Incidental Mutation 'R0479:Clca3a2'
| ID |
43252 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clca3a2
|
| Ensembl Gene |
ENSMUSG00000028262 |
| Gene Name |
chloride channel accessory 3A2 |
| Synonyms |
Clca2 |
| MMRRC Submission |
038679-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.097)
|
| Stock # |
R0479 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
3 |
| Chromosomal Location |
144502320-144525255 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 144796610 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Alanine
at position 199
(D199A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143161
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040465]
[ENSMUST00000198993]
|
| AlphaFold |
Q9EQR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040465
AA Change: D199A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000036029
Gene: ENSMUSG00000036960
AA Change: D199A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
29 |
N/A |
INTRINSIC |
|
VWA
|
309 |
485 |
3.55e-5 |
SMART |
|
low complexity region
|
739 |
754 |
N/A |
INTRINSIC |
|
Blast:FN3
|
765 |
875 |
5e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000198993
AA Change: D199A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000143161
Gene: ENSMUSG00000036960
AA Change: D199A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:CLCA_N
|
7 |
265 |
1.7e-121 |
PFAM |
|
VWA
|
309 |
485 |
2.2e-7 |
SMART |
|
Pfam:DUF1973
|
494 |
674 |
7.8e-75 |
PFAM |
|
| Meta Mutation Damage Score |
0.1271 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.6%
|
| Validation Efficiency |
98% (105/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ackr1 |
A |
G |
1: 173,159,712 (GRCm39) |
V269A |
probably benign |
Het |
| Acsl1 |
G |
A |
8: 46,984,109 (GRCm39) |
G543R |
probably damaging |
Het |
| Adam18 |
T |
C |
8: 25,141,838 (GRCm39) |
N244D |
probably benign |
Het |
| Adgra3 |
C |
T |
5: 50,147,607 (GRCm39) |
V478M |
probably benign |
Het |
| Arhgap39 |
C |
T |
15: 76,619,086 (GRCm39) |
D833N |
probably damaging |
Het |
| Arhgef10 |
A |
T |
8: 15,041,070 (GRCm39) |
E723V |
probably damaging |
Het |
| Arid3a |
C |
A |
10: 79,787,128 (GRCm39) |
N519K |
possibly damaging |
Het |
| Atrn |
T |
A |
2: 130,841,085 (GRCm39) |
Y1162* |
probably null |
Het |
| Cacng5 |
T |
A |
11: 107,768,777 (GRCm39) |
N172Y |
probably benign |
Het |
| Cct8 |
C |
T |
16: 87,284,594 (GRCm39) |
V198M |
probably damaging |
Het |
| Cep192 |
G |
A |
18: 67,991,089 (GRCm39) |
S1857N |
probably damaging |
Het |
| Cherp |
A |
T |
8: 73,216,991 (GRCm39) |
D657E |
possibly damaging |
Het |
| Cops7b |
A |
G |
1: 86,532,798 (GRCm39) |
T219A |
probably benign |
Het |
| Crb1 |
C |
T |
1: 139,126,352 (GRCm39) |
M1392I |
probably damaging |
Het |
| Csf3r |
A |
C |
4: 125,937,616 (GRCm39) |
E833D |
probably damaging |
Het |
| Cutc |
A |
G |
19: 43,756,655 (GRCm39) |
E247G |
probably damaging |
Het |
| Cyp2c38 |
A |
G |
19: 39,451,449 (GRCm39) |
L17P |
probably damaging |
Het |
| D5Ertd615e |
T |
A |
5: 45,320,796 (GRCm39) |
|
noncoding transcript |
Het |
| Ddx60 |
G |
T |
8: 62,422,691 (GRCm39) |
G643W |
probably damaging |
Het |
| Depdc1a |
C |
T |
3: 159,226,497 (GRCm39) |
T268I |
probably damaging |
Het |
| Dgke |
T |
C |
11: 88,943,296 (GRCm39) |
E231G |
probably benign |
Het |
| Dhrs7b |
T |
A |
11: 60,746,513 (GRCm39) |
|
probably benign |
Het |
| Dll3 |
A |
G |
7: 28,000,974 (GRCm39) |
V27A |
probably damaging |
Het |
| Dnmt3c |
T |
A |
2: 153,556,861 (GRCm39) |
|
probably null |
Het |
| Duox1 |
T |
C |
2: 122,176,861 (GRCm39) |
F1461L |
probably damaging |
Het |
| Enpep |
A |
G |
3: 129,106,323 (GRCm39) |
V301A |
possibly damaging |
Het |
| Eny2 |
T |
A |
15: 44,299,000 (GRCm39) |
|
probably null |
Het |
| Esr1 |
A |
G |
10: 4,947,911 (GRCm39) |
D488G |
probably damaging |
Het |
| Ets1 |
A |
G |
9: 32,641,476 (GRCm39) |
K110E |
probably damaging |
Het |
| Eya2 |
T |
A |
2: 165,557,876 (GRCm39) |
Y157* |
probably null |
Het |
| F830045P16Rik |
T |
G |
2: 129,314,608 (GRCm39) |
D223A |
possibly damaging |
Het |
| Fbh1 |
A |
G |
2: 11,763,230 (GRCm39) |
Y475H |
probably damaging |
Het |
| Fbxo39 |
T |
C |
11: 72,208,419 (GRCm39) |
I257T |
probably damaging |
Het |
| Fkbp10 |
T |
C |
11: 100,306,740 (GRCm39) |
V23A |
probably damaging |
Het |
| Foxp3 |
A |
G |
X: 7,453,583 (GRCm39) |
I128V |
possibly damaging |
Het |
| Fzd7 |
T |
C |
1: 59,522,867 (GRCm39) |
F250S |
probably damaging |
Het |
| Gaa |
A |
G |
11: 119,172,062 (GRCm39) |
T722A |
possibly damaging |
Het |
| Gemin5 |
A |
G |
11: 58,030,377 (GRCm39) |
V816A |
probably benign |
Het |
| Glb1l3 |
T |
A |
9: 26,740,389 (GRCm39) |
T314S |
probably benign |
Het |
| H2-Ab1 |
A |
G |
17: 34,483,942 (GRCm39) |
E101G |
possibly damaging |
Het |
| Hydin |
A |
C |
8: 111,325,720 (GRCm39) |
T4710P |
probably damaging |
Het |
| Ica1 |
C |
T |
6: 8,754,627 (GRCm39) |
V48M |
probably damaging |
Het |
| Ica1 |
T |
C |
6: 8,754,683 (GRCm39) |
Y29C |
probably damaging |
Het |
| Ints7 |
T |
A |
1: 191,346,666 (GRCm39) |
|
probably null |
Het |
| Iqub |
T |
C |
6: 24,505,809 (GRCm39) |
E33G |
probably benign |
Het |
| Itgb1bp2 |
T |
A |
X: 100,492,806 (GRCm39) |
C10S |
probably damaging |
Het |
| Katnip |
T |
C |
7: 125,442,518 (GRCm39) |
L809S |
probably benign |
Het |
| Kcnd1 |
T |
A |
X: 7,697,461 (GRCm39) |
I391N |
possibly damaging |
Het |
| Kdm8 |
T |
C |
7: 125,051,812 (GRCm39) |
L135P |
probably damaging |
Het |
| Ksr1 |
T |
C |
11: 78,916,109 (GRCm39) |
D574G |
probably damaging |
Het |
| Lama5 |
C |
T |
2: 179,826,250 (GRCm39) |
R2331H |
probably benign |
Het |
| Larp1 |
C |
A |
11: 57,933,646 (GRCm39) |
N357K |
possibly damaging |
Het |
| Lgi3 |
C |
T |
14: 70,771,992 (GRCm39) |
|
probably benign |
Het |
| Lmbrd1 |
T |
A |
1: 24,785,878 (GRCm39) |
|
probably benign |
Het |
| Methig1 |
A |
T |
15: 100,272,825 (GRCm39) |
K53* |
probably null |
Het |
| Mfap3 |
T |
A |
11: 57,420,469 (GRCm39) |
I150N |
probably damaging |
Het |
| Mug1 |
A |
T |
6: 121,817,186 (GRCm39) |
Q85L |
probably benign |
Het |
| Npl |
A |
G |
1: 153,391,155 (GRCm39) |
V200A |
probably damaging |
Het |
| Nuf2 |
A |
T |
1: 169,326,503 (GRCm39) |
|
probably benign |
Het |
| Obscn |
A |
G |
11: 59,003,533 (GRCm39) |
V1255A |
probably damaging |
Het |
| Or2z8 |
C |
T |
8: 72,812,244 (GRCm39) |
T240M |
probably damaging |
Het |
| Or5h18 |
C |
T |
16: 58,847,491 (GRCm39) |
V260M |
possibly damaging |
Het |
| Or8b51 |
T |
C |
9: 38,569,478 (GRCm39) |
D70G |
probably damaging |
Het |
| P2rx1 |
T |
C |
11: 72,903,787 (GRCm39) |
V283A |
probably damaging |
Het |
| Pex2 |
C |
A |
3: 5,626,355 (GRCm39) |
L151F |
probably damaging |
Het |
| Pias1 |
A |
G |
9: 62,800,400 (GRCm39) |
|
probably benign |
Het |
| Pmfbp1 |
A |
T |
8: 110,257,105 (GRCm39) |
|
probably benign |
Het |
| Pogz |
A |
G |
3: 94,783,947 (GRCm39) |
K545E |
possibly damaging |
Het |
| Ppp3cb |
T |
C |
14: 20,553,309 (GRCm39) |
|
probably null |
Het |
| Prl |
G |
A |
13: 27,248,911 (GRCm39) |
D189N |
probably damaging |
Het |
| Prpf6 |
A |
G |
2: 181,292,920 (GRCm39) |
N794S |
probably benign |
Het |
| Prr36 |
G |
A |
8: 4,263,930 (GRCm39) |
Q579* |
probably null |
Het |
| Ptprq |
A |
T |
10: 107,479,855 (GRCm39) |
Y1138* |
probably null |
Het |
| Rabepk |
A |
T |
2: 34,675,592 (GRCm39) |
H179Q |
probably damaging |
Het |
| Rest |
T |
C |
5: 77,430,598 (GRCm39) |
S1006P |
probably damaging |
Het |
| Rimklb |
A |
C |
6: 122,441,175 (GRCm39) |
|
probably benign |
Het |
| Rnpepl1 |
T |
C |
1: 92,846,587 (GRCm39) |
|
probably benign |
Het |
| Ro60 |
A |
T |
1: 143,633,489 (GRCm39) |
D536E |
possibly damaging |
Het |
| Sacs |
T |
A |
14: 61,428,928 (GRCm39) |
L329Q |
probably damaging |
Het |
| Safb |
C |
T |
17: 56,913,025 (GRCm39) |
R914C |
probably damaging |
Het |
| Setd5 |
A |
T |
6: 113,091,994 (GRCm39) |
I272F |
probably damaging |
Het |
| Sgk1 |
G |
T |
10: 21,872,209 (GRCm39) |
A262S |
probably benign |
Het |
| Skint2 |
G |
A |
4: 112,481,238 (GRCm39) |
V34I |
possibly damaging |
Het |
| Skint5 |
G |
C |
4: 113,512,869 (GRCm39) |
Q888E |
unknown |
Het |
| Slc4a3 |
T |
C |
1: 75,528,472 (GRCm39) |
|
probably benign |
Het |
| Sox10 |
T |
C |
15: 79,047,519 (GRCm39) |
E133G |
probably damaging |
Het |
| Spryd3 |
G |
A |
15: 102,038,835 (GRCm39) |
R129* |
probably null |
Het |
| Stag1 |
T |
A |
9: 100,810,144 (GRCm39) |
N782K |
probably benign |
Het |
| Stam |
T |
C |
2: 14,122,306 (GRCm39) |
L132P |
probably damaging |
Het |
| Stard9 |
T |
A |
2: 120,528,077 (GRCm39) |
S1445T |
probably damaging |
Het |
| Syt5 |
C |
T |
7: 4,546,108 (GRCm39) |
R94Q |
probably benign |
Het |
| Tbc1d23 |
A |
T |
16: 56,992,177 (GRCm39) |
H594Q |
probably damaging |
Het |
| Tecta |
T |
A |
9: 42,249,235 (GRCm39) |
I1871F |
probably damaging |
Het |
| Tek |
A |
G |
4: 94,692,549 (GRCm39) |
D219G |
probably benign |
Het |
| Thrb |
T |
C |
14: 18,033,643 (GRCm38) |
F469L |
probably damaging |
Het |
| Tyr |
T |
C |
7: 87,142,429 (GRCm39) |
S44G |
possibly damaging |
Het |
| Usp20 |
T |
A |
2: 30,907,487 (GRCm39) |
V673E |
probably benign |
Het |
| Usp28 |
T |
C |
9: 48,948,513 (GRCm39) |
S873P |
probably damaging |
Het |
| Usp43 |
C |
T |
11: 67,788,100 (GRCm39) |
V306M |
possibly damaging |
Het |
| Wdr17 |
G |
T |
8: 55,104,456 (GRCm39) |
|
probably null |
Het |
| Wsb2 |
T |
G |
5: 117,514,744 (GRCm39) |
|
probably benign |
Het |
| Xkrx |
A |
T |
X: 133,051,715 (GRCm39) |
L312Q |
probably damaging |
Het |
|
| Other mutations in Clca3a2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00419:Clca3a2
|
APN |
3 |
144,804,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01019:Clca3a2
|
APN |
3 |
144,519,388 (GRCm39) |
nonsense |
probably null |
|
|
IGL01337:Clca3a2
|
APN |
3 |
144,800,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Clca3a2
|
APN |
3 |
144,783,629 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01595:Clca3a2
|
APN |
3 |
144,793,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Clca3a2
|
APN |
3 |
144,522,916 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01704:Clca3a2
|
APN |
3 |
144,800,979 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01779:Clca3a2
|
APN |
3 |
144,525,139 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02066:Clca3a2
|
APN |
3 |
144,519,216 (GRCm39) |
missense |
probably benign |
|
|
IGL02301:Clca3a2
|
APN |
3 |
144,512,133 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02416:Clca3a2
|
APN |
3 |
144,790,777 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02455:Clca3a2
|
APN |
3 |
144,787,172 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02481:Clca3a2
|
APN |
3 |
144,790,701 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02526:Clca3a2
|
APN |
3 |
144,793,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02619:Clca3a2
|
APN |
3 |
144,512,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02797:Clca3a2
|
APN |
3 |
144,787,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02852:Clca3a2
|
APN |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02901:Clca3a2
|
APN |
3 |
144,522,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03162:Clca3a2
|
APN |
3 |
144,512,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03253:Clca3a2
|
APN |
3 |
144,777,324 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03256:Clca3a2
|
APN |
3 |
144,792,153 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL03294:Clca3a2
|
APN |
3 |
144,803,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3370:Clca3a2
|
UTSW |
3 |
144,783,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Clca3a2
|
UTSW |
3 |
144,522,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0244:Clca3a2
|
UTSW |
3 |
144,519,659 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0542:Clca3a2
|
UTSW |
3 |
144,781,571 (GRCm39) |
splice site |
probably benign |
|
|
R0629:Clca3a2
|
UTSW |
3 |
144,778,000 (GRCm39) |
missense |
probably benign |
|
|
R1249:Clca3a2
|
UTSW |
3 |
144,508,765 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1370:Clca3a2
|
UTSW |
3 |
144,519,624 (GRCm39) |
splice site |
probably benign |
|
|
R1488:Clca3a2
|
UTSW |
3 |
144,789,925 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1523:Clca3a2
|
UTSW |
3 |
144,777,405 (GRCm39) |
nonsense |
probably null |
|
|
R1568:Clca3a2
|
UTSW |
3 |
144,781,410 (GRCm39) |
nonsense |
probably null |
|
|
R1586:Clca3a2
|
UTSW |
3 |
144,516,477 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1650:Clca3a2
|
UTSW |
3 |
144,797,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Clca3a2
|
UTSW |
3 |
144,787,171 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1776:Clca3a2
|
UTSW |
3 |
144,519,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1869:Clca3a2
|
UTSW |
3 |
144,512,164 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1871:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1919:Clca3a2
|
UTSW |
3 |
144,516,457 (GRCm39) |
missense |
probably benign |
|
|
R1923:Clca3a2
|
UTSW |
3 |
144,511,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Clca3a2
|
UTSW |
3 |
144,783,699 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Clca3a2
|
UTSW |
3 |
144,519,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2242:Clca3a2
|
UTSW |
3 |
144,796,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2324:Clca3a2
|
UTSW |
3 |
144,512,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2937:Clca3a2
|
UTSW |
3 |
144,519,679 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3429:Clca3a2
|
UTSW |
3 |
144,512,088 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3434:Clca3a2
|
UTSW |
3 |
144,514,522 (GRCm39) |
unclassified |
probably benign |
|
|
R3551:Clca3a2
|
UTSW |
3 |
144,508,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3751:Clca3a2
|
UTSW |
3 |
144,777,216 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3952:Clca3a2
|
UTSW |
3 |
144,508,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4383:Clca3a2
|
UTSW |
3 |
144,512,081 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4496:Clca3a2
|
UTSW |
3 |
144,797,926 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4518:Clca3a2
|
UTSW |
3 |
144,514,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4598:Clca3a2
|
UTSW |
3 |
144,511,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4802:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4816:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4934:Clca3a2
|
UTSW |
3 |
144,523,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Clca3a2
|
UTSW |
3 |
144,512,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4962:Clca3a2
|
UTSW |
3 |
144,783,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Clca3a2
|
UTSW |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Clca3a2
|
UTSW |
3 |
144,511,599 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5275:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5344:Clca3a2
|
UTSW |
3 |
144,793,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Clca3a2
|
UTSW |
3 |
144,503,286 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Clca3a2
|
UTSW |
3 |
144,789,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5656:Clca3a2
|
UTSW |
3 |
144,503,393 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5931:Clca3a2
|
UTSW |
3 |
144,797,886 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6059:Clca3a2
|
UTSW |
3 |
144,516,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6155:Clca3a2
|
UTSW |
3 |
144,525,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6181:Clca3a2
|
UTSW |
3 |
144,796,469 (GRCm39) |
nonsense |
probably null |
|
|
R6254:Clca3a2
|
UTSW |
3 |
144,507,895 (GRCm39) |
missense |
probably benign |
|
|
R6336:Clca3a2
|
UTSW |
3 |
144,512,239 (GRCm39) |
missense |
probably benign |
|
|
R6470:Clca3a2
|
UTSW |
3 |
144,510,024 (GRCm39) |
splice site |
probably null |
|
|
R6593:Clca3a2
|
UTSW |
3 |
144,514,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6598:Clca3a2
|
UTSW |
3 |
144,792,246 (GRCm39) |
nonsense |
probably null |
|
|
R6631:Clca3a2
|
UTSW |
3 |
144,519,405 (GRCm39) |
missense |
probably benign |
|
|
R6826:Clca3a2
|
UTSW |
3 |
144,523,815 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6836:Clca3a2
|
UTSW |
3 |
144,512,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6896:Clca3a2
|
UTSW |
3 |
144,514,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Clca3a2
|
UTSW |
3 |
144,803,545 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7211:Clca3a2
|
UTSW |
3 |
144,519,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7229:Clca3a2
|
UTSW |
3 |
144,789,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7256:Clca3a2
|
UTSW |
3 |
144,796,608 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7324:Clca3a2
|
UTSW |
3 |
144,514,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Clca3a2
|
UTSW |
3 |
144,804,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7411:Clca3a2
|
UTSW |
3 |
144,507,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7486:Clca3a2
|
UTSW |
3 |
144,503,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7491:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7521:Clca3a2
|
UTSW |
3 |
144,507,674 (GRCm39) |
makesense |
probably null |
|
|
R7813:Clca3a2
|
UTSW |
3 |
144,790,726 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7889:Clca3a2
|
UTSW |
3 |
144,516,574 (GRCm39) |
nonsense |
probably null |
|
|
R7946:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7991:Clca3a2
|
UTSW |
3 |
144,519,756 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8022:Clca3a2
|
UTSW |
3 |
144,511,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8077:Clca3a2
|
UTSW |
3 |
144,777,288 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8169:Clca3a2
|
UTSW |
3 |
144,783,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Clca3a2
|
UTSW |
3 |
144,793,719 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8300:Clca3a2
|
UTSW |
3 |
144,804,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8344:Clca3a2
|
UTSW |
3 |
144,511,703 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8350:Clca3a2
|
UTSW |
3 |
144,783,668 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8367:Clca3a2
|
UTSW |
3 |
144,523,508 (GRCm39) |
splice site |
probably null |
|
|
R8371:Clca3a2
|
UTSW |
3 |
144,513,114 (GRCm39) |
nonsense |
probably null |
|
|
R8814:Clca3a2
|
UTSW |
3 |
144,503,525 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8854:Clca3a2
|
UTSW |
3 |
144,783,852 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8876:Clca3a2
|
UTSW |
3 |
144,777,360 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8887:Clca3a2
|
UTSW |
3 |
144,790,810 (GRCm39) |
nonsense |
probably null |
|
|
R9006:Clca3a2
|
UTSW |
3 |
144,783,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9031:Clca3a2
|
UTSW |
3 |
144,511,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Clca3a2
|
UTSW |
3 |
144,519,447 (GRCm39) |
splice site |
probably benign |
|
|
R9093:Clca3a2
|
UTSW |
3 |
144,781,481 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9190:Clca3a2
|
UTSW |
3 |
144,796,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9201:Clca3a2
|
UTSW |
3 |
144,519,684 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9209:Clca3a2
|
UTSW |
3 |
144,778,005 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9261:Clca3a2
|
UTSW |
3 |
144,525,158 (GRCm39) |
missense |
probably benign |
|
|
R9469:Clca3a2
|
UTSW |
3 |
144,507,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9501:Clca3a2
|
UTSW |
3 |
144,777,322 (GRCm39) |
nonsense |
probably null |
|
|
R9515:Clca3a2
|
UTSW |
3 |
144,508,808 (GRCm39) |
nonsense |
probably null |
|
|
R9569:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9664:Clca3a2
|
UTSW |
3 |
144,503,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Clca3a2
|
UTSW |
3 |
144,792,265 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Clca3a2
|
UTSW |
3 |
144,792,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGAAGGAGTTTGTCGTCCCAAGG -3'
(R):5'- AAGTCCACTGGAATGCTGATTCAGG -3'
Sequencing Primer
(F):5'- GTCGTCCCAAGGATGTACTTACAG -3'
(R):5'- TGGCAATACAAATGCTTGTCC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation