Incidental Mutation 'R5372:Ep300'
| ID |
428821 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ep300
|
| Ensembl Gene |
ENSMUSG00000055024 |
| Gene Name |
E1A binding protein p300 |
| Synonyms |
KAT3B, p300 |
| MMRRC Submission |
042948-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5372 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
81585351-81652077 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 81636830 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 1264
(I1264V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068387]
|
| AlphaFold |
B2RWS6 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000068387
AA Change: I1264V
|
| SMART Domains |
Protein: ENSMUSP00000066789
Gene: ENSMUSG00000055024
AA Change: I1264V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
242 |
N/A |
INTRINSIC |
|
low complexity region
|
296 |
309 |
N/A |
INTRINSIC |
|
ZnF_TAZ
|
333 |
418 |
2.85e-32 |
SMART |
|
low complexity region
|
475 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
Pfam:KIX
|
567 |
647 |
7.2e-44 |
PFAM |
|
low complexity region
|
722 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
852 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1039 |
N/A |
INTRINSIC |
|
BROMO
|
1047 |
1157 |
6.36e-42 |
SMART |
|
Blast:KAT11
|
1227 |
1300 |
9e-22 |
BLAST |
|
KAT11
|
1305 |
1610 |
1.19e-140 |
SMART |
|
ZnF_ZZ
|
1663 |
1704 |
2.67e-15 |
SMART |
|
ZnF_TAZ
|
1728 |
1806 |
5.53e-30 |
SMART |
|
low complexity region
|
1810 |
1836 |
N/A |
INTRINSIC |
|
low complexity region
|
1847 |
1881 |
N/A |
INTRINSIC |
|
low complexity region
|
1902 |
1927 |
N/A |
INTRINSIC |
|
low complexity region
|
1962 |
1979 |
N/A |
INTRINSIC |
|
Pfam:Creb_binding
|
1993 |
2099 |
3.5e-37 |
PFAM |
|
low complexity region
|
2146 |
2158 |
N/A |
INTRINSIC |
|
low complexity region
|
2187 |
2203 |
N/A |
INTRINSIC |
|
low complexity region
|
2205 |
2244 |
N/A |
INTRINSIC |
|
low complexity region
|
2254 |
2265 |
N/A |
INTRINSIC |
|
low complexity region
|
2303 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2405 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187776
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205816
|
| Meta Mutation Damage Score |
0.0807 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.2%
|
| Validation Efficiency |
96% (89/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects of the heart, lung, and small intestine and die at midgestation; heterozygotes also show some embryonic loss. Heterozygotes for an acetyltransferase-negative mutation die by the neonatal period. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
T |
A |
3: 122,055,339 (GRCm38) |
D108E |
probably damaging |
Het |
| Abhd12b |
A |
G |
12: 70,181,026 (GRCm38) |
D194G |
probably damaging |
Het |
| Adck5 |
A |
G |
15: 76,594,507 (GRCm38) |
|
probably benign |
Het |
| Adgrb3 |
C |
T |
1: 25,128,859 (GRCm38) |
V792I |
probably benign |
Het |
| Anxa8 |
G |
A |
14: 34,093,911 (GRCm38) |
V174M |
probably damaging |
Het |
| Apol9b |
A |
T |
15: 77,735,720 (GRCm38) |
R239W |
probably benign |
Het |
| Arhgap26 |
A |
G |
18: 38,642,456 (GRCm38) |
|
