Incidental Mutation 'R5580:Med13l'
| ID |
438376 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med13l
|
| Ensembl Gene |
ENSMUSG00000018076 |
| Gene Name |
mediator complex subunit 13-like |
| Synonyms |
9030618F05Rik, Trap240L, 6330591G05Rik, Thrap2, 2210413I17Rik |
| MMRRC Submission |
043134-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.966)
|
| Stock # |
R5580 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
118698744-118903503 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 118889695 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1819
(K1819E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144092
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100816]
[ENSMUST00000201010]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100816
AA Change: K1819E
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000098379
Gene: ENSMUSG00000018076
AA Change: K1819E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
2.5e-116 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2197 |
1e-142 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000201010
AA Change: K1819E
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000144092
Gene: ENSMUSG00000018076
AA Change: K1819E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
1e-112 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2206 |
1.7e-138 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202538
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202787
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410002F23Rik |
A |
G |
7: 43,900,664 (GRCm39) |
T73A |
possibly damaging |
Het |
| A1bg |
A |
T |
15: 60,790,881 (GRCm39) |
V365E |
probably benign |
Het |
| Abcg5 |
A |
C |
17: 84,967,582 (GRCm39) |
V406G |
probably damaging |
Het |
| Adamts12 |
A |
G |
15: 11,152,086 (GRCm39) |
Y192C |
probably benign |
Het |
| Add3 |
C |
T |
19: 53,233,642 (GRCm39) |
S649L |
probably damaging |
Het |
| Adgrg6 |
A |
T |
10: 14,286,228 (GRCm39) |
C1129* |
probably null |
Het |
| Arsb |
T |
A |
13: 93,944,053 (GRCm39) |
V248D |
probably damaging |
Het |
| AW554918 |
A |
T |
18: 25,472,922 (GRCm39) |
N39I |
probably damaging |
Het |
| Cacna1b |
A |
T |
2: 24,540,566 (GRCm39) |
I1383N |
probably damaging |
Het |
| Caprin2 |
A |
T |
6: 148,760,232 (GRCm39) |
V625D |
possibly damaging |
Het |
| Cd9 |
A |
G |
6: 125,441,420 (GRCm39) |
L67P |
probably damaging |
Het |
| Cdh5 |
T |
A |
8: 104,852,126 (GRCm39) |
Y80* |
probably null |
Het |
| Csf2ra |
A |
G |
19: 61,214,655 (GRCm39) |
L223P |
probably damaging |
Het |
| Cyp2c67 |
T |
C |
19: 39,604,094 (GRCm39) |
K421E |
probably damaging |
Het |
| Dzank1 |
T |
C |
2: 144,348,098 (GRCm39) |
R223G |
probably damaging |
Het |
| Emilin2 |
A |
G |
17: 71,582,225 (GRCm39) |
V167A |
probably benign |
Het |
| Eps8l3 |
A |
G |
3: 107,788,919 (GRCm39) |
T81A |
probably damaging |
Het |
| Esrra |
T |
C |
19: 6,897,755 (GRCm39) |
M1V |
probably null |
Het |
| Evpl |
C |
A |
11: 116,125,058 (GRCm39) |
A135S |
probably benign |
Het |
| Fam193a |
A |
G |
5: 34,578,132 (GRCm39) |
I209V |
probably benign |
Het |
| Fbxl19 |
C |
A |
7: 127,350,168 (GRCm39) |
C253* |
probably null |
Het |
| Fer1l5 |
T |
A |
1: 36,424,539 (GRCm39) |
Y305* |
probably null |
Het |
| Fzd2 |
A |
C |
11: 102,496,665 (GRCm39) |
I370L |
probably damaging |
Het |
| Gnl3 |
T |
C |
14: 30,737,242 (GRCm39) |
K212R |
probably benign |
Het |
| Golm1 |
A |
G |
13: 59,790,179 (GRCm39) |
L207P |
probably benign |
Het |
| Gphn |
T |
A |
12: 78,538,818 (GRCm39) |
F155I |
probably damaging |
Het |
| Grhl1 |
G |
A |
12: 24,659,739 (GRCm39) |
G500S |
probably benign |
Het |
| Gucd1 |
C |
A |
10: 75,346,968 (GRCm39) |
G55V |
possibly damaging |
Het |
| Haus6 |
A |
T |
4: 86,517,503 (GRCm39) |
I287K |
possibly damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,453,290 (GRCm39) |
P5342S |
probably benign |
Het |
| Hspa12a |
A |
G |
19: 58,788,092 (GRCm39) |
S577P |
probably benign |
Het |
| Ido2 |
T |
A |
8: 25,040,882 (GRCm39) |
I113F |
possibly damaging |
Het |
| Ifrd2 |
C |
T |
9: 107,469,511 (GRCm39) |
P396S |
probably damaging |
Het |
| Igkv4-86 |
T |
A |
6: 68,887,990 (GRCm39) |
|
probably benign |
Het |
| Ipo11 |
A |
G |
13: 107,037,255 (GRCm39) |
V196A |
probably benign |
Het |
| Itih2 |
