Incidental Mutation 'R5386:Golgb1'
| ID |
425288 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Golgb1
|
| Ensembl Gene |
ENSMUSG00000034243 |
| Gene Name |
golgi autoantigen, golgin subfamily b, macrogolgin 1 |
| Synonyms |
Giantin, C130074L01Rik, F730017E11Rik, Gm6840, 6330407A06Rik |
| Accession Numbers |
Genbank: NM_030035.1
|
| Essential gene? |
Probably essential
(E-score: 0.911)
|
| Stock # |
R5386 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
36875140-36933085 bp(+) (GRCm38) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 36912315 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 641
(C641*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039855]
[ENSMUST00000114812]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039855
AA Change: C682*
|
| SMART Domains |
Protein: ENSMUSP00000045239
Gene: ENSMUSG00000034243
AA Change: C682*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
24 |
61 |
7.47e-6 |
PROSPERO |
|
low complexity region
|
87 |
107 |
N/A |
INTRINSIC |
|
coiled coil region
|
130 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
512 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
519 |
558 |
7.47e-6 |
PROSPERO |
|
coiled coil region
|
563 |
594 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
627 |
661 |
3.38e-5 |
PROSPERO |
|
coiled coil region
|
679 |
1121 |
N/A |
INTRINSIC |
|
coiled coil region
|
1153 |
1240 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1253 |
1288 |
3.38e-5 |
PROSPERO |
|
low complexity region
|
1300 |
1314 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1321 |
1352 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
1357 |
1369 |
N/A |
INTRINSIC |
|
coiled coil region
|
1402 |
1755 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1760 |
1798 |
7.47e-6 |
PROSPERO |
|
internal_repeat_3
|
1761 |
1804 |
7.47e-6 |
PROSPERO |
|
coiled coil region
|
1818 |
2034 |
N/A |
INTRINSIC |
|
low complexity region
|
2291 |
2306 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
2351 |
2382 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
2400 |
2418 |
N/A |
INTRINSIC |
|
low complexity region
|
2538 |
2549 |
N/A |
INTRINSIC |
|
coiled coil region
|
2775 |
2827 |
N/A |
INTRINSIC |
|
coiled coil region
|
2854 |
2943 |
N/A |
INTRINSIC |
|
low complexity region
|
2964 |
2976 |
N/A |
INTRINSIC |
|
coiled coil region
|
3007 |
3057 |
N/A |
INTRINSIC |
|
coiled coil region
|
3117 |
3163 |
N/A |
INTRINSIC |
|
transmembrane domain
|
3215 |
3237 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000114812
AA Change: C641*
|
| SMART Domains |
Protein: ENSMUSP00000110460
Gene: ENSMUSG00000034243
AA Change: C641*
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
24 |
61 |
6.71e-6 |
PROSPERO |
|
low complexity region
|
87 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
120 |
134 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
154 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
450 |
471 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
478 |
517 |
6.71e-6 |
PROSPERO |
|
coiled coil region
|
522 |
553 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
586 |
620 |
3.05e-5 |
PROSPERO |
|
coiled coil region
|
638 |
1080 |
N/A |
INTRINSIC |
|
coiled coil region
|
1112 |
1199 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1212 |
1247 |
3.05e-5 |
PROSPERO |
|
low complexity region
|
1259 |
1273 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1280 |
