Mutagenetix > Incidental Mutation

Incidental Mutation 'R5484:Celsr1'

430337

Institutional Source

Beutler Lab

Gene Symbol

Celsr1

Ensembl Gene

ENSMUSG00000016028

Gene Name

cadherin, EGF LAG seven-pass G-type receptor 1

Synonyms

Scy, Adgrc1, Crsh, crash

MMRRC Submission

043045-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.634) question?

Stock #

R5484 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

85783130-85918404 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 85815483 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1844 (D1844G)

Ref Sequence

ENSEMBL: ENSMUSP00000016172 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000016172]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000016172
AA Change: D1844G

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000016172
Gene: ENSMUSG00000016028
AA Change: D1844G

Domain	Start	End	E-Value	Type
signal peptide	1	29	N/A	INTRINSIC
low complexity region	65	93	N/A	INTRINSIC
low complexity region	221	240	N/A	INTRINSIC
low complexity region	243	257	N/A	INTRINSIC
CA	282	366	9.51e-26	SMART
CA	390	472	1.59e-27	SMART
CA	496	578	3.8e-25	SMART
CA	602	700	2.25e-27	SMART
CA	724	802	3.14e-17	SMART
CA	826	905	2.67e-29	SMART
CA	929	1012	3.23e-28	SMART
CA	1036	1114	4.17e-22	SMART
CA	1142	1218	6.89e-1	SMART
EGF	1321	1376	3.38e-3	SMART
EGF	1381	1414	5.49e-3	SMART
EGF	1421	1456	9.7e-4	SMART
LamG	1477	1644	2.53e-33	SMART
EGF	1667	1700	6.4e-4	SMART
LamG	1726	1864	1.13e-21	SMART
EGF	1890	1923	1.84e-4	SMART
EGF	1925	1961	5.49e-3	SMART
EGF_Lam	2018	2063	7.12e-11	SMART
HormR	2066	2128	2.55e-20	SMART
Pfam:GAIN	2140	2396	1.1e-64	PFAM
GPS	2422	2475	5.03e-22	SMART
Pfam:7tm_2	2480	2712	2.6e-60	PFAM
low complexity region	2738	2753	N/A	INTRINSIC
low complexity region	2819	2852	N/A	INTRINSIC
low complexity region	2976	2988	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000226840
AA Change: D477G

Meta Mutation Damage Score

0.0897

Coding Region Coverage

1x: 98.3%
3x: 97.3%
10x: 95.3%
20x: 91.4%

Validation Efficiency

97% (76/78)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Nullizygous mice exhibit kinky tails, variable neural tube defects, abnormal hair follicle orientation, whorl-like hair patterns, and partial prenatal lethality. ENU-induced mutants show defects in planar polarity of inner ear hair cells and complete perinatal lethality due to craniorachischisis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921509C19Rik	T	C	2: 151,313,851 (GRCm39)	H609R	probably benign	Het
Abca6	A	T	11: 110,074,899 (GRCm39)	V1388E	probably damaging	Het
Alx1	T	A	10: 102,861,177 (GRCm39)	D117V	probably damaging	Het
Ascl4	T	C	10: 85,764,401 (GRCm39)	L16P	probably damaging	Het
Atp4a	G	A	7: 30,420,097 (GRCm39)		probably benign	Het
Btnl10	G	A	11: 58,814,651 (GRCm39)	V444M	probably damaging	Het
Camkv	A	T	9: 107,823,345 (GRCm39)	N124Y	probably damaging	Het
Catsperb	T	C	12: 101,542,175 (GRCm39)	L625P	probably benign	Het
Ccdc171	A	G	4: 83,612,199 (GRCm39)	I973V	probably benign	Het
Chd7	G	C	4: 8,828,258 (GRCm39)	K1066N	probably damaging	Het
Cmklr1	C	G	5: 113,752,990 (GRCm39)	D4H	possibly damaging	Het
Corin	T	C	5: 72,515,827 (GRCm39)	D409G	probably benign	Het
Cry1	T	C	10: 84,982,588 (GRCm39)		probably null	Het
Cttnbp2	T	A	6: 18,427,689 (GRCm39)		probably benign	Het
Cyrib	T	A	15: 63,815,056 (GRCm39)	T139S	probably damaging	Het
Dmxl1	T	A	18: 50,022,531 (GRCm39)	V1623E	probably damaging	Het
Dnah6	G	T	6: 73,069,099 (GRCm39)	D2477E	possibly damaging	Het
Dnajb12	GC	G	10: 59,728,574 (GRCm39)		probably null	Het
Dop1a	C	G	9: 86,427,341 (GRCm39)	R2164G	probably damaging	Het
Dsp	A	G	13: 38,368,014 (GRCm39)	T678A	possibly damaging	Het
Farsb	A	C	1: 78,452,833 (GRCm39)	I51S	probably damaging	Het
Gm10220	T	A	5: 26,322,930 (GRCm39)	I161L	possibly damaging	Het
Gm10782	G	T	13: 56,510,987 (GRCm39)		noncoding transcript	Het
Gm12830	A	T	4: 114,702,248 (GRCm39)	T137S	unknown	Het
Gopc	A	G	10: 52,234,942 (GRCm39)	L67P	probably damaging	Het
Hmcn1	T	C	1: 150,551,291 (GRCm39)	I2655V	probably benign	Het
Hmcn2	C	T	2: 31,283,066 (GRCm39)	Q1981*	probably null	Het
Ifi209	T	A	1: 173,468,640 (GRCm39)	S157T	probably benign	Het
Ift56	T	G	6: 38,366,057 (GRCm39)	C124W	probably benign	Het
Iqcf1	A	T	9: 106,379,107 (GRCm39)	I74F	probably damaging	Het
Irf3	A	T	7: 44,649,382 (GRCm39)	R78W	probably damaging	Het
Kank4	T	C	4: 98,663,022 (GRCm39)	D722G	probably benign	Het
Loxl1	A	G	9: 58,198,065 (GRCm39)	V597A	possibly damaging	Het
Marveld1	T	C	19: 42,136,272 (GRCm39)	L62P	probably damaging	Het
Mga	T	G	2: 119,747,107 (GRCm39)	D419E	possibly damaging	Het
Mroh2a	A	G	1: 88,186,386 (GRCm39)	S64G	probably benign	Het
Mroh2b	A	G	15: 4,938,463 (GRCm39)	K251E	possibly damaging	Het
Myh4	A	G	11: 67,142,644 (GRCm39)	E935G	probably damaging	Het
Nat8f2	C	A	6: 85,844,994 (GRCm39)	A123S	possibly damaging	Het
Niban1	A	G	1: 151,593,837 (GRCm39)	T841A	probably benign	Het
Or4d11	G	A	19: 12,013,192 (GRCm39)	L305F	probably benign	Het
Pcdha9	T	A	18: 37,131,156 (GRCm39)	V75E	probably damaging	Het
Pebp4	A	T	14: 70,200,991 (GRCm39)		probably null	Het
Pitx1	A	G	13: 55,974,166 (GRCm39)	S222P	probably benign	Het
Plekhg3	G	A	12: 76,625,174 (GRCm39)	V1339M	possibly damaging	Het
Plekhs1	C	T	19: 56,468,260 (GRCm39)	S276L	possibly damaging	Het
Plin4	T	C	17: 56,411,932 (GRCm39)	T700A	possibly damaging	Het
Plxnb2	T	C	15: 89,048,412 (GRCm39)		probably null	Het
Pms2	T	C	5: 143,864,943 (GRCm39)	I675T	probably damaging	Het
Polrmt	A	G	10: 79,577,888 (GRCm39)	L268P	probably damaging	Het
Rtp1	A	G	16: 23,248,025 (GRCm39)	T33A	probably benign	Het
Safb2	T	C	17: 56,882,346 (GRCm39)		probably benign	Het
Sdk1	C	A	5: 142,085,941 (GRCm39)	P1383Q	probably damaging	Het
Setdb1	A	T	3: 95,244,569 (GRCm39)	C758S	probably damaging	Het
Sh3gl2	T	C	4: 85,317,160 (GRCm39)		probably benign	Het
Slc13a2	G	A	11: 78,295,648 (GRCm39)		probably benign	Het
Slc35b1	T	C	11: 95,278,631 (GRCm39)	Y126H	probably damaging	Het
Strip2	C	A	6: 29,917,154 (GRCm39)		probably benign	Het
Tbx4	A	G	11: 85,805,230 (GRCm39)	T440A	probably damaging	Het
Tcf7l2	C	A	19: 55,907,940 (GRCm39)		probably null	Het
Tgfb1	A	C	7: 25,387,574 (GRCm39)	D94A	probably benign	Het
Tmem132b	T	C	5: 125,864,797 (GRCm39)	C968R	probably damaging	Het
Tmem176b	T	A	6: 48,811,467 (GRCm39)	M61L	probably benign	Het
Tmem258	A	G	19: 10,184,689 (GRCm39)		probably null	Het
Tpr	T	C	1: 150,302,639 (GRCm39)	L1379S	probably benign	Het
Vmn2r44	T	C	7: 8,383,123 (GRCm39)	D157G	possibly damaging	Het
Wfdc8	T	C	2: 164,439,649 (GRCm39)	I244M	probably benign	Het
Zfp341	T	C	2: 154,466,921 (GRCm39)	S97P	probably benign	Het
Zfp655	T	C	5: 145,180,445 (GRCm39)	V101A	probably benign	Het
Zfp788	T	C	7: 41,299,277 (GRCm39)	S586P	probably damaging	Het
Zfp874b	C	T	13: 67,629,373 (GRCm39)	V52I	possibly damaging	Het

Other mutations in Celsr1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00392:Celsr1	APN	15	85,815,546 (GRCm39)	missense	probably benign	0.04
IGL00519:Celsr1	APN	15	85,915,037 (GRCm39)	missense	probably damaging	1.00
IGL00909:Celsr1	APN	15	85,806,436 (GRCm39)	missense	probably damaging	1.00
IGL01303:Celsr1	APN	15	85,914,692 (GRCm39)	missense	probably damaging	0.97
IGL01726:Celsr1	APN	15	85,810,391 (GRCm39)	missense	probably benign	0.35
IGL01910:Celsr1	APN	15	85,814,096 (GRCm39)	missense	probably benign
IGL01931:Celsr1	APN	15	85,791,861 (GRCm39)	missense	probably damaging	1.00
IGL01952:Celsr1	APN	15	85,847,424 (GRCm39)	missense	probably benign	0.35
IGL02090:Celsr1	APN	15	85,791,922 (GRCm39)	missense	possibly damaging	0.49
IGL02191:Celsr1	APN	15	85,863,205 (GRCm39)	missense	possibly damaging	0.69
IGL02372:Celsr1	APN	15	85,814,108 (GRCm39)	missense	probably benign	0.01
IGL02413:Celsr1	APN	15	85,915,427 (GRCm39)	missense	possibly damaging	0.96
IGL02478:Celsr1	APN	15	85,825,337 (GRCm39)	missense	possibly damaging	0.68
IGL02507:Celsr1	APN	15	85,784,889 (GRCm39)	utr 3 prime	probably benign
IGL02508:Celsr1	APN	15	85,914,818 (GRCm39)	nonsense	probably null
IGL02899:Celsr1	APN	15	85,915,927 (GRCm39)	missense	probably damaging	0.98
IGL02939:Celsr1	APN	15	85,785,673 (GRCm39)	missense	probably benign
IGL03212:Celsr1	APN	15	85,814,878 (GRCm39)	missense	probably benign	0.04
P0028:Celsr1	UTSW	15	85,806,436 (GRCm39)	missense	probably damaging	1.00
PIT4305001:Celsr1	UTSW	15	85,785,138 (GRCm39)	missense	possibly damaging	0.87
PIT4480001:Celsr1	UTSW	15	85,916,615 (GRCm39)	missense	probably damaging	0.99
R0018:Celsr1	UTSW	15	85,915,243 (GRCm39)	missense	possibly damaging	0.47
R0018:Celsr1	UTSW	15	85,915,243 (GRCm39)	missense	possibly damaging	0.47
R0038:Celsr1	UTSW	15	85,813,620 (GRCm39)	missense	possibly damaging	0.65
R0057:Celsr1	UTSW	15	85,914,963 (GRCm39)	missense	probably benign	0.02
R0060:Celsr1	UTSW	15	85,806,399 (GRCm39)	missense	probably damaging	0.98
R0060:Celsr1	UTSW	15	85,806,399 (GRCm39)	missense	probably damaging	0.98
R0279:Celsr1	UTSW	15	85,787,065 (GRCm39)	missense	probably benign	0.00
R0570:Celsr1	UTSW	15	85,787,566 (GRCm39)	missense	probably benign	0.18
R0611:Celsr1	UTSW	15	85,816,524 (GRCm39)	missense	possibly damaging	0.91
R0731:Celsr1	UTSW	15	85,785,798 (GRCm39)	missense	probably benign
R0792:Celsr1	UTSW	15	85,815,477 (GRCm39)	missense	probably benign	0.02
R0943:Celsr1	UTSW	15	85,787,489 (GRCm39)	missense	probably damaging	1.00
R0989:Celsr1	UTSW	15	85,915,480 (GRCm39)	missense	probably benign	0.39
R1118:Celsr1	UTSW	15	85,916,248 (GRCm39)	missense	probably damaging	1.00
R1237:Celsr1	UTSW	15	85,788,175 (GRCm39)	missense	probably benign	0.01
R1239:Celsr1	UTSW	15	85,863,347 (GRCm39)	missense	probably damaging	0.99
R1405:Celsr1	UTSW	15	85,789,635 (GRCm39)	splice site	probably null
R1405:Celsr1	UTSW	15	85,789,635 (GRCm39)	splice site	probably null
R1522:Celsr1	UTSW	15	85,815,477 (GRCm39)	missense	probably benign	0.02
R1662:Celsr1	UTSW	15	85,915,263 (GRCm39)	missense	probably damaging	1.00
R1673:Celsr1	UTSW	15	85,816,658 (GRCm39)	missense	probably benign	0.00
R1795:Celsr1	UTSW	15	85,914,524 (GRCm39)	missense	probably damaging	0.99
R1799:Celsr1	UTSW	15	85,916,886 (GRCm39)	missense	probably damaging	1.00
R1858:Celsr1	UTSW	15	85,916,960 (GRCm39)	missense	probably damaging	1.00
R2040:Celsr1	UTSW	15	85,917,088 (GRCm39)	missense	probably damaging	1.00
R2050:Celsr1	UTSW	15	85,914,748 (GRCm39)	missense	probably benign	0.02
R2131:Celsr1	UTSW	15	85,847,424 (GRCm39)	missense	probably benign	0.35
R2132:Celsr1	UTSW	15	85,916,168 (GRCm39)	missense	possibly damaging	0.91
R2189:Celsr1	UTSW	15	85,863,431 (GRCm39)	missense	possibly damaging	0.93
R2192:Celsr1	UTSW	15	85,800,924 (GRCm39)	missense	possibly damaging	0.93
R4213:Celsr1	UTSW	15	85,916,008 (GRCm39)	missense	probably damaging	1.00
R4356:Celsr1	UTSW	15	85,863,028 (GRCm39)	missense	probably damaging	1.00
R4414:Celsr1	UTSW	15	85,812,200 (GRCm39)	missense	probably damaging	1.00
R4414:Celsr1	UTSW	15	85,847,334 (GRCm39)	missense	probably benign	0.00
R4416:Celsr1	UTSW	15	85,812,200 (GRCm39)	missense	probably damaging	1.00
R4645:Celsr1	UTSW	15	85,800,957 (GRCm39)	missense	probably benign	0.35
R4666:Celsr1	UTSW	15	85,914,695 (GRCm39)	missense	probably damaging	1.00
R4687:Celsr1	UTSW	15	85,816,661 (GRCm39)	missense	possibly damaging	0.94
R4735:Celsr1	UTSW	15	85,790,230 (GRCm39)	critical splice acceptor site	probably null
R4804:Celsr1	UTSW	15	85,822,154 (GRCm39)	missense	possibly damaging	0.49
R4995:Celsr1	UTSW	15	85,822,112 (GRCm39)	missense	probably damaging	0.99
R5070:Celsr1	UTSW	15	85,823,335 (GRCm39)	missense	possibly damaging	0.89
R5218:Celsr1	UTSW	15	85,816,585 (GRCm39)	missense	probably damaging	1.00
R5280:Celsr1	UTSW	15	85,814,747 (GRCm39)	missense	probably benign
R5310:Celsr1	UTSW	15	85,810,423 (GRCm39)	missense	possibly damaging	0.88
R5388:Celsr1	UTSW	15	85,809,719 (GRCm39)	missense	probably damaging	0.99
R5639:Celsr1	UTSW	15	85,914,968 (GRCm39)	missense	probably damaging	1.00
R5758:Celsr1	UTSW	15	85,825,465 (GRCm39)	missense	probably benign	0.27
R5778:Celsr1	UTSW	15	85,917,156 (GRCm39)	missense	probably damaging	1.00
R5893:Celsr1	UTSW	15	85,788,215 (GRCm39)	missense	probably benign	0.02
R5915:Celsr1	UTSW	15	85,914,550 (GRCm39)	missense	probably damaging	0.96
R5915:Celsr1	UTSW	15	85,822,176 (GRCm39)	missense	probably benign
R5932:Celsr1	UTSW	15	85,916,905 (GRCm39)	missense	probably damaging	1.00
R5950:Celsr1	UTSW	15	85,916,701 (GRCm39)	missense	probably damaging	1.00
R5975:Celsr1	UTSW	15	85,803,239 (GRCm39)	splice site	probably null
R6050:Celsr1	UTSW	15	85,814,812 (GRCm39)	missense	probably benign	0.00
R6117:Celsr1	UTSW	15	85,816,612 (GRCm39)	missense	probably benign	0.04
R6178:Celsr1	UTSW	15	85,785,222 (GRCm39)	missense	probably benign	0.08
R6186:Celsr1	UTSW	15	85,805,394 (GRCm39)	missense	possibly damaging	0.84
R6212:Celsr1	UTSW	15	85,800,888 (GRCm39)	missense	probably benign	0.25
R6307:Celsr1	UTSW	15	85,812,531 (GRCm39)	missense	probably benign
R6320:Celsr1	UTSW	15	85,785,160 (GRCm39)	missense	probably benign	0.13
R6349:Celsr1	UTSW	15	85,915,885 (GRCm39)	missense	probably damaging	1.00
R6478:Celsr1	UTSW	15	85,809,719 (GRCm39)	missense	probably damaging	0.99
R6504:Celsr1	UTSW	15	85,863,121 (GRCm39)	missense	probably benign	0.07
R6607:Celsr1	UTSW	15	85,847,486 (GRCm39)	missense	probably benign
R6615:Celsr1	UTSW	15	85,786,315 (GRCm39)	critical splice donor site	probably null
R6661:Celsr1	UTSW	15	85,803,135 (GRCm39)	missense	probably damaging	1.00
R6722:Celsr1	UTSW	15	85,790,115 (GRCm39)	critical splice donor site	probably null
R6743:Celsr1	UTSW	15	85,791,799 (GRCm39)	missense	probably damaging	0.96
R6746:Celsr1	UTSW	15	85,915,696 (GRCm39)	missense	probably damaging	1.00
R6772:Celsr1	UTSW	15	85,914,983 (GRCm39)	missense	probably benign
R6838:Celsr1	UTSW	15	85,823,395 (GRCm39)	missense	probably benign
R6886:Celsr1	UTSW	15	85,915,855 (GRCm39)	missense	probably benign	0.00
R7030:Celsr1	UTSW	15	85,789,679 (GRCm39)	missense	probably damaging	0.99
R7060:Celsr1	UTSW	15	85,916,856 (GRCm39)	missense	probably benign	0.07
R7080:Celsr1	UTSW	15	85,816,652 (GRCm39)	missense	possibly damaging	0.87
R7325:Celsr1	UTSW	15	85,917,209 (GRCm39)	missense	probably damaging	0.99
R7357:Celsr1	UTSW	15	85,914,715 (GRCm39)	missense	probably benign	0.00
R7371:Celsr1	UTSW	15	85,914,875 (GRCm39)	missense	possibly damaging	0.91
R7446:Celsr1	UTSW	15	85,791,874 (GRCm39)	missense	possibly damaging	0.95
R7465:Celsr1	UTSW	15	85,917,593 (GRCm39)	missense	probably benign
R7491:Celsr1	UTSW	15	85,916,719 (GRCm39)	missense	possibly damaging	0.78
R7639:Celsr1	UTSW	15	85,814,073 (GRCm39)	missense	probably benign	0.00
R7685:Celsr1	UTSW	15	85,862,933 (GRCm39)	nonsense	probably null
R7741:Celsr1	UTSW	15	85,863,303 (GRCm39)	missense	possibly damaging	0.94
R7768:Celsr1	UTSW	15	85,816,610 (GRCm39)	missense	probably benign
R7974:Celsr1	UTSW	15	85,915,231 (GRCm39)	missense	probably damaging	1.00
R7977:Celsr1	UTSW	15	85,917,194 (GRCm39)	missense	probably damaging	1.00
R7987:Celsr1	UTSW	15	85,917,194 (GRCm39)	missense	probably damaging	1.00
R8073:Celsr1	UTSW	15	85,823,356 (GRCm39)	missense	probably benign	0.00
R8099:Celsr1	UTSW	15	85,915,801 (GRCm39)	missense	probably damaging	0.99
R8190:Celsr1	UTSW	15	85,787,090 (GRCm39)	missense	probably damaging	0.99
R8210:Celsr1	UTSW	15	85,863,436 (GRCm39)	missense	probably benign	0.00
R8289:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8290:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8292:Celsr1	UTSW	15	85,791,819 (GRCm39)	missense	possibly damaging	0.90
R8328:Celsr1	UTSW	15	85,806,445 (GRCm39)	missense	probably benign	0.00
R8330:Celsr1	UTSW	15	85,816,501 (GRCm39)	missense	probably damaging	0.99
R8333:Celsr1	UTSW	15	85,915,615 (GRCm39)	missense	possibly damaging	0.65
R8352:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8384:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8452:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8463:Celsr1	UTSW	15	85,914,415 (GRCm39)	missense	probably damaging	1.00
R8479:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8480:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8493:Celsr1	UTSW	15	85,822,207 (GRCm39)	missense	possibly damaging	0.67
R8498:Celsr1	UTSW	15	85,823,306 (GRCm39)	missense	probably benign	0.01
R8506:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8771:Celsr1	UTSW	15	85,788,175 (GRCm39)	missense	probably benign	0.01
R8891:Celsr1	UTSW	15	85,822,194 (GRCm39)	missense	probably benign	0.01
R8905:Celsr1	UTSW	15	85,788,269 (GRCm39)	intron	probably benign
R8924:Celsr1	UTSW	15	85,916,671 (GRCm39)	missense	possibly damaging	0.94
R8979:Celsr1	UTSW	15	85,847,340 (GRCm39)	missense	probably damaging	0.96
R9069:Celsr1	UTSW	15	85,914,772 (GRCm39)	missense	possibly damaging	0.53
R9115:Celsr1	UTSW	15	85,803,217 (GRCm39)	missense	probably damaging	1.00
R9194:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9196:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9198:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9200:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9201:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9202:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9203:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9222:Celsr1	UTSW	15	85,815,471 (GRCm39)	missense	possibly damaging	0.68
R9236:Celsr1	UTSW	15	85,915,051 (GRCm39)	missense	probably damaging	1.00
R9384:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9386:Celsr1	UTSW	15	85,863,231 (GRCm39)	missense	probably damaging	1.00
R9400:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9401:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9415:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9428:Celsr1	UTSW	15	85,815,549 (GRCm39)	missense	possibly damaging	0.64
R9435:Celsr1	UTSW	15	85,806,535 (GRCm39)	splice site	probably benign
R9493:Celsr1	UTSW	15	85,785,346 (GRCm39)	missense	probably damaging	0.98
R9495:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9499:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9607:Celsr1	UTSW	15	85,915,229 (GRCm39)	missense
R9673:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
Z1176:Celsr1	UTSW	15	85,847,301 (GRCm39)	missense	probably damaging	0.96
Z1177:Celsr1	UTSW	15	85,863,052 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTACACATGAGTTAAGAGTCTGGG -3'
(R):5'- CCTTCCATCAGCCAAGTGTG -3'

Sequencing Primer
(F):5'- GGATGCCTACAAGATGGACCATTAC -3'
(R):5'- TCCATCAGCCAAGTGTGAAGGTC -3'

Posted On

2016-10-05