Incidental Mutation 'IGL03406:Slco6b1'
ID 421605
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slco6b1
Ensembl Gene ENSMUSG00000045463
Gene Name solute carrier organic anion transporter family, member 6b1
Synonyms 1700022M03Rik
Accession Numbers
Essential gene? Probably non essential (E-score: 0.070) question?
Stock # IGL03406
Quality Score
Status
Chromosome 1
Chromosomal Location 96849643-96924962 bp(-) (GRCm39)
Type of Mutation exon
DNA Base Change (assembly) T to C at 96875310 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000167383
Predicted Effect noncoding transcript
Transcript: ENSMUST00000178359
SMART Domains Protein: ENSMUSP00000136663
Gene: ENSMUSG00000045463

DomainStartEndE-ValueType
Pfam:MFS_1 103 481 1.6e-12 PFAM
Pfam:OATP 108 668 9.7e-128 PFAM
Pfam:Kazal_2 511 552 5.1e-8 PFAM
transmembrane domain 670 692 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A530016L24Rik T A 12: 112,463,317 (GRCm39) probably null Het
Adcy7 C T 8: 89,044,947 (GRCm39) R228* probably null Het
Cdcp1 T C 9: 123,014,378 (GRCm39) H132R probably benign Het
Cfap107 A G 4: 144,150,414 (GRCm39) Y56H probably damaging Het
Cyp4a32 T C 4: 115,459,500 (GRCm39) I78T probably benign Het
Fap A T 2: 62,372,466 (GRCm39) probably benign Het
Gad1-ps C T 10: 99,280,641 (GRCm39) noncoding transcript Het
Gli3 T C 13: 15,823,166 (GRCm39) I296T probably damaging Het
H2-Q2 T C 17: 35,561,801 (GRCm39) V97A probably benign Het
Hr T A 14: 70,800,860 (GRCm39) probably null Het
Itgax C T 7: 127,748,370 (GRCm39) T1133I possibly damaging Het
L3mbtl2 G A 15: 81,566,194 (GRCm39) R339H probably damaging Het
Mast4 T C 13: 102,873,615 (GRCm39) K1726E possibly damaging Het
Nlrc5 T C 8: 95,203,483 (GRCm39) Y528H probably benign Het
Nmnat3 G A 9: 98,281,530 (GRCm39) G44D probably damaging Het
Nol8 A T 13: 49,815,044 (GRCm39) D366V probably damaging Het
Or13a25 C A 7: 140,247,424 (GRCm39) L68M probably damaging Het
Pde4d A T 13: 110,091,125 (GRCm39) probably benign Het
Ptpn22 C A 3: 103,819,332 (GRCm39) N795K probably benign Het
Rabgap1l A T 1: 160,549,739 (GRCm39) V289D probably damaging Het
Slc50a1 T C 3: 89,177,408 (GRCm39) D40G possibly damaging Het
Smarcad1 T A 6: 65,069,510 (GRCm39) F530Y probably damaging Het
Spag6 A G 2: 18,747,684 (GRCm39) probably benign Het
Supt16 A T 14: 52,415,598 (GRCm39) I379N possibly damaging Het
Tmem154 A G 3: 84,591,567 (GRCm39) N39S probably benign Het
Ubash3b T A 9: 40,948,775 (GRCm39) Y180F probably damaging Het
Usp48 T A 4: 137,366,606 (GRCm39) D921E possibly damaging Het
Zdhhc20 T C 14: 58,076,556 (GRCm39) T366A probably benign Het
Zfp456 A T 13: 67,514,450 (GRCm39) C419S probably damaging Het
Zfp69 T C 4: 120,788,281 (GRCm39) T345A probably benign Het
Other mutations in Slco6b1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00434:Slco6b1 APN 1 96,916,375 (GRCm39) exon noncoding transcript
IGL02110:Slco6b1 APN 1 96,915,607 (GRCm39) exon noncoding transcript
IGL02416:Slco6b1 APN 1 96,852,058 (GRCm39) exon noncoding transcript
R0147:Slco6b1 UTSW 1 96,915,562 (GRCm39) exon noncoding transcript
R0277:Slco6b1 UTSW 1 96,916,398 (GRCm39) exon noncoding transcript
R0513:Slco6b1 UTSW 1 96,924,909 (GRCm39) unclassified noncoding transcript
R1401:Slco6b1 UTSW 1 96,857,610 (GRCm39) splice site noncoding transcript
R1823:Slco6b1 UTSW 1 96,888,901 (GRCm39) exon noncoding transcript
R1888:Slco6b1 UTSW 1 96,849,786 (GRCm39) splice site noncoding transcript
R4125:Slco6b1 UTSW 1 96,915,622 (GRCm39) exon noncoding transcript
R4281:Slco6b1 UTSW 1 96,925,115 (GRCm39) unclassified noncoding transcript
R4282:Slco6b1 UTSW 1 96,925,115 (GRCm39) unclassified noncoding transcript
R4576:Slco6b1 UTSW 1 96,916,422 (GRCm39) exon noncoding transcript
R4850:Slco6b1 UTSW 1 96,839,558 (GRCm39) unclassified noncoding transcript
R5222:Slco6b1 UTSW 1 96,925,216 (GRCm39) unclassified noncoding transcript
R5389:Slco6b1 UTSW 1 96,916,309 (GRCm39) exon noncoding transcript
R5801:Slco6b1 UTSW 1 96,875,356 (GRCm39) exon noncoding transcript
Posted On 2016-08-02