Incidental Mutation 'R5436:Hfm1'
| ID |
428333 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
043001-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.086)
|
| Stock # |
R5436 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
106840192-106926321 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 106892772 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 709
(D709G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112590
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148495]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112690
AA Change: D709G
PolyPhen 2
Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: D709G
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000117588
AA Change: D709G
PolyPhen 2
Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: D709G
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148495
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155171
|
| SMART Domains |
Protein: ENSMUSP00000118674
Gene: ENSMUSG00000043410
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
9 |
22 |
N/A |
INTRINSIC |
|
Sec63
|
33 |
304 |
3.04e-42 |
SMART |
|
Blast:Sec63
|
344 |
402 |
7e-19 |
BLAST |
|
| Meta Mutation Damage Score |
0.2388 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
99% (106/107) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930402H24Rik |
C |
A |
2: 130,764,499 (GRCm38) |
K415N |
probably benign |
Het |
| 4930449A18Rik |
T |
C |
3: 59,846,693 (GRCm38) |
|
noncoding transcript |
Het |
| Abca9 |
G |
A |
11: 110,134,236 (GRCm38) |
L994F |
probably damaging |
Het |
| Abl2 |
A |
T |
1: 156,629,880 (GRCm38) |
S239C |
probably damaging |
Het |
| Acsl5 |
T |
A |
19: 55,279,565 (GRCm38) |
|
probably null |
Het |
| Aff1 |
C |
T |
5: 103,783,870 (GRCm38) |
T126I |
probably damaging |
Het |
| Amtn |
T |
C |
5: 88,381,626 (GRCm38) |
L107P |
probably damaging |
Het |
| Ankrd45 |
A |
G |
1: 161,159,112 (GRCm38) |
|
probably benign |
Het |
| Arl6ip5 |
G |
A |
6: 97,210,926 (GRCm38) |
V36I |
probably damaging |
Het |
| Ascc3 |
T |
A |
10: 50,658,983 (GRCm38) |
D657E |
probably damaging |
Het |
| Ascl1 |
T |
A |
10: 87,492,946 (GRCm38) |
Q48L |
unknown |
Het |
| Asic4 |
T |
A |
1: 75,451,319 (GRCm38) |
V163E |
probably benign |
Het |
| Atm |
A |
T |
9: 53,459,804 (GRCm38) |
M2245K |
probably benign |
Het |
| Barx2 |
T |
G |
9: 31,912,989 (GRCm38) |
T35P |
probably damaging |
Het |
| BC027072 |
A |
T |
17: 71,750,842 (GRCm38) |
S613R |
probably damaging |
Het |
| Bdh1 |
C |
T |
16: 31,456,657 (GRCm38) |
R235C |
probably damaging |
Het |
| C8b |
T |
A |
4: 104,800,349 (GRCm38) |
Y404* |
probably null |
Het |
| Car5a |
A |
G |
8: 121,917,242 (GRCm38) |
|
probably benign |
Het |
| Ccdc13 |
T |
C |
9: 121,799,043 (GRCm38) |
I169M |
probably benign |
Het |
| Cd163 |
A |
T |
6: 124,327,964 (GRCm38) |
D1100V |
probably benign |
Het |
| Cntfr |
T |
C |
4: 41,663,322 (GRCm38) |
N162D |
probably damaging |
Het |
| Cops3 |
T |
G |
11: 59,824,345 (GRCm38) |
D289A |
probably damaging |
Het |
| Crbn |
A |
T |
6: 106,795,900 (GRCm38) |
S42R |
probably damaging |
Het |
| Cth |
T |
A |
3: 157,894,826 (GRCm38) |
H397L |
probably benign |
Het |
| Dact2 |
A |
G |
17: 14,195,748 (GRCm38) |
L730P |
probably damaging |
Het |
| Dhx37 |
C |
T |
5: 125,429,803 (GRCm38) |
G210R |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 31,316,747 (GRCm38) |
I126V |
probably benign |
Het |
| Dnttip2 |
T |
C |
3: 122,278,769 (GRCm38) |
I566T |
probably damaging |
Het |
| Ehbp1l1 |
G |
T |
19: 5,716,248 (GRCm38) |
R412S |
possibly damaging |
Het |
| Fam110b |
A |
C |
4: 5,799,104 (GRCm38) |
Q174P |
probably benign |
Het |
| Fam149a |
A |
T |
8: 45,348,471 (GRCm38) |
S457T |
probably benign |
Het |
| Fat3 |
A |
C |
9: 15,960,514 (GRCm38) |
V3527G |
probably benign |
Het |
| Fat4 |
A |
G |
3: 38,891,346 (GRCm38) |
M1463V |
probably benign |
Het |
| Gak |
T |
A |
5: 108,592,352 (GRCm38) |
I566F |
possibly damaging |
Het |
| Gdf10 |
T |
A |
14: 33,932,256 (GRCm38) |
I240N |
probably damaging |
Het |
| Gprc6a |
T |
A |
10: 51,626,702 (GRCm38) |
H355L |
probably benign |
Het |
| Gxylt1 |
T |
C |
15: 93,247,899 (GRCm38) |
K338R |
probably damaging |
Het |
| Hexim2 |
A |
T |
11: 103,138,269 (GRCm38) |
E49V |
probably null |
Het |
| Ighv1-49 |
T |
C |
12: 115,055,461 (GRCm38) |
K19R |
probably damaging |
Het |
| Il17a |
T |
A |
1: 20,733,646 (GRCm38) |
Y88* |
probably null |
Het |
| Iqsec1 |
A |
T |
6: 90,845,361 (GRCm38) |
|
probably benign |
Het |
| Itih2 |
T |
C |
2: 10,105,196 (GRCm38) |
D582G |
probably benign |
Het |
| Klc3 |
T |
C |
7: 19,397,959 (GRCm38) |
|
probably null |
Het |
| Larp4 |
T |
A |
15: 99,986,114 (GRCm38) |
N78K |
probably damaging |
Het |
| Larp4b |
A |
G |
13: 9,168,900 (GRCm38) |
D526G |
possibly damaging |
Het |
| Lexm |
A |
T |
4: 106,610,493 (GRCm38) |
H315Q |
probably benign |
Het |
| Limch1 |
T |
C |
5: 66,974,566 (GRCm38) |
V133A |
possibly damaging |
Het |
| Lmbr1l |
G |
A |
15: 98,904,791 (GRCm38) |
R426C |
probably damaging |
Het |
| Lox |
T |
A |
18: 52,529,103 (GRCm38) |
D76V |
probably benign |
Het |
| Lrrc8d |
T |
A |
5: 105,812,552 (GRCm38) |
I276N |
probably damaging |
Het |
| Ltbr |
G |
A |
6: 125,312,794 (GRCm38) |
R146W |
probably damaging |
Het |
| March10 |
A |
T |
11: 105,402,165 (GRCm38) |
Y139N |
possibly damaging |
Het |
| Mrc1 |
T |
G |
2: 14,266,515 (GRCm38) |
I410S |
probably damaging |
Het |
| Mrto4 |
A |
T |
4: 139,347,965 (GRCm38) |
C176S |
probably damaging |
Het |
| Mtch1 |
G |
T |
17: 29,347,590 (GRCm38) |
D66E |
probably benign |
Het |
| Nbas |
T |
G |
12: 13,374,811 (GRCm38) |
L1017R |
probably damaging |
Het |
| Nim1k |
A |
G |
13: 119,727,529 (GRCm38) |
|
probably benign |
Het |
| Nlrp6 |
T |
A |
7: 140,922,717 (GRCm38) |
Y245* |
probably null |
Het |
| Olfr1264 |
T |
A |
2: 90,021,665 (GRCm38) |
M134L |
probably benign |
Het |
| Olfr192 |
C |
T |
16: 59,098,819 (GRCm38) |
V58I |
unknown |
Het |
| Olfr224 |
T |
A |
11: 58,566,937 (GRCm38) |
H136L |
probably benign |
Het |
| Olfr635 |
A |
T |
7: 103,979,266 (GRCm38) |
I25F |
probably benign |
Het |
| Olfr740 |
T |
G |
14: 50,453,727 (GRCm38) |
V225G |
probably damaging |
Het |
| Olfr906 |
A |
C |
9: 38,488,539 (GRCm38) |
D170A |
probably benign |
Het |
| Pcnx |
G |
T |
12: 81,860,406 (GRCm38) |
G12V |
probably damaging |
Het |
| Pdzd3 |
A |
G |
9: 44,248,355 (GRCm38) |
V448A |
possibly damaging |
Het |
| Pkp1 |
T |
A |
1: 135,918,918 (GRCm38) |
K32M |
probably damaging |
Het |
| Poc5 |
T |
C |
13: 96,396,813 (GRCm38) |
W150R |
probably damaging |
Het |
| Ppp1r16b |
T |
A |
2: 158,757,333 (GRCm38) |
|
probably benign |
Het |
| Prune2 |
T |
A |
19: 17,020,643 (GRCm38) |
M248K |
probably damaging |
Het |
| Rb1 |
A |
T |
14: 73,213,140 (GRCm38) |
|
probably null |
Het |
| Rhod |
A |
G |
19: 4,426,587 (GRCm38) |
C169R |
probably benign |
Het |
| Rif1 |
T |
C |
2: 52,120,971 (GRCm38) |
|
probably benign |
Het |
| Rnpc3 |
G |
A |
3: 113,624,999 (GRCm38) |
A100V |
probably damaging |
Het |
| Rsf1 |
GCGGC |
GCGGCGGCGTCGGC |
7: 97,579,931 (GRCm38) |
|
probably benign |
Het |
| Scnn1a |
A |
T |
6: 125,343,022 (GRCm38) |
D528V |
possibly damaging |
Het |
| Sdhaf3 |
C |
A |
6: 7,038,855 (GRCm38) |
T59K |
probably benign |
Het |
| Sec31a |
C |
A |
5: 100,363,839 (GRCm38) |
A330S |
probably damaging |
Het |
| Sgk3 |
A |
G |
1: 9,881,872 (GRCm38) |
D241G |
probably damaging |
Het |
| Skint6 |
T |
G |
4: 113,096,591 (GRCm38) |
I459L |
probably benign |
Het |
| Slco1a5 |
A |
T |
6: 142,254,392 (GRCm38) |
V222E |
probably damaging |
Het |
| Slit3 |
T |
A |
11: 35,707,911 (GRCm38) |
N1447K |
probably benign |
Het |
| Sorbs2 |
A |
G |
8: 45,796,001 (GRCm38) |
H628R |
probably damaging |
Het |
| St6galnac2 |
A |
G |
11: 116,684,527 (GRCm38) |
|
probably benign |
Het |
| Tbc1d31 |
T |
C |
15: 57,952,871 (GRCm38) |
V667A |
probably benign |
Het |
| Tbx20 |
A |
T |
9: 24,769,720 (GRCm38) |
Y159N |
probably damaging |
Het |
| Tmprss11b |
T |
A |
5: 86,662,233 (GRCm38) |
Q296L |
probably benign |
Het |
| Ttc6 |
T |
A |
12: 57,674,594 (GRCm38) |
|
probably null |
Het |
| Ttn |
T |
A |
2: 76,870,899 (GRCm38) |
|
probably benign |
Het |
| Tubgcp4 |
T |
A |
2: 121,194,182 (GRCm38) |
F613I |
probably benign |
Het |
| Tubgcp4 |
T |
A |
2: 121,188,136 (GRCm38) |
L340H |
probably damaging |
Het |
| Urb1 |
T |
C |
16: 90,792,762 (GRCm38) |
Y377C |
probably damaging |
Het |
| Utp15 |
G |
A |
13: 98,260,846 (GRCm38) |
|
probably null |
Het |
| Vstm2b |
A |
G |
7: 40,901,283 (GRCm38) |
|
probably null |
Het |
| Vwde |
A |
T |
6: 13,190,628 (GRCm38) |
V488D |
probably damaging |
Het |
| Wee1 |
TCCCC |
TCCC |
7: 110,124,569 (GRCm38) |
|
probably null |
Het |
| Zfp276 |
A |
T |
8: 123,265,282 (GRCm38) |
|
probably benign |
Het |
| Zfp318 |
T |
A |
17: 46,413,049 (GRCm38) |
S1993T |
possibly damaging |
Het |
| Zfp959 |
T |
C |
17: 55,897,626 (GRCm38) |
L218P |
probably benign |
Het |
| Zxdc |
A |
G |
6: 90,370,560 (GRCm38) |
D301G |
probably damaging |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
106,902,130 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
106,917,606 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
106,917,379 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
106,904,793 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
106,911,544 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
106,904,267 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
106,873,928 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
106,901,761 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
106,895,287 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
106,878,662 (GRCm38) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
106,878,823 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
106,874,252 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
106,895,934 (GRCm38) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
106,911,575 (GRCm38) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
106,856,929 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
106,917,478 (GRCm38) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
106,917,601 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
106,898,256 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
106,878,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
106,904,218 (GRCm38) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
106,911,411 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
106,874,901 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
106,872,353 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1450:Hfm1
|
UTSW |
5 |
106,918,458 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1529:Hfm1
|
UTSW |
5 |
106,853,123 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
106,893,523 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
106,896,003 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
106,880,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
106,880,360 (GRCm38) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,847,676 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
106,901,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
106,896,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,847,653 (GRCm38) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
106,872,416 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
106,874,282 (GRCm38) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
106,872,330 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
106,892,839 (GRCm38) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
106,904,797 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
106,886,508 (GRCm38) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
106,874,890 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
106,874,221 (GRCm38) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,847,667 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4745:Hfm1
|
UTSW |
5 |
106,901,843 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R4747:Hfm1
|
UTSW |
5 |
106,917,523 (GRCm38) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,842,539 (GRCm38) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
106,854,740 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
106,892,751 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
106,874,213 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R5093:Hfm1
|
UTSW |
5 |
106,901,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5399:Hfm1
|
UTSW |
5 |
106,917,562 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
106,902,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5459:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,847,662 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
106,911,439 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
106,911,453 (GRCm38) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
106,878,589 (GRCm38) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
106,874,917 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
106,898,643 (GRCm38) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
106,886,553 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,841,638 (GRCm38) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,847,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,847,687 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
106,895,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
106,878,815 (GRCm38) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
106,917,374 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,850,410 (GRCm38) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
106,880,477 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7058:Hfm1
|
UTSW |
5 |
106,911,440 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7189:Hfm1
|
UTSW |
5 |
106,901,703 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
106,904,331 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
106,895,218 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
106,917,466 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
106,898,475 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
106,889,925 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
106,881,861 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
106,881,791 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
106,898,553 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
106,896,033 (GRCm38) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
106,881,818 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
106,898,505 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
106,917,573 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,841,745 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
106,893,468 (GRCm38) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
106,874,900 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
106,874,072 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9649:Hfm1
|
UTSW |
5 |
106,918,463 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R9743:Hfm1
|
UTSW |
5 |
106,874,259 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
106,874,030 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
106,917,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
106,871,820 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCTCTGAATATACTGGTGACTGC -3'
(R):5'- GGAGAAACCTCAGTTCTTTAAGATC -3'
Sequencing Primer
(F):5'- TTTTTCTGTTGGTTATTAGTTGTTGG -3'
(R):5'- TCAGTTCTTTAAGATCTTTAACTGCC -3'
|
| Posted On |
2016-09-01 |
Incidental Mutation