Incidental Mutation 'R5328:Zfp106'
| ID |
422110 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
042843-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5328 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120506820-120563843 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 120520417 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1584
(N1584K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000152347]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000055241
AA Change: N1607K
PolyPhen 2
Score 0.729 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: N1607K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139942
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152347
|
| SMART Domains |
Protein: ENSMUSP00000132902
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
66 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
163 |
N/A |
INTRINSIC |
|
Pfam:WD40
|
234 |
265 |
1.3e-5 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000171215
AA Change: N1584K
PolyPhen 2
Score 0.729 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: N1584K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb1b |
T |
A |
5: 8,837,694 (GRCm38) |
V860E |
possibly damaging |
Het |
| Abcc6 |
T |
C |
7: 45,992,311 (GRCm38) |
D881G |
probably benign |
Het |
| Abcc9 |
A |
G |
6: 142,682,059 (GRCm38) |
V415A |
probably benign |
Het |
| Adgrb3 |
A |
C |
1: 25,094,275 (GRCm38) |
N1003K |
possibly damaging |
Het |
| Adora3 |
C |
T |
3: 105,907,303 (GRCm38) |
T123I |
probably benign |
Het |
| Amotl2 |
A |
C |
9: 102,723,768 (GRCm38) |
T345P |
probably benign |
Het |
| Arap3 |
C |
T |
18: 37,991,687 (GRCm38) |
E247K |
possibly damaging |
Het |
| Atp8b1 |
A |
T |
18: 64,531,391 (GRCm38) |
D1235E |
probably benign |
Het |
| Axl |
A |
T |
7: 25,773,411 (GRCm38) |
V400E |
probably damaging |
Het |
| Brd8 |
T |
A |
18: 34,607,981 (GRCm38) |
N431Y |
probably benign |
Het |
| Cadps |
A |
T |
14: 12,457,790 (GRCm38) |
N1025K |
probably benign |
Het |
| Cblc |
A |
T |
7: 19,792,580 (GRCm38) |
S195T |
possibly damaging |
Het |
| Chd2 |
C |
T |
7: 73,463,681 (GRCm38) |
A1184T |
possibly damaging |
Het |
| Chst10 |
G |
A |
1: 38,895,962 (GRCm38) |
|
probably benign |
Het |
| Col12a1 |
T |
C |
9: 79,620,060 (GRCm38) |
K2663E |
probably damaging |
Het |
| Cspg4 |
A |
T |
9: 56,885,856 (GRCm38) |
I292L |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,508,317 (GRCm38) |
V294A |
probably damaging |
Het |
| Cyp2d11 |
G |
A |
15: 82,391,771 (GRCm38) |
P203L |
probably benign |
Het |
| Dscam |
T |
C |
16: 96,673,678 (GRCm38) |
H1228R |
probably benign |
Het |
| Eif3l |
A |
T |
15: 79,093,361 (GRCm38) |
K534* |
probably null |
Het |
| Enpep |
T |
C |
3: 129,280,510 (GRCm38) |
E796G |
probably benign |
Het |
| Ext1 |
C |
A |
15: 53,075,817 (GRCm38) |
W612L |
probably damaging |
Het |
| Faap100 |
T |
A |
11: 120,377,632 (GRCm38) |
E105V |
possibly damaging |
Het |
| Fam117a |
T |
A |
11: 95,364,170 (GRCm38) |
|
probably null |
Het |
| Fan1 |
A |
T |
7: 64,354,469 (GRCm38) |
Y750N |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,956,868 (GRCm38) |
I2039N |
probably damaging |
Het |
| Gabrr2 |
G |
T |
4: 33,082,565 (GRCm38) |
D106Y |
probably damaging |
Het |
| Gak |
A |
C |
5: 108,617,001 (GRCm38) |
C145G |
possibly damaging |
Het |
| Galnt14 |
A |
T |
17: 73,505,459 (GRCm38) |
N406K |
possibly damaging |
Het |
| Gm10439 |
T |
G |
X: 149,636,163 (GRCm38) |
*434E |
probably null |
Het |
| Gm10837 |
G |
T |
14: 122,490,778 (GRCm38) |
R22L |
unknown |
Het |
| Gm19965 |
T |
A |
1: 116,821,418 (GRCm38) |
H276Q |
possibly damaging |
Het |
| Gm43517 |
T |
C |
12: 49,391,156 (GRCm38) |
|
probably benign |
Het |
| Gm9733 |
T |
C |
3: 15,332,174 (GRCm38) |
M17V |
unknown |
Het |
| Greb1l |
A |
T |
18: 10,553,720 (GRCm38) |
I1574F |
probably damaging |
Het |
| Gzme |
G |
A |
14: 56,117,767 (GRCm38) |
H236Y |
probably benign |
Het |
| Heatr5b |
G |
A |
17: 78,826,362 (GRCm38) |
T266I |
possibly damaging |
Het |
| Hk3 |
T |
C |
13: 55,013,493 (GRCm38) |
I185V |
probably benign |
Het |
| Hnrnpr |
A |
G |
4: 136,339,216 (GRCm38) |
E302G |
probably benign |
Het |
| Itgal |
T |
C |
7: 127,311,675 (GRCm38) |
|
probably null |
Het |
| Itk |
A |
G |
11: 46,331,876 (GRCm38) |
S583P |
probably benign |
Het |
| Loxhd1 |
A |
T |
18: 77,410,572 (GRCm38) |
I1448F |
probably damaging |
Het |
| Macf1 |
GCCCCC |
GCCCCCC |
4: 123,350,991 (GRCm38) |
|
probably null |
Het |
| Man2a2 |
A |
T |
7: 80,368,756 (GRCm38) |
F118L |
probably benign |
Het |
| Mfsd5 |
T |
A |
15: 102,281,012 (GRCm38) |
V273E |
probably damaging |
Het |
| Nfe2l2 |
A |
G |
2: 75,676,856 (GRCm38) |
L300P |
probably damaging |
Het |
| Nt5c1a |
T |
G |
4: 123,208,993 (GRCm38) |
L122R |
possibly damaging |
Het |
| Nt5c3b |
A |
G |
11: 100,440,241 (GRCm38) |
F42S |
probably damaging |
Het |
| Olfr332 |
C |
A |
11: 58,490,429 (GRCm38) |
A109S |
possibly damaging |
Het |
| Olfr577 |
T |
A |
7: 102,973,968 (GRCm38) |
N8I |
possibly damaging |
Het |
| Pabpc1 |
A |
T |
15: 36,602,877 (GRCm38) |
D204E |
probably benign |
Het |
| Panx2 |
A |
G |
15: 89,068,095 (GRCm38) |
N255S |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,411,719 (GRCm38) |
L993P |
probably damaging |
Het |
| Pfas |
A |
T |
11: 68,988,592 (GRCm38) |
C1160S |
probably damaging |
Het |
| Plekhh3 |
T |
A |
11: 101,167,658 (GRCm38) |
|
probably benign |
Het |
| Plod3 |
T |
A |
5: 136,989,683 (GRCm38) |
N258K |
probably damaging |
Het |
| Prr14l |
T |
C |
5: 32,830,021 (GRCm38) |
Q710R |
probably benign |
Het |
| Rnf216 |
G |
T |
5: 143,092,999 (GRCm38) |
T65K |
possibly damaging |
Het |
| Samd9l |
T |
C |
6: 3,376,739 (GRCm38) |
E174G |
probably damaging |
Het |
| Sept12 |
T |
A |
16: 4,993,993 (GRCm38) |
M63L |
possibly damaging |
Het |
| Sh3bgrl2 |
T |
A |
9: 83,577,456 (GRCm38) |
D22E |
probably benign |
Het |
| Skil |
A |
G |
3: 31,117,569 (GRCm38) |
K488R |
probably benign |
Het |
| Slamf6 |
T |
A |
1: 171,938,095 (GRCm38) |
I262K |
probably benign |
Het |
| Slc27a3 |
T |
C |
3: 90,386,832 (GRCm38) |
D470G |
probably damaging |
Het |
| Sorbs3 |
A |
T |
14: 70,181,174 (GRCm38) |
V680E |
probably damaging |
Het |
| Sox9 |
C |
T |
11: 112,782,658 (GRCm38) |
T25I |
probably benign |
Het |
| Srsf1 |
G |
T |
11: 88,049,993 (GRCm38) |
|
probably benign |
Het |
| Stard9 |
A |
C |
2: 120,699,230 (GRCm38) |
E1989D |
probably damaging |
Het |
| Thumpd2 |
T |
A |
17: 81,044,162 (GRCm38) |
I277F |
possibly damaging |
Het |
| Tinag |
C |
A |
9: 77,005,631 (GRCm38) |
G299* |
probably null |
Het |
| Tk2 |
A |
T |
8: 104,229,299 (GRCm38) |
|
probably null |
Het |
| Tmem44 |
A |
G |
16: 30,540,891 (GRCm38) |
S210P |
possibly damaging |
Het |
| Traf3ip1 |
C |
A |
1: 91,520,069 (GRCm38) |
P423T |
probably damaging |
Het |
| Trmt12 |
A |
G |
15: 58,872,855 (GRCm38) |
D34G |
probably damaging |
Het |
| Ttc39b |
A |
G |
4: 83,261,941 (GRCm38) |
Y72H |
probably damaging |
Het |
| Ttn |
G |
A |
2: 76,878,411 (GRCm38) |
|
probably benign |
Het |
| Ttyh2 |
T |
A |
11: 114,710,068 (GRCm38) |
I381N |
possibly damaging |
Het |
| Uaca |
A |
T |
9: 60,870,532 (GRCm38) |
N734Y |
probably benign |
Het |
| Usp34 |
G |
A |
11: 23,488,659 (GRCm38) |
G3407D |
probably benign |
Het |
| Usp34 |
T |
C |
11: 23,464,616 (GRCm38) |
I2853T |
probably benign |
Het |
| Vmn2r78 |
A |
G |
7: 86,921,030 (GRCm38) |
Y252C |
probably damaging |
Het |
| Wdr19 |
G |
A |
5: 65,244,179 (GRCm38) |
C979Y |
probably damaging |
Het |
| Wdr92 |
C |
A |
11: 17,222,220 (GRCm38) |
P103Q |
probably damaging |
Het |
| Yeats2 |
A |
T |
16: 20,171,205 (GRCm38) |
H277L |
probably damaging |
Het |
| Zbtb2 |
T |
C |
10: 4,369,267 (GRCm38) |
Y253C |
possibly damaging |
Het |
| Zfat |
C |
A |
15: 68,179,828 (GRCm38) |
G706C |
probably damaging |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,539,497 (GRCm38) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,526,848 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,514,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,512,727 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,535,035 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,524,464 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,523,553 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,524,555 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,533,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,534,807 (GRCm38) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,539,322 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,524,043 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,534,231 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,545,914 (GRCm38) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,510,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,531,697 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,528,639 (GRCm38) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,524,024 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,535,387 (GRCm38) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,532,104 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,535,060 (GRCm38) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,533,594 (GRCm38) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,533,677 (GRCm38) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,520,487 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,533,875 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,528,472 (GRCm38) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,532,196 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,527,016 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,555,248 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,535,603 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,534,714 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,520,536 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,520,536 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,524,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,533,594 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,533,677 (GRCm38) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,533,764 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,533,763 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,535,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,520,428 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,513,615 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,526,848 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,531,681 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,523,529 (GRCm38) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,535,650 (GRCm38) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,527,063 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,534,599 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,534,613 (GRCm38) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,532,149 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,533,616 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,534,856 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,526,899 (GRCm38) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,533,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,533,919 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,534,727 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,523,968 (GRCm38) |
missense |
probably benign |
0.11 |
|
R5403:Zfp106
|
UTSW |
2 |
120,534,781 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,531,957 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,533,507 (GRCm38) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,524,471 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,516,006 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,535,393 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,535,393 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,522,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,532,104 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,534,502 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,535,060 (GRCm38) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,539,454 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,531,632 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,545,919 (GRCm38) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,510,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,512,734 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,524,057 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,535,615 (GRCm38) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,514,219 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,524,519 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,524,331 (GRCm38) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,519,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,535,618 (GRCm38) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,535,618 (GRCm38) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,524,119 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,535,596 (GRCm38) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,533,538 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,539,425 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,520,454 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,534,331 (GRCm38) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,522,716 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,520,526 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,519,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,535,326 (GRCm38) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,524,545 (GRCm38) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,524,545 (GRCm38) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,534,816 (GRCm38) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,530,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTACAGCACAAAATCAGCAGATA -3'
(R):5'- ATGTGACTTTGCTTGGCAGTTAG -3'
Sequencing Primer
(F):5'- CAGCACAAAATCAGCAGATAATAATG -3'
(R):5'- CCATCTTGAACCTCAGGAATGGG -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation