Mutagenetix > Incidental Mutation

Incidental Mutation 'R5327:Csmd1'

422050

Institutional Source

Beutler Lab

Gene Symbol

Csmd1

Ensembl Gene

ENSMUSG00000060924

Gene Name

CUB and Sushi multiple domains 1

Synonyms

MMRRC Submission

042910-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5327 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

15942537-17585602 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 17266728 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 66 (E66G)

Ref Sequence

ENSEMBL: ENSMUSP00000080751 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082104]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000082104
AA Change: E66G

PolyPhen 2 Score 0.942 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000080751
Gene: ENSMUSG00000060924
AA Change: E66G

Domain	Start	End	E-Value	Type
signal peptide	1	29	N/A	INTRINSIC
CUB	32	140	1.46e-26	SMART
CCP	145	202	1.01e-11	SMART
CUB	208	312	1.05e-27	SMART
CCP	349	406	1.28e-8	SMART
CUB	411	522	2.34e-25	SMART
CCP	527	580	1.22e-14	SMART
CUB	584	692	1.61e-37	SMART
CCP	697	754	4.41e-12	SMART
CUB	758	866	6.55e-38	SMART
CCP	873	926	2.53e-12	SMART
CUB	930	1040	8.94e-22	SMART
CCP	1045	1100	7.06e-11	SMART
CUB	1104	1212	3.14e-26	SMART
CCP	1217	1273	1.18e-12	SMART
CUB	1277	1386	9.72e-32	SMART
CCP	1391	1447	2.06e-12	SMART
CUB	1451	1559	1.68e-35	SMART
CCP	1564	1621	2.53e-12	SMART
CUB	1625	1733	4.24e-14	SMART
CCP	1741	1798	9.46e-12	SMART
CUB	1802	1910	4.23e-32	SMART
CCP	1915	1970	8.23e-12	SMART
CUB	1974	2082	8.59e-33	SMART
CCP	2087	2142	6.09e-15	SMART
CUB	2146	2253	2.36e-30	SMART
CCP	2258	2315	1.1e-12	SMART
CUB	2320	2430	4.3e-24	SMART
CCP	2432	2490	2.94e-8	SMART
CCP	2495	2552	2.03e-11	SMART
CCP	2557	2617	1.22e-5	SMART
CCP	2622	2675	2.72e-12	SMART
CCP	2680	2733	5.86e-17	SMART
CCP	2738	2791	6.09e-15	SMART
CCP	2796	2854	9.1e-14	SMART
CCP	2859	2912	3.96e-14	SMART
CCP	2920	2973	4.41e-12	SMART
CCP	2978	3032	2.94e-8	SMART
CCP	3037	3092	6.59e-11	SMART
CCP	3097	3150	4.12e-12	SMART
CCP	3155	3208	7.92e-14	SMART
CCP	3216	3270	2.8e-14	SMART
CCP	3275	3330	3.78e-11	SMART
transmembrane domain	3487	3509	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000131778

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000133933

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000137947

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000138348

Meta Mutation Damage Score

0.1747

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.5%
20x: 95.9%

Validation Efficiency

100% (101/101)

MGI Phenotype

PHENOTYPE: Mice exhibit normal pre-pulse inhibition, social interaction, sucrose preference and d-amphetamine sensitivity. [provided by MGI curators]

Allele List at MGI

All alleles(1) : Targeted, knock-out(1)

Other mutations in this stock

Total: 94 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AA986860	A	G	1: 130,668,740 (GRCm39)	S36G	probably damaging	Het
Aarsd1	T	C	11: 101,301,203 (GRCm39)	N280D	probably benign	Het
Abca2	T	A	2: 25,335,686 (GRCm39)	M2099K	probably damaging	Het
Abcb5	T	A	12: 118,875,278 (GRCm39)	E631D	probably benign	Het
Acss2	T	A	2: 155,415,149 (GRCm39)	L682Q	probably null	Het
Adamts14	G	A	10: 61,034,267 (GRCm39)	P1207L	probably benign	Het
Adora1	G	A	1: 134,130,748 (GRCm39)	R308*	probably null	Het
Arcn1	A	T	9: 44,668,444 (GRCm39)	V264E	probably benign	Het
B3galt1	G	A	2: 67,949,112 (GRCm39)	G276S	probably damaging	Het
Bms1	A	T	6: 118,382,179 (GRCm39)	M453K	possibly damaging	Het
Bnip3l	T	C	14: 67,225,180 (GRCm39)	Y218C	probably damaging	Het
Cacna2d2	A	G	9: 107,390,805 (GRCm39)	E379G	probably null	Het
Cacng6	G	A	7: 3,483,376 (GRCm39)	G235R	probably damaging	Het
Capn8	A	T	1: 182,456,169 (GRCm39)	T640S	probably benign	Het
Ccdc106	T	C	7: 5,063,159 (GRCm39)		probably benign	Het
Ccdc33	A	T	9: 57,993,860 (GRCm39)	N95K	probably benign	Het
Celsr3	T	A	9: 108,719,907 (GRCm39)		probably benign	Het
Cemip	A	T	7: 83,604,509 (GRCm39)	N844K	probably damaging	Het
Chrdl2	A	T	7: 99,677,948 (GRCm39)	T284S	probably damaging	Het
Ckm	A	G	7: 19,154,090 (GRCm39)	Y279C	probably damaging	Het
Clvs1	A	T	4: 9,424,261 (GRCm39)	I236F	probably damaging	Het
Col9a1	T	C	1: 24,234,620 (GRCm39)		probably null	Het
Ctdsp2	A	G	10: 126,831,923 (GRCm39)	D26G	probably damaging	Het
Ctsll3	C	A	13: 60,946,721 (GRCm39)		probably null	Het
Cyp2d12	A	T	15: 82,439,423 (GRCm39)	M26L	probably benign	Het
Cyp8b1	C	T	9: 121,743,950 (GRCm39)	D461N	probably damaging	Het
Dbt	A	T	3: 116,322,220 (GRCm39)		probably benign	Het
Dnah7c	A	G	1: 46,704,728 (GRCm39)	D2247G	probably benign	Het
Dsg1c	A	G	18: 20,400,994 (GRCm39)	I166V	possibly damaging	Het
Duoxa1	T	A	2: 122,134,361 (GRCm39)	E252D	probably damaging	Het
Ezr	T	A	17: 7,020,448 (GRCm39)	K211M	probably damaging	Het
Faap100	T	A	11: 120,268,458 (GRCm39)	E105V	possibly damaging	Het
Fahd2a	T	C	2: 127,283,878 (GRCm39)	D54G	possibly damaging	Het
Fbxo9	A	T	9: 78,003,146 (GRCm39)		probably null	Het
Fndc1	A	G	17: 7,991,540 (GRCm39)	S719P	unknown	Het
Gas7	G	T	11: 67,552,916 (GRCm39)	G159C	probably damaging	Het
Gba2	T	C	4: 43,574,063 (GRCm39)	D130G	probably damaging	Het
Gli3	T	G	13: 15,723,092 (GRCm39)	S78A	probably damaging	Het
Gtpbp6	A	G	5: 110,254,770 (GRCm39)	F101S	probably damaging	Het
Gzme	G	A	14: 56,355,224 (GRCm39)	H236Y	probably benign	Het
Hira	T	C	16: 18,773,508 (GRCm39)	Y943H	probably damaging	Het
Hmbox1	G	A	14: 65,134,144 (GRCm39)	S152L	possibly damaging	Het
Ibtk	A	G	9: 85,619,519 (GRCm39)		probably null	Het
Jade1	T	C	3: 41,568,413 (GRCm39)	I827T	possibly damaging	Het
Jakmip3	A	T	7: 138,627,164 (GRCm39)	E389D	possibly damaging	Het
Klhdc8b	A	T	9: 108,326,241 (GRCm39)		probably benign	Het
Lama2	T	C	10: 27,014,942 (GRCm39)	T1589A	probably benign	Het
Lbx2	A	C	6: 83,064,784 (GRCm39)	K107T	probably damaging	Het
Ldha	A	G	7: 46,503,522 (GRCm39)	M259V	probably benign	Het
Lrrtm4	A	G	6: 79,999,620 (GRCm39)	K344R	probably damaging	Het
Ltb	A	T	17: 35,414,935 (GRCm39)	E245V	probably damaging	Het
Macf1	GCCCCC	GCCCCCC	4: 123,244,784 (GRCm39)		probably null	Het
Map3k13	T	A	16: 21,740,397 (GRCm39)	S575T	possibly damaging	Het
Mcpt2	A	T	14: 56,280,833 (GRCm39)	I74F	probably damaging	Het
Mpeg1	T	A	19: 12,439,013 (GRCm39)	V157D	probably damaging	Het
Mrpl21	A	T	19: 3,337,009 (GRCm39)		probably null	Het
Nagpa	T	C	16: 5,017,877 (GRCm39)	T99A	possibly damaging	Het
Nphs1	A	T	7: 30,163,250 (GRCm39)	I469F	probably benign	Het
Nyap2	A	G	1: 81,169,756 (GRCm39)	E171G	possibly damaging	Het
Oas1e	A	G	5: 120,930,006 (GRCm39)	Y171H	probably damaging	Het
Or10ag59	T	A	2: 87,406,043 (GRCm39)	V205D	probably damaging	Het
Or2y1f	T	C	11: 49,184,493 (GRCm39)	L115P	probably damaging	Het
Or5ac23	T	C	16: 59,149,461 (GRCm39)	K137R	probably benign	Het
Or5h26	T	C	16: 58,987,983 (GRCm39)	I174M	possibly damaging	Het
Otud7b	C	A	3: 96,063,055 (GRCm39)	Q765K	probably benign	Het
Pdzd7	A	G	19: 45,017,216 (GRCm39)	V851A	probably benign	Het
Pi4ka	T	G	16: 17,143,277 (GRCm39)	K794T	probably damaging	Het
Pkhd1l1	T	A	15: 44,410,258 (GRCm39)	N2588K	probably damaging	Het
Pla2g6	A	T	15: 79,186,837 (GRCm39)	M471K	probably benign	Het
Plagl2	T	C	2: 153,077,759 (GRCm39)	H74R	possibly damaging	Het
Prf1	T	A	10: 61,136,037 (GRCm39)	N104K	probably benign	Het
Ptprf	A	T	4: 118,093,586 (GRCm39)	I358N	probably damaging	Het
Rcsd1	A	G	1: 165,482,872 (GRCm39)		probably null	Het
Rev1	G	A	1: 38,147,532 (GRCm39)	R3*	probably null	Het
Rp1	T	C	1: 4,419,583 (GRCm39)		probably null	Het
Rrp12	G	A	19: 41,881,035 (GRCm39)	T132I	probably damaging	Het
Sema3a	T	C	5: 13,649,357 (GRCm39)	V702A	probably benign	Het
Serpinb12	A	G	1: 106,884,174 (GRCm39)	N307D	probably damaging	Het
Slc35d1	A	G	4: 103,070,383 (GRCm39)	L103P	probably damaging	Het
Smyd4	T	C	11: 75,281,765 (GRCm39)	C413R	probably damaging	Het
Stab1	G	A	14: 30,883,793 (GRCm39)	Q255*	probably null	Het
Synpo	T	A	18: 60,736,918 (GRCm39)	I343F	possibly damaging	Het
Tcirg1	A	G	19: 3,952,342 (GRCm39)		probably null	Het
Tmem132c	A	G	5: 127,640,816 (GRCm39)	T996A	possibly damaging	Het
Trim10	A	G	17: 37,181,081 (GRCm39)	E104G	probably damaging	Het
Trpc1	T	C	9: 95,603,524 (GRCm39)		probably null	Het
Tspo2	A	T	17: 48,756,887 (GRCm39)		probably benign	Het
Ugt2a3	A	T	5: 87,479,174 (GRCm39)	I258N	probably damaging	Het
Usp34	T	C	11: 23,418,846 (GRCm39)	L2998P	probably damaging	Het
Vmn1r45	A	C	6: 89,910,123 (GRCm39)	D162E	possibly damaging	Het
Vmn2r117	A	T	17: 23,696,848 (GRCm39)	Y186*	probably null	Het
Vmn2r67	A	G	7: 84,785,698 (GRCm39)	F769S	probably damaging	Het
Zbtb17	A	G	4: 141,192,942 (GRCm39)	I514V	probably benign	Het
Zfp329	A	C	7: 12,545,421 (GRCm39)	D34E	probably benign	Het

