Incidental Mutation 'R5395:Ly75'
| ID |
426098 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
042967-MU
|
| Accession Numbers |
Genbank: NM_013825
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5395 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 60365111 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 234
(N234K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028362
AA Change: N234K
PolyPhen 2
Score 0.415 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: N234K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112533
AA Change: N234K
PolyPhen 2
Score 0.185 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: N234K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124654
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151984
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
A |
G |
3: 122,080,941 (GRCm38) |
I268V |
probably benign |
Het |
| Actn1 |
T |
A |
12: 80,170,703 (GRCm38) |
I782F |
probably benign |
Het |
| Adamdec1 |
A |
C |
14: 68,570,903 (GRCm38) |
S333A |
probably benign |
Het |
| Agbl5 |
C |
A |
5: 30,890,338 (GRCm38) |
T58N |
probably damaging |
Het |
| Apoo-ps |
T |
A |
13: 107,414,493 (GRCm38) |
|
noncoding transcript |
Het |
| Arhgef10l |
T |
C |
4: 140,570,290 (GRCm38) |
N277S |
probably benign |
Het |
| Ascc2 |
A |
G |
11: 4,659,273 (GRCm38) |
E241G |
possibly damaging |
Het |
| Atp13a4 |
A |
G |
16: 29,456,604 (GRCm38) |
V354A |
possibly damaging |
Het |
| Atp13a4 |
A |
T |
16: 29,420,888 (GRCm38) |
Y835* |
probably null |
Het |
| Bcas3 |
T |
C |
11: 85,825,249 (GRCm38) |
S426P |
probably damaging |
Het |
| Birc3 |
T |
C |
9: 7,861,174 (GRCm38) |
R48G |
probably damaging |
Het |
| Cacna2d4 |
T |
C |
6: 119,271,418 (GRCm38) |
S397P |
possibly damaging |
Het |
| Ccng2 |
T |
C |
5: 93,269,398 (GRCm38) |
M91T |
possibly damaging |
Het |
| Clk3 |
G |
A |
9: 57,753,339 (GRCm38) |
T473M |
probably damaging |
Het |
| Cog2 |
T |
A |
8: 124,545,221 (GRCm38) |
H491Q |
probably benign |
Het |
| Cyp4f40 |
C |
T |
17: 32,669,853 (GRCm38) |
T202I |
probably benign |
Het |
| Dennd1a |
A |
T |
2: 37,802,128 (GRCm38) |
F181I |
probably damaging |
Het |
| Fcrl6 |
G |
T |
1: 172,598,720 (GRCm38) |
A170D |
possibly damaging |
Het |
| Fev |
T |
C |
1: 74,882,664 (GRCm38) |
|
probably null |
Het |
| Flnb |
A |
G |
14: 7,883,881 (GRCm38) |
N369S |
probably benign |
Het |
| Flt3 |
A |
G |
5: 147,354,823 (GRCm38) |
F606L |
probably damaging |
Het |
| Gdf9 |
T |
C |
11: 53,433,797 (GRCm38) |
V131A |
probably benign |
Het |
| Gdnf |
T |
A |
15: 7,834,684 (GRCm38) |
L192Q |
probably damaging |
Het |
| Gjc2 |
A |
T |
11: 59,177,489 (GRCm38) |
C56S |
possibly damaging |
Het |
| Gli3 |
T |
C |
13: 15,714,950 (GRCm38) |
F550L |
probably damaging |
Het |
| Gm1110 |
T |
C |
9: 26,889,632 (GRCm38) |
E422G |
probably benign |
Het |
| Gm14325 |
G |
A |
2: 177,832,984 (GRCm38) |
H102Y |
possibly damaging |
Het |
| Gnb2 |
A |
G |
5: 137,528,526 (GRCm38) |
S334P |
probably damaging |
Het |
| Icam2 |
A |
T |
11: 106,382,473 (GRCm38) |
|
probably null |
Het |
| Inca1 |
C |
T |
11: 70,690,438 (GRCm38) |
|
probably null |
Het |
| Itgb8 |
A |
C |
12: 119,170,741 (GRCm38) |
C530W |
probably damaging |
Het |
| Lrp1 |
T |
C |
10: 127,595,297 (GRCm38) |
D332G |
probably damaging |
Het |
| Mcm5 |
G |
A |
8: 75,123,026 (GRCm38) |
S542N |
probably benign |
Het |
| Mcm9 |
A |
T |
10: 53,538,692 (GRCm38) |
N97K |
possibly damaging |
Het |
| Morc2a |
G |
A |
11: 3,688,232 (GRCm38) |
R986H |
possibly damaging |
Het |
| Neu2 |
T |
A |
1: 87,596,675 (GRCm38) |
|
probably null |
Het |
| Nfatc1 |
G |
A |
18: 80,636,020 (GRCm38) |
P718S |
possibly damaging |
Het |
| Nol6 |
G |
A |
4: 41,118,392 (GRCm38) |
|
probably benign |
Het |
| Olfr1406 |
A |
T |
1: 173,183,680 (GRCm38) |
Y251* |
probably null |
Het |
| Otogl |
T |
C |
10: 107,817,138 (GRCm38) |
N1118D |
probably benign |
Het |
| Pcdh15 |
T |
A |
10: 74,185,287 (GRCm38) |
I111K |
probably damaging |
Het |
| Phkb |
A |
G |
8: 86,017,468 (GRCm38) |
D582G |
probably damaging |
Het |
| Piwil2 |
G |
T |
14: 70,395,397 (GRCm38) |
N575K |
probably benign |
Het |
| Pou4f2 |
T |
A |
8: 78,435,072 (GRCm38) |
I301F |
probably damaging |
Het |
| Prkd1 |
T |
C |
12: 50,391,432 (GRCm38) |
N409S |
probably damaging |
Het |
| Ptpn21 |
T |
G |
12: 98,715,117 (GRCm38) |
K86T |
probably damaging |
Het |
| Raly |
T |
A |
2: 154,864,007 (GRCm38) |
|
probably null |
Het |
| Rangap1 |
A |
G |
15: 81,706,446 (GRCm38) |
F482L |
probably benign |
Het |
| Rapgef1 |
T |
A |
2: 29,737,965 (GRCm38) |
N1052K |
probably damaging |
Het |
| Rnf169 |
A |
T |
7: 99,935,160 (GRCm38) |
|
probably null |
Het |
| Sdr16c5 |
T |
C |
4: 4,016,277 (GRCm38) |
S50G |
probably benign |
Het |
| Sin3a |
G |
A |
9: 57,105,673 (GRCm38) |
R612H |
probably damaging |
Het |
| Six6 |
T |
A |
12: 72,941,701 (GRCm38) |
L216* |
probably null |
Het |
| Slc20a1 |
A |
T |
2: 129,208,337 (GRCm38) |
N472Y |
probably damaging |
Het |
| Slc35d1 |
C |
T |
4: 103,211,375 (GRCm38) |
|
probably null |
Het |
| Slc45a2 |
C |
T |
15: 11,027,785 (GRCm38) |
T480I |
probably damaging |
Het |
| Slc7a8 |
C |
A |
14: 54,733,277 (GRCm38) |
G306* |
probably null |
Het |
| Slc9a8 |
T |
A |
2: 167,467,722 (GRCm38) |
F335L |
probably damaging |
Het |
| Smyd1 |
T |
G |
6: 71,219,390 (GRCm38) |
K338T |
possibly damaging |
Het |
| Snd1 |
T |
A |
6: 28,526,184 (GRCm38) |
V187E |
probably damaging |
Het |
| Spag9 |
T |
G |
11: 94,091,751 (GRCm38) |
|
probably null |
Het |
| Tnfsf9 |
C |
A |
17: 57,105,592 (GRCm38) |
T54K |
probably benign |
Het |
| Trim24 |
T |
G |
6: 37,957,744 (GRCm38) |
V798G |
probably damaging |
Het |
| Tyr |
C |
A |
7: 87,472,490 (GRCm38) |
A365S |
probably damaging |
Het |
| Usp43 |
T |
A |
11: 67,897,358 (GRCm38) |
|
probably null |
Het |
| Vmn2r55 |
T |
C |
7: 12,651,947 (GRCm38) |
D702G |
probably damaging |
Het |
| Vmn2r72 |
A |
G |
7: 85,750,897 (GRCm38) |
S315P |
possibly damaging |
Het |
| Wdr64 |
T |
A |
1: 175,755,598 (GRCm38) |
F367I |
probably damaging |
Het |
| Zc3h7b |
G |
A |
15: 81,772,501 (GRCm38) |
R173K |
possibly damaging |
Het |
| Zfp493 |
T |
A |
13: 67,783,846 (GRCm38) |
C21* |
probably null |
Het |
| Zfp825 |
T |
C |
13: 74,480,546 (GRCm38) |
T284A |
possibly damaging |
Het |
| Zpbp2 |
T |
A |
11: 98,558,213 (GRCm38) |
V275D |
probably damaging |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,306,404 (GRCm38) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,375,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,375,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,323,852 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,323,926 (GRCm38) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCCTGGTTATTCAGTGTAGAAG -3'
(R):5'- CACTATGCACTGTGTCTTAGCC -3'
Sequencing Primer
(F):5'- TATTCAGTGTAGAAGAAGAAAGCATC -3'
(R):5'- CCAGATACGTTCCATGTGGTGAC -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation