Mutagenetix > Incidental Mutation

Incidental Mutation 'R5335:Fcgbp'

423470

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

042916-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5335 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

27770661-27820287 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 27789159 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 575 (V575A)

Ref Sequence

ENSEMBL: ENSMUSP00000114271 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably damaging
Transcript: ENSMUST00000076648
AA Change: V575A

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: V575A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000138392
AA Change: V575A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: V575A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140004

Meta Mutation Damage Score

0.2996

Coding Region Coverage

1x: 99.3%
3x: 98.8%
10x: 97.6%
20x: 96.1%

Validation Efficiency

98% (62/63)

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010003K11Rik	A	G	19: 4,548,292 (GRCm39)	W86R	probably damaging	Het
Ankrd6	T	C	4: 32,818,651 (GRCm39)	E225G	probably damaging	Het
Atxn10	A	G	15: 85,220,785 (GRCm39)		probably null	Het
Bcas2	A	G	3: 103,082,951 (GRCm39)	I146V	probably damaging	Het
C2cd6	T	A	1: 59,043,393 (GRCm39)		noncoding transcript	Het
Cachd1	G	A	4: 100,825,282 (GRCm39)	V579I	possibly damaging	Het
Col11a1	A	G	3: 113,888,889 (GRCm39)	T311A	unknown	Het
Cyp2c50	A	T	19: 40,079,060 (GRCm39)	L134F	probably benign	Het
Cyp2j11	T	C	4: 96,195,589 (GRCm39)	H369R	probably damaging	Het
Dis3	A	G	14: 99,335,089 (GRCm39)	V171A	possibly damaging	Het
Dnah12	A	G	14: 26,601,695 (GRCm39)	N3718D	probably damaging	Het
Dnah17	T	C	11: 118,003,340 (GRCm39)	I541V	probably damaging	Het
Eif3i	T	C	4: 129,488,979 (GRCm39)	D86G	probably benign	Het
Epc1	C	T	18: 6,490,689 (GRCm39)		probably benign	Het
Epc2	A	G	2: 49,403,242 (GRCm39)	N110S	probably benign	Het
Epha8	A	T	4: 136,659,246 (GRCm39)	L831Q	probably damaging	Het
Esd	G	T	14: 74,979,553 (GRCm39)	R119I	probably damaging	Het
F2	T	C	2: 91,465,277 (GRCm39)	K96E	possibly damaging	Het
Gad1-ps	G	A	10: 99,281,009 (GRCm39)		noncoding transcript	Het
Gemin6	T	C	17: 80,533,184 (GRCm39)	V39A	probably damaging	Het
Glmp	G	T	3: 88,233,962 (GRCm39)		probably benign	Het
Gm10306	C	A	4: 94,445,044 (GRCm39)		probably benign	Het
Gm4846	A	T	1: 166,325,022 (GRCm39)	L23*	probably null	Het
Grik1	CGG	CGGG	16: 87,720,082 (GRCm39)		probably null	Het
Ifi203	T	C	1: 173,754,485 (GRCm39)	T749A	possibly damaging	Het
Kcnip2	C	A	19: 45,782,685 (GRCm39)	A133S	probably benign	Het
Limch1	A	T	5: 67,039,300 (GRCm39)	I76F	probably damaging	Het
Mcph1	T	A	8: 18,739,077 (GRCm39)		probably null	Het
Mplkipl1	C	T	19: 61,164,364 (GRCm39)	G24R	unknown	Het
Mtcl3	A	T	10: 29,023,102 (GRCm39)	I150L	probably benign	Het
Myh7	A	G	14: 55,224,020 (GRCm39)		probably benign	Het
Odad2	A	T	18: 7,294,566 (GRCm39)	Y16N	probably benign	Het
Opcml	A	G	9: 28,586,621 (GRCm39)	D113G	possibly damaging	Het
Or1j17	A	T	2: 36,578,106 (GRCm39)	I31F	probably benign	Het
Or1x2	A	C	11: 50,918,161 (GRCm39)	N111H	probably benign	Het
Or2ag18	A	C	7: 106,404,941 (GRCm39)	S243A	probably damaging	Het
Or2b6	A	C	13: 21,822,949 (GRCm39)	V248G	probably damaging	Het
Or51f1d	A	C	7: 102,700,742 (GRCm39)	D79A	probably damaging	Het
Or52s19	A	C	7: 103,007,729 (GRCm39)	L224R	probably damaging	Het
Or5j1	T	G	2: 86,879,509 (GRCm39)	K24Q	probably damaging	Het
Pcdhb1	G	T	18: 37,400,308 (GRCm39)	C753F	probably benign	Het
Phip	T	C	9: 82,782,809 (GRCm39)	S879G	possibly damaging	Het
Pi4k2b	A	G	5: 52,899,098 (GRCm39)	D13G	possibly damaging	Het
Ptpn18	A	T	1: 34,502,259 (GRCm39)	I68F	probably damaging	Het
Rnf168	C	T	16: 32,117,402 (GRCm39)	T321I	possibly damaging	Het
Sp110	C	G	1: 85,516,839 (GRCm39)	E219D	probably damaging	Het
Srgap1	C	T	10: 121,621,282 (GRCm39)		probably benign	Het
Sry	A	T	Y: 2,663,647 (GRCm39)	H4Q	probably benign	Het
Taf2	G	A	15: 54,909,136 (GRCm39)	A703V	probably benign	Het
Taf5l	A	G	8: 124,730,390 (GRCm39)	F65L	probably damaging	Het
Tcp10b	T	C	17: 13,281,954 (GRCm39)		probably null	Het
Timm44	A	T	8: 4,316,814 (GRCm39)	I273N	probably damaging	Het
Tspan4	A	G	7: 141,069,528 (GRCm39)	T43A	probably damaging	Het
Ube2r2	T	C	4: 41,190,846 (GRCm39)		probably benign	Het
Urgcp	T	C	11: 5,667,754 (GRCm39)	T195A	possibly damaging	Het
Vmn1r197	T	C	13: 22,512,361 (GRCm39)	I94T	probably damaging	Het
Vmn2r15	A	T	5: 109,434,673 (GRCm39)	I677K	probably damaging	Het
Zfp853	T	A	5: 143,274,318 (GRCm39)	H434L	unknown	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	27,784,555 (GRCm39)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	27,800,966 (GRCm39)	splice site	probably benign
IGL00335:Fcgbp	APN	7	27,785,560 (GRCm39)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	27,774,511 (GRCm39)	nonsense	probably null
IGL00491:Fcgbp	APN	7	27,792,827 (GRCm39)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	27,791,222 (GRCm39)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	27,789,072 (GRCm39)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	27,793,067 (GRCm39)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	27,803,388 (GRCm39)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	27,805,799 (GRCm39)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	27,774,629 (GRCm39)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	27,791,379 (GRCm39)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	27,774,660 (GRCm39)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	27,771,068 (GRCm39)	splice site	probably benign
IGL02377:Fcgbp	APN	7	27,806,395 (GRCm39)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	27,774,596 (GRCm39)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	27,789,378 (GRCm39)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	27,804,157 (GRCm39)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	27,800,599 (GRCm39)	intron	probably benign
IGL02631:Fcgbp	APN	7	27,784,723 (GRCm39)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	27,800,859 (GRCm39)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	27,816,783 (GRCm39)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	27,791,272 (GRCm39)	nonsense	probably null
IGL02971:Fcgbp	APN	7	27,800,898 (GRCm39)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	27,784,857 (GRCm39)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	27,789,342 (GRCm39)	missense	possibly damaging	0.76
bilge	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
swill	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	27,800,576 (GRCm39)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	27,774,698 (GRCm39)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	27,784,918 (GRCm39)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	27,790,879 (GRCm39)	splice site	probably benign
R0586:Fcgbp	UTSW	7	27,789,138 (GRCm39)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	27,784,535 (GRCm39)	nonsense	probably null
R0987:Fcgbp	UTSW	7	27,793,599 (GRCm39)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	27,819,950 (GRCm39)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	27,803,158 (GRCm39)	nonsense	probably null
R1474:Fcgbp	UTSW	7	27,791,273 (GRCm39)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	27,774,585 (GRCm39)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	27,800,674 (GRCm39)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	27,792,868 (GRCm39)	nonsense	probably null
R1772:Fcgbp	UTSW	7	27,804,600 (GRCm39)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	27,785,564 (GRCm39)	missense	probably benign
R1808:Fcgbp	UTSW	7	27,784,515 (GRCm39)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	27,784,708 (GRCm39)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	27,806,518 (GRCm39)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	27,793,617 (GRCm39)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	27,819,785 (GRCm39)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	27,791,444 (GRCm39)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	27,806,628 (GRCm39)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	27,774,838 (GRCm39)	splice site	probably benign
R3037:Fcgbp	UTSW	7	27,802,127 (GRCm39)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	27,816,665 (GRCm39)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	27,800,701 (GRCm39)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	27,784,882 (GRCm39)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	27,806,721 (GRCm39)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	27,794,362 (GRCm39)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	27,813,383 (GRCm39)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	27,785,660 (GRCm39)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	27,789,237 (GRCm39)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	27,816,995 (GRCm39)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	27,785,528 (GRCm39)	splice site	probably null
R5219:Fcgbp	UTSW	7	27,803,510 (GRCm39)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	27,784,624 (GRCm39)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	27,793,099 (GRCm39)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	27,791,243 (GRCm39)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	27,804,480 (GRCm39)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	27,784,738 (GRCm39)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	27,793,060 (GRCm39)	missense	probably benign
R5583:Fcgbp	UTSW	7	27,791,004 (GRCm39)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	27,791,447 (GRCm39)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	27,784,643 (GRCm39)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	27,800,919 (GRCm39)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	27,784,928 (GRCm39)	splice site	probably benign
R5936:Fcgbp	UTSW	7	27,786,117 (GRCm39)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	27,819,959 (GRCm39)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	27,804,390 (GRCm39)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	27,806,433 (GRCm39)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	27,792,963 (GRCm39)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	27,785,695 (GRCm39)	nonsense	probably null
R6711:Fcgbp	UTSW	7	27,789,098 (GRCm39)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	27,802,637 (GRCm39)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	27,784,443 (GRCm39)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	27,789,129 (GRCm39)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	27,793,248 (GRCm39)	missense	probably benign
R6943:Fcgbp	UTSW	7	27,791,477 (GRCm39)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	27,791,358 (GRCm39)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	27,784,387 (GRCm39)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	27,803,446 (GRCm39)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	27,800,817 (GRCm39)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	27,792,861 (GRCm39)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	27,800,932 (GRCm39)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	27,785,949 (GRCm39)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	27,806,710 (GRCm39)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	27,802,401 (GRCm39)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	27,789,099 (GRCm39)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	27,784,794 (GRCm39)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	27,785,724 (GRCm39)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	27,802,391 (GRCm39)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	27,790,928 (GRCm39)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	27,784,460 (GRCm39)	nonsense	probably null
R7820:Fcgbp	UTSW	7	27,819,784 (GRCm39)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	27,806,404 (GRCm39)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	27,816,632 (GRCm39)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	27,803,595 (GRCm39)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	27,813,389 (GRCm39)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	27,804,496 (GRCm39)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	27,784,507 (GRCm39)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	27,784,919 (GRCm39)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	27,791,174 (GRCm39)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	27,804,276 (GRCm39)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	27,793,614 (GRCm39)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	27,806,815 (GRCm39)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	27,789,231 (GRCm39)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	27,804,435 (GRCm39)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	27,785,978 (GRCm39)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	27,819,920 (GRCm39)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	27,805,621 (GRCm39)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	27,784,412 (GRCm39)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	27,785,934 (GRCm39)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	27,790,908 (GRCm39)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	27,791,277 (GRCm39)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	27,803,198 (GRCm39)	nonsense	probably null
R9262:Fcgbp	UTSW	7	27,819,952 (GRCm39)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	27,803,436 (GRCm39)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	27,790,937 (GRCm39)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	27,802,563 (GRCm39)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	27,800,832 (GRCm39)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	27,806,400 (GRCm39)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	27,793,000 (GRCm39)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	27,803,012 (GRCm39)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
X0028:Fcgbp	UTSW	7	27,803,445 (GRCm39)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	27,791,072 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,785,616 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,803,309 (GRCm39)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	27,792,770 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCCAGCTGAGTGAAAACACG -3'
(R):5'- GGTCACAAGGGAGTCCAATTG -3'

Sequencing Primer
(F):5'- GAAAACCCTGACTGACCTGTTG -3'
(R):5'- TCCAATTGGGGACAGTCACC -3'

Posted On

2016-08-04