Incidental Mutation 'R5327:Dnah7c'
| ID |
422007 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah7c
|
| Ensembl Gene |
ENSMUSG00000101337 |
| Gene Name |
dynein, axonemal, heavy chain 7C |
| Synonyms |
Dnahc7c |
| MMRRC Submission |
042910-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.371)
|
| Stock # |
R5327 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
46464752-46846636 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 46704728 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 2247
(D2247G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140430
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000189749]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189749
AA Change: D2247G
PolyPhen 2
Score 0.048 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000140430
Gene: ENSMUSG00000101337
AA Change: D2247G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
746 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
754 |
1167 |
2.2e-138 |
PFAM |
|
AAA
|
1320 |
1459 |
4e-3 |
SMART |
|
Blast:AAA
|
1601 |
1829 |
4e-87 |
BLAST |
|
AAA
|
1968 |
2116 |
8.7e-4 |
SMART |
|
Pfam:AAA_8
|
2303 |
2574 |
6.2e-73 |
PFAM |
|
Pfam:MT
|
2586 |
2935 |
5.4e-52 |
PFAM |
|
Pfam:AAA_9
|
2953 |
3183 |
7.4e-63 |
PFAM |
|
Pfam:Dynein_heavy
|
3312 |
4021 |
1.3e-250 |
PFAM |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.9%
|
| Validation Efficiency |
100% (101/101) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| AA986860 |
A |
G |
1: 130,668,740 (GRCm39) |
S36G |
probably damaging |
Het |
| Aarsd1 |
T |
C |
11: 101,301,203 (GRCm39) |
N280D |
probably benign |
Het |
| Abca2 |
T |
A |
2: 25,335,686 (GRCm39) |
M2099K |
probably damaging |
Het |
| Abcb5 |
T |
A |
12: 118,875,278 (GRCm39) |
E631D |
probably benign |
Het |
| Acss2 |
T |
A |
2: 155,415,149 (GRCm39) |
L682Q |
probably null |
Het |
| Adamts14 |
G |
A |
10: 61,034,267 (GRCm39) |
P1207L |
probably benign |
Het |
| Adora1 |
G |
A |
1: 134,130,748 (GRCm39) |
R308* |
probably null |
Het |
| Arcn1 |
A |
T |
9: 44,668,444 (GRCm39) |
V264E |
probably benign |
Het |
| B3galt1 |
G |
A |
2: 67,949,112 (GRCm39) |
G276S |
probably damaging |
Het |
| Bms1 |
A |
T |
6: 118,382,179 (GRCm39) |
M453K |
possibly damaging |
Het |
| Bnip3l |
T |
C |
14: 67,225,180 (GRCm39) |
Y218C |
probably damaging |
Het |
| Cacna2d2 |
A |
G |
9: 107,390,805 (GRCm39) |
E379G |
probably null |
Het |
| Cacng6 |
G |
A |
7: 3,483,376 (GRCm39) |
G235R |
probably damaging |
Het |
| Capn8 |
A |
T |
1: 182,456,169 (GRCm39) |
T640S |
probably benign |
Het |
| Ccdc106 |
T |
C |
7: 5,063,159 (GRCm39) |
|
probably benign |
Het |
| Ccdc33 |
A |
T |
9: 57,993,860 (GRCm39) |
N95K |
probably benign |
Het |
| Celsr3 |
T |
A |
9: 108,719,907 (GRCm39) |
|
probably benign |
Het |
| Cemip |
A |
T |
7: 83,604,509 (GRCm39) |
N844K |
probably damaging |
Het |
| Chrdl2 |
A |
T |
7: 99,677,948 (GRCm39) |
T284S |
probably damaging |
Het |
| Ckm |
A |
G |
7: 19,154,090 (GRCm39) |
Y279C |
probably damaging |
Het |
| Clvs1 |
A |
T |
4: 9,424,261 (GRCm39) |
I236F |
probably damaging |
Het |
| Col9a1 |
T |
C |
1: 24,234,620 (GRCm39) |
|
probably null |
Het |
| Csmd1 |
T |
C |
8: 17,266,728 (GRCm39) |
E66G |
possibly damaging |
Het |
| Ctdsp2 |
A |
G |
10: 126,831,923 (GRCm39) |
D26G |
probably damaging |
Het |
| Ctsll3 |
C |
A |
13: 60,946,721 (GRCm39) |
|
probably null |
Het |
| Cyp2d12 |
A |
T |
15: 82,439,423 (GRCm39) |
M26L |
probably benign |
Het |
| Cyp8b1 |
C |
T |
9: 121,743,950 (GRCm39) |
D461N |
probably damaging |
Het |
| Dbt |
A |
T |
3: 116,322,220 (GRCm39) |
|
probably benign |
Het |
| Dsg1c |
A |
G |
18: 20,400,994 (GRCm39) |
I166V |
possibly damaging |
Het |
| Duoxa1 |
T |
A |
2: 122,134,361 (GRCm39) |
E252D |
probably damaging |
Het |
| Ezr |
T |
A |
17: 7,020,448 (GRCm39) |
K211M |
probably damaging |
Het |
| Faap100 |
T |
A |
11: 120,268,458 (GRCm39) |
E105V |
possibly damaging |
Het |
| Fahd2a |
T |
C |
2: 127,283,878 (GRCm39) |
D54G |
possibly damaging |
Het |
| Fbxo9 |
A |
T |
9: 78,003,146 (GRCm39) |
|
probably null |
Het |
| Fndc1 |
A |
G |
17: 7,991,540 (GRCm39) |
S719P |
unknown |
Het |
| Gas7 |
G |
T |
11: 67,552,916 (GRCm39) |
G159C |
probably damaging |
Het |
| Gba2 |
T |
C |
4: 43,574,063 (GRCm39) |
D130G |
probably damaging |
Het |
| Gli3 |
T |
G |
13: 15,723,092 (GRCm39) |
S78A |
probably damaging |
Het |
| Gtpbp6 |
A |
G |
5: 110,254,770 (GRCm39) |
F101S |
probably damaging |
Het |
| Gzme |
G |
A |
14: 56,355,224 (GRCm39) |
H236Y |
probably benign |
Het |
| Hira |
T |
C |
16: 18,773,508 (GRCm39) |
Y943H |
probably damaging |
Het |
| Hmbox1 |
G |
A |
14: 65,134,144 (GRCm39) |
S152L |
possibly damaging |
Het |
| Ibtk |
A |
G |
9: 85,619,519 (GRCm39) |
|
probably null |
Het |
| Jade1 |
T |
C |
3: 41,568,413 (GRCm39) |
I827T |
possibly damaging |
Het |
| Jakmip3 |
A |
T |
7: 138,627,164 (GRCm39) |
E389D |
possibly damaging |
Het |
| Klhdc8b |
A |
T |
9: 108,326,241 (GRCm39) |
|
probably benign |
Het |
| Lama2 |
T |
C |
10: 27,014,942 (GRCm39) |
T1589A |
probably benign |
Het |
| Lbx2 |
A |
C |
6: 83,064,784 (GRCm39) |
K107T |
probably damaging |
Het |
| Ldha |
A |
G |
7: 46,503,522 (GRCm39) |
M259V |
probably benign |
Het |
| Lrrtm4 |
A |
G |
6: 79,999,620 (GRCm39) |
K344R |
probably damaging |
Het |
| Ltb |
A |
T |
17: 35,414,935 (GRCm39) |
E245V |
probably damaging |
Het |
| Macf1 |
GCCCCC |
GCCCCCC |
4: 123,244,784 (GRCm39) |
|
probably null |
Het |
| Map3k13 |
T |
A |
16: 21,740,397 (GRCm39) |
S575T |
possibly damaging |
Het |
| Mcpt2 |
A |
T |
14: 56,280,833 (GRCm39) |
I74F |
probably damaging |
Het |
| Mpeg1 |
T |
A |
19: 12,439,013 (GRCm39) |
V157D |
probably damaging |
Het |
| Mrpl21 |
A |
T |
19: 3,337,009 (GRCm39) |
|
probably null |
Het |
| Nagpa |
T |
C |
16: 5,017,877 (GRCm39) |
T99A |
possibly damaging |
Het |
| Nphs1 |
A |
T |
7: 30,163,250 (GRCm39) |
I469F |
probably benign |
Het |
| Nyap2 |
A |
G |
1: 81,169,756 (GRCm39) |
E171G |
possibly damaging |
Het |
| Oas1e |
A |
G |
5: 120,930,006 (GRCm39) |
Y171H |
probably damaging |
Het |
| Or10ag59 |
T |
A |
2: 87,406,043 (GRCm39) |
V205D |
probably damaging |
Het |
| Or2y1f |
T |
C |
11: 49,184,493 (GRCm39) |
L115P |
probably damaging |
Het |
| Or5ac23 |
T |
C |
16: 59,149,461 (GRCm39) |
K137R |
probably benign |
Het |
| Or5h26 |
T |
C |
16: 58,987,983 (GRCm39) |
I174M |
possibly damaging |
Het |
| Otud7b |
C |
A |
3: 96,063,055 (GRCm39) |
Q765K |
probably benign |
Het |
| Pdzd7 |
A |
G |
19: 45,017,216 (GRCm39) |
V851A |
probably benign |
Het |
| Pi4ka |
T |
G |
16: 17,143,277 (GRCm39) |
K794T |
probably damaging |
Het |
| Pkhd1l1 |
T |
A |
15: 44,410,258 (GRCm39) |
N2588K |
probably damaging |
Het |
| Pla2g6 |
A |
T |
15: 79,186,837 (GRCm39) |
M471K |
probably benign |
Het |
| Plagl2 |
T |
C |
2: 153,077,759 (GRCm39) |
H74R |
possibly damaging |
Het |
| Prf1 |
T |
A |
10: 61,136,037 (GRCm39) |
N104K |
probably benign |
Het |
| Ptprf |
A |
T |
4: 118,093,586 (GRCm39) |
I358N |
probably damaging |
Het |
| Rcsd1 |
A |
G |
1: 165,482,872 (GRCm39) |
|
probably null |
Het |
| Rev1 |
G |
A |
1: 38,147,532 (GRCm39) |
R3* |
probably null |
Het |
| Rp1 |
T |
C |
1: 4,419,583 (GRCm39) |
|
probably null |
Het |
| Rrp12 |
G |
A |
19: 41,881,035 (GRCm39) |
T132I |
probably damaging |
Het |
| Sema3a |
T |
C |
5: 13,649,357 (GRCm39) |
V702A |
probably benign |
Het |
| Serpinb12 |
A |
G |
1: 106,884,174 (GRCm39) |
N307D |
probably damaging |
Het |
| Slc35d1 |
A |
G |
4: 103,070,383 (GRCm39) |
L103P |
probably damaging |
Het |
| Smyd4 |
T |
C |
11: 75,281,765 (GRCm39) |
C413R |
probably damaging |
Het |
| Stab1 |
G |
A |
14: 30,883,793 (GRCm39) |
Q255* |
probably null |
Het |
| Synpo |
T |
A |
18: 60,736,918 (GRCm39) |
I343F |
possibly damaging |
Het |
| Tcirg1 |
A |
G |
19: 3,952,342 (GRCm39) |
|
probably null |
Het |
| Tmem132c |
A |
G |
5: 127,640,816 (GRCm39) |
T996A |
possibly damaging |
Het |
| Trim10 |
A |
G |
17: 37,181,081 (GRCm39) |
E104G |
probably damaging |
Het |
| Trpc1 |
T |
C |
9: 95,603,524 (GRCm39) |
|
probably null |
Het |
| Tspo2 |
A |
T |
17: 48,756,887 (GRCm39) |
|
probably benign |
Het |
| Ugt2a3 |
A |
T |
5: 87,479,174 (GRCm39) |
I258N |
probably damaging |
Het |
| Usp34 |
T |
C |
11: 23,418,846 (GRCm39) |
L2998P |
probably damaging |
Het |
| Vmn1r45 |
A |
C |
6: 89,910,123 (GRCm39) |
D162E |
possibly damaging |
Het |
| Vmn2r117 |
A |
T |
17: 23,696,848 (GRCm39) |
Y186* |
probably null |
Het |
| Vmn2r67 |
A |
G |
7: 84,785,698 (GRCm39) |
F769S |
probably damaging |
Het |
| Zbtb17 |
A |
G |
4: 141,192,942 (GRCm39) |
I514V |
probably benign |
Het |
| Zfp329 |
A |
C |
7: 12,545,421 (GRCm39) |
D34E |
probably benign |
Het |
|
| Other mutations in Dnah7c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00559:Dnah7c
|
APN |
1 |
46,846,449 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02958:Dnah7c
|
APN |
1 |
46,696,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03035:Dnah7c
|
APN |
1 |
46,563,277 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03161:Dnah7c
|
APN |
1 |
46,506,456 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03178:Dnah7c
|
APN |
1 |
46,506,525 (GRCm39) |
missense |
probably benign |
|
|
IGL03052:Dnah7c
|
UTSW |
1 |
46,671,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dnah7c
|
UTSW |
1 |
46,505,065 (GRCm39) |
missense |
probably benign |
|
|
R1029:Dnah7c
|
UTSW |
1 |
46,651,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Dnah7c
|
UTSW |
1 |
46,837,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3977:Dnah7c
|
UTSW |
1 |
46,668,071 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4003:Dnah7c
|
UTSW |
1 |
46,720,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Dnah7c
|
UTSW |
1 |
46,705,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4303:Dnah7c
|
UTSW |
1 |
46,787,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4329:Dnah7c
|
UTSW |
1 |
46,688,441 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4434:Dnah7c
|
UTSW |
1 |
46,705,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Dnah7c
|
UTSW |
1 |
46,779,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Dnah7c
|
UTSW |
1 |
46,787,795 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4507:Dnah7c
|
UTSW |
1 |
46,805,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4527:Dnah7c
|
UTSW |
1 |
46,572,091 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4571:Dnah7c
|
UTSW |
1 |
46,572,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4589:Dnah7c
|
UTSW |
1 |
46,553,743 (GRCm39) |
nonsense |
probably null |
|
|
R4731:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4732:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Dnah7c
|
UTSW |
1 |
46,572,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4845:Dnah7c
|
UTSW |
1 |
46,832,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4875:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4916:Dnah7c
|
UTSW |
1 |
46,634,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5241:Dnah7c
|
UTSW |
1 |
46,569,660 (GRCm39) |
missense |
probably benign |
|
|
R5279:Dnah7c
|
UTSW |
1 |
46,558,429 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5546:Dnah7c
|
UTSW |
1 |
46,705,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Dnah7c
|
UTSW |
1 |
46,837,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5637:Dnah7c
|
UTSW |
1 |
46,799,521 (GRCm39) |
splice site |
probably null |
|
|
R5639:Dnah7c
|
UTSW |
1 |
46,778,828 (GRCm39) |
missense |
probably benign |
|
|
R5663:Dnah7c
|
UTSW |
1 |
46,574,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Dnah7c
|
UTSW |
1 |
46,787,826 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5759:Dnah7c
|
UTSW |
1 |
46,654,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5771:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5784:Dnah7c
|
UTSW |
1 |
46,563,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5800:Dnah7c
|
UTSW |
1 |
46,686,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5933:Dnah7c
|
UTSW |
1 |
46,558,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5948:Dnah7c
|
UTSW |
1 |
46,711,657 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Dnah7c
|
UTSW |
1 |
46,808,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Dnah7c
|
UTSW |
1 |
46,697,450 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,554,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6714:Dnah7c
|
UTSW |
1 |
46,779,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6729:Dnah7c
|
UTSW |
1 |
46,711,681 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6763:Dnah7c
|
UTSW |
1 |
46,668,050 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6866:Dnah7c
|
UTSW |
1 |
46,696,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Dnah7c
|
UTSW |
1 |
46,566,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6988:Dnah7c
|
UTSW |
1 |
46,705,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6995:Dnah7c
|
UTSW |
1 |
46,494,973 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7007:Dnah7c
|
UTSW |
1 |
46,571,910 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7086:Dnah7c
|
UTSW |
1 |
46,789,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Dnah7c
|
UTSW |
1 |
46,566,645 (GRCm39) |
missense |
probably benign |
|
|
R7131:Dnah7c
|
UTSW |
1 |
46,720,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7135:Dnah7c
|
UTSW |
1 |
46,572,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Dnah7c
|
UTSW |
1 |
46,719,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7176:Dnah7c
|
UTSW |
1 |
46,469,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7221:Dnah7c
|
UTSW |
1 |
46,494,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7310:Dnah7c
|
UTSW |
1 |
46,636,127 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,819,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,823,608 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7404:Dnah7c
|
UTSW |
1 |
46,705,223 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7452:Dnah7c
|
UTSW |
1 |
46,686,196 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7515:Dnah7c
|
UTSW |
1 |
46,496,450 (GRCm39) |
missense |
probably benign |
|
|
R7534:Dnah7c
|
UTSW |
1 |
46,809,227 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7542:Dnah7c
|
UTSW |
1 |
46,823,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7605:Dnah7c
|
UTSW |
1 |
46,671,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Dnah7c
|
UTSW |
1 |
46,641,973 (GRCm39) |
missense |
probably benign |
|
|
R7770:Dnah7c
|
UTSW |
1 |
46,665,460 (GRCm39) |
splice site |
probably null |
|
|
R7884:Dnah7c
|
UTSW |
1 |
46,830,929 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7899:Dnah7c
|
UTSW |
1 |
46,553,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dnah7c
|
UTSW |
1 |
46,496,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8057:Dnah7c
|
UTSW |
1 |
46,728,112 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8191:Dnah7c
|
UTSW |
1 |
46,646,618 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8255:Dnah7c
|
UTSW |
1 |
46,698,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8428:Dnah7c
|
UTSW |
1 |
46,711,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Dnah7c
|
UTSW |
1 |
46,572,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Dnah7c
|
UTSW |
1 |
46,719,952 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8559:Dnah7c
|
UTSW |
1 |
46,764,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8752:Dnah7c
|
UTSW |
1 |
46,711,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8869:Dnah7c
|
UTSW |
1 |
46,671,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9058:Dnah7c
|
UTSW |
1 |
46,805,816 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,816,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,704,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9246:Dnah7c
|
UTSW |
1 |
46,571,934 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9319:Dnah7c
|
UTSW |
1 |
46,521,168 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9388:Dnah7c
|
UTSW |
1 |
46,779,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,654,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,506,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,799,476 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,686,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Dnah7c
|
UTSW |
1 |
46,693,263 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCGTATGCTTCTAATACAACTTTG -3'
(R):5'- TTATATTCATCCAGATGGCCTTCG -3'
Sequencing Primer
(F):5'- CTCAGAGTATATTATGATCGCC -3'
(R):5'- AGATGGCCTTCGACAATCATCCTG -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation