Mutagenetix > Incidental Mutation

Incidental Mutation 'R5368:Gm9762'

429465

Institutional Source

Beutler Lab

Gene Symbol

Gm9762

Ensembl Gene

ENSMUSG00000037096

Gene Name

predicted pseudogene 9762

Synonyms

MMRRC Submission

043204-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.339) question?

Stock #

R5368 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

78966359-78966799 bp(-) (GRCm38)

Type of Mutation

exon

DNA Base Change (assembly)

T to A at 78966435 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000036976

Meta Mutation Damage Score

0.8574

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.3%

Validation Efficiency

97% (61/63)

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933402N03Rik	T	A	7: 131,139,196 (GRCm38)	H97L	possibly damaging	Het
Abca9	T	A	11: 110,145,546 (GRCm38)	N579I	probably damaging	Het
Acbd3	A	T	1: 180,722,095 (GRCm38)		probably benign	Het
Ankrd50	A	T	3: 38,455,050 (GRCm38)	I1056N	probably damaging	Het
Ceacam18	T	C	7: 43,642,034 (GRCm38)	V300A	probably benign	Het
Cfap46	C	A	7: 139,627,473 (GRCm38)	R1843S	possibly damaging	Het
D430041D05Rik	A	G	2: 104,248,284 (GRCm38)	V1229A	probably damaging	Het
Dbx2	G	A	15: 95,640,641 (GRCm38)	S206L	probably benign	Het
Dnah11	A	T	12: 117,954,893 (GRCm38)	D1530E	probably damaging	Het
Ecm2	A	C	13: 49,520,943 (GRCm38)	T280P	probably benign	Het
Emc2	G	A	15: 43,511,811 (GRCm38)		probably null	Het
Epb42	C	T	2: 121,019,462 (GRCm38)	V689I	probably benign	Het
Fam114a1	T	A	5: 65,006,109 (GRCm38)	M209K	possibly damaging	Het
Fam117a	C	T	11: 95,375,633 (GRCm38)	S193F	probably damaging	Het
Foxp2	A	T	6: 15,377,914 (GRCm38)		probably benign	Het
Frmd6	T	A	12: 70,864,100 (GRCm38)	C19*	probably null	Het
Fyb1	A	G	15: 6,580,678 (GRCm38)		probably null	Het
Gata6	C	A	18: 11,063,059 (GRCm38)	H442Q	possibly damaging	Het
Gldc	A	G	19: 30,158,521 (GRCm38)	S160P	probably benign	Het
Gm3952	A	G	8: 128,745,974 (GRCm38)	S1626P	possibly damaging	Het
Gtpbp2	T	C	17: 46,166,304 (GRCm38)		probably benign	Het
Hgd	A	T	16: 37,589,751 (GRCm38)	T50S	probably benign	Het
Itpr1	C	T	6: 108,387,498 (GRCm38)	T22M	probably damaging	Het
Kif26b	G	A	1: 178,915,884 (GRCm38)	E1182K	probably damaging	Het
Kirrel3	A	G	9: 35,007,738 (GRCm38)	E230G	probably damaging	Het
Leng8	A	G	7: 4,139,988 (GRCm38)	Y88C	probably damaging	Het
Lpo	T	C	11: 87,821,069 (GRCm38)	D54G	possibly damaging	Het
Lypd2	G	T	15: 74,733,059 (GRCm38)	A29E	probably benign	Het
Mdn1	C	T	4: 32,723,690 (GRCm38)	P2542L	probably damaging	Het
Mical3	T	C	6: 120,959,473 (GRCm38)	Y1364C	probably damaging	Het
Mroh2b	A	G	15: 4,905,572 (GRCm38)	N163S	probably damaging	Het
Mtf1	G	A	4: 124,825,079 (GRCm38)	C295Y	probably damaging	Het
Nbn	T	A	4: 15,969,391 (GRCm38)	L212Q	probably damaging	Het
Obscn	A	T	11: 59,069,026 (GRCm38)		probably null	Het
Or10ag56	T	A	2: 87,308,782 (GRCm38)		probably null	Het
Or4c110	A	G	2: 89,002,091 (GRCm38)	S66P	probably damaging	Het
Peli1	A	G	11: 21,148,389 (GRCm38)	T375A	probably damaging	Het
Picalm	T	C	7: 90,207,595 (GRCm38)	*611Q	probably null	Het
Plch1	G	T	3: 63,701,973 (GRCm38)	Q938K	possibly damaging	Het
Plxnb2	A	G	15: 89,159,593 (GRCm38)	V1352A	possibly damaging	Het
Pmepa1	G	A	2: 173,228,322 (GRCm38)	R147W	probably damaging	Het
Prdm16	T	G	4: 154,345,391 (GRCm38)	K373Q	probably damaging	Het
Qki	T	G	17: 10,239,035 (GRCm38)	E135A	probably damaging	Het
Rad50	T	C	11: 53,684,246 (GRCm38)	K556E	probably benign	Het
Scara5	CG	C	14: 65,759,662 (GRCm38)		probably null	Het
Sin3a	T	A	9: 57,110,800 (GRCm38)	D834E	possibly damaging	Het
Smg8	G	A	11: 87,080,260 (GRCm38)	S895L	probably benign	Het
Sorl1	T	C	9: 41,979,390 (GRCm38)	I1944M	probably benign	Het
Stam2	G	A	2: 52,736,293 (GRCm38)		probably benign	Het
Tmprss7	A	T	16: 45,660,889 (GRCm38)	W645R	probably damaging	Het
Tns1	T	C	1: 73,941,017 (GRCm38)	M1111V	probably benign	Het
Ttn	A	T	2: 76,811,243 (GRCm38)	L5176Q	possibly damaging	Het
Ttn	A	C	2: 76,778,382 (GRCm38)	D17763E	probably damaging	Het
Ubr4	G	A	4: 139,397,528 (GRCm38)		probably benign	Het
Usp31	T	C	7: 121,661,365 (GRCm38)	H637R	probably damaging	Het
Vps50	A	C	6: 3,567,739 (GRCm38)	E545A	possibly damaging	Het
Wdfy3	G	T	5: 101,872,858 (GRCm38)	L2527M	probably damaging	Het
Wfdc2	T	C	2: 164,563,434 (GRCm38)	V85A	possibly damaging	Het

Other mutations in Gm9762

Allele	Source	Chr	Coord	Type	Predicted Effect
R4697:Gm9762	UTSW	3	78,966,550 (GRCm38)	exon	noncoding transcript
R4754:Gm9762	UTSW	3	78,966,421 (GRCm38)	exon	noncoding transcript
R5119:Gm9762	UTSW	3	78,966,400 (GRCm38)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- GCACTGCTGTGTCAGGTAAAC -3'
(R):5'- ACCGCCTAAGGTTGCATTTAC -3'

Sequencing Primer
(F):5'- CTGTGTCAGGTAAACATGTGCAC -3'
(R):5'- GCATTTACAACAAGAATTTATCACCC -3'

Posted On

2016-09-06