1311 |
3.14e-6 |
PROSPERO |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
coiled coil region
|
1361 |
1714 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1719 |
1757 |
6.71e-6 |
PROSPERO |
|
internal_repeat_3
|
1720 |
1763 |
6.71e-6 |
PROSPERO |
|
coiled coil region
|
1777 |
1993 |
N/A |
INTRINSIC |
|
low complexity region
|
2250 |
2265 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
2310 |
2341 |
3.14e-6 |
PROSPERO |
|
low complexity region
|
2359 |
2377 |
N/A |
INTRINSIC |
|
low complexity region
|
2497 |
2508 |
N/A |
INTRINSIC |
|
coiled coil region
|
2734 |
2786 |
N/A |
INTRINSIC |
|
coiled coil region
|
2813 |
2902 |
N/A |
INTRINSIC |
|
low complexity region
|
2923 |
2935 |
N/A |
INTRINSIC |
|
coiled coil region
|
2966 |
3016 |
N/A |
INTRINSIC |
|
coiled coil region
|
3076 |
3122 |
N/A |
INTRINSIC |
|
transmembrane domain
|
3174 |
3196 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous knockout affects glycosylation of glycoproteins in the extra-cellular matrix of the palatal shelves, resulting in their failure to elevate and fuse, leading to cleft palate. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, other(2) Gene trapped(5)
|
| Other mutations in this stock |
Total: 134 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410089E03Rik |
G |
A |
15: 8,194,413 (GRCm38) |
G887R |
probably damaging |
Het |
| 4931406P16Rik |
A |
G |
7: 34,242,388 (GRCm38) |
F120L |
probably damaging |
Het |
| Abcc12 |
T |
G |
8: 86,517,489 (GRCm38) |
K1012Q |
possibly damaging |
Het |
| Afmid |
G |
A |
11: 117,828,142 (GRCm38) |
G33R |
probably benign |
Het |
| Agbl3 |
G |
T |
6: 34,799,196 (GRCm38) |
W207C |
probably damaging |
Het |
| Ajuba |
T |
C |
14: 54,570,398 (GRCm38) |
Y459C |
probably damaging |
Het |
| Ak2 |
T |
C |
4: 129,008,172 (GRCm38) |
S213P |
probably benign |
Het |
| Alk |
T |
A |
17: 71,875,012 (GRCm38) |
N1339Y |
probably damaging |
Het |
| Angpt1 |
T |
C |
15: 42,438,365 (GRCm38) |
S416G |
probably damaging |
Het |
| Ank2 |
C |
T |
3: 126,981,933 (GRCm38) |
V854M |
probably benign |
Het |
| Ankrd61 |
G |
T |
5: 143,891,664 (GRCm38) |
N122K |
possibly damaging |
Het |
| Armc9 |
T |
A |
1: 86,198,289 (GRCm38) |
L34Q |
probably null |
Het |
| Aspg |
T |
A |
12: 112,123,032 (GRCm38) |
V418E |
probably benign |
Het |
| Baz1b |
C |
T |
5: 135,238,059 (GRCm38) |
R1241C |
probably damaging |
Het |
| Bclaf1 |
T |
C |
10: 20,325,592 (GRCm38) |
V201A |
possibly damaging |
Het |
| C1ql3 |
A |
T |
2: 13,004,358 (GRCm38) |
D225E |
probably damaging |
Het |
| Capn9 |
A |
G |
8: 124,605,540 (GRCm38) |
T417A |
possibly damaging |
Het |
| Card14 |
C |
T |
11: 119,317,289 (GRCm38) |
R62C |
probably damaging |
Het |
| Cc2d2a |
A |
G |
5: 43,730,041 (GRCm38) |
N1271S |
probably benign |
Het |
| Ccpg1 |
G |
A |
9: 73,013,044 (GRCm38) |
S647N |
probably benign |
Het |
| Cdv3 |
T |
C |
9: 103,355,230 (GRCm38) |
K133R |
possibly damaging |
Het |
| Cep128 |
A |
C |
12: 90,999,571 (GRCm38) |
S1087R |
probably benign |
Het |
| Cep70 |
T |
A |
9: 99,281,075 (GRCm38) |
L325Q |
probably damaging |
Het |
| Chit1 |
T |
G |
1: 134,149,454 (GRCm38) |
F332V |
probably damaging |
Het |
| Chodl |
C |
A |
16: 78,946,697 (GRCm38) |
T219K |
probably damaging |
Het |
| Cntn4 |
T |
C |
6: 106,181,804 (GRCm38) |
L10P |
possibly damaging |
Het |
| Copg1 |
G |
T |
6: 87,890,207 (GRCm38) |
M87I |
possibly damaging |
Het |
| Cyp3a59 |
A |
G |
5: 146,085,768 (GRCm38) |
Y28C |
probably benign |
Het |
| Dchs1 |
A |
C |
7: 105,758,029 (GRCm38) |
V2119G |
probably damaging |
Het |
| Dedd |
T |
C |
1: 171,338,383 (GRCm38) |
L23P |
probably damaging |
Het |
| Dmxl2 |
A |
G |
9: 54,378,757 (GRCm38) |
S2715P |
probably benign |
Het |
| Dnah9 |
T |
C |
11: 66,029,356 (GRCm38) |
N2237S |
probably damaging |
Het |
| Drosha |
A |
G |
15: 12,842,121 (GRCm38) |
I337V |
probably benign |
Het |
| Duox2 |
A |
G |
2: 122,295,136 (GRCm38) |
V330A |
probably benign |
Het |
| Dusp11 |
T |
C |
6: 85,947,605 (GRCm38) |
*322W |
probably null |
Het |
| Dusp8 |
T |
A |
7: 142,089,993 (GRCm38) |
Q61L |
possibly damaging |
Het |
| Ears2 |
G |
C |
7: 122,044,377 (GRCm38) |
T426S |
probably benign |
Het |
| Elmo1 |
T |
C |
13: 20,600,210 (GRCm38) |
Y646H |
probably benign |
Het |
| Eps15 |
T |
A |
4: 109,321,225 (GRCm38) |
I220K |
possibly damaging |
Het |
| Faap100 |
T |
A |
11: 120,377,632 (GRCm38) |
E105V |
possibly damaging |
Het |
| Fam171a2 |
C |
A |
11: 102,437,867 (GRCm38) |
V689L |
possibly damaging |
Het |
| Fam213b |
T |
A |
4: 154,899,005 (GRCm38) |
M1L |
probably benign |
Het |
| Fam91a1 |
G |
A |
15: 58,448,394 (GRCm38) |
S645N |
probably benign |
Het |
| Fancg |
G |
A |
4: 43,007,076 (GRCm38) |
Q234* |
probably null |
Het |
| Gid4 |
T |
A |
11: 60,432,442 (GRCm38) |
|
probably null |
Het |
| Gm14085 |
C |
A |
2: 122,522,778 (GRCm38) |
L480I |
probably benign |
Het |
| Gm7361 |
A |
C |
5: 26,258,905 (GRCm38) |
T53P |
probably benign |
Het |
| Gon4l |
T |
A |
3: 88,858,496 (GRCm38) |
M409K |
probably benign |
Het |
| Gpatch8 |
A |
T |
11: 102,508,227 (GRCm38) |
|
probably null |
Het |
| Gpr156 |
T |
A |
16: 37,948,309 (GRCm38) |
V64E |
possibly damaging |
Het |
| Grid2 |
T |
A |
6: 63,931,105 (GRCm38) |
I243K |
probably damaging |
Het |
| Gucy2g |
G |
A |
19: 55,215,116 (GRCm38) |
A750V |
probably damaging |
Het |
| Hdac5 |
T |
C |
11: 102,202,141 (GRCm38) |
E590G |
possibly damaging |
Het |
| Herc3 |
T |
A |
6: 58,874,278 (GRCm38) |
M504K |
probably damaging |
Het |
| Hif1a |
A |
G |
12: 73,944,093 (GRCm38) |
E713G |
probably benign |
Het |
| Hmx3 |
A |
G |
7: 131,544,304 (GRCm38) |
D247G |
probably damaging |
Het |
| Hoxd11 |
G |
T |
2: 74,682,819 (GRCm38) |
E143* |
probably null |
Het |
| Ifitm3 |
T |
C |
7: 141,010,641 (GRCm38) |
N2S |
probably benign |
Het |
| Il17f |
T |
C |
1: 20,777,957 (GRCm38) |
Q99R |
probably benign |
Het |
| Itga6 |
T |
A |
2: 71,841,150 (GRCm38) |
S341R |
probably damaging |
Het |
| Itgam |
A |
G |
7: 128,107,980 (GRCm38) |
N661S |
probably benign |
Het |
| Jag1 |
A |
T |
2: 137,095,544 (GRCm38) |
H303Q |
possibly damaging |
Het |
| Kcnh8 |
T |
A |
17: 52,725,995 (GRCm38) |
N103K |
probably benign |
Het |
| Kdm6b |
T |
C |
11: 69,400,810 (GRCm38) |
|
probably benign |
Het |
| Keg1 |
A |
C |
19: 12,714,538 (GRCm38) |
N63T |
probably damaging |
Het |
| Klf12 |
T |
A |
14: 99,900,159 (GRCm38) |
H317L |
probably damaging |
Het |
| Lrp1 |
A |
T |
10: 127,592,114 (GRCm38) |
V530E |
probably damaging |
Het |
| Mrgpra6 |
A |
G |
7: 47,188,881 (GRCm38) |
C190R |
probably damaging |
Het |
| Myo1a |
G |
T |
10: 127,705,897 (GRCm38) |
E102* |
probably null |
Het |
| Napa |
A |
T |
7: 16,116,472 (GRCm38) |
E265D |
probably benign |
Het |
| Ncam1 |
A |
C |
9: 49,564,874 (GRCm38) |
V305G |
probably damaging |
Het |
| Nek8 |
T |
C |
11: 78,170,437 (GRCm38) |
|
probably null |
Het |
| Olfr1115 |
C |
T |
2: 87,252,483 (GRCm38) |
P182L |
probably benign |
Het |
| Olfr1242 |
G |
T |
2: 89,494,137 (GRCm38) |
Y58* |
probably null |
Het |
| Olfr1275 |
T |
C |
2: 111,231,194 (GRCm38) |
T200A |
probably benign |
Het |
| Olfr191 |
T |
A |
16: 59,085,890 (GRCm38) |
M198L |
probably benign |
Het |
| Olfr243 |
T |
C |
7: 103,717,355 (GRCm38) |
F254L |
probably benign |
Het |
| Olfr251 |
A |
T |
9: 38,377,985 (GRCm38) |
I29F |
probably benign |
Het |
| Olfr739 |
T |
A |
14: 50,425,389 (GRCm38) |
V290E |
possibly damaging |
Het |
| Olfr971 |
A |
G |
9: 39,839,830 (GRCm38) |
Y132C |
possibly damaging |
Het |
| Olfr987 |
T |
C |
2: 85,331,635 (GRCm38) |
T88A |
probably benign |
Het |
| Pabpc4 |
A |
G |
4: 123,294,997 (GRCm38) |
Q417R |
probably benign |
Het |
| Panx3 |
A |
T |
9: 37,669,024 (GRCm38) |
M11K |
probably damaging |
Het |
| Pcbp1 |
C |
T |
6: 86,525,489 (GRCm38) |
E143K |
probably damaging |
Het |
| Pdcd7 |
G |
A |
9: 65,358,692 (GRCm38) |
W477* |
probably null |
Het |
| Pi4k2a |
G |
A |
19: 42,090,515 (GRCm38) |
S5N |
probably damaging |
Het |
| Plag1 |
T |
A |
4: 3,904,075 (GRCm38) |
Q372L |
probably benign |
Het |
| Plce1 |
C |
A |
19: 38,760,091 (GRCm38) |
N1755K |
probably damaging |
Het |
| Pld4 |
G |
T |
12: 112,763,988 (GRCm38) |
E102* |
probably null |
Het |
| Pnlip |
A |
G |
19: 58,679,607 (GRCm38) |
N345S |
probably benign |
Het |
| Ppm1e |
A |
T |
11: 87,358,551 (GRCm38) |
L118Q |
possibly damaging |
Het |
| Prkra |
T |
G |
2: 76,639,278 (GRCm38) |
T146P |
probably damaging |
Het |
| Prpf8 |
A |
G |
11: 75,495,799 (GRCm38) |
D1038G |
probably damaging |
Het |
| Prss51 |
T |
A |
14: 64,097,094 (GRCm38) |
V108E |
probably damaging |
Het |
| Ptch1 |
A |
G |
13: 63,545,043 (GRCm38) |
Y181H |
probably damaging |
Het |
| Reln |
A |
G |
5: 22,039,529 (GRCm38) |
V817A |
probably benign |
Het |
| Rictor |
C |
A |
15: 6,789,504 (GRCm38) |
Q1403K |
probably benign |
Het |
| Rims1 |
T |
A |
1: 22,412,245 (GRCm38) |
I882F |
probably damaging |
Het |
| Rnf19a |
A |
G |
15: 36,242,039 (GRCm38) |
V618A |
probably benign |
Het |
| Ryr1 |
A |
T |
7: 29,117,416 (GRCm38) |
I65N |
probably damaging |
Het |
| S1pr2 |
T |
C |
9: 20,967,594 (GRCm38) |
T313A |
probably benign |
Het |
| Serpine2 |
A |
T |
1: 79,821,287 (GRCm38) |
Y83* |
probably null |
Het |
| Sfi1 |
A |
ATCTTCCCAAAGCCAGTGC |
11: 3,153,384 (GRCm38) |
|
probably benign |
Het |
| Sgip1 |
T |
C |
4: 102,915,059 (GRCm38) |
V215A |
probably benign |
Het |
| Sgsm3 |
T |
C |
15: 81,007,999 (GRCm38) |
V256A |
probably benign |
Het |
| Shroom4 |
T |
A |
X: 6,585,469 (GRCm38) |
C894* |
probably null |
Het |
| Slc14a2 |
T |
A |
18: 78,185,840 (GRCm38) |
D306V |
possibly damaging |
Het |
| Slc4a10 |
A |
T |
2: 62,290,058 (GRCm38) |
E843V |
probably damaging |
Het |
| Smyd4 |
T |
A |
11: 75,390,156 (GRCm38) |
C152S |
probably damaging |
Het |
| Snx10 |
T |
C |
6: 51,575,972 (GRCm38) |
Y32H |
probably damaging |
Het |
| Sorl1 |
T |
C |
9: 42,057,284 (GRCm38) |
T558A |
possibly damaging |
Het |
| Spata31d1b |
G |
A |
13: 59,719,052 (GRCm38) |
C1338Y |
possibly damaging |
Het |
| Sppl2c |
T |
A |
11: 104,187,301 (GRCm38) |
I309K |
possibly damaging |
Het |
| Stard9 |
A |
G |
2: 120,700,630 (GRCm38) |
E2456G |
probably damaging |
Het |
| Stx1b |
A |
T |
7: 127,815,403 (GRCm38) |
D16E |
probably benign |
Het |
| Tecpr2 |
T |
C |
12: 110,915,453 (GRCm38) |
V152A |
probably damaging |
Het |
| Tedc1 |
T |
C |
12: 113,156,682 (GRCm38) |
V47A |
probably benign |
Het |
| Tep1 |
A |
T |
14: 50,868,317 (GRCm38) |
L82Q |
probably damaging |
Het |
| Tgm4 |
A |
G |
9: 123,056,494 (GRCm38) |
Y367C |
probably damaging |
Het |
| Tle1 |
C |
T |
4: 72,141,844 (GRCm38) |
V258M |
probably damaging |
Het |
| Tm9sf1 |
C |
T |
14: 55,642,844 (GRCm38) |
G32D |
possibly damaging |
Het |
| Tmco2 |
A |
G |
4: 121,105,984 (GRCm38) |
L106P |
probably damaging |
Het |
| Tmem131 |
A |
T |
1: 36,872,558 (GRCm38) |
C103S |
possibly damaging |
Het |
| Tmprss7 |
T |
A |
16: 45,669,528 (GRCm38) |
I444F |
possibly damaging |
Het |
| Trank1 |
T |
C |
9: 111,362,402 (GRCm38) |
V493A |
probably benign |
Het |
| Trim80 |
A |
T |
11: 115,448,017 (GRCm38) |
T558S |
probably benign |
Het |
| Trmt6 |
C |
A |
2: 132,808,783 (GRCm38) |
A302S |
probably benign |
Het |
| Ttc17 |
A |
T |
2: 94,303,640 (GRCm38) |
W1067R |
probably damaging |
Het |
| Tulp4 |
T |
A |
17: 6,236,293 (GRCm38) |
V1532D |
probably damaging |
Het |
| Ubqlnl |
T |
G |
7: 104,149,217 (GRCm38) |
I358L |
probably benign |
Het |
| Ulk3 |
T |
A |
9: 57,590,740 (GRCm38) |
I108N |
possibly damaging |
Het |
| Vps13b |
A |
T |
15: 35,640,528 (GRCm38) |
|
probably null |
Het |
| Vwa3a |
A |
G |
7: 120,790,142 (GRCm38) |
K68E |
possibly damaging |
Het |
| Zfp746 |
G |
T |
6: 48,064,176 (GRCm38) |
H538N |
possibly damaging |
Het |
|
| Other mutations in Golgb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01394:Golgb1
|
APN |
16 |
36,931,564 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01717:Golgb1
|
APN |
16 |
36,915,502 (GRCm38) |
nonsense |
probably null |
|
|
IGL01965:Golgb1
|
APN |
16 |
36,917,920 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02128:Golgb1
|
APN |
16 |
36,916,304 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02268:Golgb1
|
APN |
16 |
36,913,128 (GRCm38) |
missense |
probably benign |
0.25 |
|
IGL02383:Golgb1
|
APN |
16 |
36,886,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02444:Golgb1
|
APN |
16 |
36,907,816 (GRCm38) |
splice site |
probably benign |
|
|
IGL02635:Golgb1
|
APN |
16 |
36,915,013 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02655:Golgb1
|
APN |
16 |
36,918,080 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02887:Golgb1
|
APN |
16 |
36,925,849 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02937:Golgb1
|
APN |
16 |
36,916,210 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02973:Golgb1
|
APN |
16 |
36,912,080 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02982:Golgb1
|
APN |
16 |
36,925,810 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03065:Golgb1
|
APN |
16 |
36,912,866 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL03109:Golgb1
|
APN |
16 |
36,915,611 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03323:Golgb1
|
APN |
16 |
36,913,453 (GRCm38) |
nonsense |
probably null |
|
|
I2288:Golgb1
|
UTSW |
16 |
36,898,542 (GRCm38) |
missense |
probably benign |
0.00 |
|
I2289:Golgb1
|
UTSW |
16 |
36,898,542 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0071:Golgb1
|
UTSW |
16 |
36,915,503 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0071:Golgb1
|
UTSW |
16 |
36,915,503 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0080:Golgb1
|
UTSW |
16 |
36,898,611 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0102:Golgb1
|
UTSW |
16 |
36,875,468 (GRCm38) |
intron |
probably benign |
|
|
R0242:Golgb1
|
UTSW |
16 |
36,875,630 (GRCm38) |
nonsense |
probably null |
|
|
R0242:Golgb1
|
UTSW |
16 |
36,875,630 (GRCm38) |
nonsense |
probably null |
|
|
R0276:Golgb1
|
UTSW |
16 |
36,913,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0394:Golgb1
|
UTSW |
16 |
36,875,579 (GRCm38) |
intron |
probably benign |
|
|
R0469:Golgb1
|
UTSW |
16 |
36,931,635 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0522:Golgb1
|
UTSW |
16 |
36,915,205 (GRCm38) |
frame shift |
probably null |
|
|
R0575:Golgb1
|
UTSW |
16 |
36,918,809 (GRCm38) |
missense |
probably benign |
|
|
R0600:Golgb1
|
UTSW |
16 |
36,916,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0608:Golgb1
|
UTSW |
16 |
36,916,330 (GRCm38) |
nonsense |
probably null |
|
|
R0711:Golgb1
|
UTSW |
16 |
36,918,790 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0785:Golgb1
|
UTSW |
16 |
36,898,790 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R0893:Golgb1
|
UTSW |
16 |
36,912,277 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R1163:Golgb1
|
UTSW |
16 |
36,916,126 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R1208:Golgb1
|
UTSW |
16 |
36,915,205 (GRCm38) |
frame shift |
probably null |
|
|
R1315:Golgb1
|
UTSW |
16 |
36,914,900 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1429:Golgb1
|
UTSW |
16 |
36,900,563 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1505:Golgb1
|
UTSW |
16 |
36,919,643 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R1537:Golgb1
|
UTSW |
16 |
36,898,788 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R1610:Golgb1
|
UTSW |
16 |
36,926,101 (GRCm38) |
missense |
probably benign |
0.25 |
|
R1659:Golgb1
|
UTSW |
16 |
36,887,617 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1769:Golgb1
|
UTSW |
16 |
36,916,001 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2105:Golgb1
|
UTSW |
16 |
36,914,664 (GRCm38) |
missense |
probably benign |
|
|
R2212:Golgb1
|
UTSW |
16 |
36,887,347 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2261:Golgb1
|
UTSW |
16 |
36,893,360 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2352:Golgb1
|
UTSW |
16 |
36,898,559 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2357:Golgb1
|
UTSW |
16 |
36,912,008 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2400:Golgb1
|
UTSW |
16 |
36,918,466 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R2513:Golgb1
|
UTSW |
16 |
36,915,151 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R3103:Golgb1
|
UTSW |
16 |
36,894,849 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3413:Golgb1
|
UTSW |
16 |
36,887,347 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3748:Golgb1
|
UTSW |
16 |
36,918,912 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3847:Golgb1
|
UTSW |
16 |
36,898,733 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3850:Golgb1
|
UTSW |
16 |
36,898,733 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3936:Golgb1
|
UTSW |
16 |
36,914,056 (GRCm38) |
nonsense |
probably null |
|
|
R3975:Golgb1
|
UTSW |
16 |
36,918,571 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4025:Golgb1
|
UTSW |
16 |
36,915,344 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4369:Golgb1
|
UTSW |
16 |
36,916,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4518:Golgb1
|
UTSW |
16 |
36,929,263 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4600:Golgb1
|
UTSW |
16 |
36,918,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4610:Golgb1
|
UTSW |
16 |
36,918,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4660:Golgb1
|
UTSW |
16 |
36,887,618 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4811:Golgb1
|
UTSW |
16 |
36,891,419 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4815:Golgb1
|
UTSW |
16 |
36,913,115 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R4835:Golgb1
|
UTSW |
16 |
36,891,407 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4904:Golgb1
|
UTSW |
16 |
36,893,386 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4916:Golgb1
|
UTSW |
16 |
36,916,118 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5121:Golgb1
|
UTSW |
16 |
36,919,258 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5133:Golgb1
|
UTSW |
16 |
36,891,457 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5143:Golgb1
|
UTSW |
16 |
36,898,689 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5185:Golgb1
|
UTSW |
16 |
36,875,141 (GRCm38) |
unclassified |
probably benign |
|
|
R5188:Golgb1
|
UTSW |
16 |
36,918,465 (GRCm38) |
missense |
probably benign |
0.13 |
|
R5260:Golgb1
|
UTSW |
16 |
36,913,141 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5297:Golgb1
|
UTSW |
16 |
36,875,616 (GRCm38) |
intron |
probably benign |
|
|
R5438:Golgb1
|
UTSW |
16 |
36,900,508 (GRCm38) |
missense |
probably benign |
0.15 |
|
R5439:Golgb1
|
UTSW |
16 |
36,900,508 (GRCm38) |
missense |
probably benign |
0.15 |
|
R5494:Golgb1
|
UTSW |
16 |
36,928,683 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R5592:Golgb1
|
UTSW |
16 |
36,925,763 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5740:Golgb1
|
UTSW |
16 |
36,919,000 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5862:Golgb1
|
UTSW |
16 |
36,926,091 (GRCm38) |
splice site |
silent |
|
|
R5928:Golgb1
|
UTSW |
16 |
36,911,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6009:Golgb1
|
UTSW |
16 |
36,914,959 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6062:Golgb1
|
UTSW |
16 |
36,914,671 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6102:Golgb1
|
UTSW |
16 |
36,912,865 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6198:Golgb1
|
UTSW |
16 |
36,893,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6253:Golgb1
|
UTSW |
16 |
36,915,622 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R6254:Golgb1
|
UTSW |
16 |
36,913,978 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6321:Golgb1
|
UTSW |
16 |
36,918,197 (GRCm38) |
nonsense |
probably null |
|
|
R6700:Golgb1
|
UTSW |
16 |
36,875,584 (GRCm38) |
intron |
probably benign |
|
|
R6870:Golgb1
|
UTSW |
16 |
36,918,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6882:Golgb1
|
UTSW |
16 |
36,913,990 (GRCm38) |
missense |
probably benign |
|
|
R6944:Golgb1
|
UTSW |
16 |
36,912,113 (GRCm38) |
missense |
probably benign |
|
|
R7108:Golgb1
|
UTSW |
16 |
36,913,721 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7124:Golgb1
|
UTSW |
16 |
36,913,673 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7125:Golgb1
|
UTSW |
16 |
36,917,963 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7187:Golgb1
|
UTSW |
16 |
36,916,150 (GRCm38) |
missense |
probably benign |
0.43 |
|
R7205:Golgb1
|
UTSW |
16 |
36,875,301 (GRCm38) |
missense |
unknown |
|
|
R7206:Golgb1
|
UTSW |
16 |
36,913,749 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7233:Golgb1
|
UTSW |
16 |
36,914,758 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R7320:Golgb1
|
UTSW |
16 |
36,915,951 (GRCm38) |
nonsense |
probably null |
|
|
R7367:Golgb1
|
UTSW |
16 |
36,898,546 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7408:Golgb1
|
UTSW |
16 |
36,898,547 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7419:Golgb1
|
UTSW |
16 |
36,912,919 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7556:Golgb1
|
UTSW |
16 |
36,915,793 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7599:Golgb1
|
UTSW |
16 |
36,875,396 (GRCm38) |
missense |
unknown |
|
|
R7673:Golgb1
|
UTSW |
16 |
36,913,669 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7789:Golgb1
|
UTSW |
16 |
36,875,399 (GRCm38) |
missense |
unknown |
|
|
R7792:Golgb1
|
UTSW |
16 |
36,918,730 (GRCm38) |
missense |
probably benign |
0.43 |
|
R7830:Golgb1
|
UTSW |
16 |
36,898,721 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7847:Golgb1
|
UTSW |
16 |
36,931,920 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7905:Golgb1
|
UTSW |
16 |
36,913,685 (GRCm38) |
missense |
probably benign |
|
|
R7944:Golgb1
|
UTSW |
16 |
36,914,104 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7945:Golgb1
|
UTSW |
16 |
36,914,104 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7950:Golgb1
|
UTSW |
16 |
36,915,424 (GRCm38) |
missense |
probably benign |
0.13 |
|
R8040:Golgb1
|
UTSW |
16 |
36,913,479 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R8077:Golgb1
|
UTSW |
16 |
36,918,633 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8181:Golgb1
|
UTSW |
16 |
36,916,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8370:Golgb1
|
UTSW |
16 |
36,912,317 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8684:Golgb1
|
UTSW |
16 |
36,914,402 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8725:Golgb1
|
UTSW |
16 |
36,919,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8727:Golgb1
|
UTSW |
16 |
36,919,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8738:Golgb1
|
UTSW |
16 |
36,916,313 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8785:Golgb1
|
UTSW |
16 |
36,919,744 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8824:Golgb1
|
UTSW |
16 |
36,915,689 (GRCm38) |
missense |
probably benign |
|
|
R8825:Golgb1
|
UTSW |
16 |
36,919,447 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8940:Golgb1
|
UTSW |
16 |
36,916,397 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8962:Golgb1
|
UTSW |
16 |
36,913,616 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9245:Golgb1
|
UTSW |
16 |
36,918,819 (GRCm38) |
nonsense |
probably null |
|
|
R9365:Golgb1
|
UTSW |
16 |
36,915,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9612:Golgb1
|
UTSW |
16 |
36,919,605 (GRCm38) |
missense |
probably benign |
0.41 |
|
R9620:Golgb1
|
UTSW |
16 |
36,919,449 (GRCm38) |
missense |
probably benign |
|
|
R9691:Golgb1
|
UTSW |
16 |
36,898,634 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Golgb1
|
UTSW |
16 |
36,893,407 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V1662:Golgb1
|
UTSW |
16 |
36,898,542 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0067:Golgb1
|
UTSW |
16 |
36,914,303 (GRCm38) |
nonsense |
probably null |
|
|
Z1088:Golgb1
|
UTSW |
16 |
36,919,742 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTGCACCCAGTGATGAGAG -3'
(R):5'- ATCAAGCTCCTTCACCTGGTAAAG -3'
Sequencing Primer
(F):5'- CCCAGTGATGAGAGCAGCG -3'
(R):5'- TTCACCTGGTAAAGCAGCTG -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation