Incidental Mutation 'R5579:Dock9'
| ID |
438321 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dock9
|
| Ensembl Gene |
ENSMUSG00000025558 |
| Gene Name |
dedicator of cytokinesis 9 |
| Synonyms |
D14Wsu89e, Zizimin1, B230309H04Rik |
| MMRRC Submission |
043267-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5579 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
121542046-121797837 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 121599695 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 67
(L67Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148303
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040700]
[ENSMUST00000100299]
[ENSMUST00000212181]
[ENSMUST00000212376]
[ENSMUST00000212416]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040700
AA Change: L1271Q
PolyPhen 2
Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000047881
Gene: ENSMUSG00000025558
AA Change: L1271Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
151 |
5.6e-36 |
PFAM |
|
PH
|
172 |
280 |
1.38e-16 |
SMART |
|
Blast:PH
|
297 |
372 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
631 |
822 |
5.3e-51 |
PFAM |
|
Pfam:DHR-2
|
1523 |
2068 |
2.1e-212 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000100299
AA Change: L1273Q
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000097872
Gene: ENSMUSG00000025558
AA Change: L1273Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
153 |
1.5e-32 |
PFAM |
|
PH
|
174 |
282 |
1.38e-16 |
SMART |
|
Blast:PH
|
299 |
374 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
632 |
825 |
1.3e-59 |
PFAM |
|
low complexity region
|
1752 |
1763 |
N/A |
INTRINSIC |
|
Pfam:Ded_cyto
|
1836 |
2013 |
2.4e-69 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211993
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212181
AA Change: L1271Q
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| Predicted Effect |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000212376
AA Change: L1285Q
PolyPhen 2
Score 0.645 (Sensitivity: 0.87; Specificity: 0.91)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212416
AA Change: L67Q
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 98.9%
- 20x: 97.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 114 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810403A07Rik |
T |
C |
3: 88,700,275 |
S345P |
probably benign |
Het |
| 6430573F11Rik |
T |
C |
8: 36,512,041 |
V266A |
probably benign |
Het |
| Abca3 |
G |
T |
17: 24,376,729 |
C352F |
probably damaging |
Het |
| Abce1 |
A |
T |
8: 79,700,586 |
I237N |
possibly damaging |
Het |
| Acrbp |
A |
G |
6: 125,061,099 |
D421G |
probably benign |
Het |
| Adam8 |
T |
A |
7: 139,988,984 |
Y201F |
probably benign |
Het |
| Adgrf1 |
T |
A |
17: 43,311,064 |
C731S |
probably damaging |
Het |
| AF067063 |
T |
A |
13: 119,828,415 |
M82L |
probably benign |
Het |
| Akap8l |
A |
T |
17: 32,321,942 |
I529N |
probably damaging |
Het |
| Akap9 |
G |
A |
5: 4,064,714 |
G114D |
possibly damaging |
Het |
| Alox12b |
T |
A |
11: 69,162,932 |
D158E |
probably benign |
Het |
| Ankrd11 |
A |
G |
8: 122,884,231 |
S2639P |
probably damaging |
Het |
| Ankrd42 |
T |
C |
7: 92,590,182 |
Y466C |
possibly damaging |
Het |
| Apobr |
T |
C |
7: 126,587,675 |
I786T |
probably benign |
Het |
| Arhgef12 |
C |
T |
9: 43,010,193 |
G329R |
probably benign |
Het |
| Btnl1 |
T |
C |
17: 34,381,552 |
|
probably null |
Het |
| Ccdc174 |
A |
G |
6: 91,881,350 |
|
probably null |
Het |
| Ccdc183 |
T |
C |
2: 25,615,422 |
D177G |
possibly damaging |
Het |
| Cd14 |
A |
G |
18: 36,726,235 |
Y56H |
probably benign |
Het |
| Cep162 |
G |
A |
9: 87,203,671 |
A1200V |
probably benign |
Het |
| Clic3 |
T |
C |
2: 25,458,307 |
L128P |
probably damaging |
Het |
| Cntnap5b |
A |
T |
1: 100,383,395 |
R538* |
probably null |
Het |
| Cntnap5b |
A |
T |
1: 100,383,399 |
Q539L |
probably benign |
Het |
| Coq7 |
A |
T |
7: 118,517,335 |
N214K |
unknown |
Het |
| Cramp1l |
G |
A |
17: 24,973,113 |
H1018Y |
possibly damaging |
Het |
| Crtac1 |
T |
A |
19: 42,304,806 |
D288V |
probably damaging |
Het |
| Dab2ip |
C |
T |
2: 35,715,327 |
R132* |
probably null |
Het |
| Dis3l |
C |
A |
9: 64,330,835 |
C125F |
probably benign |
Het |
| Dnmt1 |
A |
T |
9: 20,920,205 |
V543D |
probably damaging |
Het |
| Ehbp1 |
A |
T |
11: 22,137,846 |
S413T |
probably damaging |
Het |
| Endov |
A |
G |
11: 119,505,097 |
I158V |
probably benign |
Het |
| Epb41l4b |
A |
G |
4: 57,064,802 |
V469A |
possibly damaging |
Het |
| Etf1 |
G |
A |
18: 34,913,601 |
P119S |
probably damaging |
Het |
| Fam135a |
A |
G |
1: 24,029,727 |
L491P |
possibly damaging |
Het |
| Fancd2 |
A |
T |
6: 113,560,051 |
|
probably null |
Het |
| Fank1 |
T |
A |
7: 133,869,329 |
|
probably null |
Het |
| Fbxo18 |
A |
G |
2: 11,748,993 |
I846T |
probably damaging |
Het |
| Gas2l3 |
T |
C |
10: 89,414,066 |
T397A |
probably benign |
Het |
| Gga1 |
T |
C |
15: 78,893,188 |
V513A |
probably damaging |
Het |
| Ggt1 |
T |
C |
10: 75,585,948 |
V543A |
probably damaging |
Het |
| Gm11596 |
A |
T |
11: 99,792,891 |
C134* |
probably null |
Het |
| Gnal |
C |
T |
18: 67,088,771 |
R82C |
unknown |
Het |
| Hat1 |
T |
C |
2: 71,410,238 |
V92A |
possibly damaging |
Het |
| Icosl |
C |
T |
10: 78,073,763 |
R181C |
probably damaging |
Het |
| Ift46 |
A |
G |
9: 44,786,863 |
M208V |
possibly damaging |
Het |
| Ighv1-26 |
T |
C |
12: 114,788,599 |
K42E |
possibly damaging |
Het |
| Ipo5 |
A |
G |
14: 120,938,613 |
K617E |
probably benign |
Het |
| Irx5 |
A |
G |
8: 92,359,913 |
D208G |
probably benign |
Het |
| Itgal |
T |
G |
7: 127,306,929 |
V397G |
probably benign |
Het |
| Itpr2 |
G |
A |
6: 146,173,366 |
R2297* |
probably null |
Het |
| Itpr3 |
A |
G |
17: 27,113,519 |
D1779G |
probably damaging |
Het |
| Krt4 |
T |
A |
15: 101,921,234 |
E286D |
probably benign |
Het |
| Loxl4 |
C |
T |
19: 42,604,290 |
G317E |
probably damaging |
Het |
| Mapk6 |
T |
G |
9: 75,388,062 |
H718P |
possibly damaging |
Het |
| Mark2 |
A |
C |
19: 7,282,816 |
V14G |
probably damaging |
Het |
| Mbd5 |
A |
G |
2: 49,272,814 |
T1103A |
possibly damaging |
Het |
| Mcph1 |
A |
G |
8: 18,632,293 |
E482G |
probably benign |
Het |
| Mme |
G |
A |
3: 63,348,645 |
E509K |
probably damaging |
Het |
| Mrgbp |
A |
G |
2: 180,585,483 |
T204A |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,291,333 |
F430I |
probably damaging |
Het |
| Myo6 |
A |
G |
9: 80,217,720 |
D27G |
probably damaging |
Het |
| Ncoa6 |
A |
G |
2: 155,406,677 |
L1569S |
probably damaging |
Het |
| Ndc1 |
T |
A |
4: 107,380,704 |
F235Y |
possibly damaging |
Het |
| Nmur2 |
A |
T |
11: 56,033,009 |
S240T |
probably benign |
Het |
| Olfr1176 |
A |
T |
2: 88,340,413 |
I283F |
possibly damaging |
Het |
| Olfr301 |
T |
A |
7: 86,412,726 |
Y121* |
probably null |
Het |
| Olfr608 |
G |
A |
7: 103,470,914 |
V292M |
probably damaging |
Het |
| Osbpl1a |
A |
C |
18: 12,892,262 |
S333A |
probably benign |
Het |
| Osbpl1a |
G |
T |
18: 12,841,192 |
A62E |
probably damaging |
Het |
| Otud4 |
C |
T |
8: 79,664,108 |
T417I |
probably benign |
Het |
| Pagr1a |
T |
C |
7: 127,015,442 |
E197G |
probably damaging |
Het |
| Pcdh18 |
T |
C |
3: 49,744,977 |
Q1012R |
probably damaging |
Het |
| Pcdhgb5 |
A |
C |
18: 37,731,637 |
I162L |
probably benign |
Het |
| Pdpr |
T |
A |
8: 111,123,816 |
Y462N |
probably damaging |
Het |
| Pkhd1 |
A |
T |
1: 20,523,142 |
H1582Q |
probably damaging |
Het |
| Polr1b |
A |
G |
2: 129,110,108 |
K352R |
probably damaging |
Het |
| Poteg |
G |
A |
8: 27,448,037 |
V12M |
probably damaging |
Het |
| Pou2f1 |
A |
C |
1: 165,915,162 |
V54G |
probably damaging |
Het |
| Ppme1 |
A |
G |
7: 100,344,975 |
L177P |
probably damaging |
Het |
| Prkce |
A |
G |
17: 86,619,948 |
D550G |
probably damaging |
Het |
| Prrc2c |
A |
G |
1: 162,680,758 |
|
probably null |
Het |
| Ptpn22 |
A |
G |
3: 103,882,139 |
|
probably null |
Het |
| Rabif |
G |
A |
1: 134,506,205 |
V86M |
probably damaging |
Het |
| Rbm25 |
T |
A |
12: 83,668,507 |
M484K |
probably benign |
Het |
| Rcn2 |
G |
A |
9: 56,057,429 |
A224T |
probably benign |
Het |
| Rexo5 |
T |
A |
7: 119,834,403 |
|
probably null |
Het |
| Rnase1 |
A |
T |
14: 51,145,762 |
I45N |
probably benign |
Het |
| Rnmt |
T |
A |
18: 68,306,115 |
D98E |
possibly damaging |
Het |
| Rprd2 |
A |
G |
3: 95,785,059 |
F188L |
probably damaging |
Het |
| Scube2 |
G |
A |
7: 109,810,737 |
T643M |
probably damaging |
Het |
| Slc7a15 |
T |
C |
12: 8,539,344 |
I68V |
probably benign |
Het |
| Slco1a5 |
A |
T |
6: 142,242,125 |
V496D |
possibly damaging |
Het |
| Slitrk6 |
T |
G |
14: 110,751,217 |
S353R |
possibly damaging |
Het |
| Smpd5 |
T |
A |
15: 76,295,125 |
I53K |
possibly damaging |
Het |
| Tas2r108 |
T |
C |
6: 40,494,087 |
S166P |
probably benign |
Het |
| Tecpr1 |
C |
A |
5: 144,214,344 |
V245L |
possibly damaging |
Het |
| Tenm3 |
G |
T |
8: 48,236,764 |
N1929K |
probably damaging |
Het |
| Tigd5 |
T |
G |
15: 75,911,025 |
F412C |
probably damaging |
Het |
| Timm17a |
A |
T |
1: 135,306,188 |
S74T |
possibly damaging |
Het |
| Tle1 |
A |
T |
4: 72,139,808 |
L60Q |
probably damaging |
Het |
| Tmem132d |
T |
C |
5: 127,796,000 |
E515G |
possibly damaging |
Het |
| Tmem65 |
T |
C |
15: 58,794,397 |
N115S |
probably benign |
Het |
| Trmt5 |
C |
A |
12: 73,281,652 |
R259L |
possibly damaging |
Het |
| Ttc37 |
T |
C |
13: 76,185,200 |
W25R |
probably damaging |
Het |
| Vmn2r50 |
A |
T |
7: 10,050,089 |
W153R |
probably benign |
Het |
| Vwa3a |
T |
G |
7: 120,768,173 |
S184A |
probably benign |
Het |
| Zbtb25 |
A |
G |
12: 76,349,164 |
L428P |
possibly damaging |
Het |
| Zbtb49 |
C |
T |
5: 38,200,816 |
D698N |
probably damaging |
Het |
| Zbtb8os |
T |
G |
4: 129,340,735 |
D35E |
probably damaging |
Het |
| Zfp316 |
T |
C |
5: 143,264,491 |
T56A |
unknown |
Het |
| Zfp334 |
A |
T |
2: 165,380,487 |
C545* |
probably null |
Het |
| Zmiz1 |
C |
A |
14: 25,644,856 |
S247R |
probably damaging |
Het |
| Zscan18 |
A |
G |
7: 12,775,381 |
|
probably benign |
Het |
| Zzef1 |
T |
C |
11: 72,900,637 |
V2189A |
probably damaging |
Het |
|
| Other mutations in Dock9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Dock9
|
APN |
14 |
121,668,468 (GRCm38) |
missense |
probably benign |
0.12 |
|
IGL00817:Dock9
|
APN |
14 |
121,698,291 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL00923:Dock9
|
APN |
14 |
121,607,092 (GRCm38) |
unclassified |
probably benign |
|
|
IGL01385:Dock9
|
APN |
14 |
121,580,583 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01567:Dock9
|
APN |
14 |
121,653,084 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01767:Dock9
|
APN |
14 |
121,622,870 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL01811:Dock9
|
APN |
14 |
121,559,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02512:Dock9
|
APN |
14 |
121,619,538 (GRCm38) |
splice site |
probably benign |
|
|
IGL02525:Dock9
|
APN |
14 |
121,640,126 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02550:Dock9
|
APN |
14 |
121,698,312 (GRCm38) |
start codon destroyed |
probably null |
0.07 |
|
IGL02559:Dock9
|
APN |
14 |
121,625,147 (GRCm38) |
splice site |
probably benign |
|
|
IGL02666:Dock9
|
APN |
14 |
121,580,699 (GRCm38) |
missense |
probably benign |
0.42 |
|
IGL02674:Dock9
|
APN |
14 |
121,595,611 (GRCm38) |
splice site |
probably null |
|
|
IGL02795:Dock9
|
APN |
14 |
121,639,978 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL03074:Dock9
|
APN |
14 |
121,607,270 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL03095:Dock9
|
APN |
14 |
121,639,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03294:Dock9
|
APN |
14 |
121,641,623 (GRCm38) |
splice site |
probably benign |
|
|
R0036:Dock9
|
UTSW |
14 |
121,622,853 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0050:Dock9
|
UTSW |
14 |
121,607,225 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:Dock9
|
UTSW |
14 |
121,597,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0270:Dock9
|
UTSW |
14 |
121,575,999 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0494:Dock9
|
UTSW |
14 |
121,662,584 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R0726:Dock9
|
UTSW |
14 |
121,651,768 (GRCm38) |
nonsense |
probably null |
|
|
R1029:Dock9
|
UTSW |
14 |
121,599,684 (GRCm38) |
splice site |
probably null |
|
|
R1214:Dock9
|
UTSW |
14 |
121,586,316 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1231:Dock9
|
UTSW |
14 |
121,575,950 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R1535:Dock9
|
UTSW |
14 |
121,546,064 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1629:Dock9
|
UTSW |
14 |
121,543,574 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R1637:Dock9
|
UTSW |
14 |
121,651,775 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R1733:Dock9
|
UTSW |
14 |
121,626,880 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1772:Dock9
|
UTSW |
14 |
121,609,798 (GRCm38) |
missense |
probably benign |
0.07 |
|
R1855:Dock9
|
UTSW |
14 |
121,640,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1888:Dock9
|
UTSW |
14 |
121,625,205 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1901:Dock9
|
UTSW |
14 |
121,625,153 (GRCm38) |
splice site |
probably null |
|
|
R1920:Dock9
|
UTSW |
14 |
121,583,380 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1987:Dock9
|
UTSW |
14 |
121,591,830 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3035:Dock9
|
UTSW |
14 |
121,606,837 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R3851:Dock9
|
UTSW |
14 |
121,629,086 (GRCm38) |
splice site |
probably null |
|
|
R4020:Dock9
|
UTSW |
14 |
121,606,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4021:Dock9
|
UTSW |
14 |
121,626,912 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4089:Dock9
|
UTSW |
14 |
121,583,471 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4258:Dock9
|
UTSW |
14 |
121,581,442 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4423:Dock9
|
UTSW |
14 |
121,562,053 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4561:Dock9
|
UTSW |
14 |
121,559,007 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4604:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4646:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4647:Dock9
|
UTSW |
14 |
121,586,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4776:Dock9
|
UTSW |
14 |
121,610,097 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R4809:Dock9
|
UTSW |
14 |
121,546,596 (GRCm38) |
missense |
probably benign |
0.37 |
|
R4865:Dock9
|
UTSW |
14 |
121,543,505 (GRCm38) |
makesense |
probably null |
|
|
R4951:Dock9
|
UTSW |
14 |
121,653,135 (GRCm38) |
missense |
probably benign |
0.35 |
|
R5151:Dock9
|
UTSW |
14 |
121,578,170 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5359:Dock9
|
UTSW |
14 |
121,653,060 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5366:Dock9
|
UTSW |
14 |
121,578,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5502:Dock9
|
UTSW |
14 |
121,610,182 (GRCm38) |
splice site |
probably null |
|
|
R5753:Dock9
|
UTSW |
14 |
121,634,625 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5836:Dock9
|
UTSW |
14 |
121,681,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5858:Dock9
|
UTSW |
14 |
121,628,792 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5890:Dock9
|
UTSW |
14 |
121,668,408 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6075:Dock9
|
UTSW |
14 |
121,545,973 (GRCm38) |
missense |
probably benign |
|
|
R6298:Dock9
|
UTSW |
14 |
121,634,594 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6306:Dock9
|
UTSW |
14 |
121,562,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6321:Dock9
|
UTSW |
14 |
121,546,021 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6330:Dock9
|
UTSW |
14 |
121,605,243 (GRCm38) |
start codon destroyed |
probably null |
0.00 |
|
R6719:Dock9
|
UTSW |
14 |
121,610,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6784:Dock9
|
UTSW |
14 |
121,543,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6826:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6830:Dock9
|
UTSW |
14 |
121,622,918 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6838:Dock9
|
UTSW |
14 |
121,546,596 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6868:Dock9
|
UTSW |
14 |
121,586,264 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6919:Dock9
|
UTSW |
14 |
121,643,152 (GRCm38) |
missense |
probably benign |
0.42 |
|
R6989:Dock9
|
UTSW |
14 |
121,627,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7539:Dock9
|
UTSW |
14 |
121,581,436 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7645:Dock9
|
UTSW |
14 |
121,597,663 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7875:Dock9
|
UTSW |
14 |
121,625,984 (GRCm38) |
nonsense |
probably null |
|
|
R7900:Dock9
|
UTSW |
14 |
121,546,079 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8040:Dock9
|
UTSW |
14 |
121,651,794 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8420:Dock9
|
UTSW |
14 |
121,546,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,681,435 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,627,389 (GRCm38) |
missense |
probably benign |
0.40 |
|
R8514:Dock9
|
UTSW |
14 |
121,658,787 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8691:Dock9
|
UTSW |
14 |
121,640,105 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R8804:Dock9
|
UTSW |
14 |
121,605,183 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8894:Dock9
|
UTSW |
14 |
121,622,961 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8900:Dock9
|
UTSW |
14 |
121,580,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9069:Dock9
|
UTSW |
14 |
121,628,912 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9218:Dock9
|
UTSW |
14 |
121,668,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9233:Dock9
|
UTSW |
14 |
121,583,369 (GRCm38) |
missense |
probably benign |
0.09 |
|
R9236:Dock9
|
UTSW |
14 |
121,639,558 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9285:Dock9
|
UTSW |
14 |
121,595,600 (GRCm38) |
missense |
probably benign |
|
|
R9451:Dock9
|
UTSW |
14 |
121,550,189 (GRCm38) |
splice site |
probably benign |
|
|
R9461:Dock9
|
UTSW |
14 |
121,605,189 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9484:Dock9
|
UTSW |
14 |
121,581,432 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9517:Dock9
|
UTSW |
14 |
121,591,824 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9542:Dock9
|
UTSW |
14 |
121,627,363 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9694:Dock9
|
UTSW |
14 |
121,581,379 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9701:Dock9
|
UTSW |
14 |
121,639,571 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9703:Dock9
|
UTSW |
14 |
121,544,577 (GRCm38) |
makesense |
probably null |
|
|
R9726:Dock9
|
UTSW |
14 |
121,597,737 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9741:Dock9
|
UTSW |
14 |
121,640,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dock9
|
UTSW |
14 |
121,555,275 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Dock9
|
UTSW |
14 |
121,651,782 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCATTACCAGCAGCGACC -3'
(R):5'- GTACAACTCTCGAGCCATATGAC -3'
Sequencing Primer
(F):5'- GAGACAATGACTGAGTCACAATC -3'
(R):5'- TTAATGGCCACAAAAACACTTCCTC -3'
|
| Posted On |
2016-10-26 |
Incidental Mutation