T |
C |
2: 10,128,287 (GRCm39) |
E138G |
probably damaging |
Het |
| Kidins220 |
T |
G |
12: 25,097,896 (GRCm39) |
C1179G |
probably benign |
Het |
| Kif20b |
T |
A |
19: 34,927,128 (GRCm39) |
|
probably null |
Het |
| Klk1 |
T |
A |
7: 43,878,238 (GRCm39) |
Y63N |
probably benign |
Het |
| L3mbtl3 |
T |
G |
10: 26,179,604 (GRCm39) |
D517A |
unknown |
Het |
| Lars1 |
G |
T |
18: 42,347,916 (GRCm39) |
P969H |
probably damaging |
Het |
| Lrp1 |
C |
T |
10: 127,424,389 (GRCm39) |
V766I |
probably benign |
Het |
| Lrrc8c |
A |
G |
5: 105,755,553 (GRCm39) |
I443V |
probably benign |
Het |
| Lsg1 |
T |
C |
16: 30,387,985 (GRCm39) |
M439V |
probably null |
Het |
| Magi2 |
T |
A |
5: 20,420,422 (GRCm39) |
M286K |
probably benign |
Het |
| Med11 |
T |
C |
11: 70,342,891 (GRCm39) |
|
probably null |
Het |
| Ms4a14 |
T |
A |
19: 11,280,590 (GRCm39) |
Q656L |
probably benign |
Het |
| Muc5b |
A |
G |
7: 141,415,084 (GRCm39) |
T2677A |
possibly damaging |
Het |
| Myo7a |
A |
T |
7: 97,722,367 (GRCm39) |
L1186H |
probably damaging |
Het |
| Naca |
C |
A |
10: 127,876,462 (GRCm39) |
|
probably benign |
Het |
| Nbeal1 |
T |
C |
1: 60,281,761 (GRCm39) |
I828T |
probably benign |
Het |
| Ncor1 |
A |
T |
11: 62,280,604 (GRCm39) |
C75* |
probably null |
Het |
| Nepn |
A |
C |
10: 52,280,398 (GRCm39) |
S497R |
probably damaging |
Het |
| Nf2 |
A |
G |
11: 4,753,689 (GRCm39) |
F222L |
probably damaging |
Het |
| Nlrp9b |
A |
C |
7: 19,757,089 (GRCm39) |
T109P |
probably damaging |
Het |
| Nr1h4 |
A |
T |
10: 89,352,302 (GRCm39) |
F22I |
probably benign |
Het |
| Ogg1 |
A |
G |
6: 113,306,337 (GRCm39) |
Y178C |
probably damaging |
Het |
| Or1e22 |
G |
T |
11: 73,377,036 (GRCm39) |
P205T |
probably benign |
Het |
| Or4b12 |
C |
A |
2: 90,096,694 (GRCm39) |
V27L |
probably benign |
Het |
| Or5b119 |
T |
A |
19: 13,456,791 (GRCm39) |
Y257F |
probably damaging |
Het |
| Or5b21 |
G |
A |
19: 12,839,168 (GRCm39) |
V10M |
possibly damaging |
Het |
| Or5d14 |
A |
T |
2: 87,880,668 (GRCm39) |
M100K |
possibly damaging |
Het |
| Osr1 |
G |
A |
12: 9,629,325 (GRCm39) |
R66Q |
probably damaging |
Het |
| Pi4ka |
A |
G |
16: 17,098,951 (GRCm39) |
S1978P |
probably damaging |
Het |
| Pik3c2g |
A |
T |
6: 139,603,531 (GRCm39) |
Q239L |
probably damaging |
Het |
| Pin1rt1 |
A |
G |
2: 104,544,670 (GRCm39) |
I154T |
probably damaging |
Het |
| Pkdcc |
A |
G |
17: 83,527,511 (GRCm39) |
T230A |
probably damaging |
Het |
| Por |
A |
T |
5: 135,762,675 (GRCm39) |
I430F |
probably damaging |
Het |
| Prb1c |
T |
C |
6: 132,338,432 (GRCm39) |
N262S |
unknown |
Het |
| Prkcsh |
T |
A |
9: 21,922,551 (GRCm39) |
|
probably null |
Het |
| Pros1 |
A |
G |
16: 62,746,689 (GRCm39) |
|
probably null |
Het |
| Pus10 |
T |
A |
11: 23,622,556 (GRCm39) |
L59I |
probably benign |
Het |
| Pxmp2 |
A |
G |
5: 110,431,542 (GRCm39) |
V67A |
possibly damaging |
Het |
| Rab3gap1 |
C |
A |
1: 127,858,727 (GRCm39) |
A612E |
probably benign |
Het |
| Rpap2 |
A |
G |
5: 107,768,011 (GRCm39) |
E206G |
probably benign |
Het |
| Rpl31 |
C |
T |
1: 39,409,108 (GRCm39) |
R41C |
probably benign |
Het |
| Ryr3 |
C |
T |
2: 112,672,293 (GRCm39) |
G1393R |
probably damaging |
Het |
| Scara5 |
T |
C |
14: 65,968,528 (GRCm39) |
M267T |
probably benign |
Het |
| Sema5a |
A |
T |
15: 32,575,031 (GRCm39) |
I380F |
probably benign |
Het |
| Slc36a3 |
A |
G |
11: 55,026,279 (GRCm39) |
S180P |
probably benign |
Het |
| Slc44a5 |
A |
G |
3: 153,966,922 (GRCm39) |
K536R |
probably benign |
Het |
| Smg1 |
T |
C |
7: 117,748,125 (GRCm39) |
|
probably benign |
Het |
| Spata31d1e |
A |
T |
13: 59,890,070 (GRCm39) |
D583E |
probably benign |
Het |
| Strc |
T |
C |
2: 121,205,493 (GRCm39) |
K879R |
probably damaging |
Het |
| Swt1 |
T |
C |
1: 151,260,206 (GRCm39) |
E731G |
probably benign |
Het |
| Syngap1 |
G |
A |
17: 27,181,305 (GRCm39) |
A9T |
probably damaging |
Het |
| Tex15 |
C |
T |
8: 34,062,457 (GRCm39) |
T903I |
probably damaging |
Het |
| Tg |
A |
G |
15: 66,557,149 (GRCm39) |
I937V |
possibly damaging |
Het |
| Tm9sf4 |
T |
C |
2: 153,024,350 (GRCm39) |
Y58H |
probably damaging |
Het |
| Tsen2 |
A |
T |
6: 115,554,941 (GRCm39) |
D458V |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,748,146 (GRCm39) |
D4301V |
probably benign |
Het |