Other mutations in Csmd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00095:Csmd1	APN	8	16,059,297 (GRCm39)	splice site	probably benign
IGL00433:Csmd1	APN	8	16,281,387 (GRCm39)	missense	probably damaging	1.00
IGL00500:Csmd1	APN	8	15,971,139 (GRCm39)	missense	probably damaging	1.00
IGL00666:Csmd1	APN	8	16,240,004 (GRCm39)	missense	probably damaging	1.00
IGL00913:Csmd1	APN	8	16,121,301 (GRCm39)	missense	probably benign	0.00
IGL01012:Csmd1	APN	8	15,967,341 (GRCm39)	missense	probably benign	0.00
IGL01123:Csmd1	APN	8	17,584,944 (GRCm39)	missense	possibly damaging	0.96
IGL01348:Csmd1	APN	8	15,960,596 (GRCm39)	missense	probably damaging	0.99
IGL01444:Csmd1	APN	8	16,250,069 (GRCm39)	missense	probably benign	0.00
IGL01530:Csmd1	APN	8	15,953,195 (GRCm39)	missense	probably damaging	0.99
IGL01548:Csmd1	APN	8	16,338,660 (GRCm39)	nonsense	probably null
IGL01814:Csmd1	APN	8	16,551,389 (GRCm39)	missense	probably damaging	1.00
IGL01889:Csmd1	APN	8	16,048,857 (GRCm39)	missense	probably damaging	1.00
IGL02055:Csmd1	APN	8	16,119,015 (GRCm39)	missense	probably damaging	0.99
IGL02066:Csmd1	APN	8	15,976,594 (GRCm39)	missense	probably damaging	1.00
IGL02097:Csmd1	APN	8	16,261,773 (GRCm39)	missense	probably null	0.17
IGL02112:Csmd1	APN	8	16,131,719 (GRCm39)	missense	probably benign	0.18
IGL02161:Csmd1	APN	8	16,408,426 (GRCm39)	missense	probably damaging	0.97
IGL02189:Csmd1	APN	8	16,321,620 (GRCm39)	missense	probably damaging	0.99
IGL02272:Csmd1	APN	8	16,249,907 (GRCm39)	missense	probably damaging	0.99
IGL02292:Csmd1	APN	8	16,261,884 (GRCm39)	missense	probably damaging	1.00
IGL02385:Csmd1	APN	8	15,953,275 (GRCm39)	missense	probably benign	0.08
IGL02424:Csmd1	APN	8	16,142,340 (GRCm39)	missense	probably benign	0.22
IGL02492:Csmd1	APN	8	16,052,597 (GRCm39)	missense	probably benign	0.13
IGL02507:Csmd1	APN	8	17,584,992 (GRCm39)	utr 5 prime	probably benign
IGL02513:Csmd1	APN	8	16,049,869 (GRCm39)	splice site	probably benign
IGL02727:Csmd1	APN	8	16,281,341 (GRCm39)	missense	probably damaging	1.00
IGL02728:Csmd1	APN	8	16,049,779 (GRCm39)	critical splice donor site	probably null
IGL02852:Csmd1	APN	8	15,945,728 (GRCm39)	missense	probably damaging	0.99
IGL02935:Csmd1	APN	8	16,273,348 (GRCm39)	missense	probably damaging	1.00
IGL02945:Csmd1	APN	8	16,321,584 (GRCm39)	missense	possibly damaging	0.92
IGL02959:Csmd1	APN	8	15,960,465 (GRCm39)	missense	probably damaging	0.99
IGL03113:Csmd1	APN	8	16,078,712 (GRCm39)	missense	probably benign
IGL03129:Csmd1	APN	8	16,011,521 (GRCm39)	missense	probably damaging	0.99
IGL03131:Csmd1	APN	8	16,138,231 (GRCm39)	missense	probably damaging	1.00
IGL03275:Csmd1	APN	8	16,207,106 (GRCm39)	missense	probably benign	0.00
IGL03297:Csmd1	APN	8	16,059,432 (GRCm39)	nonsense	probably null
ikura	UTSW	8	16,281,285 (GRCm39)	missense	probably damaging	1.00
I2289:Csmd1	UTSW	8	15,962,381 (GRCm39)	missense	probably benign	0.10
IGL03055:Csmd1	UTSW	8	16,145,515 (GRCm39)	missense	probably damaging	1.00
IGL03097:Csmd1	UTSW	8	15,995,127 (GRCm39)	missense	probably damaging	1.00
PIT4260001:Csmd1	UTSW	8	16,120,327 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Csmd1	UTSW	8	15,945,728 (GRCm39)	missense	probably damaging	0.99
PIT4520001:Csmd1	UTSW	8	15,956,023 (GRCm39)	missense	probably benign	0.01
R0037:Csmd1	UTSW	8	15,967,248 (GRCm39)	missense	probably damaging	0.97
R0095:Csmd1	UTSW	8	16,283,065 (GRCm39)	missense	probably damaging	1.00
R0113:Csmd1	UTSW	8	16,034,849 (GRCm39)	missense	probably damaging	1.00
R0129:Csmd1	UTSW	8	16,129,956 (GRCm39)	missense	possibly damaging	0.95
R0144:Csmd1	UTSW	8	16,441,838 (GRCm39)	missense	probably benign	0.16
R0166:Csmd1	UTSW	8	16,283,036 (GRCm39)	missense	probably benign	0.29
R0227:Csmd1	UTSW	8	16,441,836 (GRCm39)	missense	probably benign	0.05
R0279:Csmd1	UTSW	8	16,273,249 (GRCm39)	missense	probably damaging	0.99
R0280:Csmd1	UTSW	8	16,321,616 (GRCm39)	missense	probably damaging	1.00
R0312:Csmd1	UTSW	8	16,034,760 (GRCm39)	missense	probably damaging	1.00
