Mutagenetix > Incidental Mutation

Incidental Mutation 'R5595:Htt'

437764

Institutional Source

Beutler Lab

Gene Symbol

Htt

Ensembl Gene

ENSMUSG00000029104

Gene Name

huntingtin

Synonyms

HD, Hdh, htt, huntingtin, IT15

MMRRC Submission

043147-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5595 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

34761740-34912534 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 34905397 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Glutamic Acid at position 2825 (V2825E)

Ref Sequence

ENSEMBL: ENSMUSP00000078945 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080036]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000080036
AA Change: V2825E

PolyPhen 2 Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000078945
Gene: ENSMUSG00000029104
AA Change: V2825E

Domain	Start	End	E-Value	Type
low complexity region	18	65	N/A	INTRINSIC
SCOP:d1qgra_	92	370	1e-12	SMART
low complexity region	371	388	N/A	INTRINSIC
low complexity region	432	453	N/A	INTRINSIC
low complexity region	1150	1161	N/A	INTRINSIC
low complexity region	1423	1441	N/A	INTRINSIC
Pfam:DUF3652	1494	1534	9.3e-20	PFAM
low complexity region	1812	1822	N/A	INTRINSIC
Blast:GAF	1866	2040	1e-104	BLAST
low complexity region	2461	2472	N/A	INTRINSIC
low complexity region	2611	2621	N/A	INTRINSIC
low complexity region	2622	2635	N/A	INTRINSIC
low complexity region	2857	2872	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124272

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201636

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.7%
20x: 96.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed. The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. This gene contains an upstream open reading frame in the 5' UTR that inhibits expression of the huntingtin gene product through translational repression. [provided by RefSeq, Jul 2016]
PHENOTYPE: Null mutants gastrulate abnormally and die in utero. Conditional mutants are small with progressive neurodegeneration. Knock-ins of 20-150 CAG repeat units variably mimic Huntington's with late-onset motor defects, reactive gliosis and neuronal inclusions. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930562C15Rik	T	C	16: 4,864,279 (GRCm38)	F991S	probably benign	Het
4931406B18Rik	A	G	7: 43,497,872 (GRCm38)	I218T	possibly damaging	Het
4931440F15Rik	T	C	11: 29,824,288 (GRCm38)	N390D	probably benign	Het
9930111J21Rik2	C	T	11: 49,019,711 (GRCm38)	A632T	possibly damaging	Het
Akt1	A	T	12: 112,658,616 (GRCm38)	L166Q	probably null	Het
Alpk2	A	T	18: 65,266,248 (GRCm38)	D2086E	probably damaging	Het
Ankrd11	A	T	8: 122,894,304 (GRCm38)	C915*	probably null	Het
Ankrd44	T	C	1: 54,762,347 (GRCm38)	T274A	probably damaging	Het
Ankrd44	A	T	1: 54,735,050 (GRCm38)	I398K	probably damaging	Het
Arhgef2	A	G	3: 88,642,976 (GRCm38)	T663A	probably benign	Het
BC048403	T	C	10: 121,740,147 (GRCm38)		probably benign	Het
Btbd16	C	A	7: 130,823,304 (GRCm38)	Q472K	probably damaging	Het
Btbd16	G	A	7: 130,823,303 (GRCm38)	M471I	possibly damaging	Het
Cdc37	G	A	9: 21,143,213 (GRCm38)	R39C	probably damaging	Het
Cnnm1	A	G	19: 43,465,157 (GRCm38)	N537S	possibly damaging	Het
Cop1	T	A	1: 159,250,073 (GRCm38)	D159E	probably benign	Het
Crtac1	C	T	19: 42,413,951 (GRCm38)	V73I	probably benign	Het
Cryz	T	A	3: 154,606,518 (GRCm38)	V84E	probably damaging	Het
Ctnnd2	C	T	15: 30,669,543 (GRCm38)	L433F	probably benign	Het
Ctsq	C	A	13: 61,037,060 (GRCm38)	D271Y	probably benign	Het
Cyp3a25	A	C	5: 145,994,863 (GRCm38)		probably null	Het
Dmbt1	G	C	7: 131,054,067 (GRCm38)	W412C	probably benign	Het
Eif4e1b	G	A	13: 54,786,716 (GRCm38)	V131I	possibly damaging	Het
Epha1	A	G	6: 42,364,634 (GRCm38)	V494A	possibly damaging	Het
Fbxl4	T	C	4: 22,433,641 (GRCm38)	S593P	probably damaging	Het
Fbxo41	G	A	6: 85,479,901 (GRCm38)	P429S	probably benign	Het
Fgfr3	G	A	5: 33,730,003 (GRCm38)	C204Y	probably damaging	Het
Gbf1	T	C	19: 46,284,422 (GRCm38)	V1665A	possibly damaging	Het
Irs1	A	T	1: 82,289,925 (GRCm38)	V190E	probably damaging	Het
Klk1	T	C	7: 44,228,737 (GRCm38)		probably null	Het
Kmt2d	T	C	15: 98,850,024 (GRCm38)		probably benign	Het
Meox1	T	C	11: 101,879,343 (GRCm38)	E186G	probably damaging	Het
Micu2	G	A	14: 57,971,744 (GRCm38)	R86W	probably damaging	Het
Mrgprb1	A	T	7: 48,447,684 (GRCm38)	I160K	probably damaging	Het
Nckap1l	T	A	15: 103,475,658 (GRCm38)	M561K	possibly damaging	Het
Olfr1199	A	T	2: 88,756,405 (GRCm38)	I90N	probably damaging	Het
Olfr605	A	T	7: 103,442,428 (GRCm38)	S232T	probably damaging	Het
Olfr689	A	T	7: 105,314,006 (GRCm38)	M1L	probably benign	Het
Otoa	T	A	7: 121,121,977 (GRCm38)	L405H	probably damaging	Het
Phyhip	A	T	14: 70,466,874 (GRCm38)	M178L	probably benign	Het
Pkd1l3	A	T	8: 109,655,520 (GRCm38)	N1630I	probably damaging	Het
Plek2	T	A	12: 78,894,109 (GRCm38)	T247S	probably benign	Het
Rhbdl3	T	C	11: 80,337,583 (GRCm38)	V293A	probably damaging	Het
Rock2	T	A	12: 16,942,809 (GRCm38)	F193Y	probably damaging	Het
Scn3a	C	T	2: 65,460,713 (GRCm38)	M1896I	probably benign	Het
Snrnp200	T	C	2: 127,226,013 (GRCm38)	V810A	probably damaging	Het
Taar4	G	A	10: 23,960,741 (GRCm38)	S83N	probably damaging	Het
Tdpoz4	A	T	3: 93,797,499 (GRCm38)	T368S	probably benign	Het
Tec	T	A	5: 72,768,744 (GRCm38)	I322F	possibly damaging	Het
Teddm2	T	C	1: 153,850,400 (GRCm38)	I190V	probably benign	Het
Tmem117	A	G	15: 95,094,884 (GRCm38)	E475G	probably damaging	Het
Trip10	T	A	17: 57,262,460 (GRCm38)	Y495N	probably damaging	Het
Ush2a	T	C	1: 188,906,498 (GRCm38)	V4035A	possibly damaging	Het
Utrn	C	T	10: 12,682,318 (GRCm38)	V1466M	possibly damaging	Het
Vasp	A	G	7: 19,257,891 (GRCm38)		probably benign	Het
Vmn1r89	A	T	7: 13,219,930 (GRCm38)	M130L	possibly damaging	Het
Vmn2r2	A	T	3: 64,126,615 (GRCm38)	D495E	possibly damaging	Het
Zfp213	A	G	17: 23,561,186 (GRCm38)	V120A	possibly damaging	Het

Other mutations in Htt

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00230:Htt	APN	5	34,799,408 (GRCm38)	missense	probably benign	0.00
IGL00233:Htt	APN	5	34,896,026 (GRCm38)	splice site	probably null
IGL00559:Htt	APN	5	34,849,104 (GRCm38)	splice site	probably benign
IGL00765:Htt	APN	5	34,877,425 (GRCm38)	splice site	probably benign
IGL00950:Htt	APN	5	34,891,441 (GRCm38)	missense	probably benign
IGL00953:Htt	APN	5	34,818,677 (GRCm38)	missense	probably benign	0.04
IGL00957:Htt	APN	5	34,806,724 (GRCm38)	missense	probably benign
IGL01314:Htt	APN	5	34,878,856 (GRCm38)	missense	probably benign
IGL01412:Htt	APN	5	34,898,572 (GRCm38)	missense	probably damaging	0.98
IGL01510:Htt	APN	5	34,907,512 (GRCm38)	missense	probably damaging	1.00
IGL01617:Htt	APN	5	34,876,755 (GRCm38)	missense	possibly damaging	0.67
IGL01893:Htt	APN	5	34,876,830 (GRCm38)	missense	probably damaging	1.00
IGL01914:Htt	APN	5	34,829,709 (GRCm38)	missense	probably benign
IGL01994:Htt	APN	5	34,832,604 (GRCm38)	missense	possibly damaging	0.83
IGL02102:Htt	APN	5	34,891,481 (GRCm38)	splice site	probably benign
IGL02381:Htt	APN	5	34,829,760 (GRCm38)	missense	probably benign	0.03
IGL02529:Htt	APN	5	34,819,043 (GRCm38)	splice site	probably benign
IGL02678:Htt	APN	5	34,899,902 (GRCm38)	missense	probably damaging	1.00
IGL02707:Htt	APN	5	34,829,881 (GRCm38)	critical splice donor site	probably null
IGL02731:Htt	APN	5	34,803,793 (GRCm38)	missense	probably benign	0.41
IGL02931:Htt	APN	5	34,876,753 (GRCm38)	missense	probably damaging	1.00
IGL03167:Htt	APN	5	34,818,986 (GRCm38)	missense	probably damaging	0.98
IGL03343:Htt	APN	5	34,826,041 (GRCm38)	missense	probably benign
IGL03344:Htt	APN	5	34,879,828 (GRCm38)	missense	probably benign	0.39
IGL03344:Htt	APN	5	34,907,466 (GRCm38)	missense	probably benign	0.02
IGL03366:Htt	APN	5	34,907,580 (GRCm38)	missense	probably damaging	1.00
IGL03410:Htt	APN	5	34,799,445 (GRCm38)	missense	probably damaging	0.99
Chalk	UTSW	5	34,907,086 (GRCm38)	missense	possibly damaging	0.86
IGL02796:Htt	UTSW	5	34,877,482 (GRCm38)	missense	probably benign	0.43
PIT4377001:Htt	UTSW	5	34,875,965 (GRCm38)	missense	probably benign	0.10
R0013:Htt	UTSW	5	34,820,104 (GRCm38)	missense	probably benign	0.25
R0049:Htt	UTSW	5	34,908,662 (GRCm38)	missense	probably damaging	0.97
R0049:Htt	UTSW	5	34,908,662 (GRCm38)	missense	probably damaging	0.97
R0056:Htt	UTSW	5	34,826,078 (GRCm38)	splice site	probably benign
R0207:Htt	UTSW	5	34,896,908 (GRCm38)	missense	probably benign	0.11
R0329:Htt	UTSW	5	34,817,134 (GRCm38)	splice site	probably benign
R0494:Htt	UTSW	5	34,821,844 (GRCm38)	missense	possibly damaging	0.73
R0548:Htt	UTSW	5	34,870,746 (GRCm38)	missense	probably damaging	1.00
R0601:Htt	UTSW	5	34,846,003 (GRCm38)	missense	probably benign	0.08
R0799:Htt	UTSW	5	34,817,753 (GRCm38)	missense	probably benign	0.00
R0947:Htt	UTSW	5	34,898,924 (GRCm38)	missense	probably damaging	1.00
R1053:Htt	UTSW	5	34,851,217 (GRCm38)	critical splice acceptor site	probably null
R1147:Htt	UTSW	5	34,851,252 (GRCm38)	missense	probably damaging	0.98
R1147:Htt	UTSW	5	34,851,252 (GRCm38)	missense	probably damaging	0.98
R1478:Htt	UTSW	5	34,803,827 (GRCm38)	missense	probably damaging	0.99
R1573:Htt	UTSW	5	34,864,374 (GRCm38)	splice site	probably benign
R1677:Htt	UTSW	5	34,828,574 (GRCm38)	missense	probably damaging	1.00
R1792:Htt	UTSW	5	34,907,199 (GRCm38)	missense	probably damaging	1.00
R1816:Htt	UTSW	5	34,803,740 (GRCm38)	missense	probably benign	0.01
R1833:Htt	UTSW	5	34,905,748 (GRCm38)	splice site	probably benign
R1837:Htt	UTSW	5	34,819,023 (GRCm38)	missense	probably benign	0.00
R1846:Htt	UTSW	5	34,848,944 (GRCm38)	missense	probably damaging	0.98
R1875:Htt	UTSW	5	34,794,112 (GRCm38)	missense	probably benign	0.05
R1899:Htt	UTSW	5	34,907,085 (GRCm38)	missense	probably benign	0.01
R2013:Htt	UTSW	5	34,852,871 (GRCm38)	missense	probably damaging	0.99
R2062:Htt	UTSW	5	34,825,982 (GRCm38)	missense	probably benign	0.00
R2064:Htt	UTSW	5	34,825,982 (GRCm38)	missense	probably benign	0.00
R2067:Htt	UTSW	5	34,825,982 (GRCm38)	missense	probably benign	0.00
R2068:Htt	UTSW	5	34,825,982 (GRCm38)	missense	probably benign	0.00
R2131:Htt	UTSW	5	34,877,109 (GRCm38)	missense	possibly damaging	0.50
R2162:Htt	UTSW	5	34,821,718 (GRCm38)	missense	probably benign	0.44
R2169:Htt	UTSW	5	34,877,475 (GRCm38)	missense	probably benign	0.08
R2345:Htt	UTSW	5	34,826,004 (GRCm38)	missense	possibly damaging	0.80
R2433:Htt	UTSW	5	34,907,541 (GRCm38)	missense	possibly damaging	0.65
R3027:Htt	UTSW	5	34,820,095 (GRCm38)	missense	possibly damaging	0.85
R3123:Htt	UTSW	5	34,804,531 (GRCm38)	missense	probably benign
R3125:Htt	UTSW	5	34,804,531 (GRCm38)	missense	probably benign
R3717:Htt	UTSW	5	34,811,522 (GRCm38)	splice site	probably benign
R3758:Htt	UTSW	5	34,895,970 (GRCm38)	missense	probably damaging	0.97
R3805:Htt	UTSW	5	34,877,204 (GRCm38)	splice site	probably null
R3833:Htt	UTSW	5	34,821,718 (GRCm38)	missense	probably benign	0.44
R4066:Htt	UTSW	5	34,878,847 (GRCm38)	missense	probably benign
R4272:Htt	UTSW	5	34,849,069 (GRCm38)	missense	possibly damaging	0.96
R4625:Htt	UTSW	5	34,829,785 (GRCm38)	missense	probably damaging	0.99
R4634:Htt	UTSW	5	34,875,948 (GRCm38)	missense	probably benign	0.06
R4655:Htt	UTSW	5	34,906,132 (GRCm38)	missense	probably benign	0.06
R4679:Htt	UTSW	5	34,820,080 (GRCm38)	missense	probably benign
R4684:Htt	UTSW	5	34,852,765 (GRCm38)	missense	probably damaging	1.00
R4832:Htt	UTSW	5	34,824,840 (GRCm38)	missense	probably benign	0.01
R4833:Htt	UTSW	5	34,852,225 (GRCm38)	missense	probably damaging	0.98
R4973:Htt	UTSW	5	34,813,023 (GRCm38)	missense	probably damaging	0.99
R5095:Htt	UTSW	5	34,824,395 (GRCm38)	missense	possibly damaging	0.89
R5132:Htt	UTSW	5	34,905,679 (GRCm38)	missense	possibly damaging	0.89
R5351:Htt	UTSW	5	34,803,833 (GRCm38)	missense	probably damaging	0.99
R5361:Htt	UTSW	5	34,907,584 (GRCm38)	missense	possibly damaging	0.47
R5399:Htt	UTSW	5	34,877,151 (GRCm38)	missense	probably damaging	0.98
R5462:Htt	UTSW	5	34,885,507 (GRCm38)	nonsense	probably null
R5552:Htt	UTSW	5	34,821,774 (GRCm38)	missense	probably benign
R5566:Htt	UTSW	5	34,849,075 (GRCm38)	missense	probably damaging	1.00
R5617:Htt	UTSW	5	34,870,806 (GRCm38)	missense	possibly damaging	0.77
R5835:Htt	UTSW	5	34,813,190 (GRCm38)	missense	probably benign	0.16
R5891:Htt	UTSW	5	34,870,823 (GRCm38)	missense	possibly damaging	0.62
R6158:Htt	UTSW	5	34,907,086 (GRCm38)	missense	possibly damaging	0.86
R6159:Htt	UTSW	5	34,804,676 (GRCm38)	missense	probably benign	0.08
R6169:Htt	UTSW	5	34,907,473 (GRCm38)	missense	probably damaging	1.00
R6242:Htt	UTSW	5	34,846,012 (GRCm38)	missense	probably damaging	1.00
R6274:Htt	UTSW	5	34,852,087 (GRCm38)	missense	possibly damaging	0.81
R6280:Htt	UTSW	5	34,870,759 (GRCm38)	missense	probably benign	0.00
R6294:Htt	UTSW	5	34,821,826 (GRCm38)	missense	probably benign
R6331:Htt	UTSW	5	34,895,887 (GRCm38)	missense	possibly damaging	0.89
R6448:Htt	UTSW	5	34,875,992 (GRCm38)	missense	probably benign	0.05
R6474:Htt	UTSW	5	34,824,895 (GRCm38)	missense	probably benign	0.06
R6592:Htt	UTSW	5	34,877,044 (GRCm38)	missense	possibly damaging	0.92
R6818:Htt	UTSW	5	34,782,767 (GRCm38)	missense	probably damaging	0.99
R6830:Htt	UTSW	5	34,834,326 (GRCm38)	missense	possibly damaging	0.82
R6920:Htt	UTSW	5	34,877,100 (GRCm38)	missense	probably null	1.00
R6962:Htt	UTSW	5	34,899,771 (GRCm38)	critical splice acceptor site	probably null
R7057:Htt	UTSW	5	34,821,723 (GRCm38)	missense	probably null	0.05
R7144:Htt	UTSW	5	34,846,006 (GRCm38)	missense	probably damaging	1.00
R7166:Htt	UTSW	5	34,852,894 (GRCm38)	missense	probably benign	0.42
R7329:Htt	UTSW	5	34,829,755 (GRCm38)	missense	probably benign	0.03
R7378:Htt	UTSW	5	34,803,799 (GRCm38)	missense	probably benign	0.04
R7418:Htt	UTSW	5	34,790,353 (GRCm38)	missense	possibly damaging	0.55
R7495:Htt	UTSW	5	34,811,477 (GRCm38)	missense	probably benign	0.00
R7554:Htt	UTSW	5	34,864,740 (GRCm38)	missense	probably damaging	0.97
R7575:Htt	UTSW	5	34,905,643 (GRCm38)	missense	probably damaging	1.00
R7763:Htt	UTSW	5	34,852,190 (GRCm38)	missense	probably damaging	1.00
R7782:Htt	UTSW	5	34,882,992 (GRCm38)	missense	probably benign	0.03
R7850:Htt	UTSW	5	34,852,287 (GRCm38)	splice site	probably null
R7870:Htt	UTSW	5	34,898,547 (GRCm38)	missense	possibly damaging	0.77
R7871:Htt	UTSW	5	34,864,649 (GRCm38)	missense	probably benign	0.00
R7879:Htt	UTSW	5	34,823,908 (GRCm38)	missense	probably benign
R7992:Htt	UTSW	5	34,829,881 (GRCm38)	critical splice donor site	probably null
R8058:Htt	UTSW	5	34,820,100 (GRCm38)	missense	probably benign
R8168:Htt	UTSW	5	34,882,956 (GRCm38)	missense	probably benign	0.00
R8188:Htt	UTSW	5	34,761,943 (GRCm38)	missense	probably benign	0.03
R8262:Htt	UTSW	5	34,895,960 (GRCm38)	missense	probably benign
R8343:Htt	UTSW	5	34,905,724 (GRCm38)	missense	probably damaging	1.00
R8353:Htt	UTSW	5	34,877,155 (GRCm38)	missense	possibly damaging	0.49
R8769:Htt	UTSW	5	34,820,289 (GRCm38)	missense	probably benign	0.05
R8808:Htt	UTSW	5	34,889,447 (GRCm38)	missense	probably benign	0.10
R8825:Htt	UTSW	5	34,825,960 (GRCm38)	missense	probably benign	0.24
R8843:Htt	UTSW	5	34,889,465 (GRCm38)	missense	possibly damaging	0.92
R8856:Htt	UTSW	5	34,903,331 (GRCm38)	missense	probably benign	0.44
R8882:Htt	UTSW	5	34,821,717 (GRCm38)	missense	probably benign
R8898:Htt	UTSW	5	34,819,032 (GRCm38)	missense	probably benign	0.01
R8964:Htt	UTSW	5	34,905,376 (GRCm38)	missense	probably benign	0.09
R8987:Htt	UTSW	5	34,820,024 (GRCm38)	missense	probably benign	0.18
R8991:Htt	UTSW	5	34,905,718 (GRCm38)	missense	probably damaging	1.00
R9005:Htt	UTSW	5	34,817,751 (GRCm38)	missense	possibly damaging	0.92
R9019:Htt	UTSW	5	34,866,576 (GRCm38)	missense	probably damaging	1.00
R9057:Htt	UTSW	5	34,852,110 (GRCm38)	missense	possibly damaging	0.86
R9157:Htt	UTSW	5	34,829,827 (GRCm38)	missense	probably null	0.89
R9205:Htt	UTSW	5	34,819,023 (GRCm38)	missense	probably benign	0.00
R9223:Htt	UTSW	5	34,905,348 (GRCm38)	missense	probably benign	0.01
R9243:Htt	UTSW	5	34,898,932 (GRCm38)	splice site	probably benign
R9329:Htt	UTSW	5	34,832,613 (GRCm38)	missense	possibly damaging	0.69
R9355:Htt	UTSW	5	34,895,903 (GRCm38)	missense	probably benign
R9402:Htt	UTSW	5	34,848,980 (GRCm38)	missense	probably damaging	1.00
R9446:Htt	UTSW	5	34,761,928 (GRCm38)	missense	probably benign
R9716:Htt	UTSW	5	34,854,675 (GRCm38)	missense	probably damaging	1.00
Z1177:Htt	UTSW	5	34,852,231 (GRCm38)	missense	probably null	0.87

Predicted Primers

PCR Primer
(F):5'- CTAGGCCATCCAGGTGAAAAG -3'
(R):5'- TGGACTCCTCACTTCCAGAC -3'

Sequencing Primer
(F):5'- CAGAGCTCTGTACTCAATAGATGTGG -3'
(R):5'- TCACTTCCAGACAGCATTACTC -3'

Posted On

2016-10-26