Incidental Mutation 'IGL03410:Olfr32'
ID421777
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr32
Ensembl Gene ENSMUSG00000075066
Gene Nameolfactory receptor 32
SynonymsMOR227-9_p, GA_x6K02T2Q125-51573576-51572650, MOR227-7P, MTPCR05
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.076) question?
Stock #IGL03410
Quality Score
Status
Chromosome2
Chromosomal Location90136273-90142296 bp(-) (GRCm38)
Type of Mutationstart gained
DNA Base Change (assembly) G to A at 90139145 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000149175 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000099755] [ENSMUST00000213293] [ENSMUST00000214973] [ENSMUST00000215153] [ENSMUST00000215659] [ENSMUST00000215765]
Predicted Effect probably benign
Transcript: ENSMUST00000099755
SMART Domains Protein: ENSMUSP00000097344
Gene: ENSMUSG00000075066

DomainStartEndE-ValueType
Pfam:7tm_4 28 302 1.7e-52 PFAM
Pfam:7tm_1 38 284 6.8e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000213293
Predicted Effect probably benign
Transcript: ENSMUST00000214973
Predicted Effect probably benign
Transcript: ENSMUST00000215153
Predicted Effect probably benign
Transcript: ENSMUST00000215659
Predicted Effect probably benign
Transcript: ENSMUST00000215765
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 52 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700010I14Rik T A 17: 9,001,896 V409E probably damaging Het
1700086D15Rik A G 11: 65,152,567 probably benign Het
Apba1 A G 19: 23,937,581 N715S possibly damaging Het
Arfgef3 G T 10: 18,600,490 A1527D probably damaging Het
Cmtm2a G T 8: 104,283,869 P133T probably damaging Het
Cyp2d9 T C 15: 82,456,699 V483A probably benign Het
Dclre1b T A 3: 103,808,140 D14V probably damaging Het
Dock5 T C 14: 67,846,086 I125V probably benign Het
Dok3 G T 13: 55,524,231 Y211* probably null Het
Fat4 T C 3: 38,891,176 V1406A probably damaging Het
Fbn2 A G 18: 58,050,243 F1790S possibly damaging Het
Gm13083 C A 4: 143,615,281 H93Q probably benign Het
Gm4787 A T 12: 81,379,174 M70K probably damaging Het
Gulp1 A T 1: 44,708,617 D10V probably damaging Het
Hagh T C 17: 24,860,942 probably benign Het
Htt A G 5: 34,799,445 E206G probably damaging Het
Hyou1 A G 9: 44,388,058 E682G probably benign Het
Igkv4-59 G T 6: 69,438,466 A35E probably damaging Het
Krt78 A G 15: 101,953,986 V80A probably damaging Het
Lars2 G A 9: 123,418,776 A333T possibly damaging Het
Lrrc4 G A 6: 28,830,516 R367W probably damaging Het
Med1 A T 11: 98,189,183 M44K possibly damaging Het
Mep1a T A 17: 43,478,095 probably null Het
Mmrn1 A G 6: 60,975,835 I367V probably benign Het
Myo18a T C 11: 77,848,004 L1677P probably damaging Het
Neb T C 2: 52,319,705 T246A probably benign Het
Nkiras1 A G 14: 18,280,073 R155G probably benign Het
Nrip1 T C 16: 76,292,491 N726S probably benign Het
Nyap2 A G 1: 81,241,441 T393A possibly damaging Het
Olfr1029 T A 2: 85,975,420 M59K probably damaging Het
Olfr1272 A G 2: 90,282,213 Y121H probably damaging Het
Oprm1 A T 10: 6,830,051 I238F probably damaging Het
Pcnx2 T A 8: 125,887,040 E557D probably damaging Het
Pole A G 5: 110,324,559 I1563V probably benign Het
Prdx3 T G 19: 60,871,410 probably benign Het
Rgsl1 C T 1: 153,793,755 R295K probably null Het
Rhbdl2 T A 4: 123,829,670 L289* probably null Het
Rnps1 A G 17: 24,421,861 probably benign Het
Rpgrip1 A G 14: 52,158,366 probably benign Het
Ryr2 A T 13: 11,588,147 Y4518N probably damaging Het
Scyl3 A G 1: 163,944,867 N296S probably damaging Het
Sipa1l3 G A 7: 29,348,539 T1308M probably damaging Het
Slc39a9 A G 12: 80,644,888 D3G probably damaging Het
Slc4a9 A G 18: 36,529,687 E165G probably benign Het
Slc6a3 A T 13: 73,538,657 I48F probably benign Het
Stxbp3 C T 3: 108,802,160 C354Y probably damaging Het
Terb1 C A 8: 104,473,042 probably benign Het
Tfrc G A 16: 32,624,831 probably null Het
Toporsl A C 4: 52,611,134 R342S probably benign Het
Ttc26 T C 6: 38,385,500 L70P probably damaging Het
Ube2d3 T A 3: 135,465,217 W141R probably damaging Het
Vps13b G T 15: 35,910,340 V3417L probably benign Het
Other mutations in Olfr32
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01328:Olfr32 APN 2 90139074 missense probably benign 0.30
IGL01976:Olfr32 APN 2 90138924 missense probably damaging 1.00
IGL02076:Olfr32 APN 2 90138815 missense probably damaging 1.00
IGL03030:Olfr32 APN 2 90138662 missense possibly damaging 0.93
IGL03235:Olfr32 APN 2 90139070 missense possibly damaging 0.88
R1240:Olfr32 UTSW 2 90138813 missense possibly damaging 0.48
R1511:Olfr32 UTSW 2 90138404 missense probably benign 0.13
R1602:Olfr32 UTSW 2 90139055 missense probably damaging 1.00
R1828:Olfr32 UTSW 2 90138587 missense probably damaging 0.99
R2023:Olfr32 UTSW 2 90138856 nonsense probably null
R2177:Olfr32 UTSW 2 90138464 missense possibly damaging 0.70
R2679:Olfr32 UTSW 2 90138545 missense possibly damaging 0.93
R4490:Olfr32 UTSW 2 90138917 missense probably damaging 0.97
R4585:Olfr32 UTSW 2 90138214 missense probably benign 0.01
R4586:Olfr32 UTSW 2 90138214 missense probably benign 0.01
R4649:Olfr32 UTSW 2 90139088 missense probably damaging 0.99
R4688:Olfr32 UTSW 2 90138999 missense possibly damaging 0.80
R4694:Olfr32 UTSW 2 90138249 nonsense probably null
R5245:Olfr32 UTSW 2 90138262 missense probably damaging 1.00
R5509:Olfr32 UTSW 2 90138892 missense probably damaging 1.00
R5991:Olfr32 UTSW 2 90138234 nonsense probably null
R6004:Olfr32 UTSW 2 90138999 missense probably benign 0.32
R6128:Olfr32 UTSW 2 90138610 nonsense probably null
R6519:Olfr32 UTSW 2 90138812 missense possibly damaging 0.90
R7472:Olfr32 UTSW 2 90138324 missense probably damaging 1.00
X0066:Olfr32 UTSW 2 90138390 missense probably damaging 1.00
Posted On2016-08-02