noncoding transcript |
Het |
| Atrnl1 |
A |
G |
19: 57,755,536 (GRCm38) |
Y1190C |
probably benign |
Het |
| Brinp3 |
T |
G |
1: 146,831,726 (GRCm38) |
L376R |
probably damaging |
Het |
| Btbd2 |
A |
T |
10: 80,648,641 (GRCm38) |
M132K |
probably damaging |
Het |
| C130073F10Rik |
A |
T |
4: 101,890,487 (GRCm38) |
I115K |
probably damaging |
Het |
| C1ra |
T |
A |
6: 124,521,625 (GRCm38) |
Y426N |
probably damaging |
Het |
| Cacna1b |
A |
T |
2: 24,733,959 (GRCm38) |
V203E |
probably damaging |
Het |
| Catsperg1 |
T |
A |
7: 29,210,712 (GRCm38) |
D68V |
probably benign |
Het |
| Ccdc158 |
A |
C |
5: 92,632,560 (GRCm38) |
S885A |
possibly damaging |
Het |
| Cdc42bpa |
T |
C |
1: 180,064,979 (GRCm38) |
V236A |
probably damaging |
Het |
| Cdca7 |
A |
T |
2: 72,482,449 (GRCm38) |
E176D |
probably damaging |
Het |
| Cdk17 |
A |
G |
10: 93,226,039 (GRCm38) |
D211G |
probably benign |
Het |
| Clca3a2 |
A |
C |
3: 144,797,525 (GRCm38) |
M888R |
probably benign |
Het |
| Clcn7 |
T |
A |
17: 25,157,179 (GRCm38) |
M568K |
possibly damaging |
Het |
| Clip1 |
G |
T |
5: 123,630,240 (GRCm38) |
N811K |
probably benign |
Het |
| Col12a1 |
T |
A |
9: 79,678,366 (GRCm38) |
Y1243F |
probably damaging |
Het |
| Dctn1 |
T |
A |
6: 83,190,210 (GRCm38) |
D315E |
probably damaging |
Het |
| Dgcr2 |
T |
C |
16: 17,872,644 (GRCm38) |
T41A |
probably benign |
Het |
| Dync2h1 |
G |
A |
9: 7,176,962 (GRCm38) |
|
probably benign |
Het |
| Fam167b |
A |
T |
4: 129,578,299 (GRCm38) |
L26Q |
possibly damaging |
Het |
| Fam178b |
T |
A |
1: 36,564,848 (GRCm38) |
I457F |
possibly damaging |
Het |
| Fgd4 |
A |
T |
16: 16,484,291 (GRCm38) |
N133K |
probably benign |
Het |
| Fndc1 |
C |
G |
17: 7,765,210 (GRCm38) |
V1295L |
unknown |
Het |
| Gad2 |
A |
T |
2: 22,690,243 (GRCm38) |
D552V |
possibly damaging |
Het |
| Hars2 |
T |
C |
18: 36,790,481 (GRCm38) |
Y361H |
possibly damaging |
Het |
| Heca |
T |
A |
10: 17,915,139 (GRCm38) |
S390C |
probably damaging |
Het |
| Hephl1 |
G |
T |
9: 15,097,899 (GRCm38) |
Y132* |
probably null |
Het |
| Hormad1 |
T |
A |
3: 95,576,424 (GRCm38) |
D182E |
probably damaging |
Het |
| Ifna15 |
G |
A |
4: 88,558,101 (GRCm38) |
P49S |
probably damaging |
Het |
| Khsrp |
T |
C |
17: 57,024,292 (GRCm38) |
T429A |
possibly damaging |
Het |
| Magi2 |
A |
G |
5: 20,702,110 (GRCm38) |
Q1094R |
possibly damaging |
Het |
| Map3k11 |
T |
A |
19: 5,690,962 (GRCm38) |
I239K |
probably damaging |
Het |
| Mtus2 |
A |
G |
5: 148,313,412 (GRCm38) |
T1319A |
probably damaging |
Het |
| Nup54 |
A |
G |
5: 92,417,857 (GRCm38) |
I406T |
probably damaging |
Het |
| Nxpe2 |
T |
C |
9: 48,339,519 (GRCm38) |
T43A |
possibly damaging |
Het |
| Nynrin |
A |
G |
14: 55,868,491 (GRCm38) |
E889G |
probably benign |
Het |
| Olfr1313 |
A |
G |
2: 112,072,109 (GRCm38) |
I158T |
probably benign |
Het |
| Olfr160 |
T |
C |
9: 37,711,938 (GRCm38) |
M114V |
possibly damaging |
Het |
| Olfr301 |
T |
A |
7: 86,412,968 (GRCm38) |
I202N |
possibly damaging |
Het |
| Olfr663 |
A |
G |
7: 104,703,795 (GRCm38) |
D76G |
probably benign |
Het |
| Opa1 |
A |
C |
16: 29,586,119 (GRCm38) |
H45P |
probably benign |
Het |
| Otx1 |
C |
A |
11: 21,997,037 (GRCm38) |
A91S |
probably damaging |
Het |
| Papola |
A |
G |
12: 105,827,050 (GRCm38) |
K543R |
probably benign |
Het |
| Plcxd3 |
G |
A |
15: 4,574,788 (GRCm38) |
V293I |
probably benign |
Het |
| Polr2g |
T |
C |
19: 8,797,303 (GRCm38) |
Y72C |
probably damaging |
Het |
| Ppp1r21 |
A |
G |
17: 88,550,675 (GRCm38) |
K205E |
probably benign |
Het |
| Ptpre |
A |
G |
7: 135,653,940 (GRCm38) |
K53E |
possibly damaging |
Het |
| Rasal3 |
T |
C |
17: 32,391,344 (GRCm38) |
K990E |
probably benign |
Het |
| Rgs3 |
A |
T |
4: 62,652,697 (GRCm38) |
|
probably benign |
Het |
| Rhd |
A |
G |
4: 134,884,632 (GRCm38) |
T254A |
possibly damaging |
Het |
| Rufy4 |
T |
C |
1: 74,147,663 (GRCm38) |
C537R |
probably damaging |
Het |
| Scube3 |
G |
T |
17: 28,152,482 (GRCm38) |
C57F |
probably damaging |
Het |
| Sh2d5 |
A |
G |
4: 138,254,699 (GRCm38) |
D57G |
possibly damaging |
Het |
| Slc12a6 |
T |
A |
2: 112,347,360 (GRCm38) |
L608* |
probably null |
Het |
| Slk |
A |
T |
19: 47,625,393 (GRCm38) |
N896I |
probably damaging |
Het |
| Smc6 |
A |
G |
12: 11,282,430 (GRCm38) |
D211G |
probably damaging |
Het |
| Sox6 |
A |
T |
7: 115,550,151 (GRCm38) |
Y371* |
probably null |
Het |
| Srcap |
G |
A |
7: 127,557,613 (GRCm38) |
|
probably null |
Het |
| Stard5 |
T |
A |
7: 83,633,220 (GRCm38) |
D80E |
probably damaging |
Het |
| Supv3l1 |
C |
T |
10: 62,432,357 (GRCm38) |
V570M |
probably damaging |
Het |
| Syt7 |
G |
T |
19: 10,426,621 (GRCm38) |
V180L |
probably damaging |
Het |
| Tacc2 |
T |
A |
7: 130,623,260 (GRCm38) |
H558Q |
probably benign |
Het |
| Tas2r120 |
T |
A |
6: 132,657,483 (GRCm38) |
M176K |
possibly damaging |
Het |
| Tmem135 |
A |
T |
7: 89,165,174 (GRCm38) |
|
probably null |
Het |
| Trim35 |
T |
C |
14: 66,297,266 (GRCm38) |
V66A |
possibly damaging |
Het |
| Tspan12 |
A |
G |
6: 21,772,699 (GRCm38) |
S284P |
probably benign |
Het |
| Ttll3 |
A |
T |
6: 113,401,421 (GRCm38) |
K257* |
probably null |
Het |
| Uggt1 |
C |
A |
1: 36,244,060 (GRCm38) |
|
probably benign |
Het |
| Vmn2r7 |
T |
A |
3: 64,716,324 (GRCm38) |
I283F |
probably damaging |
Het |
| Wdfy2 |
T |
G |
14: 62,954,885 (GRCm38) |
H363Q |
probably damaging |
Het |
| Wdr4 |
T |
A |
17: 31,510,580 (GRCm38) |
K95N |
probably damaging |
Het |
| Zfp141 |
T |
C |
7: 42,477,196 (GRCm38) |
N91S |
possibly damaging |
Het |
| Zfp383 |
C |
T |
7: 29,915,270 (GRCm38) |
R317* |
probably null |
Het |
|
| Other mutations in Ep300 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Ep300
|
APN |
15 |
81,641,418 (GRCm38) |
missense |
unknown |
|
|
IGL01128:Ep300
|
APN |
15 |
81,630,006 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01151:Ep300
|
APN |
15 |
81,623,472 (GRCm38) |
intron |
probably benign |
|
|
IGL01414:Ep300
|
APN |
15 |
81,627,266 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01564:Ep300
|
APN |
15 |
81,632,464 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01875:Ep300
|
APN |
15 |
81,640,023 (GRCm38) |
missense |
unknown |
|
|
IGL01945:Ep300
|
APN |
15 |
81,616,109 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02022:Ep300
|
APN |
15 |
81,611,437 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02115:Ep300
|
APN |
15 |
81,648,818 (GRCm38) |
missense |
unknown |
|
|
IGL02129:Ep300
|
APN |
15 |
81,586,636 (GRCm38) |
missense |
unknown |
|
|
IGL02145:Ep300
|
APN |
15 |
81,601,166 (GRCm38) |
missense |
unknown |
|
|
IGL02149:Ep300
|
APN |
15 |
81,628,420 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02165:Ep300
|
APN |
15 |
81,641,391 (GRCm38) |
missense |
probably benign |
0.39 |
|
IGL02226:Ep300
|
APN |
15 |
81,613,412 (GRCm38) |
missense |
unknown |
|
|
IGL02610:Ep300
|
APN |
15 |
81,601,522 (GRCm38) |
missense |
unknown |
|
|
IGL02731:Ep300
|
APN |
15 |
81,648,414 (GRCm38) |
missense |
unknown |
|
|
IGL03239:Ep300
|
APN |
15 |
81,641,388 (GRCm38) |
missense |
unknown |
|
|
BB001:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
BB011:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
R0077:Ep300
|
UTSW |
15 |
81,641,313 (GRCm38) |
missense |
unknown |
|
|
R0145:Ep300
|
UTSW |
15 |
81,616,127 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0244:Ep300
|
UTSW |
15 |
81,640,128 (GRCm38) |
missense |
unknown |
|
|
R0390:Ep300
|
UTSW |
15 |
81,640,116 (GRCm38) |
missense |
unknown |
|
|
R0534:Ep300
|
UTSW |
15 |
81,600,896 (GRCm38) |
splice site |
probably benign |
|
|
R0671:Ep300
|
UTSW |
15 |
81,616,134 (GRCm38) |
unclassified |
probably benign |
|
|
R0840:Ep300
|
UTSW |
15 |
81,644,933 (GRCm38) |
missense |
unknown |
|
|
R1166:Ep300
|
UTSW |
15 |
81,630,064 (GRCm38) |
unclassified |
probably benign |
|
|
R1737:Ep300
|
UTSW |
15 |
81,626,347 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1893:Ep300
|
UTSW |
15 |
81,631,646 (GRCm38) |
unclassified |
probably benign |
|
|
R2136:Ep300
|
UTSW |
15 |
81,640,447 (GRCm38) |
missense |
unknown |
|
|
R3427:Ep300
|
UTSW |
15 |
81,601,279 (GRCm38) |
missense |
unknown |
|
|
R3757:Ep300
|
UTSW |
15 |
81,648,589 (GRCm38) |
missense |
unknown |
|
|
R3892:Ep300
|
UTSW |
15 |
81,619,997 (GRCm38) |
unclassified |
probably benign |
|
|
R4554:Ep300
|
UTSW |
15 |
81,601,430 (GRCm38) |
missense |
unknown |
|
|
R4575:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4575:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R4577:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4577:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R4578:Ep300
|
UTSW |
15 |
81,611,410 (GRCm38) |
unclassified |
probably benign |
|
|
R4578:Ep300
|
UTSW |
15 |
81,649,009 (GRCm38) |
missense |
unknown |
|
|
R5021:Ep300
|
UTSW |
15 |
81,640,023 (GRCm38) |
missense |
unknown |
|
|
R5366:Ep300
|
UTSW |
15 |
81,616,100 (GRCm38) |
missense |
probably benign |
0.24 |
|
R5393:Ep300
|
UTSW |
15 |
81,631,618 (GRCm38) |
unclassified |
probably benign |
|
|
R5410:Ep300
|
UTSW |
15 |
81,648,854 (GRCm38) |
missense |
unknown |
|
|
R5571:Ep300
|
UTSW |
15 |
81,643,217 (GRCm38) |
intron |
probably benign |
|
|
R5701:Ep300
|
UTSW |
15 |
81,601,495 (GRCm38) |
missense |
unknown |
|
|
R5772:Ep300
|
UTSW |
15 |
81,639,914 (GRCm38) |
intron |
probably benign |
|
|
R5825:Ep300
|
UTSW |
15 |
81,611,472 (GRCm38) |
missense |
probably benign |
0.39 |
|
R5917:Ep300
|
UTSW |
15 |
81,628,607 (GRCm38) |
unclassified |
probably benign |
|
|
R5991:Ep300
|
UTSW |
15 |
81,648,466 (GRCm38) |
missense |
unknown |
|
|
R6019:Ep300
|
UTSW |
15 |
81,641,382 (GRCm38) |
missense |
unknown |
|
|
R6144:Ep300
|
UTSW |
15 |
81,601,234 (GRCm38) |
missense |
unknown |
|
|
R6291:Ep300
|
UTSW |
15 |
81,648,507 (GRCm38) |
missense |
unknown |
|
|
R6292:Ep300
|
UTSW |
15 |
81,616,734 (GRCm38) |
unclassified |
probably benign |
|
|
R6599:Ep300
|
UTSW |
15 |
81,586,713 (GRCm38) |
missense |
unknown |
|
|
R6804:Ep300
|
UTSW |
15 |
81,641,311 (GRCm38) |
nonsense |
probably null |
|
|
R6925:Ep300
|
UTSW |
15 |
81,649,981 (GRCm38) |
missense |
probably benign |
0.32 |
|
R7327:Ep300
|
UTSW |
15 |
81,627,314 (GRCm38) |
missense |
unknown |
|
|
R7378:Ep300
|
UTSW |
15 |
81,650,545 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7388:Ep300
|
UTSW |
15 |
81,648,366 (GRCm38) |
missense |
unknown |
|
|
R7419:Ep300
|
UTSW |
15 |
81,648,514 (GRCm38) |
missense |
unknown |
|
|
R7498:Ep300
|
UTSW |
15 |
81,639,843 (GRCm38) |
missense |
unknown |
|
|
R7584:Ep300
|
UTSW |
15 |
81,628,426 (GRCm38) |
missense |
unknown |
|
|
R7605:Ep300
|
UTSW |
15 |
81,621,152 (GRCm38) |
missense |
unknown |
|
|
R7619:Ep300
|
UTSW |
15 |
81,608,198 (GRCm38) |
missense |
unknown |
|
|
R7699:Ep300
|
UTSW |
15 |
81,586,393 (GRCm38) |
start gained |
probably benign |
|
|
R7763:Ep300
|
UTSW |
15 |
81,586,583 (GRCm38) |
start gained |
probably benign |
|
|
R7775:Ep300
|
UTSW |
15 |
81,586,686 (GRCm38) |
missense |
unknown |
|
|
R7778:Ep300
|
UTSW |
15 |
81,586,686 (GRCm38) |
missense |
unknown |
|
|
R7862:Ep300
|
UTSW |
15 |
81,650,753 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7924:Ep300
|
UTSW |
15 |
81,649,502 (GRCm38) |
missense |
unknown |
|
|
R8155:Ep300
|
UTSW |
15 |
81,621,068 (GRCm38) |
missense |
unknown |
|
|
R8259:Ep300
|
UTSW |
15 |
81,639,017 (GRCm38) |
missense |
unknown |
|
|
R8276:Ep300
|
UTSW |
15 |
81,650,028 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R8331:Ep300
|
UTSW |
15 |
81,601,210 (GRCm38) |
missense |
unknown |
|
|
R8554:Ep300
|
UTSW |
15 |
81,639,027 (GRCm38) |
missense |
unknown |
|
|
R9019:Ep300
|
UTSW |
15 |
81,648,529 (GRCm38) |
missense |
unknown |
|
|
R9128:Ep300
|
UTSW |
15 |
81,649,745 (GRCm38) |
missense |
unknown |
|
|
R9379:Ep300
|
UTSW |
15 |
81,648,559 (GRCm38) |
missense |
unknown |
|
|
R9380:Ep300
|
UTSW |
15 |
81,616,044 (GRCm38) |
missense |
unknown |
|
|
R9484:Ep300
|
UTSW |
15 |
81,636,825 (GRCm38) |
missense |
unknown |
|
|
R9659:Ep300
|
UTSW |
15 |
81,621,072 (GRCm38) |
missense |
unknown |
|
|
R9690:Ep300
|
UTSW |
15 |
81,636,195 (GRCm38) |
missense |
unknown |
|
|
R9721:Ep300
|
UTSW |
15 |
81,608,315 (GRCm38) |
missense |
unknown |
|
|
RF020:Ep300
|
UTSW |
15 |
81,586,571 (GRCm38) |
start gained |
probably benign |
|
|
Z1177:Ep300
|
UTSW |
15 |
81,630,097 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTAGCTCTTTGGGCATGACAG -3'
(R):5'- CTGACAGGCATATGTTGTACAAATG -3'
Sequencing Primer
(F):5'- CTCTTTGGGCATGACAGTTGTC -3'
(R):5'- GGCAATGTACACGTTTGATCCCAG -3'
|
| Posted On |
2016-09-06 |
Incidental Mutation