Incidental Mutation 'R5503:Mon2'
| ID |
430750 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mon2
|
| Ensembl Gene |
ENSMUSG00000034602 |
| Gene Name |
MON2 homolog, regulator of endosome to Golgi trafficking |
| Synonyms |
2610528O22Rik, SF21 |
| MMRRC Submission |
043064-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.909)
|
| Stock # |
R5503 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
122992060-123076505 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 123032645 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 501
(M501K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131052
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037557]
[ENSMUST00000073792]
[ENSMUST00000170935]
[ENSMUST00000219203]
|
| AlphaFold |
Q80TL7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000037557
AA Change: M501K
PolyPhen 2
Score 0.535 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000037568
Gene: ENSMUSG00000034602
AA Change: M501K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
119 |
138 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
176 |
N/A |
INTRINSIC |
|
Pfam:Sec7_N
|
208 |
294 |
6.5e-16 |
PFAM |
|
Pfam:Sec7_N
|
299 |
385 |
2.6e-16 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
575 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
627 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
844 |
929 |
2.4e-21 |
PFAM |
|
low complexity region
|
984 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1182 |
1193 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000073792
AA Change: M501K
PolyPhen 2
Score 0.535 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000073462
Gene: ENSMUSG00000034602
AA Change: M501K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DCB
|
8 |
184 |
3e-72 |
PFAM |
|
Pfam:Sec7_N
|
211 |
384 |
3.1e-58 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
575 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
627 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
848 |
929 |
6.6e-20 |
PFAM |
|
Pfam:Mon2_C
|
932 |
1706 |
N/A |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000170935
AA Change: M501K
PolyPhen 2
Score 0.535 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000131052
Gene: ENSMUSG00000034602
AA Change: M501K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
119 |
138 |
N/A |
INTRINSIC |
|
low complexity region
|
164 |
176 |
N/A |
INTRINSIC |
|
Pfam:Sec7_N
|
208 |
294 |
6.5e-16 |
PFAM |
|
Pfam:Sec7_N
|
299 |
385 |
2.6e-16 |
PFAM |
|
low complexity region
|
405 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
559 |
576 |
N/A |
INTRINSIC |
|
low complexity region
|
616 |
628 |
N/A |
INTRINSIC |
|
Pfam:DUF1981
|
845 |
930 |
8.1e-22 |
PFAM |
|
low complexity region
|
985 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1183 |
1194 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218253
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219001
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000219203
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222536
|
| Meta Mutation Damage Score |
0.2316 |
| Coding Region Coverage |
- 1x: 98.3%
- 3x: 97.4%
- 10x: 95.4%
- 20x: 91.5%
|
| Validation Efficiency |
96% (103/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
G |
T |
12: 71,164,546 (GRCm38) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,164,547 (GRCm38) |
E685V |
possibly damaging |
Het |
| Abca6 |
A |
G |
11: 110,218,257 (GRCm38) |
S696P |
probably damaging |
Het |
| Abca9 |
G |
A |
11: 110,141,610 (GRCm38) |
T727M |
probably damaging |
Het |
| Alpk2 |
T |
C |
18: 65,306,241 (GRCm38) |
R1161G |
probably benign |
Het |
| Amy1 |
T |
C |
3: 113,556,060 (GRCm38) |
D487G |
probably benign |
Het |
| Arap2 |
G |
A |
5: 62,630,186 (GRCm38) |
A1409V |
probably damaging |
Het |
| B020004J07Rik |
A |
T |
4: 101,835,802 (GRCm38) |
Y334N |
probably benign |
Het |
| B4galt6 |
C |
A |
18: 20,745,352 (GRCm38) |
|
probably null |
Het |
| Cacna1s |
G |
A |
1: 136,086,742 (GRCm38) |
G382D |
probably damaging |
Het |
| Camk2a |
A |
G |
18: 60,978,000 (GRCm38) |
D87G |
probably damaging |
Het |
| Cdh18 |
A |
G |
15: 23,436,534 (GRCm38) |
Y492C |
probably damaging |
Het |
| Col18a1 |
C |
T |
10: 77,071,620 (GRCm38) |
G861D |
probably damaging |
Het |
| Col4a3bp |
C |
T |
13: 96,543,239 (GRCm38) |
R26C |
possibly damaging |
Het |
| Crybg1 |
C |
A |
10: 43,998,766 (GRCm38) |
S782I |
probably benign |
Het |
| Csgalnact1 |
G |
A |
8: 68,461,473 (GRCm38) |
L27F |
probably damaging |
Het |
| Dab1 |
T |
A |
4: 104,512,264 (GRCm38) |
C3S |
probably benign |
Het |
| Dapk1 |
T |
C |
13: 60,725,312 (GRCm38) |
F343L |
probably benign |
Het |
| Dgat1 |
A |
T |
15: 76,502,194 (GRCm38) |
|
probably benign |
Het |
| Dnah11 |
C |
A |
12: 117,880,451 (GRCm38) |
|
probably null |
Het |
| Dsg2 |
T |
A |
18: 20,580,651 (GRCm38) |
Y226* |
probably null |
Het |
| Epg5 |
T |
A |
18: 77,951,207 (GRCm38) |
M351K |
possibly damaging |
Het |
| F13b |
A |
G |
1: 139,522,543 (GRCm38) |
T648A |
probably benign |
Het |
| Fgf17 |
T |
C |
14: 70,636,968 (GRCm38) |
Y127C |
probably damaging |
Het |
| Fkbp15 |
G |
A |
4: 62,327,887 (GRCm38) |
P435S |
probably benign |
Het |
| Gfm1 |
G |
A |
3: 67,453,727 (GRCm38) |
|
probably null |
Het |
| Gigyf1 |
T |
C |
5: 137,523,467 (GRCm38) |
|
probably benign |
Het |
| Gm12830 |
A |
T |
4: 114,821,739 (GRCm38) |
T6S |
unknown |
Het |
| Gm6465 |
A |
T |
5: 11,848,183 (GRCm38) |
N88I |
probably damaging |
Het |
| Gpr18 |
C |
T |
14: 121,911,747 (GRCm38) |
V289I |
probably damaging |
Het |
| Ipp |
G |
T |
4: 116,537,938 (GRCm38) |
E557* |
probably null |
Het |
| Klhl12 |
T |
A |
1: 134,485,915 (GRCm38) |
|
probably null |
Het |
| Klhl38 |
A |
G |
15: 58,322,349 (GRCm38) |
V328A |
possibly damaging |
Het |
| Kndc1 |
A |
G |
7: 139,931,889 (GRCm38) |
T1470A |
probably damaging |
Het |
| Kntc1 |
T |
A |
5: 123,819,876 (GRCm38) |
D2173E |
possibly damaging |
Het |
| Lipi |
T |
C |
16: 75,573,976 (GRCm38) |
K118E |
probably benign |
Het |
| Marf1 |
A |
C |
16: 14,152,231 (GRCm38) |
L208R |
probably damaging |
Het |
| Misp |
G |
A |
10: 79,826,718 (GRCm38) |
R323K |
probably damaging |
Het |
| Mlxip |
T |
A |
5: 123,395,327 (GRCm38) |
M133K |
probably damaging |
Het |
| Myh2 |
A |
G |
11: 67,173,449 (GRCm38) |
I77V |
probably benign |
Het |
| Napa |
C |
A |
7: 16,115,624 (GRCm38) |
Q254K |
probably benign |
Het |
| Nckap5l |
C |
A |
15: 99,425,622 (GRCm38) |
G1000V |
probably damaging |
Het |
| Neo1 |
A |
T |
9: 58,985,650 (GRCm38) |
S236R |
possibly damaging |
Het |
| Neurl4 |
T |
A |
11: 69,906,368 (GRCm38) |
Y594N |
probably damaging |
Het |
| Nmral1 |
G |
A |
16: 4,715,629 (GRCm38) |
P94L |
probably benign |
Het |
| Notch3 |
A |
T |
17: 32,147,055 (GRCm38) |
I1024N |
probably benign |
Het |
| Nsd1 |
T |
A |
13: 55,245,939 (GRCm38) |
I451K |
probably damaging |
Het |
| Nt5c3b |
T |
C |
11: 100,433,057 (GRCm38) |
D143G |
probably benign |
Het |
| Olfr1415 |
C |
A |
1: 92,491,196 (GRCm38) |
K186N |
probably benign |
Het |
| Olfr27 |
A |
G |
9: 39,144,484 (GRCm38) |
N128S |
probably benign |
Het |
| Olfr316 |
T |
A |
11: 58,758,328 (GRCm38) |
V221E |
probably damaging |
Het |
| Olfr45 |
A |
C |
7: 140,691,396 (GRCm38) |
M164L |
probably benign |
Het |
| Olfr77 |
A |
G |
9: 19,920,379 (GRCm38) |
T57A |
probably benign |
Het |
| Olfr912 |
T |
C |
9: 38,582,072 (GRCm38) |
V265A |
probably benign |
Het |
| Oplah |
A |
G |
15: 76,305,446 (GRCm38) |
|
probably null |
Het |
| Phb2 |
T |
A |
6: 124,713,022 (GRCm38) |
|
probably benign |
Het |
| Plcl2 |
A |
G |
17: 50,509,929 (GRCm38) |
I108V |
probably benign |
Het |
| Plpp6 |
T |
A |
19: 28,964,746 (GRCm38) |
M249K |
probably damaging |
Het |
| Pnpt1 |
G |
A |
11: 29,138,156 (GRCm38) |
G189E |
probably damaging |
Het |
| Ptprn |
C |
T |
1: 75,251,875 (GRCm38) |
V853M |
probably damaging |
Het |
| Ptprq |
T |
C |
10: 107,688,328 (GRCm38) |
|
probably null |
Het |
| Rai1 |
G |
A |
11: 60,186,453 (GRCm38) |
V448I |
probably benign |
Het |
| Rbm20 |
T |
A |
19: 53,851,354 (GRCm38) |
C925S |
possibly damaging |
Het |
| Rin3 |
C |
A |
12: 102,313,055 (GRCm38) |
P41Q |
probably benign |
Het |
| Rpl31-ps21 |
T |
C |
5: 21,119,507 (GRCm38) |
|
noncoding transcript |
Het |
| Rpl39-ps |
A |
T |
15: 102,635,126 (GRCm38) |
|
noncoding transcript |
Het |
| Rtn4ip1 |
T |
A |
10: 43,907,883 (GRCm38) |
D133E |
probably benign |
Het |
| Ryr1 |
T |
C |
7: 29,069,028 (GRCm38) |
K2839E |
possibly damaging |
Het |
| Sept5 |
T |
C |
16: 18,623,368 (GRCm38) |
K268R |
probably benign |
Het |
| Serpinb6b |
T |
A |
13: 32,977,659 (GRCm38) |
D238E |
possibly damaging |
Het |
| Slc15a2 |
C |
T |
16: 36,762,385 (GRCm38) |
V214M |
probably damaging |
Het |
| Smarca2 |
T |
C |
19: 26,623,936 (GRCm38) |
M18T |
probably damaging |
Het |
| Smarca2 |
C |
A |
19: 26,682,046 (GRCm38) |
T912K |
possibly damaging |
Het |
| Smdt1 |
A |
T |
15: 82,347,900 (GRCm38) |
R46S |
possibly damaging |
Het |
| Spa17 |
A |
C |
9: 37,611,977 (GRCm38) |
F5V |
probably damaging |
Het |
| Spag17 |
A |
G |
3: 100,027,244 (GRCm38) |
E614G |
possibly damaging |
Het |
| Sstr4 |
CGAGGAGGAGGAGGA |
CGAGGAGGAGGAGGAGGA |
2: 148,395,551 (GRCm38) |
|
probably benign |
Het |
| Tlr1 |
A |
T |
5: 64,926,292 (GRCm38) |
V314D |
probably damaging |
Het |
| Trappc8 |
A |
T |
18: 20,836,900 (GRCm38) |
L1011Q |
probably benign |
Het |
| Tsga10 |
A |
G |
1: 37,760,947 (GRCm38) |
*691Q |
probably null |
Het |
| Vav1 |
A |
T |
17: 57,303,079 (GRCm38) |
K420* |
probably null |
Het |
| Vmn1r174 |
C |
G |
7: 23,754,137 (GRCm38) |
T76R |
probably benign |
Het |
| Vmn2r116 |
A |
G |
17: 23,386,804 (GRCm38) |
E230G |
probably benign |
Het |
| Vps13b |
A |
G |
15: 35,452,166 (GRCm38) |
T637A |
probably damaging |
Het |
| Zbtb7a |
A |
G |
10: 81,144,797 (GRCm38) |
E275G |
probably damaging |
Het |
| Zfp280b |
A |
G |
10: 76,039,462 (GRCm38) |
|
probably null |
Het |
| Zfp763 |
A |
G |
17: 33,019,533 (GRCm38) |
Y213H |
possibly damaging |
Het |
| Zfp78 |
T |
A |
7: 6,378,529 (GRCm38) |
W161R |
probably benign |
Het |
|
| Other mutations in Mon2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Mon2
|
APN |
10 |
123,026,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Mon2
|
APN |
10 |
123,010,539 (GRCm38) |
nonsense |
probably null |
|
|
IGL02080:Mon2
|
APN |
10 |
123,052,190 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02157:Mon2
|
APN |
10 |
123,013,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02419:Mon2
|
APN |
10 |
123,016,447 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL02498:Mon2
|
APN |
10 |
123,034,330 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02638:Mon2
|
APN |
10 |
123,023,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02664:Mon2
|
APN |
10 |
123,009,496 (GRCm38) |
splice site |
probably benign |
|
|
IGL02690:Mon2
|
APN |
10 |
123,009,627 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
IGL02878:Mon2
|
APN |
10 |
123,006,991 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL03092:Mon2
|
APN |
10 |
123,018,100 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03103:Mon2
|
APN |
10 |
123,030,103 (GRCm38) |
splice site |
probably benign |
|
|
IGL03208:Mon2
|
APN |
10 |
123,018,069 (GRCm38) |
splice site |
probably benign |
|
|
R0010:Mon2
|
UTSW |
10 |
123,032,694 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0016:Mon2
|
UTSW |
10 |
123,035,546 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0016:Mon2
|
UTSW |
10 |
123,035,546 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0027:Mon2
|
UTSW |
10 |
123,036,048 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R0027:Mon2
|
UTSW |
10 |
123,036,048 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R0145:Mon2
|
UTSW |
10 |
123,013,512 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R0390:Mon2
|
UTSW |
10 |
123,007,021 (GRCm38) |
missense |
probably null |
0.05 |
|
R0481:Mon2
|
UTSW |
10 |
123,013,396 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R0513:Mon2
|
UTSW |
10 |
123,038,610 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0599:Mon2
|
UTSW |
10 |
123,026,065 (GRCm38) |
splice site |
probably benign |
|
|
R1226:Mon2
|
UTSW |
10 |
123,002,819 (GRCm38) |
missense |
probably benign |
0.17 |
|
R1548:Mon2
|
UTSW |
10 |
123,036,007 (GRCm38) |
splice site |
probably benign |
|
|
R1598:Mon2
|
UTSW |
10 |
123,016,396 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1650:Mon2
|
UTSW |
10 |
122,995,777 (GRCm38) |
missense |
probably benign |
0.45 |
|
R1687:Mon2
|
UTSW |
10 |
123,026,124 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1721:Mon2
|
UTSW |
10 |
123,031,097 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1768:Mon2
|
UTSW |
10 |
123,013,763 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1827:Mon2
|
UTSW |
10 |
123,046,311 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1879:Mon2
|
UTSW |
10 |
123,002,885 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Mon2
|
UTSW |
10 |
123,038,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1955:Mon2
|
UTSW |
10 |
123,038,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1968:Mon2
|
UTSW |
10 |
123,009,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2060:Mon2
|
UTSW |
10 |
122,995,776 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2160:Mon2
|
UTSW |
10 |
123,075,929 (GRCm38) |
nonsense |
probably null |
|
|
R2165:Mon2
|
UTSW |
10 |
123,042,364 (GRCm38) |
splice site |
probably null |
|
|
R3737:Mon2
|
UTSW |
10 |
123,013,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3814:Mon2
|
UTSW |
10 |
123,013,565 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4058:Mon2
|
UTSW |
10 |
123,002,819 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4091:Mon2
|
UTSW |
10 |
123,038,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4214:Mon2
|
UTSW |
10 |
123,016,492 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4354:Mon2
|
UTSW |
10 |
123,026,983 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4422:Mon2
|
UTSW |
10 |
123,042,982 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4505:Mon2
|
UTSW |
10 |
123,009,589 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4791:Mon2
|
UTSW |
10 |
123,006,057 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4797:Mon2
|
UTSW |
10 |
123,016,517 (GRCm38) |
missense |
probably benign |
0.45 |
|
R4944:Mon2
|
UTSW |
10 |
123,038,459 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4982:Mon2
|
UTSW |
10 |
122,995,789 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5298:Mon2
|
UTSW |
10 |
123,010,606 (GRCm38) |
missense |
probably benign |
|
|
R5653:Mon2
|
UTSW |
10 |
123,026,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5687:Mon2
|
UTSW |
10 |
123,008,239 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5838:Mon2
|
UTSW |
10 |
123,010,492 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6108:Mon2
|
UTSW |
10 |
123,032,695 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6182:Mon2
|
UTSW |
10 |
123,038,659 (GRCm38) |
splice site |
probably null |
|
|
R6355:Mon2
|
UTSW |
10 |
123,022,920 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R6358:Mon2
|
UTSW |
10 |
123,013,504 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6548:Mon2
|
UTSW |
10 |
123,036,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6557:Mon2
|
UTSW |
10 |
123,016,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6649:Mon2
|
UTSW |
10 |
123,038,480 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7140:Mon2
|
UTSW |
10 |
123,035,453 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7303:Mon2
|
UTSW |
10 |
123,038,459 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7317:Mon2
|
UTSW |
10 |
123,013,946 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7355:Mon2
|
UTSW |
10 |
123,009,516 (GRCm38) |
missense |
probably benign |
|
|
R7508:Mon2
|
UTSW |
10 |
123,023,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7509:Mon2
|
UTSW |
10 |
123,032,552 (GRCm38) |
missense |
probably benign |
|
|
R7647:Mon2
|
UTSW |
10 |
123,006,026 (GRCm38) |
missense |
probably benign |
|
|
R7720:Mon2
|
UTSW |
10 |
123,032,588 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7799:Mon2
|
UTSW |
10 |
123,042,331 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7801:Mon2
|
UTSW |
10 |
123,059,186 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7823:Mon2
|
UTSW |
10 |
123,032,654 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7985:Mon2
|
UTSW |
10 |
123,016,308 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8310:Mon2
|
UTSW |
10 |
123,002,783 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8810:Mon2
|
UTSW |
10 |
123,009,611 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R8825:Mon2
|
UTSW |
10 |
123,013,871 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8937:Mon2
|
UTSW |
10 |
123,059,205 (GRCm38) |
missense |
probably benign |
|
|
R8978:Mon2
|
UTSW |
10 |
123,035,564 (GRCm38) |
nonsense |
probably null |
|
|
R9011:Mon2
|
UTSW |
10 |
123,026,308 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9213:Mon2
|
UTSW |
10 |
123,036,111 (GRCm38) |
nonsense |
probably null |
|
|
R9358:Mon2
|
UTSW |
10 |
123,032,547 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9630:Mon2
|
UTSW |
10 |
123,038,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0022:Mon2
|
UTSW |
10 |
123,006,102 (GRCm38) |
missense |
probably benign |
0.07 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCAGCATGGTGATGTGTCAG -3'
(R):5'- GAGTCTACAAATTATGGGAATGCTTTC -3'
Sequencing Primer
(F):5'- ATGTGTCAGTATCAGGGACACTCC -3'
(R):5'- GGAATGCTTTCCTGTGGTTCTTTCC -3'
|
| Posted On |
2016-10-05 |
Incidental Mutation