 UTSW 9 22279073 missense probably damaging 0.97
R4135:Zfp810 UTSW 9 22279073 missense probably damaging 0.97
R4334:Zfp810 UTSW 9 22278784 missense probably benign 0.00
R4545:Zfp810 UTSW 9 22278745 missense probably damaging 0.96
R5399:Zfp810 UTSW 9 22278829 missense possibly damaging 0.91
R5622:Zfp810 UTSW 9 22279096 missense probably benign 0.00
R5643:Zfp810 UTSW 9 22283171 missense probably benign 0.26
R7375:Zfp810 UTSW 9 22290537 critical splice donor site probably null
R7441:Zfp810 UTSW 9 22279272 nonsense probably null
R7809:Zfp810 UTSW 9 22278982 missense possibly damaging 0.51
R8422:Zfp810 UTSW 9 22283222 nonsense probably null
R8526:Zfp810 UTSW 9 22278290 missense probably damaging 1.00
R8719:Zfp810 UTSW 9 22279275 missense probably benign 0.00
R9177:Zfp810 UTSW 9 22278640 missense probably damaging 1.00
Posted On 2016-08-02