| Txk |
C |
A |
5: 72,864,932 (GRCm39) |
L314F |
probably damaging |
Het |
| Ube3b |
A |
G |
5: 114,553,384 (GRCm39) |
T919A |
probably benign |
Het |
| Ubn2 |
A |
G |
6: 38,460,187 (GRCm39) |
M641V |
probably damaging |
Het |
| Usp4 |
C |
T |
9: 108,243,058 (GRCm39) |
T242I |
probably benign |
Het |
| Usp53 |
A |
G |
3: 122,727,883 (GRCm39) |
S900P |
probably benign |
Het |
| Vmn1r225 |
T |
C |
17: 20,723,101 (GRCm39) |
Y181H |
probably damaging |
Het |
| Vmn1r83 |
T |
A |
7: 12,055,800 (GRCm39) |
I86L |
probably benign |
Het |
| Vmn2r65 |
T |
C |
7: 84,596,802 (GRCm39) |
I84M |
probably damaging |
Het |
| Vstm2b |
A |
G |
7: 40,552,050 (GRCm39) |
H126R |
probably damaging |
Het |
| Zfp524 |
A |
T |
7: 5,021,416 (GRCm39) |
I315F |
probably benign |
Het |
| Zfp975 |
A |
T |
7: 42,314,513 (GRCm39) |
L20* |
probably null |
Het |
|
| Other mutations in Med13l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Med13l
|
APN |
5 |
118,862,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01012:Med13l
|
APN |
5 |
118,872,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01316:Med13l
|
APN |
5 |
118,900,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01529:Med13l
|
APN |
5 |
118,880,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01731:Med13l
|
APN |
5 |
118,880,472 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01790:Med13l
|
APN |
5 |
118,731,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02394:Med13l
|
APN |
5 |
118,886,898 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL02432:Med13l
|
APN |
5 |
118,876,465 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02698:Med13l
|
APN |
5 |
118,900,894 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02801:Med13l
|
APN |
5 |
118,883,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03242:Med13l
|
APN |
5 |
118,885,510 (GRCm39) |
missense |
probably benign |
|
|
IGL03270:Med13l
|
APN |
5 |
118,869,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Basics
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
firmament
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
Fundament
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Root
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0035:Med13l
|
UTSW |
5 |
118,880,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0136:Med13l
|
UTSW |
5 |
118,862,115 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0158:Med13l
|
UTSW |
5 |
118,880,514 (GRCm39) |
missense |
unknown |
|
|
R0197:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0370:Med13l
|
UTSW |
5 |
118,879,891 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0492:Med13l
|
UTSW |
5 |
118,876,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Med13l
|
UTSW |
5 |
118,897,188 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0726:Med13l
|
UTSW |
5 |
118,886,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Med13l
|
UTSW |
5 |
118,889,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0827:Med13l
|
UTSW |
5 |
118,864,312 (GRCm39) |
splice site |
probably benign |
|
|
R0883:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0959:Med13l
|
UTSW |
5 |
118,892,350 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1458:Med13l
|
UTSW |
5 |
118,876,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1562:Med13l
|
UTSW |
5 |
118,876,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Med13l
|
UTSW |
5 |
118,859,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1661:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Med13l
|
UTSW |
5 |
118,880,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1929:Med13l
|
UTSW |
5 |
118,866,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1967:Med13l
|
UTSW |
5 |
118,899,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2301:Med13l
|
UTSW |
5 |
118,731,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3691:Med13l
|
UTSW |
5 |
118,859,562 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3895:Med13l
|
UTSW |
5 |
118,899,388 (GRCm39) |
missense |
probably null |
0.99 |
|
R4043:Med13l
|
UTSW |
5 |
118,731,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4593:Med13l
|
UTSW |
5 |
118,880,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Med13l
|
UTSW |
5 |
118,883,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Med13l
|
UTSW |
5 |
118,869,014 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5010:Med13l
|
UTSW |
5 |
118,731,615 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5057:Med13l
|
UTSW |
5 |
118,856,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5369:Med13l
|
UTSW |
5 |
118,862,075 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5446:Med13l
|
UTSW |
5 |
118,880,462 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5564:Med13l
|
UTSW |
5 |
118,880,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Med13l
|
UTSW |
5 |
118,866,730 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5634:Med13l
|
UTSW |
5 |
118,698,915 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5748:Med13l
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5764:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5765:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6083:Med13l
|
UTSW |
5 |
118,859,551 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6504:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6546:Med13l
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6797:Med13l
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6911:Med13l
|
UTSW |
5 |
118,893,723 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6942:Med13l
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
R7018:Med13l
|
UTSW |
5 |
118,890,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7096:Med13l
|
UTSW |
5 |
118,859,991 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7113:Med13l
|
UTSW |
5 |
118,864,330 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7136:Med13l
|
UTSW |
5 |
118,859,587 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7140:Med13l
|
UTSW |
5 |
118,880,037 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7345:Med13l
|
UTSW |
5 |
118,880,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7409:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7410:Med13l
|
UTSW |
5 |
118,698,897 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7432:Med13l
|
UTSW |
5 |
118,890,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7486:Med13l
|
UTSW |
5 |
118,866,539 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7509:Med13l
|
UTSW |
5 |
118,886,995 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7722:Med13l
|
UTSW |
5 |
118,885,472 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7802:Med13l
|
UTSW |
5 |
118,866,655 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8081:Med13l
|
UTSW |
5 |
118,866,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Med13l
|
UTSW |
5 |
118,886,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8266:Med13l
|
UTSW |
5 |
118,880,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8347:Med13l
|
UTSW |
5 |
118,880,662 (GRCm39) |
missense |
probably benign |
|
|
R8365:Med13l
|
UTSW |
5 |
118,866,709 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8508:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8920:Med13l
|
UTSW |
5 |
118,885,543 (GRCm39) |
nonsense |
probably null |
|
|
R8970:Med13l
|
UTSW |
5 |
118,883,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8994:Med13l
|
UTSW |
5 |
118,866,226 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9045:Med13l
|
UTSW |
5 |
118,880,816 (GRCm39) |
missense |
probably benign |
|
|
R9401:Med13l
|
UTSW |
5 |
118,883,089 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9445:Med13l
|
UTSW |
5 |
118,862,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9446:Med13l
|
UTSW |
5 |
118,876,567 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9714:Med13l
|
UTSW |
5 |
118,866,438 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9777:Med13l
|
UTSW |
5 |
118,887,024 (GRCm39) |
missense |
probably benign |
|
|
R9781:Med13l
|
UTSW |
5 |
118,868,032 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9797:Med13l
|
UTSW |
5 |
118,880,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:Med13l
|
UTSW |
5 |
118,867,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Med13l
|
UTSW |
5 |
118,887,706 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGAACAGCCTGTTGTCGGTG -3'
(R):5'- GCAGGGCACACTTTCTAAGC -3'
Sequencing Primer
(F):5'- TGTTGTCGGTGCCCCCTG -3'
(R):5'- GGCACACTTTCTAAGCGCAGAG -3'
|
| Posted On |
2016-10-26 |
Incidental Mutation