Incidental Mutation 'R5436:Urb1'
| ID |
428389 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
4921511H13Rik, 5730405K23Rik |
| MMRRC Submission |
043001-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5436 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
90751527-90810413 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 90792762 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 377
(Y377C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140920
AA Change: Y377C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: Y377C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142955
|
| Meta Mutation Damage Score |
0.7752 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
99% (106/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930402H24Rik |
C |
A |
2: 130,764,499 (GRCm38) |
K415N |
probably benign |
Het |
| 4930449A18Rik |
T |
C |
3: 59,846,693 (GRCm38) |
|
noncoding transcript |
Het |
| Abca9 |
G |
A |
11: 110,134,236 (GRCm38) |
L994F |
probably damaging |
Het |
| Abl2 |
A |
T |
1: 156,629,880 (GRCm38) |
S239C |
probably damaging |
Het |
| Acsl5 |
T |
A |
19: 55,279,565 (GRCm38) |
|
probably null |
Het |
| Aff1 |
C |
T |
5: 103,783,870 (GRCm38) |
T126I |
probably damaging |
Het |
| Amtn |
T |
C |
5: 88,381,626 (GRCm38) |
L107P |
probably damaging |
Het |
| Ankrd45 |
A |
G |
1: 161,159,112 (GRCm38) |
|
probably benign |
Het |
| Arl6ip5 |
G |
A |
6: 97,210,926 (GRCm38) |
V36I |
probably damaging |
Het |
| Ascc3 |
T |
A |
10: 50,658,983 (GRCm38) |
D657E |
probably damaging |
Het |
| Ascl1 |
T |
A |
10: 87,492,946 (GRCm38) |
Q48L |
unknown |
Het |
| Asic4 |
T |
A |
1: 75,451,319 (GRCm38) |
V163E |
probably benign |
Het |
| Atm |
A |
T |
9: 53,459,804 (GRCm38) |
M2245K |
probably benign |
Het |
| Barx2 |
T |
G |
9: 31,912,989 (GRCm38) |
T35P |
probably damaging |
Het |
| BC027072 |
A |
T |
17: 71,750,842 (GRCm38) |
S613R |
probably damaging |
Het |
| Bdh1 |
C |
T |
16: 31,456,657 (GRCm38) |
R235C |
probably damaging |
Het |
| C8b |
T |
A |
4: 104,800,349 (GRCm38) |
Y404* |
probably null |
Het |
| Car5a |
A |
G |
8: 121,917,242 (GRCm38) |
|
probably benign |
Het |
| Ccdc13 |
T |
C |
9: 121,799,043 (GRCm38) |
I169M |
probably benign |
Het |
| Cd163 |
A |
T |
6: 124,327,964 (GRCm38) |
D1100V |
probably benign |
Het |
| Cntfr |
T |
C |
4: 41,663,322 (GRCm38) |
N162D |
probably damaging |
Het |
| Cops3 |
T |
G |
11: 59,824,345 (GRCm38) |
D289A |
probably damaging |
Het |
| Crbn |
A |
T |
6: 106,795,900 (GRCm38) |
S42R |
probably damaging |
Het |
| Cth |
T |
A |
3: 157,894,826 (GRCm38) |
H397L |
probably benign |
Het |
| Dact2 |
A |
G |
17: 14,195,748 (GRCm38) |
L730P |
probably damaging |
Het |
| Dhx37 |
C |
T |
5: 125,429,803 (GRCm38) |
G210R |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 31,316,747 (GRCm38) |
I126V |
probably benign |
Het |
| Dnttip2 |
T |
C |
3: 122,278,769 (GRCm38) |
I566T |
probably damaging |
Het |
| Ehbp1l1 |
G |
T |
19: 5,716,248 (GRCm38) |
R412S |
possibly damaging |
Het |
| Fam110b |
A |
C |
4: 5,799,104 (GRCm38) |
Q174P |
probably benign |
Het |
| Fam149a |
A |
T |
8: 45,348,471 (GRCm38) |
S457T |
probably benign |
Het |
| Fat3 |
A |
C |
9: 15,960,514 (GRCm38) |
V3527G |
probably benign |
Het |
| Fat4 |
A |
G |
3: 38,891,346 (GRCm38) |
M1463V |
probably benign |
Het |
| Gak |
T |
A |
5: 108,592,352 (GRCm38) |
I566F |
possibly damaging |
Het |
| Gdf10 |
T |
A |
14: 33,932,256 (GRCm38) |
I240N |
probably damaging |
Het |
| Gprc6a |
T |
A |
10: 51,626,702 (GRCm38) |
H355L |
probably benign |
Het |
| Gxylt1 |
T |
C |
15: 93,247,899 (GRCm38) |
K338R |
probably damaging |
Het |
| Hexim2 |
A |
T |
11: 103,138,269 (GRCm38) |
E49V |
probably null |
Het |
| Hfm1 |
T |
C |
5: 106,892,772 (GRCm38) |
D709G |
possibly damaging |
Het |
| Ighv1-49 |
T |
C |
12: 115,055,461 (GRCm38) |
K19R |
probably damaging |
Het |
| Il17a |
T |
A |
1: 20,733,646 (GRCm38) |
Y88* |
probably null |
Het |
| Iqsec1 |
A |
T |
6: 90,845,361 (GRCm38) |
|
probably benign |
Het |
| Itih2 |
T |
C |
2: 10,105,196 (GRCm38) |
D582G |
probably benign |
Het |
| Klc3 |
T |
C |
7: 19,397,959 (GRCm38) |
|
probably null |
Het |
| Larp4 |
T |
A |
15: 99,986,114 (GRCm38) |
N78K |
probably damaging |
Het |
| Larp4b |
A |
G |
13: 9,168,900 (GRCm38) |
D526G |
possibly damaging |
Het |
| Lexm |
A |
T |
4: 106,610,493 (GRCm38) |
H315Q |
probably benign |
Het |
| Limch1 |
T |
C |
5: 66,974,566 (GRCm38) |
V133A |
possibly damaging |
Het |
| Lmbr1l |
G |
A |
15: 98,904,791 (GRCm38) |
R426C |
probably damaging |
Het |
| Lox |
T |
A |
18: 52,529,103 (GRCm38) |
D76V |
probably benign |
Het |
| Lrrc8d |
T |
A |
5: 105,812,552 (GRCm38) |
I276N |
probably damaging |
Het |
| Ltbr |
G |
A |
6: 125,312,794 (GRCm38) |
R146W |
probably damaging |
Het |
| March10 |
A |
T |
11: 105,402,165 (GRCm38) |
Y139N |
possibly damaging |
Het |
| Mrc1 |
T |
G |
2: 14,266,515 (GRCm38) |
I410S |
probably damaging |
Het |
| Mrto4 |
A |
T |
4: 139,347,965 (GRCm38) |
C176S |
probably damaging |
Het |
| Mtch1 |
G |
T |
17: 29,347,590 (GRCm38) |
D66E |
probably benign |
Het |
| Nbas |
T |
G |
12: 13,374,811 (GRCm38) |
L1017R |
probably damaging |
Het |
| Nim1k |
A |
G |
13: 119,727,529 (GRCm38) |
|
probably benign |
Het |
| Nlrp6 |
T |
A |
7: 140,922,717 (GRCm38) |
Y245* |
probably null |
Het |
| Olfr1264 |
T |
A |
2: 90,021,665 (GRCm38) |
M134L |
probably benign |
Het |
| Olfr192 |
C |
T |
16: 59,098,819 (GRCm38) |
V58I |
unknown |
Het |
| Olfr224 |
T |
A |
11: 58,566,937 (GRCm38) |
H136L |
probably benign |
Het |
| Olfr635 |
A |
T |
7: 103,979,266 (GRCm38) |
I25F |
probably benign |
Het |
| Olfr740 |
T |
G |
14: 50,453,727 (GRCm38) |
V225G |
probably damaging |
Het |
| Olfr906 |
A |
C |
9: 38,488,539 (GRCm38) |
D170A |
probably benign |
Het |
| Pcnx |
G |
T |
12: 81,860,406 (GRCm38) |
G12V |
probably damaging |
Het |
| Pdzd3 |
A |
G |
9: 44,248,355 (GRCm38) |
V448A |
possibly damaging |
Het |
| Pkp1 |
T |
A |
1: 135,918,918 (GRCm38) |
K32M |
probably damaging |
Het |
| Poc5 |
T |
C |
13: 96,396,813 (GRCm38) |
W150R |
probably damaging |
Het |
| Ppp1r16b |
T |
A |
2: 158,757,333 (GRCm38) |
|
probably benign |
Het |
| Prune2 |
T |
A |
19: 17,020,643 (GRCm38) |
M248K |
probably damaging |
Het |
| Rb1 |
A |
T |
14: 73,213,140 (GRCm38) |
|
probably null |
Het |
| Rhod |
A |
G |
19: 4,426,587 (GRCm38) |
C169R |
probably benign |
Het |
| Rif1 |
T |
C |
2: 52,120,971 (GRCm38) |
|
probably benign |
Het |
| Rnpc3 |
G |
A |
3: 113,624,999 (GRCm38) |
A100V |
probably damaging |
Het |
| Rsf1 |
GCGGC |
GCGGCGGCGTCGGC |
7: 97,579,931 (GRCm38) |
|
probably benign |
Het |
| Scnn1a |
A |
T |
6: 125,343,022 (GRCm38) |
D528V |
possibly damaging |
Het |
| Sdhaf3 |
C |
A |
6: 7,038,855 (GRCm38) |
T59K |
probably benign |
Het |
| Sec31a |
C |
A |
5: 100,363,839 (GRCm38) |
A330S |
probably damaging |
Het |
| Sgk3 |
A |
G |
1: 9,881,872 (GRCm38) |
D241G |
probably damaging |
Het |
| Skint6 |
T |
G |
4: 113,096,591 (GRCm38) |
I459L |
probably benign |
Het |
| Slco1a5 |
A |
T |
6: 142,254,392 (GRCm38) |
V222E |
probably damaging |
Het |
| Slit3 |
T |
A |
11: 35,707,911 (GRCm38) |
N1447K |
probably benign |
Het |
| Sorbs2 |
A |
G |
8: 45,796,001 (GRCm38) |
H628R |
probably damaging |
Het |
| St6galnac2 |
A |
G |
11: 116,684,527 (GRCm38) |
|
probably benign |
Het |
| Tbc1d31 |
T |
C |
15: 57,952,871 (GRCm38) |
V667A |
probably benign |
Het |
| Tbx20 |
A |
T |
9: 24,769,720 (GRCm38) |
Y159N |
probably damaging |
Het |
| Tmprss11b |
T |
A |
5: 86,662,233 (GRCm38) |
Q296L |
probably benign |
Het |
| Ttc6 |
T |
A |
12: 57,674,594 (GRCm38) |
|
probably null |
Het |
| Ttn |
T |
A |
2: 76,870,899 (GRCm38) |
|
probably benign |
Het |
| Tubgcp4 |
T |
A |
2: 121,194,182 (GRCm38) |
F613I |
probably benign |
Het |
| Tubgcp4 |
T |
A |
2: 121,188,136 (GRCm38) |
L340H |
probably damaging |
Het |
| Utp15 |
G |
A |
13: 98,260,846 (GRCm38) |
|
probably null |
Het |
| Vstm2b |
A |
G |
7: 40,901,283 (GRCm38) |
|
probably null |
Het |
| Vwde |
A |
T |
6: 13,190,628 (GRCm38) |
V488D |
probably damaging |
Het |
| Wee1 |
TCCCC |
TCCC |
7: 110,124,569 (GRCm38) |
|
probably null |
Het |
| Zfp276 |
A |
T |
8: 123,265,282 (GRCm38) |
|
probably benign |
Het |
| Zfp318 |
T |
A |
17: 46,413,049 (GRCm38) |
S1993T |
possibly damaging |
Het |
| Zfp959 |
T |
C |
17: 55,897,626 (GRCm38) |
L218P |
probably benign |
Het |
| Zxdc |
A |
G |
6: 90,370,560 (GRCm38) |
D301G |
probably damaging |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,753,321 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,779,098 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,792,814 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,804,458 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,757,761 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,777,560 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,760,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,769,586 (GRCm38) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,772,695 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,788,156 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,780,304 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,788,114 (GRCm38) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,769,469 (GRCm38) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,769,469 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,779,140 (GRCm38) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,779,140 (GRCm38) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,791,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,796,399 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,783,262 (GRCm38) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,777,422 (GRCm38) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,776,207 (GRCm38) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,779,138 (GRCm38) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,774,094 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,810,297 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,795,448 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,795,448 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,769,447 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,776,318 (GRCm38) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,769,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,769,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,796,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,752,014 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,752,014 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,774,745 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,753,863 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,777,440 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,760,452 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,774,048 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,772,626 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,788,082 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,787,397 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,767,040 (GRCm38) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,761,695 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,762,344 (GRCm38) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,774,256 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,774,256 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,774,798 (GRCm38) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,797,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,797,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,783,376 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,769,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,788,086 (GRCm38) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,774,537 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,769,394 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,788,146 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,787,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,776,271 (GRCm38) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,776,129 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,772,634 (GRCm38) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,804,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,753,518 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,769,555 (GRCm38) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,757,827 (GRCm38) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,759,842 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,795,414 (GRCm38) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,783,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,805,411 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,756,171 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,752,017 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,752,095 (GRCm38) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,783,274 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,792,748 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5767:Urb1
|
UTSW |
16 |
90,776,163 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,804,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,772,764 (GRCm38) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,762,383 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,789,097 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,803,332 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,779,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,753,919 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,762,430 (GRCm38) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,787,414 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,810,268 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,779,083 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,782,106 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,791,166 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,752,115 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,774,768 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,787,408 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,761,634 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,792,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,797,910 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,786,118 (GRCm38) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,779,152 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,791,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,774,625 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,803,423 (GRCm38) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,810,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,774,117 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,753,790 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,769,402 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,792,750 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,772,575 (GRCm38) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,786,208 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,774,862 (GRCm38) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,753,883 (GRCm38) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATGGTCTCCAATACCCTG -3'
(R):5'- ACTGTGTGTCTCTGAAAGTGAC -3'
Sequencing Primer
(F):5'- ATACCCTGTCCCTGAGCCAG -3'
(R):5'- CTCTGAAAGTGACTTCAGTGCTCAG -3'
|
| Posted On |
2016-09-01 |
Incidental Mutation