R0355:Csmd1	UTSW	8	15,968,330 (GRCm39)	missense	probably damaging	0.97
R0367:Csmd1	UTSW	8	15,967,270 (GRCm39)	missense	probably damaging	1.00
R0395:Csmd1	UTSW	8	16,396,652 (GRCm39)	missense	probably damaging	0.99
R0413:Csmd1	UTSW	8	16,760,530 (GRCm39)	missense	probably damaging	0.97
R0457:Csmd1	UTSW	8	16,551,407 (GRCm39)	critical splice acceptor site	probably null
R0463:Csmd1	UTSW	8	15,971,759 (GRCm39)	missense	probably damaging	0.99
R0482:Csmd1	UTSW	8	16,283,115 (GRCm39)	missense	probably damaging	1.00
R0501:Csmd1	UTSW	8	17,077,339 (GRCm39)	missense	probably damaging	0.97
R0505:Csmd1	UTSW	8	16,042,758 (GRCm39)	missense	probably damaging	1.00
R0507:Csmd1	UTSW	8	16,235,358 (GRCm39)	splice site	probably benign
R0511:Csmd1	UTSW	8	15,982,529 (GRCm39)	missense	possibly damaging	0.80
R0555:Csmd1	UTSW	8	16,235,287 (GRCm39)	missense	probably benign
R0580:Csmd1	UTSW	8	15,960,528 (GRCm39)	missense	probably damaging	1.00
R0610:Csmd1	UTSW	8	15,968,208 (GRCm39)	missense	possibly damaging	0.95
R0634:Csmd1	UTSW	8	16,276,405 (GRCm39)	missense	probably damaging	1.00
R0666:Csmd1	UTSW	8	16,119,063 (GRCm39)	missense	possibly damaging	0.88
R0674:Csmd1	UTSW	8	16,050,550 (GRCm39)	missense	probably benign	0.03
R0675:Csmd1	UTSW	8	16,208,145 (GRCm39)	missense	probably benign	0.01
R0763:Csmd1	UTSW	8	17,077,300 (GRCm39)	missense	possibly damaging	0.67
R0781:Csmd1	UTSW	8	15,971,174 (GRCm39)	missense	probably benign	0.35
R0862:Csmd1	UTSW	8	16,240,040 (GRCm39)	missense	probably damaging	0.99
R0864:Csmd1	UTSW	8	16,240,040 (GRCm39)	missense	probably damaging	0.99
R0925:Csmd1	UTSW	8	16,760,634 (GRCm39)	missense	probably benign	0.29
R0926:Csmd1	UTSW	8	16,083,590 (GRCm39)	splice site	probably null
R1005:Csmd1	UTSW	8	16,338,707 (GRCm39)	missense	probably damaging	0.99
R1073:Csmd1	UTSW	8	16,408,477 (GRCm39)	splice site	probably benign
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1256:Csmd1	UTSW	8	16,129,978 (GRCm39)	missense	probably damaging	1.00
R1294:Csmd1	UTSW	8	16,748,052 (GRCm39)	missense	probably damaging	0.99
R1375:Csmd1	UTSW	8	16,513,095 (GRCm39)	splice site	probably null
R1447:Csmd1	UTSW	8	15,975,306 (GRCm39)	nonsense	probably null
R1450:Csmd1	UTSW	8	15,995,180 (GRCm39)	critical splice acceptor site	probably null
R1470:Csmd1	UTSW	8	16,207,218 (GRCm39)	splice site	probably benign
R1580:Csmd1	UTSW	8	15,975,299 (GRCm39)	missense	probably damaging	1.00
R1591:Csmd1	UTSW	8	15,950,710 (GRCm39)	missense	probably damaging	0.99
R1658:Csmd1	UTSW	8	16,131,739 (GRCm39)	missense	possibly damaging	0.69
R1678:Csmd1	UTSW	8	15,968,252 (GRCm39)	missense	possibly damaging	0.58
R1717:Csmd1	UTSW	8	17,266,708 (GRCm39)	missense	possibly damaging	0.58
R1735:Csmd1	UTSW	8	15,982,610 (GRCm39)	missense	probably damaging	0.99
R1750:Csmd1	UTSW	8	15,967,303 (GRCm39)	missense	probably damaging	0.99
R1753:Csmd1	UTSW	8	16,207,134 (GRCm39)	nonsense	probably null
R1822:Csmd1	UTSW	8	16,273,340 (GRCm39)	missense	probably damaging	1.00
R1875:Csmd1	UTSW	8	15,979,101 (GRCm39)	missense	probably damaging	0.99
R1909:Csmd1	UTSW	8	15,956,116 (GRCm39)	missense	probably damaging	1.00
R1912:Csmd1	UTSW	8	16,284,012 (GRCm39)	critical splice donor site	probably null
R1993:Csmd1	UTSW	8	16,396,698 (GRCm39)	missense	probably damaging	0.99
R2067:Csmd1	UTSW	8	15,950,782 (GRCm39)	missense	probably benign
R2094:Csmd1	UTSW	8	16,129,992 (GRCm39)	missense	probably damaging	0.99
R2119:Csmd1	UTSW	8	17,266,749 (GRCm39)	missense	probably damaging	0.98
R2127:Csmd1	UTSW	8	15,967,392 (GRCm39)	missense	probably damaging	1.00
R2138:Csmd1	UTSW	8	15,979,088 (GRCm39)	missense	probably damaging	0.96
R2216:Csmd1	UTSW	8	17,077,355 (GRCm39)	critical splice acceptor site	probably null
R2220:Csmd1	UTSW	8	16,042,641 (GRCm39)	missense	possibly damaging	0.94
R2380:Csmd1	UTSW	8	16,240,101 (GRCm39)	missense	probably damaging	1.00
R2471:Csmd1	UTSW	8	16,261,776 (GRCm39)	missense	probably damaging	1.00
R2984:Csmd1	UTSW	8	16,003,782 (GRCm39)	missense	probably damaging	1.00
R3001:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3002:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3003:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3103:Csmd1	UTSW	8	15,967,405 (GRCm39)	missense	probably damaging	1.00
R3104:Csmd1	UTSW	8	17,077,247 (GRCm39)	missense	probably damaging	1.00
R3620:Csmd1	UTSW	8	16,042,684 (GRCm39)	missense	probably benign	0.29
R3621:Csmd1	UTSW	8	16,042,684 (GRCm39)	missense	probably benign	0.29
R3748:Csmd1	UTSW	8	15,956,071 (GRCm39)	missense	probably damaging	0.99
R3780:Csmd1	UTSW	8	16,252,000 (GRCm39)	missense	probably damaging	1.00
R3815:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3816:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3818:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3819:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3850:Csmd1	UTSW	8	16,129,936 (GRCm39)	missense	probably benign	0.00
R3945:Csmd1	UTSW	8	15,960,619 (GRCm39)	splice site	probably null
R3980:Csmd1	UTSW	8	15,956,056 (GRCm39)	nonsense	probably null
R4061:Csmd1	UTSW	8	15,995,158 (GRCm39)	missense	probably benign	0.00
R4086:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4087:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4089:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4183:Csmd1	UTSW	8	15,960,464 (GRCm39)	missense	probably damaging	0.99
R4226:Csmd1	UTSW	8	16,050,490 (GRCm39)	missense	probably damaging	0.99
R4454:Csmd1	UTSW	8	15,995,011 (GRCm39)	missense	probably damaging	0.99
R4533:Csmd1	UTSW	8	15,981,037 (GRCm39)	splice site	probably null
R4544:Csmd1	UTSW	8	16,760,652 (GRCm39)	missense	possibly damaging	0.93
R4547:Csmd1	UTSW	8	16,441,811 (GRCm39)	missense	possibly damaging	0.48
R4612:Csmd1	UTSW	8	15,971,908 (GRCm39)	splice site	probably null
R4620:Csmd1	UTSW	8	16,052,694 (GRCm39)	critical splice acceptor site	probably null
R4627:Csmd1	UTSW	8	16,747,933 (GRCm39)	missense	probably benign	0.00
R4633:Csmd1	UTSW	8	16,052,620 (GRCm39)	missense	probably damaging	0.99
R4646:Csmd1	UTSW	8	15,982,511 (GRCm39)	missense	possibly damaging	0.87
R4648:Csmd1	UTSW	8	16,048,788 (GRCm39)	nonsense	probably null
R4668:Csmd1	UTSW	8	16,073,905 (GRCm39)	missense	possibly damaging	0.50
R4709:Csmd1	UTSW	8	16,760,522 (GRCm39)	critical splice donor site	probably null
R4709:Csmd1	UTSW	8	16,073,905 (GRCm39)	missense	possibly damaging	0.96
R4741:Csmd1	UTSW	8	15,960,447 (GRCm39)	missense	probably damaging	0.99
R4774:Csmd1	UTSW	8	16,059,369 (GRCm39)	missense	probably benign	0.11
R4793:Csmd1	UTSW	8	16,138,277 (GRCm39)	missense	probably damaging	1.00
R4829:Csmd1	UTSW	8	16,177,310 (GRCm39)	missense	probably damaging	1.00
R4888:Csmd1	UTSW	8	15,945,674 (GRCm39)	utr 3 prime	probably benign
R4896:Csmd1	UTSW	8	16,059,439 (GRCm39)	missense	probably benign	0.00
R4932:Csmd1	UTSW	8	16,073,779 (GRCm39)	missense	probably damaging	0.99
R4944:Csmd1	UTSW	8	16,048,772 (GRCm39)	missense	probably damaging	1.00
R4953:Csmd1	UTSW	8	16,249,931 (GRCm39)	missense	probably damaging	0.99
R4996:Csmd1	UTSW	8	15,960,452 (GRCm39)	missense	probably damaging	0.97
R5028:Csmd1	UTSW	8	16,039,090 (GRCm39)	missense	probably damaging	1.00
R5146:Csmd1	UTSW	8	16,246,204 (GRCm39)	missense	probably damaging	1.00
R5272:Csmd1	UTSW	8	16,249,958 (GRCm39)	missense	probably damaging	0.99
R5399:Csmd1	UTSW	8	16,760,613 (GRCm39)	missense	probably damaging	1.00
R5411:Csmd1	UTSW	8	15,960,471 (GRCm39)	missense	probably damaging	1.00
R5462:Csmd1	UTSW	8	16,011,486 (GRCm39)	missense	probably benign	0.12
R5463:Csmd1	UTSW	8	16,034,860 (GRCm39)	missense	probably benign	0.34
R5497:Csmd1	UTSW	8	16,135,195 (GRCm39)	missense	probably benign	0.20
R5536:Csmd1	UTSW	8	16,338,674 (GRCm39)	missense	probably damaging	0.99
R5711:Csmd1	UTSW	8	16,003,703 (GRCm39)	missense	probably damaging	1.00
R5730:Csmd1	UTSW	8	16,235,206 (GRCm39)	nonsense	probably null
R5788:Csmd1	UTSW	8	16,251,980 (GRCm39)	missense	probably damaging	1.00
R5941:Csmd1	UTSW	8	15,982,471 (GRCm39)	missense	probably damaging	0.99
R5960:Csmd1	UTSW	8	16,121,430 (GRCm39)	missense	possibly damaging	0.68
R5961:Csmd1	UTSW	8	16,120,366 (GRCm39)	missense	probably damaging	0.99
R5969:Csmd1	UTSW	8	16,121,367 (GRCm39)	missense	probably benign	0.00
R5998:Csmd1	UTSW	8	15,960,443 (GRCm39)	missense	probably damaging	1.00
R6062:Csmd1	UTSW	8	16,142,319 (GRCm39)	missense	possibly damaging	0.68
R6109:Csmd1	UTSW	8	16,249,874 (GRCm39)	missense	possibly damaging	0.93
R6116:Csmd1	UTSW	8	16,261,864 (GRCm39)	missense	probably damaging	1.00
R6143:Csmd1	UTSW	8	16,138,315 (GRCm39)	missense	probably damaging	1.00
R6155:Csmd1	UTSW	8	15,953,231 (GRCm39)	missense	probably benign	0.01
R6197:Csmd1	UTSW	8	15,976,611 (GRCm39)	missense	probably benign	0.32
R6247:Csmd1	UTSW	8	16,246,249 (GRCm39)	missense	possibly damaging	0.91
R6304:Csmd1	UTSW	8	16,108,688 (GRCm39)	missense	probably damaging	1.00
R6317:Csmd1	UTSW	8	16,760,658 (GRCm39)	missense	possibly damaging	0.89
R6318:Csmd1	UTSW	8	15,953,212 (GRCm39)	missense	probably damaging	1.00
R6338:Csmd1	UTSW	8	15,982,492 (GRCm39)	missense	possibly damaging	0.75
R6369:Csmd1	UTSW	8	17,585,020 (GRCm39)	start gained	probably benign
R6447:Csmd1	UTSW	8	15,960,527 (GRCm39)	missense	probably damaging	1.00
R6454:Csmd1	UTSW	8	15,971,150 (GRCm39)	missense	probably damaging	0.99
R6494:Csmd1	UTSW	8	16,261,709 (GRCm39)	splice site	probably null
R6614:Csmd1	UTSW	8	17,266,803 (GRCm39)	missense	probably damaging	1.00
R6736:Csmd1	UTSW	8	16,052,626 (GRCm39)	missense	probably damaging	0.99
R6769:Csmd1	UTSW	8	16,121,408 (GRCm39)	missense	possibly damaging	0.80
R6771:Csmd1	UTSW	8	16,121,408 (GRCm39)	missense	possibly damaging	0.80
R6804:Csmd1	UTSW	8	16,087,260 (GRCm39)	missense	probably damaging	1.00
R6818:Csmd1	UTSW	8	16,235,341 (GRCm39)	missense	probably damaging	1.00
R6863:Csmd1	UTSW	8	17,584,929 (GRCm39)	missense	possibly damaging	0.85
R6930:Csmd1	UTSW	8	16,142,409 (GRCm39)	missense	probably damaging	0.97
R6969:Csmd1	UTSW	8	17,266,805 (GRCm39)	missense	possibly damaging	0.94
R7112:Csmd1	UTSW	8	16,151,142 (GRCm39)	missense	probably damaging	1.00
R7124:Csmd1	UTSW	8	15,953,202 (GRCm39)	missense	probably damaging	1.00
R7167:Csmd1	UTSW	8	15,976,524 (GRCm39)	missense	probably benign
R7243:Csmd1	UTSW	8	15,965,357 (GRCm39)	missense	probably damaging	1.00
R7260:Csmd1	UTSW	8	16,050,574 (GRCm39)	missense	probably damaging	1.00
R7271:Csmd1	UTSW	8	17,077,295 (GRCm39)	missense	probably damaging	0.99
R7324:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7325:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7327:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7373:Csmd1	UTSW	8	16,042,713 (GRCm39)	missense	probably damaging	1.00
R7406:Csmd1	UTSW	8	16,338,707 (GRCm39)	missense	probably damaging	0.99
R7427:Csmd1	UTSW	8	16,073,864 (GRCm39)	missense	possibly damaging	0.91
R7428:Csmd1	UTSW	8	16,073,864 (GRCm39)	missense	possibly damaging	0.91
R7445:Csmd1	UTSW	8	16,208,268 (GRCm39)	missense	possibly damaging	0.61
R7458:Csmd1	UTSW	8	16,003,738 (GRCm39)	missense	probably damaging	1.00
R7476:Csmd1	UTSW	8	15,945,731 (GRCm39)	missense	probably damaging	1.00
R7527:Csmd1	UTSW	8	16,261,732 (GRCm39)	missense	probably damaging	1.00
R7544:Csmd1	UTSW	8	16,142,310 (GRCm39)	missense	probably damaging	1.00
R7583:Csmd1	UTSW	8	16,048,833 (GRCm39)	missense	probably damaging	0.96
R7603:Csmd1	UTSW	8	16,338,696 (GRCm39)	missense	probably damaging	1.00
R7607:Csmd1	UTSW	8	15,968,331 (GRCm39)	missense	possibly damaging	0.94
R7642:Csmd1	UTSW	8	16,135,192 (GRCm39)	missense	probably damaging	0.99
R7669:Csmd1	UTSW	8	15,967,273 (GRCm39)	missense	probably damaging	1.00
R7720:Csmd1	UTSW	8	15,981,108 (GRCm39)	missense	probably damaging	1.00
R7728:Csmd1	UTSW	8	16,281,285 (GRCm39)	missense	probably damaging	1.00
R7738:Csmd1	UTSW	8	16,151,004 (GRCm39)	missense	probably damaging	1.00
R7745:Csmd1	UTSW	8	15,982,461 (GRCm39)	critical splice donor site	probably null
R7879:Csmd1	UTSW	8	16,441,820 (GRCm39)	missense	probably benign	0.28
R7884:Csmd1	UTSW	8	16,011,418 (GRCm39)	missense	probably damaging	1.00
R7897:Csmd1	UTSW	8	17,584,935 (GRCm39)	missense	possibly damaging	0.96
R8111:Csmd1	UTSW	8	15,967,306 (GRCm39)	missense	probably benign
R8119:Csmd1	UTSW	8	17,077,310 (GRCm39)	missense	probably damaging	0.99
R8134:Csmd1	UTSW	8	15,982,550 (GRCm39)	missense	probably damaging	0.99
R8187:Csmd1	UTSW	8	16,177,188 (GRCm39)	missense	probably damaging	0.99
R8196:Csmd1	UTSW	8	16,059,468 (GRCm39)	missense	probably benign	0.18
R8231:Csmd1	UTSW	8	16,747,939 (GRCm39)	missense	possibly damaging	0.82
R8242:Csmd1	UTSW	8	16,760,670 (GRCm39)	missense	probably benign	0.42
R8274:Csmd1	UTSW	8	15,960,453 (GRCm39)	missense	possibly damaging	0.93
R8286:Csmd1	UTSW	8	16,039,188 (GRCm39)	missense	probably benign	0.18
R8289:Csmd1	UTSW	8	16,108,716 (GRCm39)	missense	probably damaging	0.99
R8314:Csmd1	UTSW	8	16,208,258 (GRCm39)	missense	probably benign
R8323:Csmd1	UTSW	8	17,266,751 (GRCm39)	nonsense	probably null
R8387:Csmd1	UTSW	8	16,050,484 (GRCm39)	missense	possibly damaging	0.94
R8413:Csmd1	UTSW	8	15,950,676 (GRCm39)	missense	probably damaging	0.98
R8672:Csmd1	UTSW	8	15,976,598 (GRCm39)	missense	probably benign	0.01
R8765:Csmd1	UTSW	8	16,760,627 (GRCm39)	nonsense	probably null
R8789:Csmd1	UTSW	8	17,266,722 (GRCm39)	missense	probably damaging	0.99
R8828:Csmd1	UTSW	8	16,048,794 (GRCm39)	missense	probably benign	0.00
R8858:Csmd1	UTSW	8	16,120,318 (GRCm39)	missense	probably benign	0.10
R8878:Csmd1	UTSW	8	15,960,528 (GRCm39)	missense	probably damaging	1.00
R8911:Csmd1	UTSW	8	16,748,019 (GRCm39)	missense	probably damaging	0.99
R8966:Csmd1	UTSW	8	16,250,059 (GRCm39)	missense	probably damaging	1.00
R8978:Csmd1	UTSW	8	15,971,056 (GRCm39)	missense	probably benign	0.37
R8996:Csmd1	UTSW	8	15,971,105 (GRCm39)	missense	possibly damaging	0.54
R9045:Csmd1	UTSW	8	16,284,088 (GRCm39)	missense	probably damaging	0.99
R9084:Csmd1	UTSW	8	16,138,325 (GRCm39)	missense	probably benign
R9124:Csmd1	UTSW	8	16,034,806 (GRCm39)	missense	probably damaging	0.99
R9127:Csmd1	UTSW	8	16,273,286 (GRCm39)	missense	probably benign	0.31
R9146:Csmd1	UTSW	8	16,048,832 (GRCm39)	missense	probably benign	0.00
R9198:Csmd1	UTSW	8	15,962,430 (GRCm39)	missense	probably damaging	1.00
R9285:Csmd1	UTSW	8	15,956,088 (GRCm39)	missense	probably damaging	1.00
R9303:Csmd1	UTSW	8	16,011,532 (GRCm39)	missense	probably benign	0.31
R9305:Csmd1	UTSW	8	16,011,532 (GRCm39)	missense	probably benign	0.31
R9326:Csmd1	UTSW	8	16,049,803 (GRCm39)	missense	probably benign	0.21
R9356:Csmd1	UTSW	8	16,252,069 (GRCm39)	missense	probably damaging	1.00
R9385:Csmd1	UTSW	8	16,034,756 (GRCm39)	missense	probably benign	0.19
R9444:Csmd1	UTSW	8	16,208,250 (GRCm39)	missense	probably benign	0.30
R9476:Csmd1	UTSW	8	15,981,215 (GRCm39)	critical splice acceptor site	probably null
R9506:Csmd1	UTSW	8	16,250,023 (GRCm39)	missense	probably damaging	1.00
R9614:Csmd1	UTSW	8	16,208,239 (GRCm39)	missense	probably benign	0.00
R9668:Csmd1	UTSW	8	16,261,772 (GRCm39)	missense	probably benign	0.00
X0011:Csmd1	UTSW	8	16,246,277 (GRCm39)	missense	probably damaging	1.00
X0021:Csmd1	UTSW	8	16,235,270 (GRCm39)	missense	probably damaging	1.00
X0024:Csmd1	UTSW	8	16,087,232 (GRCm39)	missense	probably damaging	0.99
X0028:Csmd1	UTSW	8	15,965,333 (GRCm39)	missense	possibly damaging	0.79
Z1088:Csmd1	UTSW	8	16,239,992 (GRCm39)	missense	possibly damaging	0.50
Z1088:Csmd1	UTSW	8	16,142,272 (GRCm39)	missense	probably damaging	1.00
Z1088:Csmd1	UTSW	8	15,971,875 (GRCm39)	missense	possibly damaging	0.91
Z1088:Csmd1	UTSW	8	16,396,631 (GRCm39)	missense	probably damaging	0.99
Z1088:Csmd1	UTSW	8	16,250,072 (GRCm39)	missense	probably damaging	0.97
Z1176:Csmd1	UTSW	8	16,087,212 (GRCm39)	missense	probably damaging	1.00
Z1176:Csmd1	UTSW	8	16,048,814 (GRCm39)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	16,250,033 (GRCm39)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	16,034,708 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CACCATATGACTGAGACATTTCC -3'
(R):5'- GGGACATTCTTCAAACTATTGCTTG -3'

Sequencing Primer
(F):5'- ATATGACTGAGACATTTCCCCTTTTG -3'
(R):5'- CTTCAAACTATTGCTTGATGATGAC -3'

Posted On

2016-08-04